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The map label for this gene is kup [H]

Identifier: 148360171

GI number: 148360171

Start: 2863623

End: 2865512

Strand: Direct

Name: kup [H]

Synonym: LPC_2102

Alternate gene names: 148360171

Gene position: 2863623-2865512 (Clockwise)

Preceding gene: 148360172

Following gene: 148360170

Centisome position: 80.07

GC content: 40.21

Gene sequence:

>1890_bases
ATGCCCTCAACAAGAAACATTGAAACGCATAACGACTCCAATCCCACATTGCGAGCACTGAGTCTATCTGCCTTGGGCAT
AGTTTACGGAGATATTGGAACAAGCCCTCTTTATACTTTTAAAACGGTTATATTGCTGGCGGGAGGAGGGACTCCAGACG
TAACTACCATTATGGGTTCGGCATCATTGATTATATGGACTCTGATAATCATCGCGTCTGTTAAATATATTTGCTTTGCT
TTACGGATTGACAACGATGGAGAGGGAGGGATTCTCGCGTTGATGTCTCTTTTAAGTTTAAAACTAAAACAAAAGCCTTT
CATTATCGCGGTTGGACTTATGGGGGCTGCTCTTATCTATGGAGATGGCACAATTACCCCAGCCATATCGGTGCTCTCTG
CTGTAGAGGGACTTGAAATCCTTTCCCCATCACTTAAGTATTATGTTTTGCCTATTGCGATAACAATTCTGATAACACTT
TTTGCGATTCAATCTAAAGGTACCGCAACTATTGGAAAGGCCTTTGGCCCAGTGATGGCATTTTGGTTTTTAACCATTGG
TATTTTAGGGGCAAGAGAAGTTATCCAACACCCTTTTGTCTTAGCGGCGATAAACCCTGTTTATGGCTTAAATTTTTTAT
TTTCAAATGGTGCAACAGGATTTTTTATTTTATGTGGGGTGTTTCTTTGTGTCACTGGTGCAGAAGCTTTATACGCCGAT
CTGGGACATTTTGGTACCGCCCCAATTCGCTGCGCCTGGTTTGGTCTGGCTTTTCCAAGCCTTATCTTTAACTATCTGGG
ACAAGCCGCTTTGGTTTTGGAAGGAGCATCTACAGAGCATAATATTTTTTACATGCTGTGCCCAAGTGATTTTTTATTAC
CGTTAATAATTCTGTCTACCGTCGCAACAATTATTGCCAGCCAAGCCATTATTACCGGGGCATTTTCCATGACAAGACAA
GCAATGCAACTGGGCTGGCTGCCAAGGTTACGAGTCACGCAAACGTCTTCAGAAGGATATGGGCAAATTTATATAGGAGT
TGTTAACTGGCTTTTAATGCTGGCTACCCTTGGGCTTATTATCGGATTTGGGAGTTCTGAAAAATTGGCTGCTGCCTATG
GCATTGCTGTTTCAGCCACTATGCTTTGCACCTCTGTGCTTTTATTTATTGCGCTGCATAAACTATGGAAGTGGAATATT
ATCAAATCAGGGCTTGTTGCTGGATTATTCATGATTGTCGATGCCTCTTTTTTTGCGGCCAATCTCACGAAATTTATCAA
TGGCGGATATATACCAATCACATTGGCAATCATAATCTATTCCATGATGTATATTTGGCATAAAGGCTATAAAACCATCG
CGATCAAGCAAAAAGAAAAAAATATAACAGTCGATTCCTTTCTGGACAGTATTCAAAAAGAGGGGGTAGTCCGTGTGCCT
AAAACTGCTGTTTTTCTTACATCCAAGGAGCAGGATATTCCTCCAACCCTGGTTTGGCATGTAAAGAAAAATCATGTGTT
GCAGGATAAGGTTATTATTTTAAATATTAACAACTTGTCCATTCCCTGGTGTAAACCTGGTGATCAATTACAAATTGTAG
AAACAGGAGCAGGCATCTGGCATGCCGTAGCAAATTATGGCTTTATGGAACAACCTCATATTCCAAAATTATTAAAGAAA
TTAGAAACTCAAGGCTATGACATCAATATCAAAGACATAACCTATTATATCGGTCATGAAACAATATTTGTCCGCAATGT
CCGTCATACTCTGTCAAAATACATTAAAATTCTCTTCGTTTTTATGCATCGCAATGCCCTTCCCATGAGTAACTACTTTC
ATCTTCCGCCGGAATCAGTATTTGAAATAGGACGACAGATAGAAATTTAG

Upstream 100 bases:

>100_bases
TTCAAAGAATTAGATTAATTTATCTAAGATTGAAGTGCCACTTATTGGAGGATAGCCCCTCCTTTTGAGTAAAGCCAAAC
TTAATGAGAGAGCCAACTCA

Downstream 100 bases:

>100_bases
TGAAAATAATTGCTCCCTGACATGGAAAATCTCAGTGGGCGAGCACAGTTTTATGGTCAGGATTGAATTTTGCACCTGGT
CCTATAGCACATGTGACAAA

Product: Kup system potassium uptake protein

Products: K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 629; Mature: 628

Protein sequence:

>629_residues
MPSTRNIETHNDSNPTLRALSLSALGIVYGDIGTSPLYTFKTVILLAGGGTPDVTTIMGSASLIIWTLIIIASVKYICFA
LRIDNDGEGGILALMSLLSLKLKQKPFIIAVGLMGAALIYGDGTITPAISVLSAVEGLEILSPSLKYYVLPIAITILITL
FAIQSKGTATIGKAFGPVMAFWFLTIGILGAREVIQHPFVLAAINPVYGLNFLFSNGATGFFILCGVFLCVTGAEALYAD
LGHFGTAPIRCAWFGLAFPSLIFNYLGQAALVLEGASTEHNIFYMLCPSDFLLPLIILSTVATIIASQAIITGAFSMTRQ
AMQLGWLPRLRVTQTSSEGYGQIYIGVVNWLLMLATLGLIIGFGSSEKLAAAYGIAVSATMLCTSVLLFIALHKLWKWNI
IKSGLVAGLFMIVDASFFAANLTKFINGGYIPITLAIIIYSMMYIWHKGYKTIAIKQKEKNITVDSFLDSIQKEGVVRVP
KTAVFLTSKEQDIPPTLVWHVKKNHVLQDKVIILNINNLSIPWCKPGDQLQIVETGAGIWHAVANYGFMEQPHIPKLLKK
LETQGYDINIKDITYYIGHETIFVRNVRHTLSKYIKILFVFMHRNALPMSNYFHLPPESVFEIGRQIEI

Sequences:

>Translated_629_residues
MPSTRNIETHNDSNPTLRALSLSALGIVYGDIGTSPLYTFKTVILLAGGGTPDVTTIMGSASLIIWTLIIIASVKYICFA
LRIDNDGEGGILALMSLLSLKLKQKPFIIAVGLMGAALIYGDGTITPAISVLSAVEGLEILSPSLKYYVLPIAITILITL
FAIQSKGTATIGKAFGPVMAFWFLTIGILGAREVIQHPFVLAAINPVYGLNFLFSNGATGFFILCGVFLCVTGAEALYAD
LGHFGTAPIRCAWFGLAFPSLIFNYLGQAALVLEGASTEHNIFYMLCPSDFLLPLIILSTVATIIASQAIITGAFSMTRQ
AMQLGWLPRLRVTQTSSEGYGQIYIGVVNWLLMLATLGLIIGFGSSEKLAAAYGIAVSATMLCTSVLLFIALHKLWKWNI
IKSGLVAGLFMIVDASFFAANLTKFINGGYIPITLAIIIYSMMYIWHKGYKTIAIKQKEKNITVDSFLDSIQKEGVVRVP
KTAVFLTSKEQDIPPTLVWHVKKNHVLQDKVIILNINNLSIPWCKPGDQLQIVETGAGIWHAVANYGFMEQPHIPKLLKK
LETQGYDINIKDITYYIGHETIFVRNVRHTLSKYIKILFVFMHRNALPMSNYFHLPPESVFEIGRQIEI
>Mature_628_residues
PSTRNIETHNDSNPTLRALSLSALGIVYGDIGTSPLYTFKTVILLAGGGTPDVTTIMGSASLIIWTLIIIASVKYICFAL
RIDNDGEGGILALMSLLSLKLKQKPFIIAVGLMGAALIYGDGTITPAISVLSAVEGLEILSPSLKYYVLPIAITILITLF
AIQSKGTATIGKAFGPVMAFWFLTIGILGAREVIQHPFVLAAINPVYGLNFLFSNGATGFFILCGVFLCVTGAEALYADL
GHFGTAPIRCAWFGLAFPSLIFNYLGQAALVLEGASTEHNIFYMLCPSDFLLPLIILSTVATIIASQAIITGAFSMTRQA
MQLGWLPRLRVTQTSSEGYGQIYIGVVNWLLMLATLGLIIGFGSSEKLAAAYGIAVSATMLCTSVLLFIALHKLWKWNII
KSGLVAGLFMIVDASFFAANLTKFINGGYIPITLAIIIYSMMYIWHKGYKTIAIKQKEKNITVDSFLDSIQKEGVVRVPK
TAVFLTSKEQDIPPTLVWHVKKNHVLQDKVIILNINNLSIPWCKPGDQLQIVETGAGIWHAVANYGFMEQPHIPKLLKKL
ETQGYDINIKDITYYIGHETIFVRNVRHTLSKYIKILFVFMHRNALPMSNYFHLPPESVFEIGRQIEI

Specific function: Transport of potassium into the cell [H]

COG id: COG3158

COG function: function code P; K+ transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAK/KUP transporter (TC 2.A.72) family [H]

Homologues:

Organism=Escherichia coli, GI48994960, Length=621, Percent_Identity=39.7745571658615, Blast_Score=485, Evalue=1e-138,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003855
- InterPro:   IPR023051 [H]

Pfam domain/function: PF02705 K_trans [H]

EC number: NA

Molecular weight: Translated: 68916; Mature: 68784

Theoretical pI: Translated: 8.98; Mature: 8.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSTRNIETHNDSNPTLRALSLSALGIVYGDIGTSPLYTFKTVILLAGGGTPDVTTIMGS
CCCCCCCCCCCCCCCCEEEEEHHHHEEEEECCCCCCHHHEEEEEEEECCCCCCHHHHHCC
ASLIIWTLIIIASVKYICFALRIDNDGEGGILALMSLLSLKLKQKPFIIAVGLMGAALIY
HHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEEEHHCEEEEE
GDGTITPAISVLSAVEGLEILSPSLKYYVLPIAITILITLFAIQSKGTATIGKAFGPVMA
CCCCHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
FWFLTIGILGAREVIQHPFVLAAINPVYGLNFLFSNGATGFFILCGVFLCVTGAEALYAD
HHHHHHHHHHHHHHHHCCEEEEECCCHHCCEEEECCCCCHHHHHHHHHHHHHCHHHHHHH
LGHFGTAPIRCAWFGLAFPSLIFNYLGQAALVLEGASTEHNIFYMLCPSDFLLPLIILST
HHCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCEEEEECCCHHHHHHHHHHH
VATIIASQAIITGAFSMTRQAMQLGWLPRLRVTQTSSEGYGQIYIGVVNWLLMLATLGLI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEHHHHHHHHHHHHHHHH
IGFGSSEKLAAAYGIAVSATMLCTSVLLFIALHKLWKWNIIKSGLVAGLFMIVDASFFAA
EECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NLTKFINGGYIPITLAIIIYSMMYIWHKGYKTIAIKQKEKNITVDSFLDSIQKEGVVRVP
HHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHCCCEECC
KTAVFLTSKEQDIPPTLVWHVKKNHVLQDKVIILNINNLSIPWCKPGDQLQIVETGAGIW
CEEEEEECCCCCCCCEEEEEECCCCEEECEEEEEEECCEECCCCCCCCCEEEEECCCHHH
HAVANYGFMEQPHIPKLLKKLETQGYDINIKDITYYIGHETIFVRNVRHTLSKYIKILFV
HHHHCCCCCCCCCHHHHHHHHHCCCCEEEEEEEEEEECCCEEEEHHHHHHHHHHHHHHHH
FMHRNALPMSNYFHLPPESVFEIGRQIEI
HHHCCCCCCCCEECCCHHHHHHHCCCCCC
>Mature Secondary Structure 
PSTRNIETHNDSNPTLRALSLSALGIVYGDIGTSPLYTFKTVILLAGGGTPDVTTIMGS
CCCCCCCCCCCCCCCEEEEEHHHHEEEEECCCCCCHHHEEEEEEEECCCCCCHHHHHCC
ASLIIWTLIIIASVKYICFALRIDNDGEGGILALMSLLSLKLKQKPFIIAVGLMGAALIY
HHHHHHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEEEHHCEEEEE
GDGTITPAISVLSAVEGLEILSPSLKYYVLPIAITILITLFAIQSKGTATIGKAFGPVMA
CCCCHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
FWFLTIGILGAREVIQHPFVLAAINPVYGLNFLFSNGATGFFILCGVFLCVTGAEALYAD
HHHHHHHHHHHHHHHHCCEEEEECCCHHCCEEEECCCCCHHHHHHHHHHHHHCHHHHHHH
LGHFGTAPIRCAWFGLAFPSLIFNYLGQAALVLEGASTEHNIFYMLCPSDFLLPLIILST
HHCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCEEEEECCCHHHHHHHHHHH
VATIIASQAIITGAFSMTRQAMQLGWLPRLRVTQTSSEGYGQIYIGVVNWLLMLATLGLI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEHHHHHHHHHHHHHHHH
IGFGSSEKLAAAYGIAVSATMLCTSVLLFIALHKLWKWNIIKSGLVAGLFMIVDASFFAA
EECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NLTKFINGGYIPITLAIIIYSMMYIWHKGYKTIAIKQKEKNITVDSFLDSIQKEGVVRVP
HHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHCCCEECC
KTAVFLTSKEQDIPPTLVWHVKKNHVLQDKVIILNINNLSIPWCKPGDQLQIVETGAGIW
CEEEEEECCCCCCCCEEEEEECCCCEEECEEEEEEECCEECCCCCCCCCEEEEECCCHHH
HAVANYGFMEQPHIPKLLKKLETQGYDINIKDITYYIGHETIFVRNVRHTLSKYIKILFV
HHHHCCCCCCCCCHHHHHHHHHCCCCEEEEEEEEEEECCCEEEEHHHHHHHHHHHHHHHH
FMHRNALPMSNYFHLPPESVFEIGRQIEI
HHHCCCCCCCCEECCCHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: K (I) [Periplasm] [C]

Specific reaction: K (I) [Periplasm] = K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA