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The map label for this gene is ampC [H]

Identifier: 148360131

GI number: 148360131

Start: 2910226

End: 2911305

Strand: Direct

Name: ampC [H]

Synonym: LPC_2062

Alternate gene names: 148360131

Gene position: 2910226-2911305 (Clockwise)

Preceding gene: 148360134

Following gene: 148360130

Centisome position: 81.37

GC content: 37.22

Gene sequence:

>1080_bases
ATGAAATCAAAATACATTAGCTTATGCTTTTTTTCACTCATTTTATGGTTTGGCAGTCCAATTCTTTTGGCACAACCATC
CAGGCTGGATAATTTAATTAATCAACTGGTTCAACCATTTATTTATGCACATCAGACTCCCGGATTAGCCATTGCCATTT
ATTATAATGGAAAGGATTATTATTATAATTTTGGATTTGCTGACAGGAAAAGTAAGAAGCCAGTCACTAAAAATACTATT
TTTGAATTGGCATCGATTACCAAAATATTCATTAGCACTCTTGTAGCCCTGGAAGTTCAGAAAGGAAAATTGAACGTAAC
AGATTATGCCGTTCAATATACGCCCGAACTTTCAAAAACCAATGGACTACCAATTGACAGGGTTCAAATTGTGCATCTGG
CGACGCACACAGCAAGCTTTCCCAAACAAATGGAGCAATTTGGAGTTAATAAAGGCAATATACAGGCTTTCTTTGCCCGT
CTTAAAACATGGCGTCCTCCAGTAAAAATAGGAACTCATTATAAATATTCCAATATTGGTTTTGGGTATTTGGGATACGT
ATTGGAAAACGCCTCAAACGAGACTTTACCTAATCTGTTAAAATCGAATATTACCAAGCCATTGGGAATGTCCCATACTT
TTTTCAATGTACCAGAAAGTCTGGCTAACTATGAAGCTCAAGGTTATCGACCTAAAAACAAGCCAGCACCTTATTATACA
CCTGCCAACTTTCTAGGTGGAGGAGCTTTACGCTCTTCTGCAGCTGACATGTTGGTATTTTTAAAAGCAAATTTAGGAAT
TCAACCTGGAACCGCATCACCAGAATTACTTTCTGCGATGCAGTATGCCCAACAACCGTTTTTTGAAGTCAACCCAAATT
TTGTTATGGGATTAGGTTGGCAAAGAGTTAAAAGAGAGAGGCACATTGTGATCACTAAAAATGGAGCAAATCAGGGATTT
AGCACCTTTATTGGTTTTTCTCCTGCGAAAAAACTTGGAGTAATCGTATTAATCAACCAAGCAAGAGGTAAAGCAACTGC
ATTAGGCAACCAAATACTTAATAGCCTTCTTGGTTTATAA

Upstream 100 bases:

>100_bases
TGGACCTCTTACATAGCCAGGATAGAATCGCTGCAACATGACCTGATGAGGCAAAATAAAGAAAAGATAATTATTATATT
TTTCCAAAAAGACATTAATC

Downstream 100 bases:

>100_bases
TTCATACATTGGCACAAAAGTTAATACTGTCTTTCATAAGCAAGTCACACAACACTTAAAAGCTATTTGTTTGTTAAGAA
TAGATTCACGGGCATTGACA

Product: beta-lactamase

Products: NA

Alternate protein names: Cephalosporinase [H]

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MKSKYISLCFFSLILWFGSPILLAQPSRLDNLINQLVQPFIYAHQTPGLAIAIYYNGKDYYYNFGFADRKSKKPVTKNTI
FELASITKIFISTLVALEVQKGKLNVTDYAVQYTPELSKTNGLPIDRVQIVHLATHTASFPKQMEQFGVNKGNIQAFFAR
LKTWRPPVKIGTHYKYSNIGFGYLGYVLENASNETLPNLLKSNITKPLGMSHTFFNVPESLANYEAQGYRPKNKPAPYYT
PANFLGGGALRSSAADMLVFLKANLGIQPGTASPELLSAMQYAQQPFFEVNPNFVMGLGWQRVKRERHIVITKNGANQGF
STFIGFSPAKKLGVIVLINQARGKATALGNQILNSLLGL

Sequences:

>Translated_359_residues
MKSKYISLCFFSLILWFGSPILLAQPSRLDNLINQLVQPFIYAHQTPGLAIAIYYNGKDYYYNFGFADRKSKKPVTKNTI
FELASITKIFISTLVALEVQKGKLNVTDYAVQYTPELSKTNGLPIDRVQIVHLATHTASFPKQMEQFGVNKGNIQAFFAR
LKTWRPPVKIGTHYKYSNIGFGYLGYVLENASNETLPNLLKSNITKPLGMSHTFFNVPESLANYEAQGYRPKNKPAPYYT
PANFLGGGALRSSAADMLVFLKANLGIQPGTASPELLSAMQYAQQPFFEVNPNFVMGLGWQRVKRERHIVITKNGANQGF
STFIGFSPAKKLGVIVLINQARGKATALGNQILNSLLGL
>Mature_359_residues
MKSKYISLCFFSLILWFGSPILLAQPSRLDNLINQLVQPFIYAHQTPGLAIAIYYNGKDYYYNFGFADRKSKKPVTKNTI
FELASITKIFISTLVALEVQKGKLNVTDYAVQYTPELSKTNGLPIDRVQIVHLATHTASFPKQMEQFGVNKGNIQAFFAR
LKTWRPPVKIGTHYKYSNIGFGYLGYVLENASNETLPNLLKSNITKPLGMSHTFFNVPESLANYEAQGYRPKNKPAPYYT
PANFLGGGALRSSAADMLVFLKANLGIQPGTASPELLSAMQYAQQPFFEVNPNFVMGLGWQRVKRERHIVITKNGANQGF
STFIGFSPAKKLGVIVLINQARGKATALGNQILNSLLGL

Specific function: This protein is a serine beta-lactamase with a substrate specificity for cephalosporins [H]

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-C beta-lactamase family [H]

Homologues:

Organism=Escherichia coli, GI1790593, Length=375, Percent_Identity=27.2, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1786574, Length=355, Percent_Identity=22.5352112676056, Blast_Score=88, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001586
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: =3.5.2.6 [H]

Molecular weight: Translated: 39921; Mature: 39921

Theoretical pI: Translated: 10.33; Mature: 10.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSKYISLCFFSLILWFGSPILLAQPSRLDNLINQLVQPFIYAHQTPGLAIAIYYNGKDY
CCCHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCEE
YYNFGFADRKSKKPVTKNTIFELASITKIFISTLVALEVQKGKLNVTDYAVQYTPELSKT
EEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEECCCEEEEEEEEEEECCCCCCC
NGLPIDRVQIVHLATHTASFPKQMEQFGVNKGNIQAFFARLKTWRPPVKIGTHYKYSNIG
CCCCCCCEEEEEEEHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCEEEECCCC
FGYLGYVLENASNETLPNLLKSNITKPLGMSHTFFNVPESLANYEAQGYRPKNKPAPYYT
HHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCHHHCCCHHHHCCCCCCCCCCCCCCCCCC
PANFLGGGALRSSAADMLVFLKANLGIQPGTASPELLSAMQYAQQPFFEVNPNFVMGLGW
CHHHCCCHHHHHHHHHEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCEECCCCEEEECCH
QRVKRERHIVITKNGANQGFSTFIGFSPAKKLGVIVLINQARGKATALGNQILNSLLGL
HHHCCCCEEEEEECCCCCCCHHHHCCCCHHHCCEEEEEECCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKSKYISLCFFSLILWFGSPILLAQPSRLDNLINQLVQPFIYAHQTPGLAIAIYYNGKDY
CCCHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCEE
YYNFGFADRKSKKPVTKNTIFELASITKIFISTLVALEVQKGKLNVTDYAVQYTPELSKT
EEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEECCCEEEEEEEEEEECCCCCCC
NGLPIDRVQIVHLATHTASFPKQMEQFGVNKGNIQAFFARLKTWRPPVKIGTHYKYSNIG
CCCCCCCEEEEEEEHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCEEEECCCC
FGYLGYVLENASNETLPNLLKSNITKPLGMSHTFFNVPESLANYEAQGYRPKNKPAPYYT
HHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCHHHCCCHHHHCCCCCCCCCCCCCCCCCC
PANFLGGGALRSSAADMLVFLKANLGIQPGTASPELLSAMQYAQQPFFEVNPNFVMGLGW
CHHHCCCHHHHHHHHHEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCEECCCCEEEECCH
QRVKRERHIVITKNGANQGFSTFIGFSPAKKLGVIVLINQARGKATALGNQILNSLLGL
HHHCCCCEEEEEECCCCCCCHHHHCCCCHHHCCEEEEEECCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9066104 [H]