Click here to switch to the map view.

The map label for this gene is shkA [H]

Identifier: 148360087

GI number: 148360087

Start: 2952323

End: 2953600

Strand: Reverse

Name: shkA [H]

Synonym: LPC_2018

Alternate gene names: 148360087

Gene position: 2953600-2952323 (Counterclockwise)

Preceding gene: 148360086

Following gene: 148360088

Centisome position: 82.58

GC content: 37.25

Gene sequence:

>1278_bases
ATGAGTGATTATGAAGTATTGTTACGCCATCTTGATAGAGAGATACGCGCAAGGAAAGAAGCTGAAGAAATAAGTGAAAA
AAAAATATCCGAGTTATACCGTTTTGCCCAACGTCTGGAAGAGAGTTTAAAGGCTCAAAAAGAAATAAGTAAAAAATTAA
AAGAGAAGACCAAGGCATTAAAGCAGCAAATTGCTAAAACAGAAGAAGAACGGCATGCCAAAAGTACTTTACAAACCATA
TTGGAAAGCGCAATTGAATATTCAATCATCGCAATCAATTTGAAAGGAGTCATCTTGGTTTGGAATGAAGGGGCCAGACG
AAATTACGGCTACGAGGCTCAAGAATTAGTGAACAGAGAGAGCATTGAGATTTTGCATACAGTGGAAGATATCCAGTCAG
GTAAAGTAAGAAAGTTTTTTCAAACAGTACGTCGGGAAGGAAAGGCAGAAGAAATATTTCAAAGAGTCAGAAAAGATGGG
TCCCAGTTCACTGCTTCCGTTACTATGACTATCCACCATGATTCGCAAGGAAAAAAAGTAGGGTACGTCATTATTTCAAA
AGATATTACAGAAATTAAAGAATTTGAAGAAAAGCTGATTAAAAGTAACCAGGATCTTGAGGAGTTTTCATACATTATTT
CCCATGACCTAAAAGCGCCGCTAAGGGCAATTATTCAATTGGCAACATGGATTGAAGAGGATTGCGGAAATAAGTTGGAT
TCTCTTTCCAGAAAAAATCTTCAATTGCTCAGAGAACGTACCCGTCGCATGAGCGGGATGGTAGATGGCTTATTACAATA
TGCGCGGGCAGGCAGAGTCAATATGGAGGTAGAATGGGTAGATACCAAGGAGTTAATTCAAGAAATAATAGATATTCTTA
ACCATGATGAACAATTTACTATTATAGTCCATGAATCCATGCCCCAACTGCCAACGGCCAAATTACTTCTAAGTCAGGTT
TTTTCTAATCTGATAGCAAATAGCATGAAACACCATCATTGTAAAACGGGAACAATTGAAATTGGTGTTTTGGATAAAGG
CACATTTTATGAGTTTTTTGTGGCAGATGATGGTCCGGGTATTGAGCCAGTATATTTTGAGAAAATATTCAGAATATTTC
AAACCTTAAAATCCAAAGATGAGGCAGAAACTACCGGCATAGGATTAACTATAGTAAAGAAAATTGTAGAATCTCAAAAT
GGGAAAATTGAGGTGGACTCTGAGTTGGGTAAAGGCGCAAGATTTTCATTTACATGGCCTAAAGTCCCTCATCAATAA

Upstream 100 bases:

>100_bases
TGTATTAAATATCATAAAGAAAACATGACTATTGCTCGTGAAAATCTGCCTGCAAAAACAGGCTTTAAGGTAAGATTTGT
ATTAACAAAAGGCGATCCTG

Downstream 100 bases:

>100_bases
AGGTTTAGGTCTATAATTAATTTAGAAATAAAAAAATAAAACATTGTCTCACGGAGAATAGTGATGGACCTCGCAGCTGA
TAAAGTAGATATCCTGTATT

Product: sensory box histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 425; Mature: 424

Protein sequence:

>425_residues
MSDYEVLLRHLDREIRARKEAEEISEKKISELYRFAQRLEESLKAQKEISKKLKEKTKALKQQIAKTEEERHAKSTLQTI
LESAIEYSIIAINLKGVILVWNEGARRNYGYEAQELVNRESIEILHTVEDIQSGKVRKFFQTVRREGKAEEIFQRVRKDG
SQFTASVTMTIHHDSQGKKVGYVIISKDITEIKEFEEKLIKSNQDLEEFSYIISHDLKAPLRAIIQLATWIEEDCGNKLD
SLSRKNLQLLRERTRRMSGMVDGLLQYARAGRVNMEVEWVDTKELIQEIIDILNHDEQFTIIVHESMPQLPTAKLLLSQV
FSNLIANSMKHHHCKTGTIEIGVLDKGTFYEFFVADDGPGIEPVYFEKIFRIFQTLKSKDEAETTGIGLTIVKKIVESQN
GKIEVDSELGKGARFSFTWPKVPHQ

Sequences:

>Translated_425_residues
MSDYEVLLRHLDREIRARKEAEEISEKKISELYRFAQRLEESLKAQKEISKKLKEKTKALKQQIAKTEEERHAKSTLQTI
LESAIEYSIIAINLKGVILVWNEGARRNYGYEAQELVNRESIEILHTVEDIQSGKVRKFFQTVRREGKAEEIFQRVRKDG
SQFTASVTMTIHHDSQGKKVGYVIISKDITEIKEFEEKLIKSNQDLEEFSYIISHDLKAPLRAIIQLATWIEEDCGNKLD
SLSRKNLQLLRERTRRMSGMVDGLLQYARAGRVNMEVEWVDTKELIQEIIDILNHDEQFTIIVHESMPQLPTAKLLLSQV
FSNLIANSMKHHHCKTGTIEIGVLDKGTFYEFFVADDGPGIEPVYFEKIFRIFQTLKSKDEAETTGIGLTIVKKIVESQN
GKIEVDSELGKGARFSFTWPKVPHQ
>Mature_424_residues
SDYEVLLRHLDREIRARKEAEEISEKKISELYRFAQRLEESLKAQKEISKKLKEKTKALKQQIAKTEEERHAKSTLQTIL
ESAIEYSIIAINLKGVILVWNEGARRNYGYEAQELVNRESIEILHTVEDIQSGKVRKFFQTVRREGKAEEIFQRVRKDGS
QFTASVTMTIHHDSQGKKVGYVIISKDITEIKEFEEKLIKSNQDLEEFSYIISHDLKAPLRAIIQLATWIEEDCGNKLDS
LSRKNLQLLRERTRRMSGMVDGLLQYARAGRVNMEVEWVDTKELIQEIIDILNHDEQFTIIVHESMPQLPTAKLLLSQVF
SNLIANSMKHHHCKTGTIEIGVLDKGTFYEFFVADDGPGIEPVYFEKIFRIFQTLKSKDEAETTGIGLTIVKKIVESQNG
KIEVDSELGKGARFSFTWPKVPHQ

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=272, Percent_Identity=26.1029411764706, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1787894, Length=222, Percent_Identity=31.981981981982, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1790436, Length=232, Percent_Identity=26.7241379310345, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1786600, Length=249, Percent_Identity=27.3092369477912, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1788549, Length=401, Percent_Identity=22.4438902743142, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786912, Length=217, Percent_Identity=25.8064516129032, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1790346, Length=217, Percent_Identity=29.4930875576037, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI145693157, Length=252, Percent_Identity=24.6031746031746, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1789808, Length=216, Percent_Identity=25.9259259259259, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 49053; Mature: 48922

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDYEVLLRHLDREIRARKEAEEISEKKISELYRFAQRLEESLKAQKEISKKLKEKTKAL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KQQIAKTEEERHAKSTLQTILESAIEYSIIAINLKGVILVWNEGARRNYGYEAQELVNRE
HHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECEEEEEECCCCCCCCCCCHHHHHCHH
SIEILHTVEDIQSGKVRKFFQTVRREGKAEEIFQRVRKDGSQFTASVTMTIHHDSQGKKV
HHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEEEEEEECCCCCEE
GYVIISKDITEIKEFEEKLIKSNQDLEEFSYIISHDLKAPLRAIIQLATWIEEDCGNKLD
EEEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
SLSRKNLQLLRERTRRMSGMVDGLLQYARAGRVNMEVEWVDTKELIQEIIDILNHDEQFT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHCCCCEEE
IIVHESMPQLPTAKLLLSQVFSNLIANSMKHHHCKTGTIEIGVLDKGTFYEFFVADDGPG
EEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEEECCCCC
IEPVYFEKIFRIFQTLKSKDEAETTGIGLTIVKKIVESQNGKIEVDSELGKGARFSFTWP
CCHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHCCCCCEEECCCCCCCCEEEEECC
KVPHQ
CCCCC
>Mature Secondary Structure 
SDYEVLLRHLDREIRARKEAEEISEKKISELYRFAQRLEESLKAQKEISKKLKEKTKAL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KQQIAKTEEERHAKSTLQTILESAIEYSIIAINLKGVILVWNEGARRNYGYEAQELVNRE
HHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECEEEEEECCCCCCCCCCCHHHHHCHH
SIEILHTVEDIQSGKVRKFFQTVRREGKAEEIFQRVRKDGSQFTASVTMTIHHDSQGKKV
HHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEEEEEEECCCCCEE
GYVIISKDITEIKEFEEKLIKSNQDLEEFSYIISHDLKAPLRAIIQLATWIEEDCGNKLD
EEEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
SLSRKNLQLLRERTRRMSGMVDGLLQYARAGRVNMEVEWVDTKELIQEIIDILNHDEQFT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHCCCCEEE
IIVHESMPQLPTAKLLLSQVFSNLIANSMKHHHCKTGTIEIGVLDKGTFYEFFVADDGPG
EEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEEECCCCC
IEPVYFEKIFRIFQTLKSKDEAETTGIGLTIVKKIVESQNGKIEVDSELGKGARFSFTWP
CCHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHCCCCCEEECCCCCCCCEEEEECC
KVPHQ
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]