Click here to switch to the map view.

The map label for this gene is hss [H]

Identifier: 148360048

GI number: 148360048

Start: 2990100

End: 2991518

Strand: Reverse

Name: hss [H]

Synonym: LPC_1979

Alternate gene names: 148360048

Gene position: 2991518-2990100 (Counterclockwise)

Preceding gene: 148360046

Following gene: 148360050

Centisome position: 83.64

GC content: 39.53

Gene sequence:

>1419_bases
ATGGATAAGAATCATAATACAAAAAAAATTTTGTTTAAAAATCGTTTTGTCTTACTAGGATTTGGTTGCGTTGGTCAGGC
ATTAATGCCTTTAATCTTTGAGAAATTTGATATCAAACCATCGCAAGTGACAATCATTGCCGCTGAAGGGGCAAGGGTCG
AGGTTGCTCAAAAATACGGAGTTTCATTCAAGTTACAACAAATTACTCCCCAAAATTATCTTGAAGTGATTGGTAGTACT
TTGGAAGAAAACGATTTTTTAATTGATGTGTCAATCGGCATATCAAGTCTTGCTCTGATTATACTATGTAATCAAAAAGG
AGCATTGTATATTAATGCTGCAACTGAGCCGTGGAAAGAAGAATTTGTTATGGAGAAGATGGCGCTTAATCGCCGAACCA
ATTATTCTTTGCGTGAAGAAGTCCTTCGCTTAAAGGATAAAACTCAAAAAACAGCCTTAATTACTCACGGGGCTAATCCG
GGTCTCGTTTCACATTTTATTAAAGAGGCCTTGTTGAATATTGCAAAGGATAATGGCCTTACCATTAACAGGCCTCAAAA
TGCAGCAGAATGGGCTAATCTTGCCATGACTTTGGGAATTAAAGTAATCCATGTTGCAGAGCAAGACTCTCAAGTTACCT
ATCCTCCAAAATCACCAGGCGAATTCGTTAATACCTGGTCCGCTAATGGTCTGATTTTGGAAGGACTGCAACCTGCTGAA
ATCGGGTGGGGGACACATGAAGCTCATTGGCCCCATGACGCTTATTCTCATAGTAATGGACCACAATGCGCGATCTATCT
GTCTCGCCCCAGTGCCGGTGTAATGGTGCGTTCATGGACGCCAACACTGGGTGCTTTTCACGGTTTTTTAATTACTCATG
CAGAAACTATTTCACTTACCAATTTTTTAACATTAAAAAATGGATCTGAATTATTGTATAGGCCAACAGTTCACTATGCC
TATAATCCTTGTCCAGATGCCAGGCTCTCCATTTTCGAATTAAAAAGTAATGAATGGAAACCACAAAACAAGAATCGCCT
GATTTTAAACGAAATCATTGATGGATGTGATGAATTGGGTGTTTTGTTGATGGGTAATCAAAGAGGGGCGTATTGGTATG
GTTCAACCCTTTCTATCCAGGAAGCAAGGCAAATTGCCCCCTATAATAACGCAACCAGTTTACAAGTTGTCGCCAGTATG
ATTTCAGGAATAATCTGGGCAATAGAGCATCCTGATGAGGGTATCGTAGAACCAGAGGAAGTTGATCACCAATATATTAT
TGATATTGCCAAACCGTATCTTGGAAAAGTCGGCGGCTATTACACGGATTGGACCCCCTTAAAAAATAGAGGGGAACTTT
ATCCTGAAGAAGTGGACTTATCTGATCCATGGCAATTTTTCAATATAAGGGTTAATTAA

Upstream 100 bases:

>100_bases
ATATGAAAGTTATTGATGTCTGTTGGGTATGATCATTGTTGAATAGTTGTTGAGTATTAAAAATTCAAATTAAACTGGGC
CGGGAAGTTAAGGATTCATC

Downstream 100 bases:

>100_bases
AAGGAGTAACGCACTGTAATAATAATTATTATTATTAATCAATGAATTACACATTATCATACCAGTCCAATCAATTGGAC
TGGGGATTCAGTGGCATTGA

Product: homospermidine synthase

Products: NA

Alternate protein names: HSS [H]

Number of amino acids: Translated: 472; Mature: 472

Protein sequence:

>472_residues
MDKNHNTKKILFKNRFVLLGFGCVGQALMPLIFEKFDIKPSQVTIIAAEGARVEVAQKYGVSFKLQQITPQNYLEVIGST
LEENDFLIDVSIGISSLALIILCNQKGALYINAATEPWKEEFVMEKMALNRRTNYSLREEVLRLKDKTQKTALITHGANP
GLVSHFIKEALLNIAKDNGLTINRPQNAAEWANLAMTLGIKVIHVAEQDSQVTYPPKSPGEFVNTWSANGLILEGLQPAE
IGWGTHEAHWPHDAYSHSNGPQCAIYLSRPSAGVMVRSWTPTLGAFHGFLITHAETISLTNFLTLKNGSELLYRPTVHYA
YNPCPDARLSIFELKSNEWKPQNKNRLILNEIIDGCDELGVLLMGNQRGAYWYGSTLSIQEARQIAPYNNATSLQVVASM
ISGIIWAIEHPDEGIVEPEEVDHQYIIDIAKPYLGKVGGYYTDWTPLKNRGELYPEEVDLSDPWQFFNIRVN

Sequences:

>Translated_472_residues
MDKNHNTKKILFKNRFVLLGFGCVGQALMPLIFEKFDIKPSQVTIIAAEGARVEVAQKYGVSFKLQQITPQNYLEVIGST
LEENDFLIDVSIGISSLALIILCNQKGALYINAATEPWKEEFVMEKMALNRRTNYSLREEVLRLKDKTQKTALITHGANP
GLVSHFIKEALLNIAKDNGLTINRPQNAAEWANLAMTLGIKVIHVAEQDSQVTYPPKSPGEFVNTWSANGLILEGLQPAE
IGWGTHEAHWPHDAYSHSNGPQCAIYLSRPSAGVMVRSWTPTLGAFHGFLITHAETISLTNFLTLKNGSELLYRPTVHYA
YNPCPDARLSIFELKSNEWKPQNKNRLILNEIIDGCDELGVLLMGNQRGAYWYGSTLSIQEARQIAPYNNATSLQVVASM
ISGIIWAIEHPDEGIVEPEEVDHQYIIDIAKPYLGKVGGYYTDWTPLKNRGELYPEEVDLSDPWQFFNIRVN
>Mature_472_residues
MDKNHNTKKILFKNRFVLLGFGCVGQALMPLIFEKFDIKPSQVTIIAAEGARVEVAQKYGVSFKLQQITPQNYLEVIGST
LEENDFLIDVSIGISSLALIILCNQKGALYINAATEPWKEEFVMEKMALNRRTNYSLREEVLRLKDKTQKTALITHGANP
GLVSHFIKEALLNIAKDNGLTINRPQNAAEWANLAMTLGIKVIHVAEQDSQVTYPPKSPGEFVNTWSANGLILEGLQPAE
IGWGTHEAHWPHDAYSHSNGPQCAIYLSRPSAGVMVRSWTPTLGAFHGFLITHAETISLTNFLTLKNGSELLYRPTVHYA
YNPCPDARLSIFELKSNEWKPQNKNRLILNEIIDGCDELGVLLMGNQRGAYWYGSTLSIQEARQIAPYNNATSLQVVASM
ISGIIWAIEHPDEGIVEPEEVDHQYIIDIAKPYLGKVGGYYTDWTPLKNRGELYPEEVDLSDPWQFFNIRVN

Specific function: Involved in the NAD(+)-dependent synthesis of the polyamine homospermidine from putrescine [H]

COG id: COG5310

COG function: function code Q; Homospermidine synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023181
- InterPro:   IPR016040
- InterPro:   IPR005097 [H]

Pfam domain/function: PF03435 Saccharop_dh [H]

EC number: =2.5.1.44 [H]

Molecular weight: Translated: 52940; Mature: 52940

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKNHNTKKILFKNRFVLLGFGCVGQALMPLIFEKFDIKPSQVTIIAAEGARVEVAQKYG
CCCCCCCEEEEEECCEEEEECCHHHHHHHHHHHHHCCCCCCEEEEEEECCCEEEEEHHCC
VSFKLQQITPQNYLEVIGSTLEENDFLIDVSIGISSLALIILCNQKGALYINAATEPWKE
CEEEEECCCHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEEEECCCCEEEEECCCCCHHH
EFVMEKMALNRRTNYSLREEVLRLKDKTQKTALITHGANPGLVSHFIKEALLNIAKDNGL
HHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCE
TINRPQNAAEWANLAMTLGIKVIHVAEQDSQVTYPPKSPGEFVNTWSANGLILEGLQPAE
EEECCCCHHHHHHHHEEECEEEEEEECCCCEEECCCCCCCCHHCCCCCCCEEEECCCCCC
IGWGTHEAHWPHDAYSHSNGPQCAIYLSRPSAGVMVRSWTPTLGAFHGFLITHAETISLT
CCCCCCCCCCCCHHCCCCCCCEEEEEEECCCCCEEEEECCCCHHHHHHHHEEEEEEEEEE
NFLTLKNGSELLYRPTVHYAYNPCPDARLSIFELKSNEWKPQNKNRLILNEIIDGCDELG
EEEEECCCCCEEEECEEEEECCCCCCCCEEEEEECCCCCCCCCCCEEEHHHHHCCHHHCC
VLLMGNQRGAYWYGSTLSIQEARQIAPYNNATSLQVVASMISGIIWAIEHPDEGIVEPEE
EEEECCCCCCEEECCEEEHHHHHHCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCCHHH
VDHQYIIDIAKPYLGKVGGYYTDWTPLKNRGELYPEEVDLSDPWQFFNIRVN
CCCEEEEEHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEC
>Mature Secondary Structure
MDKNHNTKKILFKNRFVLLGFGCVGQALMPLIFEKFDIKPSQVTIIAAEGARVEVAQKYG
CCCCCCCEEEEEECCEEEEECCHHHHHHHHHHHHHCCCCCCEEEEEEECCCEEEEEHHCC
VSFKLQQITPQNYLEVIGSTLEENDFLIDVSIGISSLALIILCNQKGALYINAATEPWKE
CEEEEECCCHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEEEECCCCEEEEECCCCCHHH
EFVMEKMALNRRTNYSLREEVLRLKDKTQKTALITHGANPGLVSHFIKEALLNIAKDNGL
HHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCE
TINRPQNAAEWANLAMTLGIKVIHVAEQDSQVTYPPKSPGEFVNTWSANGLILEGLQPAE
EEECCCCHHHHHHHHEEECEEEEEEECCCCEEECCCCCCCCHHCCCCCCCEEEECCCCCC
IGWGTHEAHWPHDAYSHSNGPQCAIYLSRPSAGVMVRSWTPTLGAFHGFLITHAETISLT
CCCCCCCCCCCCHHCCCCCCCEEEEEEECCCCCEEEEECCCCHHHHHHHHEEEEEEEEEE
NFLTLKNGSELLYRPTVHYAYNPCPDARLSIFELKSNEWKPQNKNRLILNEIIDGCDELG
EEEEECCCCCEEEECEEEEECCCCCCCCEEEEEECCCCCCCCCCCEEEHHHHHCCHHHCC
VLLMGNQRGAYWYGSTLSIQEARQIAPYNNATSLQVVASMISGIIWAIEHPDEGIVEPEE
EEEECCCCCCEEECCEEEHHHHHHCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCCHHH
VDHQYIIDIAKPYLGKVGGYYTDWTPLKNRGELYPEEVDLSDPWQFFNIRVN
CCCEEEEEHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]