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The map label for this gene is hemN [H]

Identifier: 148359895

GI number: 148359895

Start: 2771752

End: 2772879

Strand: Direct

Name: hemN [H]

Synonym: LPC_1823

Alternate gene names: 148359895

Gene position: 2771752-2772879 (Clockwise)

Preceding gene: 148359892

Following gene: 148359897

Centisome position: 77.5

GC content: 39.36

Gene sequence:

>1128_bases
ATGCTTCCGTTATCCTTGTACATTCATATTCCCTGGTGCATCAGAAAATGCCCATACTGTGATTTTAACTCACACAAAAG
CCCTGATGTTTTACCCGAACACCAGTATGTTCAGGCTTTGATTGAAGACCTTAAAACGGATATTTCCTCATACAATACCC
GTGAAATTAACTCCATTTTTATTGGTGGCGGCACACCCAGTTTATTTTCAGCCGAAGCTTATAACAACTTATTTAATGAA
TTAAAGCGCATGCTCTCCTTTGCAAAAAATATTGAAATCACAATGGAAGCCAATCCCGGTACTGTAGAACAACATCGATT
TACTGATTATAGACAATCAGGAATCAATCGTCTTTCTTTGGGAATTCAAAGCTTTAATCCCAATCACTTAAAAATTCTTG
GCCGTATTCATGACGAGAAACAAGCCCATTCTGCAATAGATACTGCCCGTAAAGCCGGCTTTGATAATCTCAATCTTGAT
ATCATGCACAGTTTACCTAATCAAAGTGTAACGCAGGGATTACAGGATCTTAAGACCGCTTTATCCTATCAACCTGAGCA
TTTATCCTGGTATCAATTAACCATAGAACCGAATACTGTATTTTACAAGCATACTCCTCCCCTGCCTTCCGAAGAAGAAG
ATTACTTGCTGGAGGAGCAAGGATTTGCCCTGTTGCATGATTCCGGATATCACCGCTATGAAATTTCTGCCTTTTCCAAA
CCGGAAAAGCAAGCCAGACACAATATCAATTATTGGCTATTCGGTGATTATTTGGGTATAGGCGCTGGTGCTCATGGAAA
AATGACAACCCCAAACGCAATAATAAGAACCCGTAAGCACCGTCAACCCAAAGATTATCTGGATAATGAGAAACCTTATC
TGGCTGCTCGAGAAACCATTACAGGTAAAGAATTGTTGTTTGAGTTTATGCTGAATACAACCCGGCTGGAACAATCCATA
CCTTTGGAGTTATTTACGACAGCGACAGGATTGGAACTTAATCAGCTTTTACCCTTGCTGAAATTGGCTAATAAGAAACA
ATTGATTAATTTAACAGATACTGATTGGCAAGTAACACCATTAGGCAGGCAATATACTAATGATTTGCAAGCCTTGTTTC
TTCCCTAA

Upstream 100 bases:

>100_bases
ATTTTGGTTTATTTCGCATCAATGGTCATCACTTAATTTTGTAGCAAAATTGCTACCATGATACTATTGCATTCCCTAAC
AAGCCAGTTTAAAAATTGTA

Downstream 100 bases:

>100_bases
TTCGCTGTTTCAAAAATTATTGATTCTTGCTTCATTGCAGAGAGTGGATTAGAGAAGGGGGTTTATATCCCCCCATTAAT
TGCTCAAGGCGTTCTGCAAC

Product: oxygen-independent coproporphyrinogen III oxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MLPLSLYIHIPWCIRKCPYCDFNSHKSPDVLPEHQYVQALIEDLKTDISSYNTREINSIFIGGGTPSLFSAEAYNNLFNE
LKRMLSFAKNIEITMEANPGTVEQHRFTDYRQSGINRLSLGIQSFNPNHLKILGRIHDEKQAHSAIDTARKAGFDNLNLD
IMHSLPNQSVTQGLQDLKTALSYQPEHLSWYQLTIEPNTVFYKHTPPLPSEEEDYLLEEQGFALLHDSGYHRYEISAFSK
PEKQARHNINYWLFGDYLGIGAGAHGKMTTPNAIIRTRKHRQPKDYLDNEKPYLAARETITGKELLFEFMLNTTRLEQSI
PLELFTTATGLELNQLLPLLKLANKKQLINLTDTDWQVTPLGRQYTNDLQALFLP

Sequences:

>Translated_375_residues
MLPLSLYIHIPWCIRKCPYCDFNSHKSPDVLPEHQYVQALIEDLKTDISSYNTREINSIFIGGGTPSLFSAEAYNNLFNE
LKRMLSFAKNIEITMEANPGTVEQHRFTDYRQSGINRLSLGIQSFNPNHLKILGRIHDEKQAHSAIDTARKAGFDNLNLD
IMHSLPNQSVTQGLQDLKTALSYQPEHLSWYQLTIEPNTVFYKHTPPLPSEEEDYLLEEQGFALLHDSGYHRYEISAFSK
PEKQARHNINYWLFGDYLGIGAGAHGKMTTPNAIIRTRKHRQPKDYLDNEKPYLAARETITGKELLFEFMLNTTRLEQSI
PLELFTTATGLELNQLLPLLKLANKKQLINLTDTDWQVTPLGRQYTNDLQALFLP
>Mature_375_residues
MLPLSLYIHIPWCIRKCPYCDFNSHKSPDVLPEHQYVQALIEDLKTDISSYNTREINSIFIGGGTPSLFSAEAYNNLFNE
LKRMLSFAKNIEITMEANPGTVEQHRFTDYRQSGINRLSLGIQSFNPNHLKILGRIHDEKQAHSAIDTARKAGFDNLNLD
IMHSLPNQSVTQGLQDLKTALSYQPEHLSWYQLTIEPNTVFYKHTPPLPSEEEDYLLEEQGFALLHDSGYHRYEISAFSK
PEKQARHNINYWLFGDYLGIGAGAHGKMTTPNAIIRTRKHRQPKDYLDNEKPYLAARETITGKELLFEFMLNTTRLEQSI
PLELFTTATGLELNQLLPLLKLANKKQLINLTDTDWQVTPLGRQYTNDLQALFLP

Specific function: Unknown

COG id: COG0635

COG function: function code H; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anaerobic coproporphyrinogen-III oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922911, Length=281, Percent_Identity=33.4519572953737, Blast_Score=186, Evalue=2e-47,
Organism=Escherichia coli, GI1789325, Length=373, Percent_Identity=47.1849865951743, Blast_Score=359, Evalue=1e-100,
Organism=Escherichia coli, GI87082341, Length=395, Percent_Identity=25.3164556962025, Blast_Score=121, Evalue=6e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR004559
- InterPro:   IPR010723
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06969 HemN_C; PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 43048; Mature: 43048

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPLSLYIHIPWCIRKCPYCDFNSHKSPDVLPEHQYVQALIEDLKTDISSYNTREINSIF
CCCEEEEEECCHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEE
IGGGTPSLFSAEAYNNLFNELKRMLSFAKNIEITMEANPGTVEQHRFTDYRQSGINRLSL
ECCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHCCCCEEEE
GIQSFNPNHLKILGRIHDEKQAHSAIDTARKAGFDNLNLDIMHSLPNQSVTQGLQDLKTA
EHCCCCCCEEEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHHHHHHH
LSYQPEHLSWYQLTIEPNTVFYKHTPPLPSEEEDYLLEEQGFALLHDSGYHRYEISAFSK
HCCCCCCCEEEEEEECCCEEEEECCCCCCCCCCCCEECCCCEEEEECCCCCEEEECCCCC
PEKQARHNINYWLFGDYLGIGAGAHGKMTTPNAIIRTRKHRQPKDYLDNEKPYLAARETI
CHHHHHCCCCEEEEECEEEECCCCCCCCCCCHHHHHHHHCCCCHHHCCCCCCCEEEHHCC
TGKELLFEFMLNTTRLEQSIPLELFTTATGLELNQLLPLLKLANKKQLINLTDTDWQVTP
CHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHCCCCEEEEECCCCEEEEE
LGRQYTNDLQALFLP
CCHHHHCCCCEEECC
>Mature Secondary Structure
MLPLSLYIHIPWCIRKCPYCDFNSHKSPDVLPEHQYVQALIEDLKTDISSYNTREINSIF
CCCEEEEEECCHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEE
IGGGTPSLFSAEAYNNLFNELKRMLSFAKNIEITMEANPGTVEQHRFTDYRQSGINRLSL
ECCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHCCCCEEEE
GIQSFNPNHLKILGRIHDEKQAHSAIDTARKAGFDNLNLDIMHSLPNQSVTQGLQDLKTA
EHCCCCCCEEEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHHHHHHH
LSYQPEHLSWYQLTIEPNTVFYKHTPPLPSEEEDYLLEEQGFALLHDSGYHRYEISAFSK
HCCCCCCCEEEEEEECCCEEEEECCCCCCCCCCCCEECCCCEEEEECCCCCEEEECCCCC
PEKQARHNINYWLFGDYLGIGAGAHGKMTTPNAIIRTRKHRQPKDYLDNEKPYLAARETI
CHHHHHCCCCEEEEECEEEECCCCCCCCCCCHHHHHHHHCCCCHHHCCCCCCCEEEHHCC
TGKELLFEFMLNTTRLEQSIPLELFTTATGLELNQLLPLLKLANKKQLINLTDTDWQVTP
CHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHCCCCEEEEECCCCEEEEE
LGRQYTNDLQALFLP
CCHHHHCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]