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The map label for this gene is yaeL [C]

Identifier: 148359872

GI number: 148359872

Start: 2749898

End: 2750971

Strand: Reverse

Name: yaeL [C]

Synonym: LPC_1800

Alternate gene names: 148359872

Gene position: 2750971-2749898 (Counterclockwise)

Preceding gene: 148359873

Following gene: 148359870

Centisome position: 76.92

GC content: 38.45

Gene sequence:

>1074_bases
ATGATTATGGCATTGGTAGCCATAATACTTACGTTAATCCTGGTGATAGGTATACATGAACTGGGGCATGCACTGGCAGC
CCGCCTGTTTCAAGTCAAAATTAGTAAAATTTCCATAGGATTTGGAAAACCATTAATTCAATGGCAAACCCAAAGTGGTT
GTAACTGGATCTGGGCAATGTGGCCTTTGGGAGGGTATGTTCAATTACTGAATTCGAGGATTAGTCCAGTAAAGCCACAA
GAAAATGCTTATTGTTTTGATAAGAAACCAATTTGGATTCGTGTGCTGATTTTATTGTCAGGAGCGATTGCCAACCTTAT
TACCGCATGGATAGCCTTGGTGTTGGTTTTTTATATTGGCATTAGCTACAAACAACCTCAAATTCAATCGGTAAAACTGG
ATAGCCTTGCTGCCAAGGCAGGTATTCAAGCAGGCGACCAATGGGTTTCTGTAGAGAATTACCCAACTGATTCCTGGCAA
GGGGTAGGTATGCAATTGGTAATTCATTGGGGGCAAAAGAATGTTCAAATTGTTTTAAGGCAAGCGAATCAACAATTAAA
ACAATTGAGTCTTGATTTAAGTCAGATTGAATTTACTTCAAAAGATGGCTCTTTGCTCGAGAGTCTGGGGATCAAGCCTG
ACTTGTCAGCAGTTTCCAGTTTGACGCGCTATCCATCTCTACTGGCTTCAATGCAAAAAGCGTTTGCTGAGATAATCCAT
ACTATGTACTTTTTTATAATGATATTGAAGCAATTGTTTCTCGGGGTTATTCCTTTTTCAATTTTACTTGGACCGTTGGC
TATTTTTTCTGTTTCTGTGGCTTCTTTAACTCAAGGTGTTATCGTTTTTTTACTATTCATTGCTACATTGAGTCTTGCTG
TAGCTTTGGTCAATTTATTTCCTATACCTGGTCTTGATGGAGGCAGCATTTTATATTCGGTTATAGAGAAAATTCGTGGG
AAACCTGTCTCAGTGGCTGTGGAAGTCTTGCTTCATCGCTTGATGATTATTCTATTTTGTGTTTTGTTAGTGCATTTATT
AATGAATGATTTGAATCGATATTTACACCATTGA

Upstream 100 bases:

>100_bases
GGATTCCAATGTTGCAGCTGGTAGTTGATAATACGCATAAATAGATTATTCTTTCTGGTGCTTTTTTAATAAGCCTCATA
TTCTGGATAAGGAGTCCATT

Downstream 100 bases:

>100_bases
CAGTGGACTCATAGGTACGGGCTGCCTTTTAATTTTTAGTTACAGCCCGCGCACAACAACATATATCTACTCTCTTAACT
CCGGCATTTTTTAATGTATG

Product: membrane associated zinc metalloprotease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MIMALVAIILTLILVIGIHELGHALAARLFQVKISKISIGFGKPLIQWQTQSGCNWIWAMWPLGGYVQLLNSRISPVKPQ
ENAYCFDKKPIWIRVLILLSGAIANLITAWIALVLVFYIGISYKQPQIQSVKLDSLAAKAGIQAGDQWVSVENYPTDSWQ
GVGMQLVIHWGQKNVQIVLRQANQQLKQLSLDLSQIEFTSKDGSLLESLGIKPDLSAVSSLTRYPSLLASMQKAFAEIIH
TMYFFIMILKQLFLGVIPFSILLGPLAIFSVSVASLTQGVIVFLLFIATLSLAVALVNLFPIPGLDGGSILYSVIEKIRG
KPVSVAVEVLLHRLMIILFCVLLVHLLMNDLNRYLHH

Sequences:

>Translated_357_residues
MIMALVAIILTLILVIGIHELGHALAARLFQVKISKISIGFGKPLIQWQTQSGCNWIWAMWPLGGYVQLLNSRISPVKPQ
ENAYCFDKKPIWIRVLILLSGAIANLITAWIALVLVFYIGISYKQPQIQSVKLDSLAAKAGIQAGDQWVSVENYPTDSWQ
GVGMQLVIHWGQKNVQIVLRQANQQLKQLSLDLSQIEFTSKDGSLLESLGIKPDLSAVSSLTRYPSLLASMQKAFAEIIH
TMYFFIMILKQLFLGVIPFSILLGPLAIFSVSVASLTQGVIVFLLFIATLSLAVALVNLFPIPGLDGGSILYSVIEKIRG
KPVSVAVEVLLHRLMIILFCVLLVHLLMNDLNRYLHH
>Mature_357_residues
MIMALVAIILTLILVIGIHELGHALAARLFQVKISKISIGFGKPLIQWQTQSGCNWIWAMWPLGGYVQLLNSRISPVKPQ
ENAYCFDKKPIWIRVLILLSGAIANLITAWIALVLVFYIGISYKQPQIQSVKLDSLAAKAGIQAGDQWVSVENYPTDSWQ
GVGMQLVIHWGQKNVQIVLRQANQQLKQLSLDLSQIEFTSKDGSLLESLGIKPDLSAVSSLTRYPSLLASMQKAFAEIIH
TMYFFIMILKQLFLGVIPFSILLGPLAIFSVSVASLTQGVIVFLLFIATLSLAVALVNLFPIPGLDGGSILYSVIEKIRG
KPVSVAVEVLLHRLMIILFCVLLVHLLMNDLNRYLHH

Specific function: Unknown

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1786373, Length=210, Percent_Identity=34.2857142857143, Blast_Score=128, Evalue=5e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR004387
- InterPro:   IPR008915 [H]

Pfam domain/function: PF00595 PDZ; PF02163 Peptidase_M50 [H]

EC number: NA

Molecular weight: Translated: 39562; Mature: 39562

Theoretical pI: Translated: 9.76; Mature: 9.76

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIMALVAIILTLILVIGIHELGHALAARLFQVKISKISIGFGKPLIQWQTQSGCNWIWAM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCEEEECCCCCCEEEEC
WPLGGYVQLLNSRISPVKPQENAYCFDKKPIWIRVLILLSGAIANLITAWIALVLVFYIG
CCCHHHHHHHHCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ISYKQPQIQSVKLDSLAAKAGIQAGDQWVSVENYPTDSWQGVGMQLVIHWGQKNVQIVLR
CCCCCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCEEEEEEECCCCHHHHHH
QANQQLKQLSLDLSQIEFTSKDGSLLESLGIKPDLSAVSSLTRYPSLLASMQKAFAEIIH
HHHHHHHHHHHHHHHHEECCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TMYFFIMILKQLFLGVIPFSILLGPLAIFSVSVASLTQGVIVFLLFIATLSLAVALVNLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PIPGLDGGSILYSVIEKIRGKPVSVAVEVLLHRLMIILFCVLLVHLLMNDLNRYLHH
CCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIMALVAIILTLILVIGIHELGHALAARLFQVKISKISIGFGKPLIQWQTQSGCNWIWAM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCEEEECCCCCCEEEEC
WPLGGYVQLLNSRISPVKPQENAYCFDKKPIWIRVLILLSGAIANLITAWIALVLVFYIG
CCCHHHHHHHHCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ISYKQPQIQSVKLDSLAAKAGIQAGDQWVSVENYPTDSWQGVGMQLVIHWGQKNVQIVLR
CCCCCCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCEEEEEEECCCCHHHHHH
QANQQLKQLSLDLSQIEFTSKDGSLLESLGIKPDLSAVSSLTRYPSLLASMQKAFAEIIH
HHHHHHHHHHHHHHHHEECCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TMYFFIMILKQLFLGVIPFSILLGPLAIFSVSVASLTQGVIVFLLFIATLSLAVALVNLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PIPGLDGGSILYSVIEKIRGKPVSVAVEVLLHRLMIILFCVLLVHLLMNDLNRYLHH
CCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]