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The map label for this gene is comF [H]

Identifier: 148359871

GI number: 148359871

Start: 2749279

End: 2749869

Strand: Direct

Name: comF [H]

Synonym: LPC_1799

Alternate gene names: 148359871

Gene position: 2749279-2749869 (Clockwise)

Preceding gene: 148359869

Following gene: 148359874

Centisome position: 76.87

GC content: 38.58

Gene sequence:

>591_bases
ATGAAACAACTTGGATCTTGCTGTCAGTACTGTGCCTACCCCCTTTCTGATGATACGTATCTGGTTTGTGGTCAATGCGT
TAGAAAAAGGCCCTCCTTTGATAGGGCTTATATAGCGTATCGTTTTGAAGAACCTCTGCGTAATTTAATACATCAGTTTA
AATACCATAATGGCCTTTATCTGGCCTCGTTTCTAAAGCAATTACTTCTTGATGCCTTACCCAAAAGCGCATTGAAACCA
GATTGCCTAATTCCCGTTCCCATGCATCCCAAACGATTAAAACGAAGGGGATTTAACCAGGCTGCTGTATTAACCAGATT
ATTAGCTCGTCAATTAAAAATCCCTTATGATTTATATTATTGCCAAAAAATAATCAATACCGCTTCACAAGCCAACCTTG
ATGGAGAGCAACGAAGGAAAAATTTACGTCATGCATTTTATGTATCACCTGTAACTTATGAACACGTCATGATTGTTGAT
GACTTATTAACCACAGGCAGCACAGCCAATGAAATGGCACATACATTAAAAAATGCCGGAGTTAAGAGAGTAGATATATG
TTGTTGTGCGCGGGCTGTAACTAAAAATTAA

Upstream 100 bases:

>100_bases
CTTAAGTATAACACAGAACTTACGTTTACCTTCAATATGCACTCTTTGCAACCAGTTTCACAAAAGCCAACTTGCAGTTT
GCTCTAATTGCATAGAGTTT

Downstream 100 bases:

>100_bases
AAGGCAGCCCGTACCTATGAGTCCACTGTCAATGGTGTAAATATCGATTCAAATCATTCATTAATAAATGCACTAACAAA
ACACAAAATAGAATAATCAT

Product: competence protein ComF

Products: NA

Alternate protein names: DNA transformation protein ComF; Protein COM101A [H]

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MKQLGSCCQYCAYPLSDDTYLVCGQCVRKRPSFDRAYIAYRFEEPLRNLIHQFKYHNGLYLASFLKQLLLDALPKSALKP
DCLIPVPMHPKRLKRRGFNQAAVLTRLLARQLKIPYDLYYCQKIINTASQANLDGEQRRKNLRHAFYVSPVTYEHVMIVD
DLLTTGSTANEMAHTLKNAGVKRVDICCCARAVTKN

Sequences:

>Translated_196_residues
MKQLGSCCQYCAYPLSDDTYLVCGQCVRKRPSFDRAYIAYRFEEPLRNLIHQFKYHNGLYLASFLKQLLLDALPKSALKP
DCLIPVPMHPKRLKRRGFNQAAVLTRLLARQLKIPYDLYYCQKIINTASQANLDGEQRRKNLRHAFYVSPVTYEHVMIVD
DLLTTGSTANEMAHTLKNAGVKRVDICCCARAVTKN
>Mature_196_residues
MKQLGSCCQYCAYPLSDDTYLVCGQCVRKRPSFDRAYIAYRFEEPLRNLIHQFKYHNGLYLASFLKQLLLDALPKSALKP
DCLIPVPMHPKRLKRRGFNQAAVLTRLLARQLKIPYDLYYCQKIINTASQANLDGEQRRKNLRHAFYVSPVTYEHVMIVD
DLLTTGSTANEMAHTLKNAGVKRVDICCCARAVTKN

Specific function: Involved in transformation (competence for DNA uptake) [H]

COG id: COG1040

COG function: function code R; Predicted amidophosphoribosyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ComF/GntX family [H]

Homologues:

Organism=Escherichia coli, GI87082263, Length=192, Percent_Identity=34.375, Blast_Score=101, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005222
- InterPro:   IPR000836 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: NA

Molecular weight: Translated: 22491; Mature: 22491

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
5.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQLGSCCQYCAYPLSDDTYLVCGQCVRKRPSFDRAYIAYRFEEPLRNLIHQFKYHNGLY
CCHHHHHHHHHCCCCCCCCEEHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHH
LASFLKQLLLDALPKSALKPDCLIPVPMHPKRLKRRGFNQAAVLTRLLARQLKIPYDLYY
HHHHHHHHHHHHCCHHHCCCCCEECCCCCHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHH
CQKIINTASQANLDGEQRRKNLRHAFYVSPVTYEHVMIVDDLLTTGSTANEMAHTLKNAG
HHHHHHHHHHCCCCHHHHHHHHHHHEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCC
VKRVDICCCARAVTKN
CCHHHHHHHHHHHHCC
>Mature Secondary Structure
MKQLGSCCQYCAYPLSDDTYLVCGQCVRKRPSFDRAYIAYRFEEPLRNLIHQFKYHNGLY
CCHHHHHHHHHCCCCCCCCEEHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHH
LASFLKQLLLDALPKSALKPDCLIPVPMHPKRLKRRGFNQAAVLTRLLARQLKIPYDLYY
HHHHHHHHHHHHCCHHHCCCCCEECCCCCHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHH
CQKIINTASQANLDGEQRRKNLRHAFYVSPVTYEHVMIVDDLLTTGSTANEMAHTLKNAG
HHHHHHHHHHCCCCHHHHHHHHHHHEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCC
VKRVDICCCARAVTKN
CCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1916268; 1856167; 7542800 [H]