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The map label for this gene is motA [H]

Identifier: 148359857

GI number: 148359857

Start: 2733512

End: 2734417

Strand: Direct

Name: motA [H]

Synonym: LPC_1785

Alternate gene names: 148359857

Gene position: 2733512-2734417 (Clockwise)

Preceding gene: 148359856

Following gene: 148359858

Centisome position: 76.43

GC content: 39.62

Gene sequence:

>906_bases
ATGTTAATTATAGTAGGTTATATTGTAATACTACTCTGTGTATTTGGTGGATTCAGCCTGACAGGCGGCCATCTCGCCGC
TATATTTCAACCCGTTGAATTATTGATAATCGGAGGGGCCGCCATAGGTTCCTTTATCGTCGGTAATAATATTACTGTTT
TAAAATCTGTTCTAAAATCTCTGCCTGCTACATTTCGCGGCCAAAAATCGGCAAAGCAAGCCTCCAGTGATTTGTTAAGC
CTTCTATACCACTTACTCAGTAAAGCAAGGCAACAAGGGTTAATGTCGCTCGAAAATGACATTGACGAGCCGGATAAAAG
CCCAATTTTTACCAGTTATCCCAATTTAATGAGTAATCACCATTTAATAGAGTTTATTTGTGATTATCTGAGATTGATTA
TTACCTCCAACATGCAGCCTTTTCAATTGGAAAGCTTGATGGATATGGAGATCGAATCTCACCATGAAGAAGAAATGATC
CCGGCCAATGCCATCACCAAACTGGCTGATGCCATGCCTGCTTTTGGTATCGTCGCAGCAGTATTAGGTGTTGTCCATAC
CATGGAATCCATCAGCTTACCTCCCTCTGAATTAGGTGTTTTAATCGCTCACGCATTAGTGGGAACCTTTTTAGGTATTT
TAATTGGCTATGGTTTTGTTGGGCCTATCGCTACTGCTATGGAACAAAATGCCAATCAAAATCAATTGATGCTGCAATGT
ATAAAAGTTACCATCCTGGCAAGCTTGCACAATAACCCTCCTATTATTGCTACTGAATTTGGCCGTAAAGTATTATTTAC
ATCGCAAAGACCTTCATTTAATCAATTAAATGATGAAATAAAAAATGCCAAAACCGCTCAGACAACAACTCAAAACTCTG
AAGCAACAGAAGCTACGTCCAGTTAG

Upstream 100 bases:

>100_bases
TCCCAATGACTGAAGGTATAGCACTGTATGACATGTCTGCCAAAGACACTATGAAAAAATATCAAGACTAATTGGACACC
AGATACTATAGGATAGGGAT

Downstream 100 bases:

>100_bases
GTTACAGCCATGAGTGAAATAAATGACATCAGCGATCCGATCAACGACGATCTGGAAAAAAAGGACAAACGGGAAAAAAA
AGAAAAAAACACTCACTATA

Product: flagellar motor protein MotA

Products: NA

Alternate protein names: Chemotaxis protein MotA [H]

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MLIIVGYIVILLCVFGGFSLTGGHLAAIFQPVELLIIGGAAIGSFIVGNNITVLKSVLKSLPATFRGQKSAKQASSDLLS
LLYHLLSKARQQGLMSLENDIDEPDKSPIFTSYPNLMSNHHLIEFICDYLRLIITSNMQPFQLESLMDMEIESHHEEEMI
PANAITKLADAMPAFGIVAAVLGVVHTMESISLPPSELGVLIAHALVGTFLGILIGYGFVGPIATAMEQNANQNQLMLQC
IKVTILASLHNNPPIIATEFGRKVLFTSQRPSFNQLNDEIKNAKTAQTTTQNSEATEATSS

Sequences:

>Translated_301_residues
MLIIVGYIVILLCVFGGFSLTGGHLAAIFQPVELLIIGGAAIGSFIVGNNITVLKSVLKSLPATFRGQKSAKQASSDLLS
LLYHLLSKARQQGLMSLENDIDEPDKSPIFTSYPNLMSNHHLIEFICDYLRLIITSNMQPFQLESLMDMEIESHHEEEMI
PANAITKLADAMPAFGIVAAVLGVVHTMESISLPPSELGVLIAHALVGTFLGILIGYGFVGPIATAMEQNANQNQLMLQC
IKVTILASLHNNPPIIATEFGRKVLFTSQRPSFNQLNDEIKNAKTAQTTTQNSEATEATSS
>Mature_301_residues
MLIIVGYIVILLCVFGGFSLTGGHLAAIFQPVELLIIGGAAIGSFIVGNNITVLKSVLKSLPATFRGQKSAKQASSDLLS
LLYHLLSKARQQGLMSLENDIDEPDKSPIFTSYPNLMSNHHLIEFICDYLRLIITSNMQPFQLESLMDMEIESHHEEEMI
PANAITKLADAMPAFGIVAAVLGVVHTMESISLPPSELGVLIAHALVGTFLGILIGYGFVGPIATAMEQNANQNQLMLQC
IKVTILASLHNNPPIIATEFGRKVLFTSQRPSFNQLNDEIKNAKTAQTTTQNSEATEATSS

Specific function: MotA and MotB comprise the stator element of the flagellar motor complex. Required for rotation of the flagellar motor. Probable transmembrane proton channel. Overexpression of MotA, with or without MotB, restores motility in a yhjH disruption, (a c-di-GM

COG id: COG1291

COG function: function code N; Flagellar motor component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MotA family [H]

Homologues:

Organism=Escherichia coli, GI1788199, Length=295, Percent_Identity=52.5423728813559, Blast_Score=337, Evalue=6e-94,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000540
- InterPro:   IPR022522
- InterPro:   IPR002898 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 32562; Mature: 32562

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: PS01307 MOTA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIIVGYIVILLCVFGGFSLTGGHLAAIFQPVELLIIGGAAIGSFIVGNNITVLKSVLKS
CEEHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHEEECCHHHHHHHHCCCHHHHHHHHHH
LPATFRGQKSAKQASSDLLSLLYHLLSKARQQGLMSLENDIDEPDKSPIFTSYPNLMSNH
CCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCC
HLIEFICDYLRLIITSNMQPFQLESLMDMEIESHHEEEMIPANAITKLADAMPAFGIVAA
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHCCHHHHHHH
VLGVVHTMESISLPPSELGVLIAHALVGTFLGILIGYGFVGPIATAMEQNANQNQLMLQC
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
IKVTILASLHNNPPIIATEFGRKVLFTSQRPSFNQLNDEIKNAKTAQTTTQNSEATEATS
HHHHHHHHHCCCCCEEEECCCCEEEEECCCCCHHHHHHHHHCCHHHHHCCCCCCCHHCCC
S
C
>Mature Secondary Structure
MLIIVGYIVILLCVFGGFSLTGGHLAAIFQPVELLIIGGAAIGSFIVGNNITVLKSVLKS
CEEHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHEEECCHHHHHHHHCCCHHHHHHHHHH
LPATFRGQKSAKQASSDLLSLLYHLLSKARQQGLMSLENDIDEPDKSPIFTSYPNLMSNH
CCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCC
HLIEFICDYLRLIITSNMQPFQLESLMDMEIESHHEEEMIPANAITKLADAMPAFGIVAA
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHCCHHHHHHH
VLGVVHTMESISLPPSELGVLIAHALVGTFLGILIGYGFVGPIATAMEQNANQNQLMLQC
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
IKVTILASLHNNPPIIATEFGRKVLFTSQRPSFNQLNDEIKNAKTAQTTTQNSEATEATS
HHHHHHHHHCCCCCEEEECCCCEEEEECCCCCHHHHHHHHHCCHHHHHCCCCCCCHHCCC
S
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 6090403; 9097040; 9278503; 3007435; 1719217; 7643400 [H]