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The map label for this gene is gpsA [H]

Identifier: 148359846

GI number: 148359846

Start: 2722491

End: 2723480

Strand: Direct

Name: gpsA [H]

Synonym: LPC_1774

Alternate gene names: 148359846

Gene position: 2722491-2723480 (Clockwise)

Preceding gene: 148359845

Following gene: 148359849

Centisome position: 76.12

GC content: 44.34

Gene sequence:

>990_bases
ATGAATAAAAAAACCATTGCCATGTTAGGTGCCGGCTCCTGGGGCACTGCTGTCGCAATTCATCTAGCTAAAATAGGGCA
TAAAACGCTGCTGTGGAGCCATAATCCACAGCATGTTGCCCTCATGGCTGAACAGCATTCAAATCCAGCTTACCTTCCTG
GTATACCTTTTCCAGAGAATTTGATTCCTTCTGATGATTTAATTGAATGCGTTCAATCAGCAGATTATGTCATCATAGCA
GTTCCTTCTCATGCCTTTGCGGAAATAACCAATAAAATCCCTAAACCAACCCAAGGATTGGCGTGGCTTACGAAGGGTGT
TGATCCAGCGAGTCATCAATTATTAAGCCAACTGGTTGCCAGTCGATTTGGAGTTGATTTTCCCATAGCAGTGATTTCAG
GCCCATCCTTTGCCAAAGAAGTGGCTCGCTTCCTGCCTACAGCTCTCACCTTGGCCAGTAACAATACGAATTATCAAAAA
AAAATGCATCAACTATTTCATCACGACAACATTCGTGTCTATTTAAGTGATGATTTAATAGGTGTGCAATTATGTGGCGC
TGTTAAAAATATCCTGGCGATAGCCTGTGGAATCAGTGATGGCTTAGGCTATGGTGCTAATGCCAAAGCAGCGCTTATTA
CCCGTGGACTTGCTGAAATGACTCGTCTGGGATTAAGCATGGGAGCACGGCAAGATACTTTTCTAGGCTTGGCTGGTGTA
GGGGATCTGGTATTGACTTGTACTGATGATCAATCACGCAATCGCCGCTTTGGATTGCTCTTGGGCCGTGAAGTGCCTAT
TCCTGAAGCCGAACACCAAATTGGCCAAGTAGTTGAAGGGAAACACAATGCCGCGCAAATTTGCGCTATAGCCAATAAAA
ATAAAGTGGAAATGCCAATTTGTGAGCAAATTAATGCGCTATTGCATGGTATTGTTCATGCCCAAGAGGCCGTGAACAAC
TTGATGAGTCGTCCCGCCAAGGAAGAATAA

Upstream 100 bases:

>100_bases
TTAGTACTCGCACCGATTAATTTTGATGCTTTGTATATGCAGCAGCTGGAAGAAAAACAAAAAGCAACTGGAGCTAAAGA
CGAGACTGTTTCTCACTAAG

Downstream 100 bases:

>100_bases
CCTTTGCCCTTGCAAAGAATCATATTAAATTAGGTTTAGTGCACCAGGACACCAGGACGCAGGTGATACTGGTGGATTGT
CGACATTAACCCATAGCATC

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase [H]

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MNKKTIAMLGAGSWGTAVAIHLAKIGHKTLLWSHNPQHVALMAEQHSNPAYLPGIPFPENLIPSDDLIECVQSADYVIIA
VPSHAFAEITNKIPKPTQGLAWLTKGVDPASHQLLSQLVASRFGVDFPIAVISGPSFAKEVARFLPTALTLASNNTNYQK
KMHQLFHHDNIRVYLSDDLIGVQLCGAVKNILAIACGISDGLGYGANAKAALITRGLAEMTRLGLSMGARQDTFLGLAGV
GDLVLTCTDDQSRNRRFGLLLGREVPIPEAEHQIGQVVEGKHNAAQICAIANKNKVEMPICEQINALLHGIVHAQEAVNN
LMSRPAKEE

Sequences:

>Translated_329_residues
MNKKTIAMLGAGSWGTAVAIHLAKIGHKTLLWSHNPQHVALMAEQHSNPAYLPGIPFPENLIPSDDLIECVQSADYVIIA
VPSHAFAEITNKIPKPTQGLAWLTKGVDPASHQLLSQLVASRFGVDFPIAVISGPSFAKEVARFLPTALTLASNNTNYQK
KMHQLFHHDNIRVYLSDDLIGVQLCGAVKNILAIACGISDGLGYGANAKAALITRGLAEMTRLGLSMGARQDTFLGLAGV
GDLVLTCTDDQSRNRRFGLLLGREVPIPEAEHQIGQVVEGKHNAAQICAIANKNKVEMPICEQINALLHGIVHAQEAVNN
LMSRPAKEE
>Mature_329_residues
MNKKTIAMLGAGSWGTAVAIHLAKIGHKTLLWSHNPQHVALMAEQHSNPAYLPGIPFPENLIPSDDLIECVQSADYVIIA
VPSHAFAEITNKIPKPTQGLAWLTKGVDPASHQLLSQLVASRFGVDFPIAVISGPSFAKEVARFLPTALTLASNNTNYQK
KMHQLFHHDNIRVYLSDDLIGVQLCGAVKNILAIACGISDGLGYGANAKAALITRGLAEMTRLGLSMGARQDTFLGLAGV
GDLVLTCTDDQSRNRRFGLLLGREVPIPEAEHQIGQVVEGKHNAAQICAIANKNKVEMPICEQINALLHGIVHAQEAVNN
LMSRPAKEE

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI24307999, Length=349, Percent_Identity=31.8051575931232, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI33695088, Length=313, Percent_Identity=29.7124600638978, Blast_Score=139, Evalue=4e-33,
Organism=Escherichia coli, GI1790037, Length=335, Percent_Identity=47.4626865671642, Blast_Score=326, Evalue=1e-90,
Organism=Caenorhabditis elegans, GI17507425, Length=355, Percent_Identity=27.6056338028169, Blast_Score=131, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI32564399, Length=354, Percent_Identity=28.2485875706215, Blast_Score=130, Evalue=6e-31,
Organism=Caenorhabditis elegans, GI193210136, Length=363, Percent_Identity=27.5482093663912, Blast_Score=125, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI32564403, Length=363, Percent_Identity=27.5482093663912, Blast_Score=125, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI193210134, Length=346, Percent_Identity=24.8554913294798, Blast_Score=95, Evalue=6e-20,
Organism=Saccharomyces cerevisiae, GI6320181, Length=310, Percent_Identity=28.7096774193548, Blast_Score=117, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6324513, Length=358, Percent_Identity=26.536312849162, Blast_Score=112, Evalue=8e-26,
Organism=Drosophila melanogaster, GI22026922, Length=294, Percent_Identity=27.891156462585, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI17136202, Length=311, Percent_Identity=31.1897106109325, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI17136200, Length=311, Percent_Identity=31.1897106109325, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI17136204, Length=311, Percent_Identity=31.1897106109325, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI45551945, Length=269, Percent_Identity=26.3940520446097, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI281362270, Length=269, Percent_Identity=26.3940520446097, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24648969, Length=216, Percent_Identity=27.7777777777778, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040 [H]

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N [H]

EC number: =1.1.1.94 [H]

Molecular weight: Translated: 35398; Mature: 35398

Theoretical pI: Translated: 7.41; Mature: 7.41

Prosite motif: PS00957 NAD_G3PDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKKTIAMLGAGSWGTAVAIHLAKIGHKTLLWSHNPQHVALMAEQHSNPAYLPGIPFPEN
CCCCEEEEEECCCCHHHHHHHHHHHCCEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCC
LIPSDDLIECVQSADYVIIAVPSHAFAEITNKIPKPTQGLAWLTKGVDPASHQLLSQLVA
CCCCHHHHHHHHCCCEEEEEECCHHHHHHHHCCCCCCCCHHHHHCCCCHHHHHHHHHHHH
SRFGVDFPIAVISGPSFAKEVARFLPTALTLASNNTNYQKKMHQLFHHDNIRVYLSDDLI
HHCCCCCCEEEECCCHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHCCCEEEEEECCCH
GVQLCGAVKNILAIACGISDGLGYGANAKAALITRGLAEMTRLGLSMGARQDTFLGLAGV
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECC
GDLVLTCTDDQSRNRRFGLLLGREVPIPEAEHQIGQVVEGKHNAAQICAIANKNKVEMPI
CCEEEEECCCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHH
CEQINALLHGIVHAQEAVNNLMSRPAKEE
HHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNKKTIAMLGAGSWGTAVAIHLAKIGHKTLLWSHNPQHVALMAEQHSNPAYLPGIPFPEN
CCCCEEEEEECCCCHHHHHHHHHHHCCEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCC
LIPSDDLIECVQSADYVIIAVPSHAFAEITNKIPKPTQGLAWLTKGVDPASHQLLSQLVA
CCCCHHHHHHHHCCCEEEEEECCHHHHHHHHCCCCCCCCHHHHHCCCCHHHHHHHHHHHH
SRFGVDFPIAVISGPSFAKEVARFLPTALTLASNNTNYQKKMHQLFHHDNIRVYLSDDLI
HHCCCCCCEEEECCCHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHCCCEEEEEECCCH
GVQLCGAVKNILAIACGISDGLGYGANAKAALITRGLAEMTRLGLSMGARQDTFLGLAGV
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECC
GDLVLTCTDDQSRNRRFGLLLGREVPIPEAEHQIGQVVEGKHNAAQICAIANKNKVEMPI
CCEEEEECCCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHH
CEQINALLHGIVHAQEAVNNLMSRPAKEE
HHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA