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The map label for this gene is lolC [H]

Identifier: 148359829

GI number: 148359829

Start: 2702904

End: 2704259

Strand: Reverse

Name: lolC [H]

Synonym: LPC_1754

Alternate gene names: 148359829

Gene position: 2704259-2702904 (Counterclockwise)

Preceding gene: 148359831

Following gene: 148359828

Centisome position: 75.61

GC content: 37.54

Gene sequence:

>1356_bases
TTGTCTGATGATGAATTATTAATAAGTTCTTTAAAATCTTTAGGCTTCAATCTTGGCCTTTTCTATAAGTGCTGTACAAT
ACTAACTTTAATCCAGCTGAATACGATTATGTATAAACCATTGGCTCTTTTTATCGGATTACGTTATACGCGTTCACGTA
AGAAAAATCACTTTGTTTCCTTTATTTCCCTAAGTTCCATGTTGGGTATAGGCATGGGAGTGATGGTTTTAATCACTGTT
TTATCAGTGATGAATGGTTTTGATCAGGAAATTCATCGTCGTTTTTTTGGGATGGCGCCTGAAATCACCATAACAGGTCC
TGATGAGCGATTAAGTGATTGGCCTGAAGTGGTTAAAAAGGTTGAAACAATTCCTGGAATAAAGGCAATTGCACCTTATG
TTGGAAGTCAAGGATTATTAACTCATGAAGGCCAGGTTTTGCCTATCGTCCTGACCGGTATTCTGCCAGAAAAAGAACAA
TCAGTAACTCATCTCAATAAGAAACTACTGGCAGGTAATATGGATAATCTGAAACATTTTGGGATTATTCTTGGAAAAGG
TCTTGCGGACAGCCTTGGGGTGATGATTGGGGATAAGGTTACGATAATGATCCCGCAAGCAACAGTAACTCCTGCCGGTA
TGATCCCTCGATTCAAGCGCTTTACCGTTGTAGGTGTTTTTTCTGCGGGTACAGGATTTAATTTTGACACTAAATTGGCA
TTTATTAATATCGAAGATGCTCAAAAATTAATGCAAATGGATAAGAATGACGTTTCAGGTATAAAAATGAAAATTAATAA
TGTATACAAAGCACCTGAATTGTCTTATGAATTATCTGATCTTTTGGGAGAAGGATATCAAGTAGGCAATTGGACCCAGC
AATTTGGAGCTTTTTTTGAAGCAGTTAAAATGGAAAAAACGATGATGTTTATGATTTTATTGCTTATTATTGCTGTGGCA
GCTTTTAATTTGGTGTCCTCTCTGGTAATGGTAGTCAATGACAAACAAGCAGAAATCGCTATTTTAAGAACTATTGGCGC
TACTCCTTCTACCATTTTATGGATTTTTATTGTACAGGGAATGATGGTTGGCCTGGTTGGTACAATTCTTGGGTTGTTAG
GAGGTTTAGTGTTGGCCAATAATGCAACGGAGATAGTTAATGCATTGCAGTCCTTTTTCCAGGTGAAGGTGTTGTCTTCA
AGTATCTATTTTGTTGATTACTTGCCTTCTAAAATTATGTTTCGTGATCTGTGGCAAGTTTGTGCCATGGCATTATTAAT
GAGTTTTGCTGCAACCATTTATCCTGCCTGGCGAGCATCAAAGACAGTCATCGCGGAGGCTTTGCATTATGAATGA

Upstream 100 bases:

>100_bases
GGATGTTCATTTTATGTAAGTTGGCATTTGCTTAATTGATGCCCTAATCGATGAATGGGACTTATTAGATATCCACAGAT
TCTGTGGATAACTATGTGGG

Downstream 100 bases:

>100_bases
CATCATTTTAACAAGTCAAAAACTGTATAAGTCCTACCATGATGGCACATCTACAGTCGAGGTGTTAAAAGGAGTTGACT
TGGCCATAACAAAAGGTGAC

Product: lipoprotein ABC transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 451; Mature: 450

Protein sequence:

>451_residues
MSDDELLISSLKSLGFNLGLFYKCCTILTLIQLNTIMYKPLALFIGLRYTRSRKKNHFVSFISLSSMLGIGMGVMVLITV
LSVMNGFDQEIHRRFFGMAPEITITGPDERLSDWPEVVKKVETIPGIKAIAPYVGSQGLLTHEGQVLPIVLTGILPEKEQ
SVTHLNKKLLAGNMDNLKHFGIILGKGLADSLGVMIGDKVTIMIPQATVTPAGMIPRFKRFTVVGVFSAGTGFNFDTKLA
FINIEDAQKLMQMDKNDVSGIKMKINNVYKAPELSYELSDLLGEGYQVGNWTQQFGAFFEAVKMEKTMMFMILLLIIAVA
AFNLVSSLVMVVNDKQAEIAILRTIGATPSTILWIFIVQGMMVGLVGTILGLLGGLVLANNATEIVNALQSFFQVKVLSS
SIYFVDYLPSKIMFRDLWQVCAMALLMSFAATIYPAWRASKTVIAEALHYE

Sequences:

>Translated_451_residues
MSDDELLISSLKSLGFNLGLFYKCCTILTLIQLNTIMYKPLALFIGLRYTRSRKKNHFVSFISLSSMLGIGMGVMVLITV
LSVMNGFDQEIHRRFFGMAPEITITGPDERLSDWPEVVKKVETIPGIKAIAPYVGSQGLLTHEGQVLPIVLTGILPEKEQ
SVTHLNKKLLAGNMDNLKHFGIILGKGLADSLGVMIGDKVTIMIPQATVTPAGMIPRFKRFTVVGVFSAGTGFNFDTKLA
FINIEDAQKLMQMDKNDVSGIKMKINNVYKAPELSYELSDLLGEGYQVGNWTQQFGAFFEAVKMEKTMMFMILLLIIAVA
AFNLVSSLVMVVNDKQAEIAILRTIGATPSTILWIFIVQGMMVGLVGTILGLLGGLVLANNATEIVNALQSFFQVKVLSS
SIYFVDYLPSKIMFRDLWQVCAMALLMSFAATIYPAWRASKTVIAEALHYE
>Mature_450_residues
SDDELLISSLKSLGFNLGLFYKCCTILTLIQLNTIMYKPLALFIGLRYTRSRKKNHFVSFISLSSMLGIGMGVMVLITVL
SVMNGFDQEIHRRFFGMAPEITITGPDERLSDWPEVVKKVETIPGIKAIAPYVGSQGLLTHEGQVLPIVLTGILPEKEQS
VTHLNKKLLAGNMDNLKHFGIILGKGLADSLGVMIGDKVTIMIPQATVTPAGMIPRFKRFTVVGVFSAGTGFNFDTKLAF
INIEDAQKLMQMDKNDVSGIKMKINNVYKAPELSYELSDLLGEGYQVGNWTQQFGAFFEAVKMEKTMMFMILLLIIAVAA
FNLVSSLVMVVNDKQAEIAILRTIGATPSTILWIFIVQGMMVGLVGTILGLLGGLVLANNATEIVNALQSFFQVKVLSSS
IYFVDYLPSKIMFRDLWQVCAMALLMSFAATIYPAWRASKTVIAEALHYE

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=414, Percent_Identity=36.4734299516908, Blast_Score=248, Evalue=5e-67,
Organism=Escherichia coli, GI1787360, Length=421, Percent_Identity=36.5795724465558, Blast_Score=229, Evalue=3e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 49742; Mature: 49611

Theoretical pI: Translated: 8.70; Mature: 8.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDDELLISSLKSLGFNLGLFYKCCTILTLIQLNTIMYKPLALFIGLRYTRSRKKNHFVS
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
FISLSSMLGIGMGVMVLITVLSVMNGFDQEIHRRFFGMAPEITITGPDERLSDWPEVVKK
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHH
VETIPGIKAIAPYVGSQGLLTHEGQVLPIVLTGILPEKEQSVTHLNKKLLAGNMDNLKHF
HHHCCCHHHHHHHCCCCCCEECCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCHHHH
GIILGKGLADSLGVMIGDKVTIMIPQATVTPAGMIPRFKRFTVVGVFSAGTGFNFDTKLA
HHHHCCCHHHHHCCEECCEEEEEECCCCCCCCCCCCCHHHEEEEEEEECCCCCCCCCEEE
FINIEDAQKLMQMDKNDVSGIKMKINNVYKAPELSYELSDLLGEGYQVGNWTQQFGAFFE
EEEHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHH
AVKMEKTMMFMILLLIIAVAAFNLVSSLVMVVNDKQAEIAILRTIGATPSTILWIFIVQG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEEECCCCCHHHHHHHHHHHH
MMVGLVGTILGLLGGLVLANNATEIVNALQSFFQVKVLSSSIYFVDYLPSKIMFRDLWQV
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHH
CAMALLMSFAATIYPAWRASKTVIAEALHYE
HHHHHHHHHHHHHHHHHCCHHHHHHHHHCCC
>Mature Secondary Structure 
SDDELLISSLKSLGFNLGLFYKCCTILTLIQLNTIMYKPLALFIGLRYTRSRKKNHFVS
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
FISLSSMLGIGMGVMVLITVLSVMNGFDQEIHRRFFGMAPEITITGPDERLSDWPEVVKK
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHH
VETIPGIKAIAPYVGSQGLLTHEGQVLPIVLTGILPEKEQSVTHLNKKLLAGNMDNLKHF
HHHCCCHHHHHHHCCCCCCEECCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCHHHH
GIILGKGLADSLGVMIGDKVTIMIPQATVTPAGMIPRFKRFTVVGVFSAGTGFNFDTKLA
HHHHCCCHHHHHCCEECCEEEEEECCCCCCCCCCCCCHHHEEEEEEEECCCCCCCCCEEE
FINIEDAQKLMQMDKNDVSGIKMKINNVYKAPELSYELSDLLGEGYQVGNWTQQFGAFFE
EEEHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHH
AVKMEKTMMFMILLLIIAVAAFNLVSSLVMVVNDKQAEIAILRTIGATPSTILWIFIVQG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEEECCCCCHHHHHHHHHHHH
MMVGLVGTILGLLGGLVLANNATEIVNALQSFFQVKVLSSSIYFVDYLPSKIMFRDLWQV
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHH
CAMALLMSFAATIYPAWRASKTVIAEALHYE
HHHHHHHHHHHHHHHHHCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]