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The map label for this gene is rtcB [C]

Identifier: 148359741

GI number: 148359741

Start: 2600624

End: 2602054

Strand: Reverse

Name: rtcB [C]

Synonym: LPC_1665

Alternate gene names: 148359741

Gene position: 2602054-2600624 (Counterclockwise)

Preceding gene: 148359742

Following gene: 148359740

Centisome position: 72.75

GC content: 42.7

Gene sequence:

>1431_bases
ATGGATTTAAGTCTCTTGAAAAAAATAAATGATTTTGAATGGCAAATACCGCAACATGGAAAGATGTTGGTGCCAGGAGT
TATTTTCGCTTCAGAACAGCTGATTCTTGATATGGATATGAAAGTTTACGAACAATTATCTAATGTTGCTACTTTGCCGG
GAATTGTTTCTGCTGCATATGCCATGCCTGATGCGCATTGGGGATATGGTTTTCCGATTGGCGGTGTCGCTGCTTTTGAT
CCGGATGATGGAGGGGTTATTTCAGCAGGTGGTGTGGGCTTTGACATTTCATGCGGAGTGAGGCTCTTATCTACTGGATT
GAAGCGAGATGAATTGGAGTCTGTTAAAGTTAGCCTTGCAGACGCTTTATTTACTCATATTCCAGCTGGAGTAGGTAGTA
GAAGCGGCATTCATTTAACTATCAAACAGCTCGATGATATGATGCGAGGAGGCGCACAGTGGGCAGTAAAACAAGGCTAT
GGCGAAGTCGCTGATTTAGAGCGTATAGAGGATCGCGGTTGTGTGGAAGGAGCTATCCCTGATTTTGTCTCTGAGCAAGC
TAAAAAGCGCCAGAAAAATGAAATGGGTACCTTGGGTTCAGGTAATCATTATCTTGAGGTGCAGGAAGTCAGGCAAATCT
ACTGTTCCGATACAGCAACGGCTTTAAATTTGCATGAAGGGGATATTGTAGTGAGTATCCATTGTGGTTCCAGAGGATTA
GGGCATCAAATTGGTACAGATTACCTCCGTTCCATGGTTATTGAATCACAACATTATGGTATCAAGCTGGCGGATAGGGA
GTTGGCTTGTGCTCCTATTCATTCAAAGCTAGGGGAAAATTACCTGGGCGCTATGAGAGCAGGAATAAATTGCGCTTTAG
CCAACAGAGAAATCATCACTCATTTTATGCGCAATGTGTTTCAGGATATTTTACCCCGCACTCAGATTGATCTAATCTAT
GATGTTTCTCACAATACTTGTAAAGAAGAATTTCATGAGATAGATGGCAAGAAAAAGCGCTTATTTGTTCATCGAAAAGG
AGCAACTCGTGCCTTGGGTCCAGGTCACCCACAACTACCTAAAGCTGTTTCTCATATAGGTCAACCTGTGATTATTGGAG
GGAGTATGGGAACAGGCTCCTATGTATTAGCAGGAGTCAAAGGTTCTGAGCATAAATCTTTTAGCTCGGCATGTCATGGA
GCAGGTCGCGCTATGAGTCGTCATCAGGCGATGAAGAAATGGAACGGGAAAGACATAGTAGATAAATTGGCTCAACAAGG
GATTTTAATTCGTAGTGGATCATACCGTGGGGTTGCTGAGGAAGCTCCAGGAGCTTATAAAGATGTTCATTCTATTGTTG
ATGCCGCTGAAATGTCGGGTTTGGCAAAAAAAGTTGCTAAATTAATTCCCATCATTTGTGTCAAAGGTTAA

Upstream 100 bases:

>100_bases
CTATACTGAATTAAAAGTATACAAAAATAATGACATTTGGATAGCTCAATGTGTCGTTGATGTATAAACTCCTTAGCAGG
AATTAATGTGGTGAACAGTG

Downstream 100 bases:

>100_bases
CAATCCATTGTTTATTGAGGTGAATGGAGCAGCTTATAATTGTAAGGAATCTGTAAATAAAATAAACTAAGAGCAATTTT
CGATAAATTTTTAGACTAAA

Product: replication factor C subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 476; Mature: 476

Protein sequence:

>476_residues
MDLSLLKKINDFEWQIPQHGKMLVPGVIFASEQLILDMDMKVYEQLSNVATLPGIVSAAYAMPDAHWGYGFPIGGVAAFD
PDDGGVISAGGVGFDISCGVRLLSTGLKRDELESVKVSLADALFTHIPAGVGSRSGIHLTIKQLDDMMRGGAQWAVKQGY
GEVADLERIEDRGCVEGAIPDFVSEQAKKRQKNEMGTLGSGNHYLEVQEVRQIYCSDTATALNLHEGDIVVSIHCGSRGL
GHQIGTDYLRSMVIESQHYGIKLADRELACAPIHSKLGENYLGAMRAGINCALANREIITHFMRNVFQDILPRTQIDLIY
DVSHNTCKEEFHEIDGKKKRLFVHRKGATRALGPGHPQLPKAVSHIGQPVIIGGSMGTGSYVLAGVKGSEHKSFSSACHG
AGRAMSRHQAMKKWNGKDIVDKLAQQGILIRSGSYRGVAEEAPGAYKDVHSIVDAAEMSGLAKKVAKLIPIICVKG

Sequences:

>Translated_476_residues
MDLSLLKKINDFEWQIPQHGKMLVPGVIFASEQLILDMDMKVYEQLSNVATLPGIVSAAYAMPDAHWGYGFPIGGVAAFD
PDDGGVISAGGVGFDISCGVRLLSTGLKRDELESVKVSLADALFTHIPAGVGSRSGIHLTIKQLDDMMRGGAQWAVKQGY
GEVADLERIEDRGCVEGAIPDFVSEQAKKRQKNEMGTLGSGNHYLEVQEVRQIYCSDTATALNLHEGDIVVSIHCGSRGL
GHQIGTDYLRSMVIESQHYGIKLADRELACAPIHSKLGENYLGAMRAGINCALANREIITHFMRNVFQDILPRTQIDLIY
DVSHNTCKEEFHEIDGKKKRLFVHRKGATRALGPGHPQLPKAVSHIGQPVIIGGSMGTGSYVLAGVKGSEHKSFSSACHG
AGRAMSRHQAMKKWNGKDIVDKLAQQGILIRSGSYRGVAEEAPGAYKDVHSIVDAAEMSGLAKKVAKLIPIICVKG
>Mature_476_residues
MDLSLLKKINDFEWQIPQHGKMLVPGVIFASEQLILDMDMKVYEQLSNVATLPGIVSAAYAMPDAHWGYGFPIGGVAAFD
PDDGGVISAGGVGFDISCGVRLLSTGLKRDELESVKVSLADALFTHIPAGVGSRSGIHLTIKQLDDMMRGGAQWAVKQGY
GEVADLERIEDRGCVEGAIPDFVSEQAKKRQKNEMGTLGSGNHYLEVQEVRQIYCSDTATALNLHEGDIVVSIHCGSRGL
GHQIGTDYLRSMVIESQHYGIKLADRELACAPIHSKLGENYLGAMRAGINCALANREIITHFMRNVFQDILPRTQIDLIY
DVSHNTCKEEFHEIDGKKKRLFVHRKGATRALGPGHPQLPKAVSHIGQPVIIGGSMGTGSYVLAGVKGSEHKSFSSACHG
AGRAMSRHQAMKKWNGKDIVDKLAQQGILIRSGSYRGVAEEAPGAYKDVHSIVDAAEMSGLAKKVAKLIPIICVKG

Specific function: Unknown

COG id: COG1690

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0027 (rtcB) family [H]

Homologues:

Organism=Homo sapiens, GI7657015, Length=498, Percent_Identity=43.7751004016064, Blast_Score=388, Evalue=1e-108,
Organism=Escherichia coli, GI2367224, Length=441, Percent_Identity=29.7052154195011, Blast_Score=134, Evalue=9e-33,
Organism=Caenorhabditis elegans, GI17506665, Length=438, Percent_Identity=46.3470319634703, Blast_Score=376, Evalue=1e-104,
Organism=Drosophila melanogaster, GI24585217, Length=499, Percent_Identity=44.2885771543086, Blast_Score=385, Evalue=1e-107,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001233 [H]

Pfam domain/function: PF01139 UPF0027 [H]

EC number: NA

Molecular weight: Translated: 51475; Mature: 51475

Theoretical pI: Translated: 7.48; Mature: 7.48

Prosite motif: PS01288 UPF0027

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLSLLKKINDFEWQIPQHGKMLVPGVIFASEQLILDMDMKVYEQLSNVATLPGIVSAAY
CCHHHHHHCCCCCEECCCCCCEEECEEEEECCCEEEECCHHHHHHHHHHHHHHHHHHHHH
AMPDAHWGYGFPIGGVAAFDPDDGGVISAGGVGFDISCGVRLLSTGLKRDELESVKVSLA
HCCCCCCCCCCCCCCEEEECCCCCCEEECCCCCEEHHCCHHHHHCCCCHHHHHHHHHHHH
DALFTHIPAGVGSRSGIHLTIKQLDDMMRGGAQWAVKQGYGEVADLERIEDRGCVEGAIP
HHHHHHCCCCCCCCCCEEEEHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHCCCCCCCCH
DFVSEQAKKRQKNEMGTLGSGNHYLEVQEVRQIYCSDTATALNLHEGDIVVSIHCGSRGL
HHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHCCCCEEEEEECCCEEEEEECCCCCC
GHQIGTDYLRSMVIESQHYGIKLADRELACAPIHSKLGENYLGAMRAGINCALANREIIT
CHHHHHHHHHHHHHCCCCCCEEEECCCCEEEHHHHHHCHHHHHHHHHCCEEEECCHHHHH
HFMRNVFQDILPRTQIDLIYDVSHNTCKEEFHEIDGKKKRLFVHRKGATRALGPGHPQLP
HHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCHH
KAVSHIGQPVIIGGSMGTGSYVLAGVKGSEHKSFSSACHGAGRAMSRHQAMKKWNGKDIV
HHHHHCCCCEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHH
DKLAQQGILIRSGSYRGVAEEAPGAYKDVHSIVDAAEMSGLAKKVAKLIPIICVKG
HHHHHCCEEEECCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECC
>Mature Secondary Structure
MDLSLLKKINDFEWQIPQHGKMLVPGVIFASEQLILDMDMKVYEQLSNVATLPGIVSAAY
CCHHHHHHCCCCCEECCCCCCEEECEEEEECCCEEEECCHHHHHHHHHHHHHHHHHHHHH
AMPDAHWGYGFPIGGVAAFDPDDGGVISAGGVGFDISCGVRLLSTGLKRDELESVKVSLA
HCCCCCCCCCCCCCCEEEECCCCCCEEECCCCCEEHHCCHHHHHCCCCHHHHHHHHHHHH
DALFTHIPAGVGSRSGIHLTIKQLDDMMRGGAQWAVKQGYGEVADLERIEDRGCVEGAIP
HHHHHHCCCCCCCCCCEEEEHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHCCCCCCCCH
DFVSEQAKKRQKNEMGTLGSGNHYLEVQEVRQIYCSDTATALNLHEGDIVVSIHCGSRGL
HHHHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHCCCCEEEEEECCCEEEEEECCCCCC
GHQIGTDYLRSMVIESQHYGIKLADRELACAPIHSKLGENYLGAMRAGINCALANREIIT
CHHHHHHHHHHHHHCCCCCCEEEECCCCEEEHHHHHHCHHHHHHHHHCCEEEECCHHHHH
HFMRNVFQDILPRTQIDLIYDVSHNTCKEEFHEIDGKKKRLFVHRKGATRALGPGHPQLP
HHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCHH
KAVSHIGQPVIIGGSMGTGSYVLAGVKGSEHKSFSSACHGAGRAMSRHQAMKKWNGKDIV
HHHHHCCCCEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHH
DKLAQQGILIRSGSYRGVAEEAPGAYKDVHSIVDAAEMSGLAKKVAKLIPIICVKG
HHHHHCCEEEECCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA