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The map label for this gene is ahcY [H]

Identifier: 148359711

GI number: 148359711

Start: 2547354

End: 2548427

Strand: Reverse

Name: ahcY [H]

Synonym: LPC_1632

Alternate gene names: 148359711

Gene position: 2548427-2547354 (Counterclockwise)

Preceding gene: 148359713

Following gene: 148359707

Centisome position: 71.26

GC content: 39.94

Gene sequence:

>1074_bases
ATGTATCACCCGCAAATTGCGCCATTTATGCATCTTCAGATTAATGAATGGGGCAAAAACAGGCCACTGGAAGGGGTGAA
AATACTGCATCATGTGCCTTTGGTTCCCAATACGCTGCTAAAAATAGCAGCTCTTGTCGCTGCAAATGCTGAGGTGACCG
TAACCAATCCGGCTTCTTTTTGTCAGGCACATCCTGATGCGATTACTTGTCTTCATAAATCAGGAATTCCTTATGTTGAA
AATCTTGATCTTTTAAGAGATGAAACGTTCGATGTTTATCTGGATTGTGGTGGGCAACTTTATCAGAGTCTCGGAAGACC
TTTGAGGGGAGCTATTGAGCTAACGGGTTCAGGGGATCAGTATTATCGTAGTCTCAAAACACTTGATTTTCCGGTTATAA
GCATTGATCACACAATGACGAAACAATTGGAAACAGTATTTGGCTGTGCTGAAAGTTCTCACCAAGCGATTCAAAAACTC
ACTGGTGTCGATCCCACAAACAAGAATTGGCTAATCTTTGGGTTTGGTAAAATAGGGCGAGGGCTCGCTTATTTTTGTGT
GGAACATCAAGTACCAGTTACTGTAGTGGACAGTTCAGTCCATCAATGTGATTTAGCTTCCAATCTTGGTATAGAGTCTA
TTAGACCTGAGGAGCATGATAAGCTCGAAAAAGCAGTGGCTAAAGCAGATATTATTTTAACTGCAACGGGCGGTAAAAAT
ATCATGAGCAAATACCCCAGAGCCTGGTTTGATGGCAAAATCTTGGGGAATTTAGGGCTGCATGATGAGTTTGGTCCCAA
TTTCACCTCTCAGGATGTATTATACGATAAAAAACCTATTAATTTTTGCCTATATGATCCTACGCCAATGATTTTTATAG
ATCCTGAGTTTTATTTGCATAATCTGGGATGTTTATTGCTTTTACAGGGAAATTTTCCTCGGGGAATGCATGATATTCCT
GAAGATATAGATTCCTCTATTATTAAAGACTGGTGCCAATATCATAGGCGTTCTGAAAAAAGTATTCGACGTTGGTTTCT
GACTTCCCAGGATTTTTCTCTTAAAACAAATTAA

Upstream 100 bases:

>100_bases
AATTCGTGTTATTGCTAATGAGTTTTATTATAGTATTGTCATTCTTTCTCATACTCATATGGTCTAAACAATGCACCAGG
AGTTATTAAAGTATTTAGAA

Downstream 100 bases:

>100_bases
TATAAACAGTTCGAATAAGACGGTTTATAGCCGCTTTAATTAGTTTCCTTAATTGAAAATTACTTTTTCAGGTCTTCTTA
ATATTAATAAAATGTGGGGA

Product: adenosylhomocysteinase

Products: NA

Alternate protein names: S-adenosyl-L-homocysteine hydrolase; AdoHcyase [H]

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MYHPQIAPFMHLQINEWGKNRPLEGVKILHHVPLVPNTLLKIAALVAANAEVTVTNPASFCQAHPDAITCLHKSGIPYVE
NLDLLRDETFDVYLDCGGQLYQSLGRPLRGAIELTGSGDQYYRSLKTLDFPVISIDHTMTKQLETVFGCAESSHQAIQKL
TGVDPTNKNWLIFGFGKIGRGLAYFCVEHQVPVTVVDSSVHQCDLASNLGIESIRPEEHDKLEKAVAKADIILTATGGKN
IMSKYPRAWFDGKILGNLGLHDEFGPNFTSQDVLYDKKPINFCLYDPTPMIFIDPEFYLHNLGCLLLLQGNFPRGMHDIP
EDIDSSIIKDWCQYHRRSEKSIRRWFLTSQDFSLKTN

Sequences:

>Translated_357_residues
MYHPQIAPFMHLQINEWGKNRPLEGVKILHHVPLVPNTLLKIAALVAANAEVTVTNPASFCQAHPDAITCLHKSGIPYVE
NLDLLRDETFDVYLDCGGQLYQSLGRPLRGAIELTGSGDQYYRSLKTLDFPVISIDHTMTKQLETVFGCAESSHQAIQKL
TGVDPTNKNWLIFGFGKIGRGLAYFCVEHQVPVTVVDSSVHQCDLASNLGIESIRPEEHDKLEKAVAKADIILTATGGKN
IMSKYPRAWFDGKILGNLGLHDEFGPNFTSQDVLYDKKPINFCLYDPTPMIFIDPEFYLHNLGCLLLLQGNFPRGMHDIP
EDIDSSIIKDWCQYHRRSEKSIRRWFLTSQDFSLKTN
>Mature_357_residues
MYHPQIAPFMHLQINEWGKNRPLEGVKILHHVPLVPNTLLKIAALVAANAEVTVTNPASFCQAHPDAITCLHKSGIPYVE
NLDLLRDETFDVYLDCGGQLYQSLGRPLRGAIELTGSGDQYYRSLKTLDFPVISIDHTMTKQLETVFGCAESSHQAIQKL
TGVDPTNKNWLIFGFGKIGRGLAYFCVEHQVPVTVVDSSVHQCDLASNLGIESIRPEEHDKLEKAVAKADIILTATGGKN
IMSKYPRAWFDGKILGNLGLHDEFGPNFTSQDVLYDKKPINFCLYDPTPMIFIDPEFYLHNLGCLLLLQGNFPRGMHDIP
EDIDSSIIKDWCQYHRRSEKSIRRWFLTSQDFSLKTN

Specific function: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine [H]

COG id: COG0499

COG function: function code H; S-adenosylhomocysteine hydrolase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenosylhomocysteinase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000043
- InterPro:   IPR015878
- InterPro:   IPR020082 [H]

Pfam domain/function: PF05221 AdoHcyase; PF00670 AdoHcyase_NAD [H]

EC number: =3.3.1.1 [H]

Molecular weight: Translated: 40198; Mature: 40198

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYHPQIAPFMHLQINEWGKNRPLEGVKILHHVPLVPNTLLKIAALVAANAEVTVTNPASF
CCCCCCCCEEEEEEECCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEECCHHH
CQAHPDAITCLHKSGIPYVENLDLLRDETFDVYLDCGGQLYQSLGRPLRGAIELTGSGDQ
HHCCCCHHEEECCCCCCHHHCCHHHHCCCEEEEECCCHHHHHHHCCCCEEEEEEECCCHH
YYRSLKTLDFPVISIDHTMTKQLETVFGCAESSHQAIQKLTGVDPTNKNWLIFGFGKIGR
HHHHHHHCCCCEEEECHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCEEEEECCCCCC
GLAYFCVEHQVPVTVVDSSVHQCDLASNLGIESIRPEEHDKLEKAVAKADIILTATGGKN
CEEEEEECCCCCEEEECCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCEEEEECCCCH
IMSKYPRAWFDGKILGNLGLHDEFGPNFTSQDVLYDKKPINFCLYDPTPMIFIDPEFYLH
HHHHCCCCCCCCEEEECCCCCCCCCCCCCCCCCEECCCCCCEEEECCCCEEEECCHHHHH
NLGCLLLLQGNFPRGMHDIPEDIDSSIIKDWCQYHRRSEKSIRRWFLTSQDFSLKTN
CCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECC
>Mature Secondary Structure
MYHPQIAPFMHLQINEWGKNRPLEGVKILHHVPLVPNTLLKIAALVAANAEVTVTNPASF
CCCCCCCCEEEEEEECCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCEEEEECCHHH
CQAHPDAITCLHKSGIPYVENLDLLRDETFDVYLDCGGQLYQSLGRPLRGAIELTGSGDQ
HHCCCCHHEEECCCCCCHHHCCHHHHCCCEEEEECCCHHHHHHHCCCCEEEEEEECCCHH
YYRSLKTLDFPVISIDHTMTKQLETVFGCAESSHQAIQKLTGVDPTNKNWLIFGFGKIGR
HHHHHHHCCCCEEEECHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCEEEEECCCCCC
GLAYFCVEHQVPVTVVDSSVHQCDLASNLGIESIRPEEHDKLEKAVAKADIILTATGGKN
CEEEEEECCCCCEEEECCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCEEEEECCCCH
IMSKYPRAWFDGKILGNLGLHDEFGPNFTSQDVLYDKKPINFCLYDPTPMIFIDPEFYLH
HHHHCCCCCCCCEEEECCCCCCCCCCCCCCCCCEECCCCCCEEEECCCCEEEECCHHHHH
NLGCLLLLQGNFPRGMHDIPEDIDSSIIKDWCQYHRRSEKSIRRWFLTSQDFSLKTN
CCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]