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The map label for this gene is pdxH [H]

Identifier: 148359669

GI number: 148359669

Start: 2470410

End: 2470997

Strand: Reverse

Name: pdxH [H]

Synonym: LPC_1588

Alternate gene names: 148359669

Gene position: 2470997-2470410 (Counterclockwise)

Preceding gene: 148359670

Following gene: 148359667

Centisome position: 69.09

GC content: 38.95

Gene sequence:

>588_bases
ATGGCCAGAAACGACCCCATTGCCCTTCTAACAACATGGATTTCAGAGGAATTGGAAAGAGGAGCACCTAATCCACAACA
TGCCACATTATCTACGGCAGGCAAAGATTCTATTCCCCATGGGCGTGTTATCGCCATTCGCGAAATCAATGAGCAAGGCT
TATTATTTTTTACCCAGCGAGGAACCAGAAAGGTGGTCGAAATGACCTATAATCCTATCGTATCTCTGACTTTTTGGTTT
GAGTTATTTGAAAGAGAAGTCATGATAGACGGTTCAGCAAGGCCATTATCGGAAAGCGAAAATCAAGCATACTGGGATAC
CTATCCACCTTTCGCGCAAATCAGATTTCATAGTTATGCGCCTACTTCATCACAAGTTATATCCAGTAAACAACTGATTG
AAAATAAAAGAAAAATATTGATTTCCCGGTTTCACGATAAGTCATTGCCTATGAGTGAATATTATTGTGGTTTCAGAATC
ATTCCCACACGCATGGTTTTTTATACTTATAGAACGGATGAATTGTCCGATGTCGTAGAATATTGTTTTATAAAAAACAA
TTGGGAGAAGAATTTGCTTTCTCCTTAA

Upstream 100 bases:

>100_bases
GCAAGTGAATTATGGCTCACAATATTCACCAACGTAATGAGACATCGCTAGTCCGTATCATTATTAACGCCAGAAAATAT
TTACAATAGGTATTCAAGTT

Downstream 100 bases:

>100_bases
ATATCAATTTGTTTAAGCCTCATGATTGATGCAACAATATTTTTTTATTACATCCAATACCCATTGCAGCGGTTTATGAT
TTGATAATCGTTTATGATAG

Product: pyridoxamine 5'-phosphate oxidase

Products: NA

Alternate protein names: PNP/PMP oxidase; PNPOx; Pyridoxal 5'-phosphate synthase [H]

Number of amino acids: Translated: 195; Mature: 194

Protein sequence:

>195_residues
MARNDPIALLTTWISEELERGAPNPQHATLSTAGKDSIPHGRVIAIREINEQGLLFFTQRGTRKVVEMTYNPIVSLTFWF
ELFEREVMIDGSARPLSESENQAYWDTYPPFAQIRFHSYAPTSSQVISSKQLIENKRKILISRFHDKSLPMSEYYCGFRI
IPTRMVFYTYRTDELSDVVEYCFIKNNWEKNLLSP

Sequences:

>Translated_195_residues
MARNDPIALLTTWISEELERGAPNPQHATLSTAGKDSIPHGRVIAIREINEQGLLFFTQRGTRKVVEMTYNPIVSLTFWF
ELFEREVMIDGSARPLSESENQAYWDTYPPFAQIRFHSYAPTSSQVISSKQLIENKRKILISRFHDKSLPMSEYYCGFRI
IPTRMVFYTYRTDELSDVVEYCFIKNNWEKNLLSP
>Mature_194_residues
ARNDPIALLTTWISEELERGAPNPQHATLSTAGKDSIPHGRVIAIREINEQGLLFFTQRGTRKVVEMTYNPIVSLTFWFE
LFEREVMIDGSARPLSESENQAYWDTYPPFAQIRFHSYAPTSSQVISSKQLIENKRKILISRFHDKSLPMSEYYCGFRII
PTRMVFYTYRTDELSDVVEYCFIKNNWEKNLLSP

Specific function: Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) [H]

COG id: COG0259

COG function: function code H; Pyridoxamine-phosphate oxidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxamine 5'-phosphate oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922498, Length=178, Percent_Identity=26.9662921348315, Blast_Score=85, Evalue=4e-17,
Organism=Escherichia coli, GI1787926, Length=191, Percent_Identity=28.2722513089005, Blast_Score=98, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17553712, Length=171, Percent_Identity=25.1461988304094, Blast_Score=70, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6319509, Length=201, Percent_Identity=26.865671641791, Blast_Score=75, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24644901, Length=181, Percent_Identity=25.9668508287293, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI45551845, Length=181, Percent_Identity=25.9668508287293, Blast_Score=72, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000659
- InterPro:   IPR019740
- InterPro:   IPR019576
- InterPro:   IPR011576
- InterPro:   IPR012349
- InterPro:   IPR009002 [H]

Pfam domain/function: PF10590 PNPOx_C; PF01243 Pyridox_oxidase [H]

EC number: =1.4.3.5 [H]

Molecular weight: Translated: 22739; Mature: 22608

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARNDPIALLTTWISEELERGAPNPQHATLSTAGKDSIPHGRVIAIREINEQGLLFFTQR
CCCCCCHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCEEEEEEECCCCEEEEECC
GTRKVVEMTYNPIVSLTFWFELFEREVMIDGSARPLSESENQAYWDTYPPFAQIRFHSYA
CCCEEEHHHCCCHHHHHHHHHHHHCEEEECCCCCCCCCCCCCEECCCCCCCEEEEEECCC
PTSSQVISSKQLIENKRKILISRFHDKSLPMSEYYCGFRIIPTRMVFYTYRTDELSDVVE
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCEEEECEEEEEEEECCHHHHHHHH
YCFIKNNWEKNLLSP
HHHHCCCCCCCCCCC
>Mature Secondary Structure 
ARNDPIALLTTWISEELERGAPNPQHATLSTAGKDSIPHGRVIAIREINEQGLLFFTQR
CCCCCHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCEEEEEEECCCCEEEEECC
GTRKVVEMTYNPIVSLTFWFELFEREVMIDGSARPLSESENQAYWDTYPPFAQIRFHSYA
CCCEEEHHHCCCHHHHHHHHHHHHCEEEECCCCCCCCCCCCCEECCCCCCCEEEEEECCC
PTSSQVISSKQLIENKRKILISRFHDKSLPMSEYYCGFRIIPTRMVFYTYRTDELSDVVE
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCEEEECEEEEEEEECCHHHHHHHH
YCFIKNNWEKNLLSP
HHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA