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The map label for this gene is 148359591

Identifier: 148359591

GI number: 148359591

Start: 2372670

End: 2374358

Strand: Reverse

Name: 148359591

Synonym: LPC_1503

Alternate gene names: NA

Gene position: 2374358-2372670 (Counterclockwise)

Preceding gene: 148359592

Following gene: 148359585

Centisome position: 66.39

GC content: 40.5

Gene sequence:

>1689_bases
ATGGGTTTGAAATCAGGAATATTGGGATTAAGTCTTTTATCGCTTGCTTGTGGCAGTTTTGCTATGACTGAAACTGAAAC
AATCAGAGTTATCATTAAATATAAACAGCAACCAGCCACCATGGCTTCACTAAAATCACAAGTCATTAAATCTGTTCAAA
TACCCGTTAAAGAAATGAAGCCTATGGCAAATGGCGCTTATTCGCTTATTTTTGATACATCGAATTCCCATGCTATTGTC
AAGGCTAAAGAAGAAGATGTTACAGCCAAAGTTTTAGAACGTTTGCGCAAAAATCCCAATGTACTTTATGCAGTTAAAGA
CAGAATAGGACATTTTAAGCCTCTCCCTGATCCAGTAATAAACCAGGAGTTAAGTCAATTGTTATCCCATGAGAGTCAAT
GGGATGAATTCGAAAGGCCAGCGGGAATTCGTCTGGAATCCAAGCCTGGTTTAAGAGATGGCGCATGGGCATATACTACA
GGAAAGTCCAGGAAGCCGATAGTTGTTGCGGTTTTAGATACTGGGATTGCATTGAATGACAGTTTAGTGAATAACCTTGT
AAAGGATAATGAAGGTAATGTATTTGGATGGAATTTTGCCGGGAATAATAATGATTTATCTGATGAAACCAGATCCTACC
ATGGCACCCATGTTGCCGGTACCATTGCCGGTTATGGCGATGTCATGAACGGAGTTGGTGAGGATTTAAAAATTCTGACT
GTTAAAATTCCTGCCGAGAATGGTATGTTTTATGAAAGTGCTGTAGTGAATAGTATCTATTGGGCTGTTGGAGGTGATGT
TCCGGGAGTTCCTAAAAATATACATCCAGCCAAGGTATTAAATATGAGTTTTGGTGTCGATTTAGAGCCTGGGAAAGAAA
TTGATTATTGCGACGAAGCTTTACAAGAGGCTTTATTCTTTGCTCGCAAAAAAGGGGCTGTAGTCGCGGTTGCTGCCGGA
AATGATAATGTTTGGGAACACTATAATGCTCCTGCAGTGTGCAATGGAACGATCAAGGTTGCTTCCACCGGACCAGAAGG
CTTGCGTTCGTACTTTTCAAATTATGGGCCCAGTATAACCCTCGCAGCACCGGGAGGTGATAAGCGTTATGGCACTTCGG
GAGGTATTTTATCTACCGTAAACCCGGGAGGTGGATACAATTCATCAGGCTTTGATTTTTATCAAGGGACGAGTATGGCT
TCGCCTCATGTAGCCGGGGTAGCAGGTTTAATTTTTGCTGTCAGTAATAAGGCTTTGAAACCTGAACAAGTTGAACAAAT
TTTATATGTTACTACGCATGAGTTTGGGCAAAGCAACGACACCAATAAATCTTGTGTCGGCAAAAAACCTTGTGGACATG
GAATATTGGATGCGGATAATGCTGTGCAGGCAGCATTAAATGGTTATGATGTCTTATTCTCTGCGCCTAAAATGATTGCT
CTGGCAACGCATGAATGTGGCGAGAATAGATTAAAACCTGGTAAAAATATCATTAATGACAGTACTGCGACTTGGATTCA
AATTAAATCAAGCTGTGAAACTGGTGTAAGCTATCAGAAGCCACGTATTGAAAAAGCCAAGGATGGGAAAATTTATGCTT
ATTATGGTTCCGTAAGCTATGAATTGGATCAATCAGCTTATAAAGAATGTCGTGTCGTTGGATATGATGGTGTAGGCTGT
TATTTATAA

Upstream 100 bases:

>100_bases
TTGATTCTTGAGTTGATATTTATTCTCCTGCATACTGAGGTGGTTTTATTTTTAAAAATTGGTCAAGGCTACGGATTGAC
TTTAAAAAGGAGATTGAAGT

Downstream 100 bases:

>100_bases
TATCAAATGAAATTCGATTCTCAGTTTTAAGACGTTTTTGATGAGGGAAGCATTCAGAGCCAATTTACTGGTTACTTATG
GAATCCTTCTCTCATCAAAT

Product: serine metalloprotease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 562; Mature: 561

Protein sequence:

>562_residues
MGLKSGILGLSLLSLACGSFAMTETETIRVIIKYKQQPATMASLKSQVIKSVQIPVKEMKPMANGAYSLIFDTSNSHAIV
KAKEEDVTAKVLERLRKNPNVLYAVKDRIGHFKPLPDPVINQELSQLLSHESQWDEFERPAGIRLESKPGLRDGAWAYTT
GKSRKPIVVAVLDTGIALNDSLVNNLVKDNEGNVFGWNFAGNNNDLSDETRSYHGTHVAGTIAGYGDVMNGVGEDLKILT
VKIPAENGMFYESAVVNSIYWAVGGDVPGVPKNIHPAKVLNMSFGVDLEPGKEIDYCDEALQEALFFARKKGAVVAVAAG
NDNVWEHYNAPAVCNGTIKVASTGPEGLRSYFSNYGPSITLAAPGGDKRYGTSGGILSTVNPGGGYNSSGFDFYQGTSMA
SPHVAGVAGLIFAVSNKALKPEQVEQILYVTTHEFGQSNDTNKSCVGKKPCGHGILDADNAVQAALNGYDVLFSAPKMIA
LATHECGENRLKPGKNIINDSTATWIQIKSSCETGVSYQKPRIEKAKDGKIYAYYGSVSYELDQSAYKECRVVGYDGVGC
YL

Sequences:

>Translated_562_residues
MGLKSGILGLSLLSLACGSFAMTETETIRVIIKYKQQPATMASLKSQVIKSVQIPVKEMKPMANGAYSLIFDTSNSHAIV
KAKEEDVTAKVLERLRKNPNVLYAVKDRIGHFKPLPDPVINQELSQLLSHESQWDEFERPAGIRLESKPGLRDGAWAYTT
GKSRKPIVVAVLDTGIALNDSLVNNLVKDNEGNVFGWNFAGNNNDLSDETRSYHGTHVAGTIAGYGDVMNGVGEDLKILT
VKIPAENGMFYESAVVNSIYWAVGGDVPGVPKNIHPAKVLNMSFGVDLEPGKEIDYCDEALQEALFFARKKGAVVAVAAG
NDNVWEHYNAPAVCNGTIKVASTGPEGLRSYFSNYGPSITLAAPGGDKRYGTSGGILSTVNPGGGYNSSGFDFYQGTSMA
SPHVAGVAGLIFAVSNKALKPEQVEQILYVTTHEFGQSNDTNKSCVGKKPCGHGILDADNAVQAALNGYDVLFSAPKMIA
LATHECGENRLKPGKNIINDSTATWIQIKSSCETGVSYQKPRIEKAKDGKIYAYYGSVSYELDQSAYKECRVVGYDGVGC
YL
>Mature_561_residues
GLKSGILGLSLLSLACGSFAMTETETIRVIIKYKQQPATMASLKSQVIKSVQIPVKEMKPMANGAYSLIFDTSNSHAIVK
AKEEDVTAKVLERLRKNPNVLYAVKDRIGHFKPLPDPVINQELSQLLSHESQWDEFERPAGIRLESKPGLRDGAWAYTTG
KSRKPIVVAVLDTGIALNDSLVNNLVKDNEGNVFGWNFAGNNNDLSDETRSYHGTHVAGTIAGYGDVMNGVGEDLKILTV
KIPAENGMFYESAVVNSIYWAVGGDVPGVPKNIHPAKVLNMSFGVDLEPGKEIDYCDEALQEALFFARKKGAVVAVAAGN
DNVWEHYNAPAVCNGTIKVASTGPEGLRSYFSNYGPSITLAAPGGDKRYGTSGGILSTVNPGGGYNSSGFDFYQGTSMAS
PHVAGVAGLIFAVSNKALKPEQVEQILYVTTHEFGQSNDTNKSCVGKKPCGHGILDADNAVQAALNGYDVLFSAPKMIAL
ATHECGENRLKPGKNIINDSTATWIQIKSSCETGVSYQKPRIEKAKDGKIYAYYGSVSYELDQSAYKECRVVGYDGVGCY
L

Specific function: Unknown

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320775, Length=359, Percent_Identity=27.2980501392758, Blast_Score=73, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6324576, Length=335, Percent_Identity=27.7611940298507, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500
- InterPro:   IPR002884 [H]

Pfam domain/function: PF01483 P_proprotein; PF00082 Peptidase_S8 [H]

EC number: NA

Molecular weight: Translated: 60480; Mature: 60349

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00583 PFKB_KINASES_1 ; PS00136 SUBTILASE_ASP ; PS00137 SUBTILASE_HIS ; PS00138 SUBTILASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLKSGILGLSLLSLACGSFAMTETETIRVIIKYKQQPATMASLKSQVIKSVQIPVKEMK
CCCCHHHHHHHHHHHHHCCEEECCCCEEEEEEEECCCCHHHHHHHHHHHHHHCCCHHHCC
PMANGAYSLIFDTSNSHAIVKAKEEDVTAKVLERLRKNPNVLYAVKDRIGHFKPLPDPVI
CCCCCCEEEEEECCCCEEEEEECCCCHHHHHHHHHHCCCCEEEEEEHHCCCCCCCCCHHH
NQELSQLLSHESQWDEFERPAGIRLESKPGLRDGAWAYTTGKSRKPIVVAVLDTGIALND
HHHHHHHHHCCHHHHHHCCCCCCEECCCCCCCCCCEEEECCCCCCCEEEEEECCCCEECH
SLVNNLVKDNEGNVFGWNFAGNNNDLSDETRSYHGTHVAGTIAGYGDVMNGVGEDLKILT
HHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHCCCCEEEEEHHHHHHHHHCCCCCEEEEE
VKIPAENGMFYESAVVNSIYWAVGGDVPGVPKNIHPAKVLNMSFGVDLEPGKEIDYCDEA
EEEECCCCCEEHHHHHHHHHEEECCCCCCCCCCCCCHHEEEEECCCCCCCCCCCHHHHHH
LQEALFFARKKGAVVAVAAGNDNVWEHYNAPAVCNGTIKVASTGPEGLRSYFSNYGPSIT
HHHHHHHHHCCCCEEEEECCCCCCHHHCCCCEEECCEEEEECCCHHHHHHHHHHCCCEEE
LAAPGGDKRYGTSGGILSTVNPGGGYNSSGFDFYQGTSMASPHVAGVAGLIFAVSNKALK
EECCCCCCCCCCCCCEEEECCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHCCCCCC
PEQVEQILYVTTHEFGQSNDTNKSCVGKKPCGHGILDADNAVQAALNGYDVLFSAPKMIA
HHHHHHEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCEEEECCCCEEE
LATHECGENRLKPGKNIINDSTATWIQIKSSCETGVSYQKPRIEKAKDGKIYAYYGSVSY
EEECCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCEEEEEECCEEE
ELDQSAYKECRVVGYDGVGCYL
EECHHHHHCCEEEEECCCCCCC
>Mature Secondary Structure 
GLKSGILGLSLLSLACGSFAMTETETIRVIIKYKQQPATMASLKSQVIKSVQIPVKEMK
CCCHHHHHHHHHHHHHCCEEECCCCEEEEEEEECCCCHHHHHHHHHHHHHHCCCHHHCC
PMANGAYSLIFDTSNSHAIVKAKEEDVTAKVLERLRKNPNVLYAVKDRIGHFKPLPDPVI
CCCCCCEEEEEECCCCEEEEEECCCCHHHHHHHHHHCCCCEEEEEEHHCCCCCCCCCHHH
NQELSQLLSHESQWDEFERPAGIRLESKPGLRDGAWAYTTGKSRKPIVVAVLDTGIALND
HHHHHHHHHCCHHHHHHCCCCCCEECCCCCCCCCCEEEECCCCCCCEEEEEECCCCEECH
SLVNNLVKDNEGNVFGWNFAGNNNDLSDETRSYHGTHVAGTIAGYGDVMNGVGEDLKILT
HHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHCCCCEEEEEHHHHHHHHHCCCCCEEEEE
VKIPAENGMFYESAVVNSIYWAVGGDVPGVPKNIHPAKVLNMSFGVDLEPGKEIDYCDEA
EEEECCCCCEEHHHHHHHHHEEECCCCCCCCCCCCCHHEEEEECCCCCCCCCCCHHHHHH
LQEALFFARKKGAVVAVAAGNDNVWEHYNAPAVCNGTIKVASTGPEGLRSYFSNYGPSIT
HHHHHHHHHCCCCEEEEECCCCCCHHHCCCCEEECCEEEEECCCHHHHHHHHHHCCCEEE
LAAPGGDKRYGTSGGILSTVNPGGGYNSSGFDFYQGTSMASPHVAGVAGLIFAVSNKALK
EECCCCCCCCCCCCCEEEECCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHCCCCCC
PEQVEQILYVTTHEFGQSNDTNKSCVGKKPCGHGILDADNAVQAALNGYDVLFSAPKMIA
HHHHHHEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCEEEECCCCEEE
LATHECGENRLKPGKNIINDSTATWIQIKSSCETGVSYQKPRIEKAKDGKIYAYYGSVSY
EEECCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCEEEEEECCEEE
ELDQSAYKECRVVGYDGVGCYL
EECHHHHHCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA