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The map label for this gene is uup [H]

Identifier: 148359151

GI number: 148359151

Start: 1851110

End: 1852570

Strand: Reverse

Name: uup [H]

Synonym: LPC_1043

Alternate gene names: 148359151

Gene position: 1852570-1851110 (Counterclockwise)

Preceding gene: 148359153

Following gene: 148359150

Centisome position: 51.8

GC content: 39.29

Gene sequence:

>1461_bases
ATGAACCATAAACCGATTCAATTTAAAGACCTCAGTCTTATCTATCCGCATAAAACCTGTTTTCAAGACTTTAGTGGTGA
AATCCATTTTGCTGATCGCATTGCACTGATTGGCCGTAATGGCTCAGGAAAATCAACGCTACTCAAGATGCTTTGTGGTC
TTTTTTTAGCCCCTGCTGGCGAAATTAAAATACCCCATGATGTTCGCTTTGGTCATTTACCTCAAGTGCTTGAGGATTGT
CCTGATTTAAGTGGCGGTCAGCGATTAAACCGAGTATTAAGCAAAATACTGTCGGATGAGCCTAATGTTTTGTTGTTAGA
TGAGCCCACAAATCATCTGGACAGCCGTAATCGTCGTTCTTTAATGCGCATGCTTGAGCATTATCATGGGACATTGATCA
TAGCCTCTCATGATACAGAACTCATCAATACAGTCACAGATACTCTATGGCATATTGATTTAGGTCAAGTGACCGTATTC
AGAGGAATTTATTTTAATTATCAACAAATTCTTGAAGACAAGAAAGCATCGATTGAACAGGAGTTATCAAGGATTGCACG
ACAGAAAAAAGAATCACATCTTGCTTTGATGAAAGAGCAGGAGCGTAATAAACGTGCGCGTGTCCAGGGTGAAAAGAAGA
TAGCCCAACGCAAATGGCCAACGGTTCGATCTCATACAAAGCTCGGTTCAGCAATTACAACAGGCAATAAACGATTAAGT
CACATTAACTATAAAAAACAACAATTACTCGAGGAGCTTTCCTCTCTAAACTTTCCGGAGGTAATTAAGCCCAAATTTAG
GTTAAAGGGACTTGGGCACCATAAACCCTTAATCAGGATTCAAGACGCTTCTGTTGCCTATGAGGCTGTTGTGATTCTTG
AAGATATTCATTTTCACCTTAGCGGTTGCGAACGAGTGGCATTACATGGCAACAATGCTTCAGGTAAGTCGACCTTTGTC
AAAGCGATCTTGGGGGAAAGTCAAATTAAGAGAACAGGGGAATGGGCTGTGCCTGATTGCAATACAATAGGCTATATCGA
TCAACATTATCAACATTTGAACTTCAATGAAACAGTCCTGGATTTAATGCGCTCCAGTATGTCCCATGCATCTCATACAG
AAATTCGTGCTCATTTAAATGATTTTTTATTTCGCAAAAATGAAGAAGTAGAAATTAAGGTCAAAAATCTTTCTGGTGGT
GAAAAGGCAAGGTTATCGATGGCATTGATTGCTGCAAATCCACCTAAACTACTTATTTTAGATGAGATCACTAACAATGT
AGATTTGGAAACACGCACTCATATCATTCAGGTGCTGCGTGAATTTCAAGGTGCAATGCTGGTTATTTCTCATGACTATG
ACTTTTTAGAATCCATTCACATTGAAACCAGGTATCAGATTCATCAAGGGAAGATACATCATTTCAATGAGAAACAATTA
GAGGTAGTGCATCATGACTAA

Upstream 100 bases:

>100_bases
AAATTACATCTTAAGTACGCCCAACTATAGGGCAAAGTGAACAAAGTCCTTTGTGACTTTTAGTTTTTACTGTCCTGGCA
GACATGCTTAAGAGTAAATC

Downstream 100 bases:

>100_bases
TCGTTTACCTAATCACTTAGGCTCTTTTATGTGGCATTTTTTAAAACCATATCGAGGCATAGTGATATTATTTATCCTGT
TTGCCCTATTGGCCGGGTTT

Product: ABC transporter ATP-binding protein Uup

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 486; Mature: 486

Protein sequence:

>486_residues
MNHKPIQFKDLSLIYPHKTCFQDFSGEIHFADRIALIGRNGSGKSTLLKMLCGLFLAPAGEIKIPHDVRFGHLPQVLEDC
PDLSGGQRLNRVLSKILSDEPNVLLLDEPTNHLDSRNRRSLMRMLEHYHGTLIIASHDTELINTVTDTLWHIDLGQVTVF
RGIYFNYQQILEDKKASIEQELSRIARQKKESHLALMKEQERNKRARVQGEKKIAQRKWPTVRSHTKLGSAITTGNKRLS
HINYKKQQLLEELSSLNFPEVIKPKFRLKGLGHHKPLIRIQDASVAYEAVVILEDIHFHLSGCERVALHGNNASGKSTFV
KAILGESQIKRTGEWAVPDCNTIGYIDQHYQHLNFNETVLDLMRSSMSHASHTEIRAHLNDFLFRKNEEVEIKVKNLSGG
EKARLSMALIAANPPKLLILDEITNNVDLETRTHIIQVLREFQGAMLVISHDYDFLESIHIETRYQIHQGKIHHFNEKQL
EVVHHD

Sequences:

>Translated_486_residues
MNHKPIQFKDLSLIYPHKTCFQDFSGEIHFADRIALIGRNGSGKSTLLKMLCGLFLAPAGEIKIPHDVRFGHLPQVLEDC
PDLSGGQRLNRVLSKILSDEPNVLLLDEPTNHLDSRNRRSLMRMLEHYHGTLIIASHDTELINTVTDTLWHIDLGQVTVF
RGIYFNYQQILEDKKASIEQELSRIARQKKESHLALMKEQERNKRARVQGEKKIAQRKWPTVRSHTKLGSAITTGNKRLS
HINYKKQQLLEELSSLNFPEVIKPKFRLKGLGHHKPLIRIQDASVAYEAVVILEDIHFHLSGCERVALHGNNASGKSTFV
KAILGESQIKRTGEWAVPDCNTIGYIDQHYQHLNFNETVLDLMRSSMSHASHTEIRAHLNDFLFRKNEEVEIKVKNLSGG
EKARLSMALIAANPPKLLILDEITNNVDLETRTHIIQVLREFQGAMLVISHDYDFLESIHIETRYQIHQGKIHHFNEKQL
EVVHHD
>Mature_486_residues
MNHKPIQFKDLSLIYPHKTCFQDFSGEIHFADRIALIGRNGSGKSTLLKMLCGLFLAPAGEIKIPHDVRFGHLPQVLEDC
PDLSGGQRLNRVLSKILSDEPNVLLLDEPTNHLDSRNRRSLMRMLEHYHGTLIIASHDTELINTVTDTLWHIDLGQVTVF
RGIYFNYQQILEDKKASIEQELSRIARQKKESHLALMKEQERNKRARVQGEKKIAQRKWPTVRSHTKLGSAITTGNKRLS
HINYKKQQLLEELSSLNFPEVIKPKFRLKGLGHHKPLIRIQDASVAYEAVVILEDIHFHLSGCERVALHGNNASGKSTFV
KAILGESQIKRTGEWAVPDCNTIGYIDQHYQHLNFNETVLDLMRSSMSHASHTEIRAHLNDFLFRKNEEVEIKVKNLSGG
EKARLSMALIAANPPKLLILDEITNNVDLETRTHIIQVLREFQGAMLVISHDYDFLESIHIETRYQIHQGKIHHFNEKQL
EVVHHD

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=380, Percent_Identity=25.5263157894737, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI10947137, Length=399, Percent_Identity=26.8170426065163, Blast_Score=113, Evalue=5e-25,
Organism=Homo sapiens, GI27881506, Length=399, Percent_Identity=26.8170426065163, Blast_Score=113, Evalue=5e-25,
Organism=Homo sapiens, GI69354671, Length=373, Percent_Identity=26.5415549597855, Blast_Score=106, Evalue=6e-23,
Organism=Homo sapiens, GI10947135, Length=373, Percent_Identity=26.5415549597855, Blast_Score=105, Evalue=6e-23,
Organism=Escherichia coli, GI1789751, Length=399, Percent_Identity=30.0751879699248, Blast_Score=158, Evalue=1e-39,
Organism=Escherichia coli, GI2367384, Length=408, Percent_Identity=27.4509803921569, Blast_Score=146, Evalue=3e-36,
Organism=Escherichia coli, GI1787182, Length=397, Percent_Identity=29.2191435768262, Blast_Score=129, Evalue=6e-31,
Organism=Escherichia coli, GI1787041, Length=414, Percent_Identity=26.8115942028986, Blast_Score=122, Evalue=8e-29,
Organism=Escherichia coli, GI1788165, Length=191, Percent_Identity=30.3664921465969, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17559834, Length=378, Percent_Identity=27.5132275132275, Blast_Score=141, Evalue=9e-34,
Organism=Caenorhabditis elegans, GI17555318, Length=420, Percent_Identity=28.0952380952381, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17553372, Length=381, Percent_Identity=25.4593175853018, Blast_Score=104, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6321121, Length=396, Percent_Identity=26.5151515151515, Blast_Score=125, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6320874, Length=403, Percent_Identity=26.302729528536, Blast_Score=118, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6324314, Length=185, Percent_Identity=28.6486486486486, Blast_Score=71, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6323278, Length=176, Percent_Identity=28.4090909090909, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24641342, Length=385, Percent_Identity=27.7922077922078, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24666836, Length=375, Percent_Identity=27.7333333333333, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24642252, Length=426, Percent_Identity=25.8215962441315, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI18859989, Length=426, Percent_Identity=25.8215962441315, Blast_Score=114, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 55714; Mature: 55714

Theoretical pI: Translated: 8.68; Mature: 8.68

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHKPIQFKDLSLIYPHKTCFQDFSGEIHFADRIALIGRNGSGKSTLLKMLCGLFLAPAG
CCCCCCEEECCEEECCCHHHHHHCCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHCCCC
EIKIPHDVRFGHLPQVLEDCPDLSGGQRLNRVLSKILSDEPNVLLLDEPTNHLDSRNRRS
CEECCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHH
LMRMLEHYHGTLIIASHDTELINTVTDTLWHIDLGQVTVFRGIYFNYQQILEDKKASIEQ
HHHHHHHHCCEEEEEECCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ELSRIARQKKESHLALMKEQERNKRARVQGEKKIAQRKWPTVRSHTKLGSAITTGNKRLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCHHHHHHCCCCEECCCCHHH
HINYKKQQLLEELSSLNFPEVIKPKFRLKGLGHHKPLIRIQDASVAYEAVVILEDIHFHL
HCCHHHHHHHHHHHHCCCCHHCCCCHHCCCCCCCCCEEEEECCCHHHHHEEEEHHHHHHH
SGCERVALHGNNASGKSTFVKAILGESQIKRTGEWAVPDCNTIGYIDQHYQHLNFNETVL
CCCEEEEEECCCCCCHHHHHHHHHCHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCCHHHH
DLMRSSMSHASHTEIRAHLNDFLFRKNEEVEIKVKNLSGGEKARLSMALIAANPPKLLIL
HHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCEEEEEEEECCCCCEEEE
DEITNNVDLETRTHIIQVLREFQGAMLVISHDYDFLESIHIETRYQIHQGKIHHFNEKQL
ECCCCCCCCHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHEEEEEECCCCCCCCCCEE
EVVHHD
EEEECC
>Mature Secondary Structure
MNHKPIQFKDLSLIYPHKTCFQDFSGEIHFADRIALIGRNGSGKSTLLKMLCGLFLAPAG
CCCCCCEEECCEEECCCHHHHHHCCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHCCCC
EIKIPHDVRFGHLPQVLEDCPDLSGGQRLNRVLSKILSDEPNVLLLDEPTNHLDSRNRRS
CEECCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHH
LMRMLEHYHGTLIIASHDTELINTVTDTLWHIDLGQVTVFRGIYFNYQQILEDKKASIEQ
HHHHHHHHCCEEEEEECCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ELSRIARQKKESHLALMKEQERNKRARVQGEKKIAQRKWPTVRSHTKLGSAITTGNKRLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCHHHHHHCCCCEECCCCHHH
HINYKKQQLLEELSSLNFPEVIKPKFRLKGLGHHKPLIRIQDASVAYEAVVILEDIHFHL
HCCHHHHHHHHHHHHCCCCHHCCCCHHCCCCCCCCCEEEEECCCHHHHHEEEEHHHHHHH
SGCERVALHGNNASGKSTFVKAILGESQIKRTGEWAVPDCNTIGYIDQHYQHLNFNETVL
CCCEEEEEECCCCCCHHHHHHHHHCHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCCHHHH
DLMRSSMSHASHTEIRAHLNDFLFRKNEEVEIKVKNLSGGEKARLSMALIAANPPKLLIL
HHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCEEEEEEEECCCCCEEEE
DEITNNVDLETRTHIIQVLREFQGAMLVISHDYDFLESIHIETRYQIHQGKIHHFNEKQL
ECCCCCCCCHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHEEEEEECCCCCCCCCCEE
EVVHHD
EEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]