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The map label for this gene is moeZ [H]

Identifier: 148359105

GI number: 148359105

Start: 1803113

End: 1804240

Strand: Direct

Name: moeZ [H]

Synonym: LPC_0993

Alternate gene names: 148359105

Gene position: 1803113-1804240 (Clockwise)

Preceding gene: 148359104

Following gene: 148359116

Centisome position: 50.42

GC content: 36.97

Gene sequence:

>1128_bases
ATGAACAAATCAAATTTGGCAATGAATGAATTAACCCGCTATTCTCAACAAATAAAGATGGAAGAAATTGGATTAGACGG
ACAGGAGAAACTTAAGAATTCTCGAGTATTATGCATTGGGCTTGGCGGTTTGGGTTCGCCTCTCTTATTTTACCTTGCTG
CAGCAGGTGTTGGAGTATTAGGGATTGTCGATGATGACATCATTGAACTAAGTAATTTGCATAGGCAGATTCTTTATAAT
CATACCCATATTAATAAAAAAAAGGCTGTTACTGCAAAAAAGCAACTTCTGGCTATTAATCCCCTGATTCAAGTTGAATC
TTACTCCAGTAGATTAACAGAGGAAAATGCGGCTGAGCTAATTACGCAGTATGACATCATCGCAGATGGAACCGATAATT
TTTATACGCGATATTTGATTCACAGCATTTGCTTTGAGCTGGAAAAACCTTATGTGTATGCTAGTGCCTCAGGTTTCCAA
GGGTATTGCTCTATATTCCACGGTAAACAAGATCCCTGCCTCCATTGTATCTTCCCGGTTTCTGTAAGCGATATCAATAT
GCCCAATTGCGAGGGGGCCGGGGTAATTGGTACTTTACCCGGGATGCTAGGTATTATTCAGGCAACAGAAATAATCAAAT
GGATACTACAAATTGGCAATCCATTAAAAAAGCGTTTGCTTGCTATTAACTTGTTAACAATGACCTTTAAGAACATCATT
ATTTCAAGAAATCCGGATTGTGAATTCTGCATTCAGAATCAGTCAATTAGACAATTAATTAATCCTGTTAATTGTTCAAC
TCAAATTGAGCCATGCCATCATAGAATAACTCTTGATGAGTTTTATCAATTATTTACGAATAATAAAAACATTCATCTAA
TTGATGTTCGTAGTACAAAGGAGCATCAAAAACAAAATATAGGAGGTATTGTGCTTCCTGTAGATGAGTTGCCTCAACGC
TTACATGAACTAAACCCTAATCGGCTTATTATTCTGTACTGCCAGTCGGGAAAACGAAGCAAGATGGCATTAGATATACT
TCTCAAGGCTGGCTTTGCTTCTGTTAAATATATAGAAAATGGTTTAAAGGGAGTCACTGTCAATTACAATAAAGACATGC
CCCAATAA

Upstream 100 bases:

>100_bases
ACAAAAATTGATGGTGTGTCAGTGATCTCTGCCATTACAAAAGCATCAGTACCTTTAGTTGCAGCCAAACAATTTTTAAC
TCAAATGAATGAATCACATA

Downstream 100 bases:

>100_bases
TTCTCCCCTCCTAAAAAGGAAGCTGAAATTAAATAAGTTTGTTTTTACCTTCGGCAATATTATTTAGCAGATAAGCGAGT
CGACACCCAGCCAGAAGTAT

Product: sulfurylase ThiF

Products: NA

Alternate protein names: Sulfur carrier protein CysO adenylyltransferase; Sulfur carrier protein CysO sulfurtransferase [H]

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MNKSNLAMNELTRYSQQIKMEEIGLDGQEKLKNSRVLCIGLGGLGSPLLFYLAAAGVGVLGIVDDDIIELSNLHRQILYN
HTHINKKKAVTAKKQLLAINPLIQVESYSSRLTEENAAELITQYDIIADGTDNFYTRYLIHSICFELEKPYVYASASGFQ
GYCSIFHGKQDPCLHCIFPVSVSDINMPNCEGAGVIGTLPGMLGIIQATEIIKWILQIGNPLKKRLLAINLLTMTFKNII
ISRNPDCEFCIQNQSIRQLINPVNCSTQIEPCHHRITLDEFYQLFTNNKNIHLIDVRSTKEHQKQNIGGIVLPVDELPQR
LHELNPNRLIILYCQSGKRSKMALDILLKAGFASVKYIENGLKGVTVNYNKDMPQ

Sequences:

>Translated_375_residues
MNKSNLAMNELTRYSQQIKMEEIGLDGQEKLKNSRVLCIGLGGLGSPLLFYLAAAGVGVLGIVDDDIIELSNLHRQILYN
HTHINKKKAVTAKKQLLAINPLIQVESYSSRLTEENAAELITQYDIIADGTDNFYTRYLIHSICFELEKPYVYASASGFQ
GYCSIFHGKQDPCLHCIFPVSVSDINMPNCEGAGVIGTLPGMLGIIQATEIIKWILQIGNPLKKRLLAINLLTMTFKNII
ISRNPDCEFCIQNQSIRQLINPVNCSTQIEPCHHRITLDEFYQLFTNNKNIHLIDVRSTKEHQKQNIGGIVLPVDELPQR
LHELNPNRLIILYCQSGKRSKMALDILLKAGFASVKYIENGLKGVTVNYNKDMPQ
>Mature_375_residues
MNKSNLAMNELTRYSQQIKMEEIGLDGQEKLKNSRVLCIGLGGLGSPLLFYLAAAGVGVLGIVDDDIIELSNLHRQILYN
HTHINKKKAVTAKKQLLAINPLIQVESYSSRLTEENAAELITQYDIIADGTDNFYTRYLIHSICFELEKPYVYASASGFQ
GYCSIFHGKQDPCLHCIFPVSVSDINMPNCEGAGVIGTLPGMLGIIQATEIIKWILQIGNPLKKRLLAINLLTMTFKNII
ISRNPDCEFCIQNQSIRQLINPVNCSTQIEPCHHRITLDEFYQLFTNNKNIHLIDVRSTKEHQKQNIGGIVLPVDELPQR
LHELNPNRLIILYCQSGKRSKMALDILLKAGFASVKYIENGLKGVTVNYNKDMPQ

Specific function: Catalyzes the conversion of the sulfur carrier protein CysO to CysO-thiocarboxylate. The reaction is thought to proceed in two steps:first, ATP-dependent activation of CysO as acyl- adenylate (CysO-COOAMP), followed by sulfur transfer to give CysO- thioca

COG id: COG0476

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 rhodanese domain [H]

Homologues:

Organism=Homo sapiens, GI7657339, Length=310, Percent_Identity=35.1612903225806, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI4885649, Length=149, Percent_Identity=27.5167785234899, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI38045948, Length=164, Percent_Identity=32.3170731707317, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI150417996, Length=147, Percent_Identity=29.2517006802721, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI23510338, Length=177, Percent_Identity=28.2485875706215, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI23510340, Length=177, Percent_Identity=28.2485875706215, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI38045942, Length=197, Percent_Identity=26.3959390862944, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI38045944, Length=197, Percent_Identity=26.3959390862944, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1787048, Length=250, Percent_Identity=36, Blast_Score=164, Evalue=7e-42,
Organism=Escherichia coli, GI87082356, Length=244, Percent_Identity=38.5245901639344, Blast_Score=156, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI17540406, Length=304, Percent_Identity=34.2105263157895, Blast_Score=179, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI193203301, Length=163, Percent_Identity=29.4478527607362, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71984476, Length=180, Percent_Identity=28.3333333333333, Blast_Score=79, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6321903, Length=404, Percent_Identity=30.1980198019802, Blast_Score=172, Evalue=7e-44,
Organism=Saccharomyces cerevisiae, GI6320598, Length=168, Percent_Identity=34.5238095238095, Blast_Score=83, Evalue=8e-17,
Organism=Saccharomyces cerevisiae, GI6322639, Length=165, Percent_Identity=27.2727272727273, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24582879, Length=392, Percent_Identity=35.2040816326531, Blast_Score=209, Evalue=2e-54,
Organism=Drosophila melanogaster, GI24660640, Length=150, Percent_Identity=29.3333333333333, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI20129973, Length=204, Percent_Identity=28.4313725490196, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28573937, Length=177, Percent_Identity=28.2485875706215, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007901
- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR001763
- InterPro:   IPR000594 [H]

Pfam domain/function: PF05237 MoeZ_MoeB; PF00581 Rhodanese; PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 42128; Mature: 42128

Theoretical pI: Translated: 7.89; Mature: 7.89

Prosite motif: PS50206 RHODANESE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKSNLAMNELTRYSQQIKMEEIGLDGQEKLKNSRVLCIGLGGLGSPLLFYLAAAGVGVL
CCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCEEEEECCCCCHHHHHHHHHHCCCEE
GIVDDDIIELSNLHRQILYNHTHINKKKAVTAKKQLLAINPLIQVESYSSRLTEENAAEL
EECCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHEEECCEEEEECHHHHHCHHHHHHH
ITQYDIIADGTDNFYTRYLIHSICFELEKPYVYASASGFQGYCSIFHGKQDPCLHCIFPV
HHHHHEEECCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHCCCCCCCEEEEEEC
SVSDINMPNCEGAGVIGTLPGMLGIIQATEIIKWILQIGNPLKKRLLAINLLTMTFKNII
EECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
ISRNPDCEFCIQNQSIRQLINPVNCSTQIEPCHHRITLDEFYQLFTNNKNIHLIDVRSTK
CCCCCCCCEEECCHHHHHHCCCCCCCCCCCCHHHCCCHHHHHHHHCCCCCEEEEEECCCH
EHQKQNIGGIVLPVDELPQRLHELNPNRLIILYCQSGKRSKMALDILLKAGFASVKYIEN
HHHHHCCCEEEEEHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHCCHHHHHHHC
GLKGVTVNYNKDMPQ
CCCEEEEECCCCCCC
>Mature Secondary Structure
MNKSNLAMNELTRYSQQIKMEEIGLDGQEKLKNSRVLCIGLGGLGSPLLFYLAAAGVGVL
CCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCEEEEECCCCCHHHHHHHHHHCCCEE
GIVDDDIIELSNLHRQILYNHTHINKKKAVTAKKQLLAINPLIQVESYSSRLTEENAAEL
EECCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHEEECCEEEEECHHHHHCHHHHHHH
ITQYDIIADGTDNFYTRYLIHSICFELEKPYVYASASGFQGYCSIFHGKQDPCLHCIFPV
HHHHHEEECCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHCCCCCCCEEEEEEC
SVSDINMPNCEGAGVIGTLPGMLGIIQATEIIKWILQIGNPLKKRLLAINLLTMTFKNII
EECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
ISRNPDCEFCIQNQSIRQLINPVNCSTQIEPCHHRITLDEFYQLFTNNKNIHLIDVRSTK
CCCCCCCCEEECCHHHHHHCCCCCCCCCCCCHHHCCCHHHHHHHHCCCCCEEEEEECCCH
EHQKQNIGGIVLPVDELPQRLHELNPNRLIILYCQSGKRSKMALDILLKAGFASVKYIEN
HHHHHCCCEEEEEHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHCCHHHHHHHC
GLKGVTVNYNKDMPQ
CCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]