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The map label for this gene is engA

Identifier: 148359075

GI number: 148359075

Start: 1771910

End: 1773298

Strand: Reverse

Name: engA

Synonym: LPC_0962

Alternate gene names: 148359075

Gene position: 1773298-1771910 (Counterclockwise)

Preceding gene: 148359076

Following gene: 148359071

Centisome position: 49.58

GC content: 37.08

Gene sequence:

>1389_bases
ATGATCCCTGTCATCGCTTTAGTTGGGCGTCCCAATGTTGGAAAGTCTACTTTGTTTAATAGAATTACTAAAACGCAGGA
TGCTCTTGTCGCAGATTTTCCTGGCTTGACAAGGGATAGACAATATGGACACGCTCAACATGAAAACAAGTCCTTTATTA
TTGTTGATACCGGGGGCATAGGAGTTGATGACATTGAAGTAGATACTTTGATGTCAAGACAGTCTCAAGTTGCTTTAAAC
GAAGCAAATGTGATTCTTTTCCTGGTCGATGGCCGTTCAGGACTAACAGGTATAGATCAGCAAATTGCACAAGCATTAAG
AAAACTTAATAAAAAGGTACATCTTGTTGTCAATAAAACAGATGGAATGAATGAAGATATTGCTTGTGCCGATTTTCAAT
CATTAGGCATTACTGATGTCCATGCTATATCTGCATCTCATGGTGGAGGCATCAGTTCACTACTCGAAGAAATTCTCGAG
CCATTTACAACAGAAACGCATGAAGCAACTGATGATAAAGCGATCAAAATTGCTTTTGCGGGGCGCCCTAATGTTGGAAA
ATCAACTTTGATAAACAGGATATTAGGGGAAGAAAGAGTAGTTGTTTATGACATGCCCGGAACAACTCGAGATAGTATTT
CAATACCCTTTACAAGAGAAGATAAGCAATATGTGCTTATTGATACTGCTGGTGTACGGCGTAAGTCTCGAATTGATGAA
AAAATAGAAAAGTTTTCTGTCATCAAAACTCTGCAAGCTATAAAAGAAGCTCATGTCTGTTTGTTGCTTCTTGATGCAAA
TGAAGGCATTACCGATCAAGATATGAATTTGCTTGGTTTTATTATTGAATCTGGTAAAGCGCTAGTTATTGCTGTGAATA
AATGGGACGGCCTGGAAGAAGATCATAAAGAAAAAATAAAGTCAGAACTGTCAAGAAGGTTGCATTTTGCAAATTTTGCA
AAAATCAGATTTATTTCAGCATTACATGGGAGCGGGGTAGGTGGATTATTTAAAGATATTAATGAAGCCTATCATTCAGC
AATACAATCCTTTTCTACTCCAAAACTAACCAGATTATTACAAGATATCAGCGCAAAGCATACACCACCATGCATCAATG
GCCGACGAATAAAATTACGTTATGCTCACCTTGGCGGACACAATCCTCCTGTCATTGTTATTCATGGAAATCAACTCGAT
GCCTTGCCAGAAAGTTATAAACGTTATTTAAACAATGAGTTTATTAAGCATTTAGGATTAGTAGGTACTCCTTTAAAAAT
CGAGTTTAAAGGAGGTCAAAATCCATTTGCCAATAAAAAAAATAAATTATCACAAAGGCAAGTGAACAAGAAGAAACGAT
TAATGCGATGGGCAAAAAGCAAGAAATAG

Upstream 100 bases:

>100_bases
CTTTCTGGTGGAGTAACAGTATCACCGAGTGTTTCTGGTAAAAATATGTATGTATTAACCAATAATGGAATGCTCAATCA
ACTTTCAGTGAGCTAATAAA

Downstream 100 bases:

>100_bases
CACTCCGGTTCAGCTCAGCCAGATTTAAATTGTTATAATGAAAAAAAGTATCAATTGGGTACTAATCTCTTCTTATTAAT
CTGCTTTGAGTGTTAATACA

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA

Number of amino acids: Translated: 462; Mature: 462

Protein sequence:

>462_residues
MIPVIALVGRPNVGKSTLFNRITKTQDALVADFPGLTRDRQYGHAQHENKSFIIVDTGGIGVDDIEVDTLMSRQSQVALN
EANVILFLVDGRSGLTGIDQQIAQALRKLNKKVHLVVNKTDGMNEDIACADFQSLGITDVHAISASHGGGISSLLEEILE
PFTTETHEATDDKAIKIAFAGRPNVGKSTLINRILGEERVVVYDMPGTTRDSISIPFTREDKQYVLIDTAGVRRKSRIDE
KIEKFSVIKTLQAIKEAHVCLLLLDANEGITDQDMNLLGFIIESGKALVIAVNKWDGLEEDHKEKIKSELSRRLHFANFA
KIRFISALHGSGVGGLFKDINEAYHSAIQSFSTPKLTRLLQDISAKHTPPCINGRRIKLRYAHLGGHNPPVIVIHGNQLD
ALPESYKRYLNNEFIKHLGLVGTPLKIEFKGGQNPFANKKNKLSQRQVNKKKRLMRWAKSKK

Sequences:

>Translated_462_residues
MIPVIALVGRPNVGKSTLFNRITKTQDALVADFPGLTRDRQYGHAQHENKSFIIVDTGGIGVDDIEVDTLMSRQSQVALN
EANVILFLVDGRSGLTGIDQQIAQALRKLNKKVHLVVNKTDGMNEDIACADFQSLGITDVHAISASHGGGISSLLEEILE
PFTTETHEATDDKAIKIAFAGRPNVGKSTLINRILGEERVVVYDMPGTTRDSISIPFTREDKQYVLIDTAGVRRKSRIDE
KIEKFSVIKTLQAIKEAHVCLLLLDANEGITDQDMNLLGFIIESGKALVIAVNKWDGLEEDHKEKIKSELSRRLHFANFA
KIRFISALHGSGVGGLFKDINEAYHSAIQSFSTPKLTRLLQDISAKHTPPCINGRRIKLRYAHLGGHNPPVIVIHGNQLD
ALPESYKRYLNNEFIKHLGLVGTPLKIEFKGGQNPFANKKNKLSQRQVNKKKRLMRWAKSKK
>Mature_462_residues
MIPVIALVGRPNVGKSTLFNRITKTQDALVADFPGLTRDRQYGHAQHENKSFIIVDTGGIGVDDIEVDTLMSRQSQVALN
EANVILFLVDGRSGLTGIDQQIAQALRKLNKKVHLVVNKTDGMNEDIACADFQSLGITDVHAISASHGGGISSLLEEILE
PFTTETHEATDDKAIKIAFAGRPNVGKSTLINRILGEERVVVYDMPGTTRDSISIPFTREDKQYVLIDTAGVRRKSRIDE
KIEKFSVIKTLQAIKEAHVCLLLLDANEGITDQDMNLLGFIIESGKALVIAVNKWDGLEEDHKEKIKSELSRRLHFANFA
KIRFISALHGSGVGGLFKDINEAYHSAIQSFSTPKLTRLLQDISAKHTPPCINGRRIKLRYAHLGGHNPPVIVIHGNQLD
ALPESYKRYLNNEFIKHLGLVGTPLKIEFKGGQNPFANKKNKLSQRQVNKKKRLMRWAKSKK

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain

Homologues:

Organism=Escherichia coli, GI87082120, Length=490, Percent_Identity=55.3061224489796, Blast_Score=558, Evalue=1e-160,
Organism=Escherichia coli, GI2367268, Length=95, Percent_Identity=34.7368421052632, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1788919, Length=177, Percent_Identity=27.683615819209, Blast_Score=64, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6323665, Length=179, Percent_Identity=29.608938547486, Blast_Score=79, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DER_LEGPA (Q5X522)

Other databases:

- EMBL:   CR628336
- RefSeq:   YP_123822.1
- HSSP:   O57939
- ProteinModelPortal:   Q5X522
- SMR:   Q5X522
- STRING:   Q5X522
- GeneID:   3117352
- GenomeReviews:   CR628336_GR
- KEGG:   lpp:lpp1498
- LegioList:   lpp1498
- eggNOG:   COG1160
- HOGENOM:   HBG592135
- OMA:   TRDRTYQ
- ProtClustDB:   PRK00093
- BioCyc:   LPNE297246:LPP1498-MONOMER
- GO:   GO:0005622
- HAMAP:   MF_00195
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- PIRSF:   PIRSF006485
- PRINTS:   PR00326
- TIGRFAMs:   TIGR03594
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01926 MMR_HSR1

EC number: NA

Molecular weight: Translated: 51311; Mature: 51311

Theoretical pI: Translated: 9.97; Mature: 9.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPVIALVGRPNVGKSTLFNRITKTQDALVADFPGLTRDRQYGHAQHENKSFIIVDTGGI
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCC
GVDDIEVDTLMSRQSQVALNEANVILFLVDGRSGLTGIDQQIAQALRKLNKKVHLVVNKT
CCCCCHHHHHHHCHHHEEEECCCEEEEEEECCCCCCHHHHHHHHHHHHCCCEEEEEEECC
DGMNEDIACADFQSLGITDVHAISASHGGGISSLLEEILEPFTTETHEATDDKAIKIAFA
CCCCCCCEECCHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEC
GRPNVGKSTLINRILGEERVVVYDMPGTTRDSISIPFTREDKQYVLIDTAGVRRKSRIDE
CCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCEECCEECCCCCEEEEECCCCCHHHHHHH
KIEKFSVIKTLQAIKEAHVCLLLLDANEGITDQDMNLLGFIIESGKALVIAVNKWDGLEE
HHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCHHHHHHCCCCCEEEEEEECCCCCCH
DHKEKIKSELSRRLHFANFAKIRFISALHGSGVGGLFKDINEAYHSAIQSFSTPKLTRLL
HHHHHHHHHHHHHHHHHHHHHHHEEHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHH
QDISAKHTPPCINGRRIKLRYAHLGGHNPPVIVIHGNQLDALPESYKRYLNNEFIKHLGL
HHHHCCCCCCCCCCCEEEEEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCC
VGTPLKIEFKGGQNPFANKKNKLSQRQVNKKKRLMRWAKSKK
CCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIPVIALVGRPNVGKSTLFNRITKTQDALVADFPGLTRDRQYGHAQHENKSFIIVDTGGI
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCC
GVDDIEVDTLMSRQSQVALNEANVILFLVDGRSGLTGIDQQIAQALRKLNKKVHLVVNKT
CCCCCHHHHHHHCHHHEEEECCCEEEEEEECCCCCCHHHHHHHHHHHHCCCEEEEEEECC
DGMNEDIACADFQSLGITDVHAISASHGGGISSLLEEILEPFTTETHEATDDKAIKIAFA
CCCCCCCEECCHHHCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEC
GRPNVGKSTLINRILGEERVVVYDMPGTTRDSISIPFTREDKQYVLIDTAGVRRKSRIDE
CCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCEECCEECCCCCEEEEECCCCCHHHHHHH
KIEKFSVIKTLQAIKEAHVCLLLLDANEGITDQDMNLLGFIIESGKALVIAVNKWDGLEE
HHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCHHHHHHCCCCCEEEEEEECCCCCCH
DHKEKIKSELSRRLHFANFAKIRFISALHGSGVGGLFKDINEAYHSAIQSFSTPKLTRLL
HHHHHHHHHHHHHHHHHHHHHHHEEHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHH
QDISAKHTPPCINGRRIKLRYAHLGGHNPPVIVIHGNQLDALPESYKRYLNNEFIKHLGL
HHHHCCCCCCCCCCCEEEEEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCC
VGTPLKIEFKGGQNPFANKKNKLSQRQVNKKKRLMRWAKSKK
CCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA