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The map label for this gene is lok

Identifier: 148359013

GI number: 148359013

Start: 1700482

End: 1702071

Strand: Direct

Name: lok

Synonym: LPC_0898

Alternate gene names: NA

Gene position: 1700482-1702071 (Clockwise)

Preceding gene: 148359011

Following gene: 148359017

Centisome position: 47.55

GC content: 36.16

Gene sequence:

>1590_bases
ATGCCTCGTACAATGTTTTTTTCCGTTGATGCAGCTAATCTCCAAAATTTACAAATTACAAATCGAAAAGCTTTTGCAGC
GTTGGAGAGTTATCTGAATGATAATGATTCACCAGGTGCCTGGAATAATAATCAAGGATACAAATATACTCATAAGGATG
TTACTTATTGCTTCTCATTTAATCAATCCTTAGTAAGACGCCCAAGAAAATCGGATCAAAAAAAACATACATTTGAAATT
TTTGACCCTAATAAGAACCCTTTAGGCAAGGGAGCGTACGGTATTGTCTATCCCATTTTAGGTGCAATTCAGTTTGAATT
TGGAACCGCAATTAAAAGACCACCAAAGAATAAATTAGTTAAAATACAAAACCATAGTGAACGCGATCAAAGTCATTCTG
TACTACGTGAATATCAAGGGCTTCTTCAATCAGGGCATATAGCGGTTAAACCGCCAATATTTGTAGAAAACAAAGAGAGT
AAATTCAGTTACTTGATTATGGAAAAAGCGGAGGGTATCGTTTTAGAGAAGTTTCTAAATCCCGTTAAGCGGCTTGATTT
GTCTGAAGAGGTACCCGAGCTTAATCTTATTAATCGGATTGAGATTACTTTTGCCATTTTAAAAGCAATTAAAGAACAGG
TGACGGATAAGCATTTGATTCATCGAGATATAAAACCAGGAAATATTATAATCGATTTTAGCAAGTCACCTCCGATAGCT
AAAGTAATCGATTTTGGTTTTGTGCTTAGGGCGTCAGAACAGGATTACCGTCGTTGTGGAACCCGAGCATACAGAGCGCC
CGAATCTTTCAATACCCAGGCATTGTACACAGCAAAAGCTGATGTTTGGTCAACAGGCAGGATATTAAGTTATTTGTGGG
GAGATAAATATACTAATTACTATATCTCTCGTGATAAGGGTTTGGACTACGTGATTGAGAAGTCAAGAAACGAACTACTC
TTCTCTGACCCAGAATTGGAACTCTATTTAACCAAGGAAGATAAAAGTAAAATCAGATCGTGCCTAAGCGCAATGCTTAT
AGTTGACCCTGAGGAAAGAGGATCTATAGATAAGGCTATCAAACAGTTTTCCCAAATTGATTTTGAAAAATATAAAAGAT
TAAAGCGCTCTACAAATTTTGAAATTGATTTAACAGATAATGATATTAAATTAAGAAAACAGCTCAATTCAATTCACCTG
CATTTGATTACCCTACAGGGCAAAGAAAAAGATTTGCGTGATAGAGCATGTTTTGATGCAGCGAATGCAATGAGCCAATT
GGTTAGTAAGCTCTCTACCTACACCAATTATCTTGAAAAAAATCCAGATCCATTTTTAATAAAACGTTATAAAGAGTGCT
GCATCGCAGAAATAGATTTAGCTAATTTGGCTTTGCAAAATCACCGAGATGCTTTATGGTTGGTGGCTGAGTTATCAACT
GCTATCCTTTTGCTTGGTATAGGGTATTTATTTGCTTTTGGGATAAATTATTACTACACAGGTCGCCTGGGATTATTTTC
TCAAACCAGGTCTGAGAAATTGGTGGAAGAAATGAAAAGTTCGGTGTTAGGTATTGCGGTTGGAAATTAA

Upstream 100 bases:

>100_bases
AAAAATAATGAATTAGATTTTAGCTAAGAGTTCAATTAATTTAACTTAATAAAAAAGACGAGGTATAATAAAACCGATTA
ATCAAATTGAAGTCAATATC

Downstream 100 bases:

>100_bases
AAATCTGTATTTCCCGGATTATAACAGAGCTGTCTAATCCGGGTTATTCATGGTTAGATTCTTAACACTTGAGATTGAGC
CATATTCAGGTTTTCTAATT

Product: serine/threonine-protein kinase

Products: NA

Alternate protein names: Serine/Threonine Protein Kinase; Serine Threonin Protein Kinase

Number of amino acids: Translated: 529; Mature: 528

Protein sequence:

>529_residues
MPRTMFFSVDAANLQNLQITNRKAFAALESYLNDNDSPGAWNNNQGYKYTHKDVTYCFSFNQSLVRRPRKSDQKKHTFEI
FDPNKNPLGKGAYGIVYPILGAIQFEFGTAIKRPPKNKLVKIQNHSERDQSHSVLREYQGLLQSGHIAVKPPIFVENKES
KFSYLIMEKAEGIVLEKFLNPVKRLDLSEEVPELNLINRIEITFAILKAIKEQVTDKHLIHRDIKPGNIIIDFSKSPPIA
KVIDFGFVLRASEQDYRRCGTRAYRAPESFNTQALYTAKADVWSTGRILSYLWGDKYTNYYISRDKGLDYVIEKSRNELL
FSDPELELYLTKEDKSKIRSCLSAMLIVDPEERGSIDKAIKQFSQIDFEKYKRLKRSTNFEIDLTDNDIKLRKQLNSIHL
HLITLQGKEKDLRDRACFDAANAMSQLVSKLSTYTNYLEKNPDPFLIKRYKECCIAEIDLANLALQNHRDALWLVAELST
AILLLGIGYLFAFGINYYYTGRLGLFSQTRSEKLVEEMKSSVLGIAVGN

Sequences:

>Translated_529_residues
MPRTMFFSVDAANLQNLQITNRKAFAALESYLNDNDSPGAWNNNQGYKYTHKDVTYCFSFNQSLVRRPRKSDQKKHTFEI
FDPNKNPLGKGAYGIVYPILGAIQFEFGTAIKRPPKNKLVKIQNHSERDQSHSVLREYQGLLQSGHIAVKPPIFVENKES
KFSYLIMEKAEGIVLEKFLNPVKRLDLSEEVPELNLINRIEITFAILKAIKEQVTDKHLIHRDIKPGNIIIDFSKSPPIA
KVIDFGFVLRASEQDYRRCGTRAYRAPESFNTQALYTAKADVWSTGRILSYLWGDKYTNYYISRDKGLDYVIEKSRNELL
FSDPELELYLTKEDKSKIRSCLSAMLIVDPEERGSIDKAIKQFSQIDFEKYKRLKRSTNFEIDLTDNDIKLRKQLNSIHL
HLITLQGKEKDLRDRACFDAANAMSQLVSKLSTYTNYLEKNPDPFLIKRYKECCIAEIDLANLALQNHRDALWLVAELST
AILLLGIGYLFAFGINYYYTGRLGLFSQTRSEKLVEEMKSSVLGIAVGN
>Mature_528_residues
PRTMFFSVDAANLQNLQITNRKAFAALESYLNDNDSPGAWNNNQGYKYTHKDVTYCFSFNQSLVRRPRKSDQKKHTFEIF
DPNKNPLGKGAYGIVYPILGAIQFEFGTAIKRPPKNKLVKIQNHSERDQSHSVLREYQGLLQSGHIAVKPPIFVENKESK
FSYLIMEKAEGIVLEKFLNPVKRLDLSEEVPELNLINRIEITFAILKAIKEQVTDKHLIHRDIKPGNIIIDFSKSPPIAK
VIDFGFVLRASEQDYRRCGTRAYRAPESFNTQALYTAKADVWSTGRILSYLWGDKYTNYYISRDKGLDYVIEKSRNELLF
SDPELELYLTKEDKSKIRSCLSAMLIVDPEERGSIDKAIKQFSQIDFEKYKRLKRSTNFEIDLTDNDIKLRKQLNSIHLH
LITLQGKEKDLRDRACFDAANAMSQLVSKLSTYTNYLEKNPDPFLIKRYKECCIAEIDLANLALQNHRDALWLVAELSTA
ILLLGIGYLFAFGINYYYTGRLGLFSQTRSEKLVEEMKSSVLGIAVGN

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI5031689, Length=211, Percent_Identity=32.2274881516588, Blast_Score=67, Evalue=6e-11,
Organism=Drosophila melanogaster, GI17137306, Length=310, Percent_Identity=28.0645161290323, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24585370, Length=310, Percent_Identity=28.0645161290323, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI17137304, Length=310, Percent_Identity=28.0645161290323, Blast_Score=73, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 60814; Mature: 60683

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: PS50012 RCC1_3 ; PS00107 PROTEIN_KINASE_ATP ; PS00108 PROTEIN_KINASE_ST ; PS50011 PROTEIN_KINASE_DOM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRTMFFSVDAANLQNLQITNRKAFAALESYLNDNDSPGAWNNNQGYKYTHKDVTYCFSF
CCCEEEEEECCCCCCCEEECCHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCEEEEEEC
NQSLVRRPRKSDQKKHTFEIFDPNKNPLGKGAYGIVYPILGAIQFEFGTAIKRPPKNKLV
CHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHEEHHCCCCCCCCCCCEE
KIQNHSERDQSHSVLREYQGLLQSGHIAVKPPIFVENKESKFSYLIMEKAEGIVLEKFLN
EECCCCCCHHHHHHHHHHHHHHHCCCEEECCCEEEECCCCCEEEEEEECCCCCHHHHHHH
PVKRLDLSEEVPELNLINRIEITFAILKAIKEQVTDKHLIHRDIKPGNIIIDFSKSPPIA
HHHHCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHH
KVIDFGFVLRASEQDYRRCGTRAYRAPESFNTQALYTAKADVWSTGRILSYLWGDKYTNY
HHHCCHHEEECCCHHHHHHCCHHHCCCCCCCCCEEEEECCCCCCCHHHHHHHHCCCCCCE
YISRDKGLDYVIEKSRNELLFSDPELELYLTKEDKSKIRSCLSAMLIVDPEERGSIDKAI
EEECCCCCHHHHHCCCCCEEECCCCEEEEEECCHHHHHHHHHHHHEEECCHHCCCHHHHH
KQFSQIDFEKYKRLKRSTNFEIDLTDNDIKLRKQLNSIHLHLITLQGKEKDLRDRACFDA
HHHHHCCHHHHHHHHHCCCCEEEECCCHHHHHHHHCCEEEEEEEEECCCCHHHHHHHHHH
ANAMSQLVSKLSTYTNYLEKNPDPFLIKRYKECCIAEIDLANLALQNHRDALWLVAELST
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHCCCCCEEHHHHHHH
AILLLGIGYLFAFGINYYYTGRLGLFSQTRSEKLVEEMKSSVLGIAVGN
HHHHHHHHHHHHHCCCEEEECCEECHHHHHHHHHHHHHHHCEEEEEECC
>Mature Secondary Structure 
PRTMFFSVDAANLQNLQITNRKAFAALESYLNDNDSPGAWNNNQGYKYTHKDVTYCFSF
CCEEEEEECCCCCCCEEECCHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCEEEEEEC
NQSLVRRPRKSDQKKHTFEIFDPNKNPLGKGAYGIVYPILGAIQFEFGTAIKRPPKNKLV
CHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHEEHHCCCCCCCCCCCEE
KIQNHSERDQSHSVLREYQGLLQSGHIAVKPPIFVENKESKFSYLIMEKAEGIVLEKFLN
EECCCCCCHHHHHHHHHHHHHHHCCCEEECCCEEEECCCCCEEEEEEECCCCCHHHHHHH
PVKRLDLSEEVPELNLINRIEITFAILKAIKEQVTDKHLIHRDIKPGNIIIDFSKSPPIA
HHHHCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHH
KVIDFGFVLRASEQDYRRCGTRAYRAPESFNTQALYTAKADVWSTGRILSYLWGDKYTNY
HHHCCHHEEECCCHHHHHHCCHHHCCCCCCCCCEEEEECCCCCCCHHHHHHHHCCCCCCE
YISRDKGLDYVIEKSRNELLFSDPELELYLTKEDKSKIRSCLSAMLIVDPEERGSIDKAI
EEECCCCCHHHHHCCCCCEEECCCCEEEEEECCHHHHHHHHHHHHEEECCHHCCCHHHHH
KQFSQIDFEKYKRLKRSTNFEIDLTDNDIKLRKQLNSIHLHLITLQGKEKDLRDRACFDA
HHHHHCCHHHHHHHHHCCCCEEEECCCHHHHHHHHCCEEEEEEEEECCCCHHHHHHHHHH
ANAMSQLVSKLSTYTNYLEKNPDPFLIKRYKECCIAEIDLANLALQNHRDALWLVAELST
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHCCCCCEEHHHHHHH
AILLLGIGYLFAFGINYYYTGRLGLFSQTRSEKLVEEMKSSVLGIAVGN
HHHHHHHHHHHHHCCCEEEECCEECHHHHHHHHHHHHHHHCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA