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The map label for this gene is dtpA [H]

Identifier: 148358909

GI number: 148358909

Start: 1589309

End: 1590751

Strand: Reverse

Name: dtpA [H]

Synonym: LPC_0794

Alternate gene names: 148358909

Gene position: 1590751-1589309 (Counterclockwise)

Preceding gene: 148358916

Following gene: 148358908

Centisome position: 44.48

GC content: 36.66

Gene sequence:

>1443_bases
ATGGAAAAACACCCAAAATCTCTCCGCATCTACTTTACAACCGAAATGTGGGAACGTTATGGCTTTTACGCAGTTCAATC
CTTATTAGCACTTTATTTGGCCTTACACTTTAAATGGCCGGACAAAGAAATCTATTCTTTAGTAGGCTCGTTCACAGCAC
TCACCTACCTCTCACCATTAGTAGGAGGCTGGATTGCTGATAAATTAATAGGCCAAAAACGTGCTATATTGCTGGGTGCT
ATTGTTCTGTTTTTAAGTTATTGCATGTTGTCATTGATTGATAATTCTCTGGCATTAACCTCTTCACTTGCAGGAGTAGC
TGTAGGAACAGGTTTATTAAAACCTAACATTTCTTCATTACTAGGTAATGAATATCCAGTTGGCTCAACAAAAAGAGAAA
GTGGTTTTACTATTTTTTATATGGGCATCACGACAGGAATAATCCTCGGAACAACATTGCCAAGCAAGTTTAGTGAGTAT
TTTGGCTGGTCTGCTTCCTTCACCAGTGCATCAATCGGGCTAATCATCGCATTTGTAGTGTTTTTATTTGGAATACATCA
GTACAAAATTAAGGATTATAATCCTTTTGTTTTCCAACCAGGTAAAATCATTTCAGCTTTTGTGTTATTGGTTTTTCTGT
GGTCATTGTCATTTTATATTTTAAGTTCACCTCAGCTGGCGAATATCATGTTTGGACTTGTAGTTCTTTTTTCAGCCAGT
TACATTTTATATTCAGTAAATCGTGAAAGTGCAAATCAATCCAGGCAAACATTAGTTATCGGGTTATTATGCATCATCTC
TGTTATTTTCTGGGCATTTTATTTTCAGATGTTCATGTCTTTAACATTATTTATTGCGCGAGTAGTCGAGCCAAGCTTTT
TAGGTATGGATTTCCCGCCACCATACTACATCACAGTACAAAGTATTGGCATGTTAATAATTGGTTATTTTCTTGCCAAA
AGACACCATAATCTTACAATGATTGAAAGAGGCTTAAGTACCGGGAAAAAGTTTGTACTTGCTATGGTATTCATGACTCT
CGCCTACTCAATTATTGCCTTTGTAAGTACTGTAGTTGATAAATCTATTTTGATTTCACCTCTTCTTATCATCCCTGCCT
ATCTGATGATTTCTTTGGCTGAATTACTGCTTTCCCCAGTAGGATTGTCAGCAATCACTGTACTTGCTGACAAAAACAAG
GTAAGCACCATGATGGGTATCTTTTTCGTTTCATTAGGAATAGGAGGATTCCTTTCAGGGAAATTAGCTGATCTGACAGC
CATCCCTACTGGAGAGACAAATATAATCGTTTTAAAAACACTATATGCTACAGCATTCACCCAACAACTCAGCATATTGT
TCATTGCTACATTGGGCTGCCTGGTATTGTTTGCTGTGATTAAATTTTTATTGACCCATATTCAGATATGCGAAAAACAA
TAA

Upstream 100 bases:

>100_bases
GAGAAAAACCAGATAAAATGACCAATCAATATTCATACTGTTTTTTATATGATATAATTTTTATTTAATAAATTAATTTA
ATCGTAGTTACTTAAATAAT

Downstream 100 bases:

>100_bases
TTAGATTTTTACGTTTTAGTTTTCCAGGCCTGGAAAACTAAAACTCTTTTTATACAAATCAATTGTTGATATTATTCAAC
CCTTTTGACGGAATATATCT

Product: POT family transporter protein proton/peptide symporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 480; Mature: 480

Protein sequence:

>480_residues
MEKHPKSLRIYFTTEMWERYGFYAVQSLLALYLALHFKWPDKEIYSLVGSFTALTYLSPLVGGWIADKLIGQKRAILLGA
IVLFLSYCMLSLIDNSLALTSSLAGVAVGTGLLKPNISSLLGNEYPVGSTKRESGFTIFYMGITTGIILGTTLPSKFSEY
FGWSASFTSASIGLIIAFVVFLFGIHQYKIKDYNPFVFQPGKIISAFVLLVFLWSLSFYILSSPQLANIMFGLVVLFSAS
YILYSVNRESANQSRQTLVIGLLCIISVIFWAFYFQMFMSLTLFIARVVEPSFLGMDFPPPYYITVQSIGMLIIGYFLAK
RHHNLTMIERGLSTGKKFVLAMVFMTLAYSIIAFVSTVVDKSILISPLLIIPAYLMISLAELLLSPVGLSAITVLADKNK
VSTMMGIFFVSLGIGGFLSGKLADLTAIPTGETNIIVLKTLYATAFTQQLSILFIATLGCLVLFAVIKFLLTHIQICEKQ

Sequences:

>Translated_480_residues
MEKHPKSLRIYFTTEMWERYGFYAVQSLLALYLALHFKWPDKEIYSLVGSFTALTYLSPLVGGWIADKLIGQKRAILLGA
IVLFLSYCMLSLIDNSLALTSSLAGVAVGTGLLKPNISSLLGNEYPVGSTKRESGFTIFYMGITTGIILGTTLPSKFSEY
FGWSASFTSASIGLIIAFVVFLFGIHQYKIKDYNPFVFQPGKIISAFVLLVFLWSLSFYILSSPQLANIMFGLVVLFSAS
YILYSVNRESANQSRQTLVIGLLCIISVIFWAFYFQMFMSLTLFIARVVEPSFLGMDFPPPYYITVQSIGMLIIGYFLAK
RHHNLTMIERGLSTGKKFVLAMVFMTLAYSIIAFVSTVVDKSILISPLLIIPAYLMISLAELLLSPVGLSAITVLADKNK
VSTMMGIFFVSLGIGGFLSGKLADLTAIPTGETNIIVLKTLYATAFTQQLSILFIATLGCLVLFAVIKFLLTHIQICEKQ
>Mature_480_residues
MEKHPKSLRIYFTTEMWERYGFYAVQSLLALYLALHFKWPDKEIYSLVGSFTALTYLSPLVGGWIADKLIGQKRAILLGA
IVLFLSYCMLSLIDNSLALTSSLAGVAVGTGLLKPNISSLLGNEYPVGSTKRESGFTIFYMGITTGIILGTTLPSKFSEY
FGWSASFTSASIGLIIAFVVFLFGIHQYKIKDYNPFVFQPGKIISAFVLLVFLWSLSFYILSSPQLANIMFGLVVLFSAS
YILYSVNRESANQSRQTLVIGLLCIISVIFWAFYFQMFMSLTLFIARVVEPSFLGMDFPPPYYITVQSIGMLIIGYFLAK
RHHNLTMIERGLSTGKKFVLAMVFMTLAYSIIAFVSTVVDKSILISPLLIIPAYLMISLAELLLSPVGLSAITVLADKNK
VSTMMGIFFVSLGIGGFLSGKLADLTAIPTGETNIIVLKTLYATAFTQQLSILFIATLGCLVLFAVIKFLLTHIQICEKQ

Specific function: Proton-dependent permease that transports di- and tripeptides [H]

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family. DtpA subfamily [H]

Homologues:

Organism=Homo sapiens, GI4827008, Length=396, Percent_Identity=23.4848484848485, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI226371746, Length=199, Percent_Identity=25.6281407035176, Blast_Score=69, Evalue=9e-12,
Organism=Escherichia coli, GI1787922, Length=457, Percent_Identity=28.0087527352298, Blast_Score=186, Evalue=3e-48,
Organism=Escherichia coli, GI1789911, Length=456, Percent_Identity=27.8508771929825, Blast_Score=170, Evalue=2e-43,
Organism=Escherichia coli, GI1786927, Length=448, Percent_Identity=29.4642857142857, Blast_Score=166, Evalue=4e-42,
Organism=Escherichia coli, GI1790572, Length=474, Percent_Identity=25.5274261603376, Blast_Score=153, Evalue=2e-38,
Organism=Drosophila melanogaster, GI24639585, Length=204, Percent_Identity=27.9411764705882, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24639583, Length=204, Percent_Identity=27.9411764705882, Blast_Score=79, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24639581, Length=204, Percent_Identity=27.9411764705882, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 53106; Mature: 53106

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKHPKSLRIYFTTEMWERYGFYAVQSLLALYLALHFKWPDKEIYSLVGSFTALTYLSPL
CCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
VGGWIADKLIGQKRAILLGAIVLFLSYCMLSLIDNSLALTSSLAGVAVGTGLLKPNISSL
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCHHHH
LGNEYPVGSTKRESGFTIFYMGITTGIILGTTLPSKFSEYFGWSASFTSASIGLIIAFVV
CCCCCCCCCCCCCCCCEEEEHHHHHHHHHCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHH
FLFGIHQYKIKDYNPFVFQPGKIISAFVLLVFLWSLSFYILSSPQLANIMFGLVVLFSAS
HHHCCHHEEECCCCCCEECCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCH
YILYSVNRESANQSRQTLVIGLLCIISVIFWAFYFQMFMSLTLFIARVVEPSFLGMDFPP
HHEEECCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCC
PYYITVQSIGMLIIGYFLAKRHHNLTMIERGLSTGKKFVLAMVFMTLAYSIIAFVSTVVD
CEEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KSILISPLLIIPAYLMISLAELLLSPVGLSAITVLADKNKVSTMMGIFFVSLGIGGFLSG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEECCHHHHHHHHHHHHHHCCCHHCCC
KLADLTAIPTGETNIIVLKTLYATAFTQQLSILFIATLGCLVLFAVIKFLLTHIQICEKQ
CHHHEEECCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEKHPKSLRIYFTTEMWERYGFYAVQSLLALYLALHFKWPDKEIYSLVGSFTALTYLSPL
CCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
VGGWIADKLIGQKRAILLGAIVLFLSYCMLSLIDNSLALTSSLAGVAVGTGLLKPNISSL
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCHHHH
LGNEYPVGSTKRESGFTIFYMGITTGIILGTTLPSKFSEYFGWSASFTSASIGLIIAFVV
CCCCCCCCCCCCCCCCEEEEHHHHHHHHHCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHH
FLFGIHQYKIKDYNPFVFQPGKIISAFVLLVFLWSLSFYILSSPQLANIMFGLVVLFSAS
HHHCCHHEEECCCCCCEECCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCH
YILYSVNRESANQSRQTLVIGLLCIISVIFWAFYFQMFMSLTLFIARVVEPSFLGMDFPP
HHEEECCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCC
PYYITVQSIGMLIIGYFLAKRHHNLTMIERGLSTGKKFVLAMVFMTLAYSIIAFVSTVVD
CEEEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KSILISPLLIIPAYLMISLAELLLSPVGLSAITVLADKNKVSTMMGIFFVSLGIGGFLSG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEECCHHHHHHHHHHHHHHCCCHHCCC
KLADLTAIPTGETNIIVLKTLYATAFTQQLSILFIATLGCLVLFAVIKFLLTHIQICEKQ
CHHHEEECCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA