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The map label for this gene is fliD [H]

Identifier: 148358870

GI number: 148358870

Start: 1544294

End: 1545919

Strand: Reverse

Name: fliD [H]

Synonym: LPC_0754

Alternate gene names: 148358870

Gene position: 1545919-1544294 (Counterclockwise)

Preceding gene: 148358871

Following gene: 148358869

Centisome position: 43.22

GC content: 38.62

Gene sequence:

>1626_bases
ATGGAACTCTCTTCACCAGGCGTAGGGTCAGGACTTGATGTAAAAAACCTGGTCGATGCGATAGTCACGGCAGAAATAAC
TCCATCGCAAGTGCGTCATGATAAACAGTTAAACAGTGTCAATACAGAGTTGTCGGCGCTTGGTCAATTAAAAAGCTATT
TAACTAACTTGCAAACTTCGTTAGCCAAGCTCTCCAGTCTTAGCCAATTCTACACTATGAAATCAACCATTAGTGATCCG
AATTACTTTTCCGCTACTCTGGGGACTGGCGCGACTAAAAATACTTATCAAATTGAAATACAAAAACTGGCGCAACAACA
CAGCCTTGCAAGCTCTTACATGACTAATACTGGAAGTGGAACAATAACCATAAATTTTGGAACCTATAACAGTGATAAAA
CCACTTTTACACCTAATCCTTCAGCTACGTCAGTCAATATAACCATTGCGCCTGGCAATGATAGCCTTGTTGCGGTACGA
GATGCCATTAATAATACTAATTCAGGAGTAACAGCCAGCATAGTTCAAGATAGCCAGGGCTCCAGGCTAACTATTACTTC
GTCAAAAACTGGCGAAAATTATGCCATGAAAATTAGTGGTGGAGTTGCCTCATTGAATTATGATCCTACCATGGGAGTGA
ATTCATTAACTGAAACAGTAGCGGCACAAAACAGTACTGTTAAAATTAACGGATTAACTTTGGTTCAAAGTTCTAATCAA
TTGAATGAGGCAATAACTGGGGTCACCATTGATCTAAAAAAAGCAGAGGTTGGGAAAGTTGTTACCTTAACTGTTGATGA
TAACAAAGATCAGCTCACAGGCTTAATCAACGAGTTCGTAAAACAATACAATGATACCATGACTTTTTTAACCAATTTAA
CTGGTTATAACAGTGAAACCAGGCAAGGAGGGGTATTTCAGGGCGATCCACAATTTCGTAATTTAAAACTTAATTTAAAT
AAGTGGGCAACTACCCCTTTGGCTAATCAAGAAGGGCCAATCCGCTCATTGGCAGATTTAGGAATAATCACCAATAAGCA
AGGATTACTGGAAATCAAGCAAGATAAGTATAAAGCAGCACTTGATAATCATTATAAAGAAATAGGAGCATTGTTTGCAA
AAACAGCCAAGGCTAATGATACTGGCGTAAACATCAAAGCCATTAATTCAACTGTCAAATCAGGTACCTATGATGTGGTG
TTGACTGAATTTACTCCTGGAGTCAGCATGTCTGGAACAATAGGAGGTTTATCTGCTACATCATCTGATGGCATTACATT
GACAGGAAGTGGTGATTTGAGTGGCCTGTCGATTAATGTATTTTCAGGGTCTGCCGGAGCCCGTGGACAAATAACTGTTA
CAGACGGTATTGCAGTCCAATTAAGTTCCTTGCTGGATACTTACATTGAAATTAAAGGCGATTTGGACCAGAGAAAAGAC
CAACTCAATAATCAAGTCAAGCAATTGAATAAAATACAAAACGAAATTGATATCAGACGCAAATCAATTGAAACTCGCTA
TTTAAAACAATTCACTGCTCTGGACACTCTACTCAGCCAATTACAAAGCACTAGTGTTTTTCTATCCCAGCAATTAGCCA
ATTTACCCCAATTAAAATTGAAATAA

Upstream 100 bases:

>100_bases
ATGATATTATTAGTGGTTCTATAGACAAGCATGTTTAATAATTTGAAATATTTATTAAAAATTTGACTAGAACAATAACA
ACATAGAAAAGGGATACTCT

Downstream 100 bases:

>100_bases
TAGGAGGTAATGAGAATGAAAAACCTATATTCACAAATTTCTAGCCAATACAAAGCCATAGAGCTACAAACTCGCATAGA
AACGGCCTCCCCTCATGAAC

Product: flagellar hook associated protein 2 FliD

Products: NA

Alternate protein names: HAP2; Filament cap protein [H]

Number of amino acids: Translated: 541; Mature: 541

Protein sequence:

>541_residues
MELSSPGVGSGLDVKNLVDAIVTAEITPSQVRHDKQLNSVNTELSALGQLKSYLTNLQTSLAKLSSLSQFYTMKSTISDP
NYFSATLGTGATKNTYQIEIQKLAQQHSLASSYMTNTGSGTITINFGTYNSDKTTFTPNPSATSVNITIAPGNDSLVAVR
DAINNTNSGVTASIVQDSQGSRLTITSSKTGENYAMKISGGVASLNYDPTMGVNSLTETVAAQNSTVKINGLTLVQSSNQ
LNEAITGVTIDLKKAEVGKVVTLTVDDNKDQLTGLINEFVKQYNDTMTFLTNLTGYNSETRQGGVFQGDPQFRNLKLNLN
KWATTPLANQEGPIRSLADLGIITNKQGLLEIKQDKYKAALDNHYKEIGALFAKTAKANDTGVNIKAINSTVKSGTYDVV
LTEFTPGVSMSGTIGGLSATSSDGITLTGSGDLSGLSINVFSGSAGARGQITVTDGIAVQLSSLLDTYIEIKGDLDQRKD
QLNNQVKQLNKIQNEIDIRRKSIETRYLKQFTALDTLLSQLQSTSVFLSQQLANLPQLKLK

Sequences:

>Translated_541_residues
MELSSPGVGSGLDVKNLVDAIVTAEITPSQVRHDKQLNSVNTELSALGQLKSYLTNLQTSLAKLSSLSQFYTMKSTISDP
NYFSATLGTGATKNTYQIEIQKLAQQHSLASSYMTNTGSGTITINFGTYNSDKTTFTPNPSATSVNITIAPGNDSLVAVR
DAINNTNSGVTASIVQDSQGSRLTITSSKTGENYAMKISGGVASLNYDPTMGVNSLTETVAAQNSTVKINGLTLVQSSNQ
LNEAITGVTIDLKKAEVGKVVTLTVDDNKDQLTGLINEFVKQYNDTMTFLTNLTGYNSETRQGGVFQGDPQFRNLKLNLN
KWATTPLANQEGPIRSLADLGIITNKQGLLEIKQDKYKAALDNHYKEIGALFAKTAKANDTGVNIKAINSTVKSGTYDVV
LTEFTPGVSMSGTIGGLSATSSDGITLTGSGDLSGLSINVFSGSAGARGQITVTDGIAVQLSSLLDTYIEIKGDLDQRKD
QLNNQVKQLNKIQNEIDIRRKSIETRYLKQFTALDTLLSQLQSTSVFLSQQLANLPQLKLK
>Mature_541_residues
MELSSPGVGSGLDVKNLVDAIVTAEITPSQVRHDKQLNSVNTELSALGQLKSYLTNLQTSLAKLSSLSQFYTMKSTISDP
NYFSATLGTGATKNTYQIEIQKLAQQHSLASSYMTNTGSGTITINFGTYNSDKTTFTPNPSATSVNITIAPGNDSLVAVR
DAINNTNSGVTASIVQDSQGSRLTITSSKTGENYAMKISGGVASLNYDPTMGVNSLTETVAAQNSTVKINGLTLVQSSNQ
LNEAITGVTIDLKKAEVGKVVTLTVDDNKDQLTGLINEFVKQYNDTMTFLTNLTGYNSETRQGGVFQGDPQFRNLKLNLN
KWATTPLANQEGPIRSLADLGIITNKQGLLEIKQDKYKAALDNHYKEIGALFAKTAKANDTGVNIKAINSTVKSGTYDVV
LTEFTPGVSMSGTIGGLSATSSDGITLTGSGDLSGLSINVFSGSAGARGQITVTDGIAVQLSSLLDTYIEIKGDLDQRKD
QLNNQVKQLNKIQNEIDIRRKSIETRYLKQFTALDTLLSQLQSTSVFLSQQLANLPQLKLK

Specific function: Required for the morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the

COG id: COG1345

COG function: function code N; Flagellar capping protein

Gene ontology:

Cell location: Secreted. Bacterial flagellum [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fliD family [H]

Homologues:

Organism=Escherichia coli, GI1788233, Length=550, Percent_Identity=28.7272727272727, Blast_Score=136, Evalue=4e-33,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010809
- InterPro:   IPR003481 [H]

Pfam domain/function: PF07195 FliD_C; PF02465 FliD_N [H]

EC number: NA

Molecular weight: Translated: 57881; Mature: 57881

Theoretical pI: Translated: 7.69; Mature: 7.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELSSPGVGSGLDVKNLVDAIVTAEITPSQVRHDKQLNSVNTELSALGQLKSYLTNLQTS
CCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAKLSSLSQFYTMKSTISDPNYFSATLGTGATKNTYQIEIQKLAQQHSLASSYMTNTGSG
HHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCE
TITINFGTYNSDKTTFTPNPSATSVNITIAPGNDSLVAVRDAINNTNSGVTASIVQDSQG
EEEEEECCCCCCCCEECCCCCCEEEEEEEECCCCCEEEEEHHCCCCCCCEEEEEEECCCC
SRLTITSSKTGENYAMKISGGVASLNYDPTMGVNSLTETVAAQNSTVKINGLTLVQSSNQ
CEEEEEECCCCCCEEEEEECCEEEECCCCCCCHHHHHHHHHCCCCEEEEEEEEEEECCCH
LNEAITGVTIDLKKAEVGKVVTLTVDDNKDQLTGLINEFVKQYNDTMTFLTNLTGYNSET
HHHHHCCEEEEEEECCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCEEEHHHCCCCCCCC
RQGGVFQGDPQFRNLKLNLNKWATTPLANQEGPIRSLADLGIITNKQGLLEIKQDKYKAA
CCCCCEECCCCCEEEEEEECCEECCCCCCCCCCHHHHHHCCEEECCCCCEEEHHHHHHHH
LDNHYKEIGALFAKTAKANDTGVNIKAINSTVKSGTYDVVLTEFTPGVSMSGTIGGLSAT
HHHHHHHHHHHHHHHCCCCCCCCEEEEECHHHCCCCEEEEEEECCCCCCCCCCCCCCCCC
SSDGITLTGSGDLSGLSINVFSGSAGARGQITVTDGIAVQLSSLLDTYIEIKGDLDQRKD
CCCCEEEECCCCCCEEEEEEEECCCCCCEEEEEECCHHHHHHHHHHHHHEECCCHHHHHH
QLNNQVKQLNKIQNEIDIRRKSIETRYLKQFTALDTLLSQLQSTSVFLSQQLANLPQLKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
K
C
>Mature Secondary Structure
MELSSPGVGSGLDVKNLVDAIVTAEITPSQVRHDKQLNSVNTELSALGQLKSYLTNLQTS
CCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAKLSSLSQFYTMKSTISDPNYFSATLGTGATKNTYQIEIQKLAQQHSLASSYMTNTGSG
HHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCCCE
TITINFGTYNSDKTTFTPNPSATSVNITIAPGNDSLVAVRDAINNTNSGVTASIVQDSQG
EEEEEECCCCCCCCEECCCCCCEEEEEEEECCCCCEEEEEHHCCCCCCCEEEEEEECCCC
SRLTITSSKTGENYAMKISGGVASLNYDPTMGVNSLTETVAAQNSTVKINGLTLVQSSNQ
CEEEEEECCCCCCEEEEEECCEEEECCCCCCCHHHHHHHHHCCCCEEEEEEEEEEECCCH
LNEAITGVTIDLKKAEVGKVVTLTVDDNKDQLTGLINEFVKQYNDTMTFLTNLTGYNSET
HHHHHCCEEEEEEECCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCEEEHHHCCCCCCCC
RQGGVFQGDPQFRNLKLNLNKWATTPLANQEGPIRSLADLGIITNKQGLLEIKQDKYKAA
CCCCCEECCCCCEEEEEEECCEECCCCCCCCCCHHHHHHCCEEECCCCCEEEHHHHHHHH
LDNHYKEIGALFAKTAKANDTGVNIKAINSTVKSGTYDVVLTEFTPGVSMSGTIGGLSAT
HHHHHHHHHHHHHHHCCCCCCCCEEEEECHHHCCCCEEEEEEECCCCCCCCCCCCCCCCC
SSDGITLTGSGDLSGLSINVFSGSAGARGQITVTDGIAVQLSSLLDTYIEIKGDLDQRKD
CCCCEEEECCCCCCEEEEEEEECCCCCCEEEEEECCHHHHHHHHHHHHHEECCCHHHHHH
QLNNQVKQLNKIQNEIDIRRKSIETRYLKQFTALDTLLSQLQSTSVFLSQQLANLPQLKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
K
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1527488; 9097040; 9278503; 2659972; 6305924 [H]