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The map label for this gene is yceE [C]

Identifier: 148358856

GI number: 148358856

Start: 1527605

End: 1528819

Strand: Reverse

Name: yceE [C]

Synonym: LPC_0739

Alternate gene names: 148358856

Gene position: 1528819-1527605 (Counterclockwise)

Preceding gene: 148358857

Following gene: 148358855

Centisome position: 42.75

GC content: 38.6

Gene sequence:

>1215_bases
ATGAATAAACCAGTTCAAAAAATGATGCTCTCAGGTCAGTTTTTGATGATATTGGCCTTGGAAATGACGAATCCTTTTCT
ACCACTATTGATCGCGCACCAAAGCAACACACCAGTACCATCGGTAGTGATTTATAACACGCTGAGTCTAATTCTGCCGA
TGCTGGCTAACATTCTATTAACCCCAATCTGGGGCTTGGTAGCTGATCGATATGGCTATAAACCCATGTTAATGAGAGCA
TCCTGGGCCTTGGTGTTGACCCAAGCCAGTATGATTTTTGTAAATTCTGTATTCTGGATTTTAATCATCCGATTACTGCA
AGGAGCTTTTGCAGGTTTTCTTGTTGCAATGCAAACCTATGCCCTAAGTATTACTGAATGGCAAAACAAAAGCACACAAT
TATCTCGCTTGCAATCCTCCAAGGCAATTGCCACATCTACAGCCGGGTTTCTCGGAGGATTAGCTTTAAGCTTCACTAAC
TATCAAGGATTATTTGGTTTGGCAACATTGATATGCCTGGGCACTACTGTAGCGATGCACTACAAATTACCCTCGCCACC
AAAGCACCAGATAAAGAAAAAATCACAAACATTAAATCATTCTTACACATCAAAAAGTGTTTTCTTCTTTCTTTGCGTAT
TAATCATGCTAACCCAAATTGCCAAGTTTTTACCTGATCCAGGGTTTACCCTGTATCTAAATAAGTATTGTTCAAATAAT
CTGGTACTAATTGGATTTCTTTATTCTTTACCAGCAATGGGAATGCTATGTAGTTCAGTATGGTGTGGCAAACAGTTTGA
CTACTGTCGAAGTCAACCTTCTTTGGTTAACCAATATTTAATACGCTATAGTGTATTCGGAGCCATCCTCATGGTCATTC
AAGCCAATGTAGATAATTTCTATATGTTTGGCCTTATACGCATTTTGTGGGGAGTCGTACTTGCGGCTTTATTGCCCGCA
TTATTTGCTTTGTGCAGTGATCGTAATTTGTTACCAGGTTATGCCTTGGGCTTAGCCAATTCATTTGCAAAACTTGGAAA
TCTAATTGGATTGTTATTGGGTGGTCTTTTTGCATTTTATCTACCGTATCCTGCAATTTTTCTGATAATTGCCGGAATTT
ATAGTTTATTCGCAATTTTCGTTTACGGGTATGAACGGCTAAATGTCAGGCAGATGACAGATTTTTCTAATTCTTATTTT
AACGTGAAATCATGA

Upstream 100 bases:

>100_bases
TCTCTTCCCTGGCAACATAAAAGTTTGCTGAGCATGAGACTCAATCAAAATCAGGATAACCTGGTATTTTTTAGTCTTGA
CAACCCATTGAGCCAAGATA

Downstream 100 bases:

>100_bases
AAAAAAATGCTCTTCTTATAGTGTTATTAACCTGGTTTCTTGGAAACATGGATATACATTTCCTTACTCCAGCCTTGCCA
TCATTAGTTGATTACTTCTC

Product: multidrug resistance efflux pump

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MNKPVQKMMLSGQFLMILALEMTNPFLPLLIAHQSNTPVPSVVIYNTLSLILPMLANILLTPIWGLVADRYGYKPMLMRA
SWALVLTQASMIFVNSVFWILIIRLLQGAFAGFLVAMQTYALSITEWQNKSTQLSRLQSSKAIATSTAGFLGGLALSFTN
YQGLFGLATLICLGTTVAMHYKLPSPPKHQIKKKSQTLNHSYTSKSVFFFLCVLIMLTQIAKFLPDPGFTLYLNKYCSNN
LVLIGFLYSLPAMGMLCSSVWCGKQFDYCRSQPSLVNQYLIRYSVFGAILMVIQANVDNFYMFGLIRILWGVVLAALLPA
LFALCSDRNLLPGYALGLANSFAKLGNLIGLLLGGLFAFYLPYPAIFLIIAGIYSLFAIFVYGYERLNVRQMTDFSNSYF
NVKS

Sequences:

>Translated_404_residues
MNKPVQKMMLSGQFLMILALEMTNPFLPLLIAHQSNTPVPSVVIYNTLSLILPMLANILLTPIWGLVADRYGYKPMLMRA
SWALVLTQASMIFVNSVFWILIIRLLQGAFAGFLVAMQTYALSITEWQNKSTQLSRLQSSKAIATSTAGFLGGLALSFTN
YQGLFGLATLICLGTTVAMHYKLPSPPKHQIKKKSQTLNHSYTSKSVFFFLCVLIMLTQIAKFLPDPGFTLYLNKYCSNN
LVLIGFLYSLPAMGMLCSSVWCGKQFDYCRSQPSLVNQYLIRYSVFGAILMVIQANVDNFYMFGLIRILWGVVLAALLPA
LFALCSDRNLLPGYALGLANSFAKLGNLIGLLLGGLFAFYLPYPAIFLIIAGIYSLFAIFVYGYERLNVRQMTDFSNSYF
NVKS
>Mature_404_residues
MNKPVQKMMLSGQFLMILALEMTNPFLPLLIAHQSNTPVPSVVIYNTLSLILPMLANILLTPIWGLVADRYGYKPMLMRA
SWALVLTQASMIFVNSVFWILIIRLLQGAFAGFLVAMQTYALSITEWQNKSTQLSRLQSSKAIATSTAGFLGGLALSFTN
YQGLFGLATLICLGTTVAMHYKLPSPPKHQIKKKSQTLNHSYTSKSVFFFLCVLIMLTQIAKFLPDPGFTLYLNKYCSNN
LVLIGFLYSLPAMGMLCSSVWCGKQFDYCRSQPSLVNQYLIRYSVFGAILMVIQANVDNFYMFGLIRILWGVVLAALLPA
LFALCSDRNLLPGYALGLANSFAKLGNLIGLLLGGLFAFYLPYPAIFLIIAGIYSLFAIFVYGYERLNVRQMTDFSNSYF
NVKS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

Organism=Escherichia coli, GI1787291, Length=404, Percent_Identity=25.990099009901, Blast_Score=80, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 45031; Mature: 45031

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKPVQKMMLSGQFLMILALEMTNPFLPLLIAHQSNTPVPSVVIYNTLSLILPMLANILL
CCCHHHHHHHCCCHHHHEEHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHH
TPIWGLVADRYGYKPMLMRASWALVLTQASMIFVNSVFWILIIRLLQGAFAGFLVAMQTY
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALSITEWQNKSTQLSRLQSSKAIATSTAGFLGGLALSFTNYQGLFGLATLICLGTTVAMH
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHEE
YKLPSPPKHQIKKKSQTLNHSYTSKSVFFFLCVLIMLTQIAKFLPDPGFTLYLNKYCSNN
EECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHCCCC
LVLIGFLYSLPAMGMLCSSVWCGKQFDYCRSQPSLVNQYLIRYSVFGAILMVIQANVDNF
EEEEHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHH
YMFGLIRILWGVVLAALLPALFALCSDRNLLPGYALGLANSFAKLGNLIGLLLGGLFAFY
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPYPAIFLIIAGIYSLFAIFVYGYERLNVRQMTDFSNSYFNVKS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCEECCC
>Mature Secondary Structure
MNKPVQKMMLSGQFLMILALEMTNPFLPLLIAHQSNTPVPSVVIYNTLSLILPMLANILL
CCCHHHHHHHCCCHHHHEEHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHH
TPIWGLVADRYGYKPMLMRASWALVLTQASMIFVNSVFWILIIRLLQGAFAGFLVAMQTY
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALSITEWQNKSTQLSRLQSSKAIATSTAGFLGGLALSFTNYQGLFGLATLICLGTTVAMH
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHEE
YKLPSPPKHQIKKKSQTLNHSYTSKSVFFFLCVLIMLTQIAKFLPDPGFTLYLNKYCSNN
EECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHCCCC
LVLIGFLYSLPAMGMLCSSVWCGKQFDYCRSQPSLVNQYLIRYSVFGAILMVIQANVDNF
EEEEHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHH
YMFGLIRILWGVVLAALLPALFALCSDRNLLPGYALGLANSFAKLGNLIGLLLGGLFAFY
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPYPAIFLIIAGIYSLFAIFVYGYERLNVRQMTDFSNSYFNVKS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]