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The map label for this gene is etfD [C]

Identifier: 148358818

GI number: 148358818

Start: 1484445

End: 1486061

Strand: Reverse

Name: etfD [C]

Synonym: LPC_0701

Alternate gene names: 148358818

Gene position: 1486061-1484445 (Counterclockwise)

Preceding gene: 148358822

Following gene: 148358817

Centisome position: 41.55

GC content: 40.51

Gene sequence:

>1617_bases
ATGGAATTTGATGTTATCATAGTCGGTGCAGGGCCTTCTGGATTATCCGCTGCAATCAAATTAAAGCAACTGGCTTTAGC
TTCACAAAAAGAAATTACTATTTGTATACTGGAAAAAGGAGCTCAGGTCGGCGCTCATATTCTTTCTGGTGCAGTTTTAG
AACCCAGAAGCTTAAAAGAATTACTGCCAGAGAATTGGCAACAGGCCCCGCTAGATACTCCTGTTAACAAGGATCTGTTT
TATTTTTTGACTCAAAACAAATCATTTAAGCTCCCTACTCCAAAACCTATGCATAATGAAGGAAATTTCATTATCAGTTT
GGGAGAACTATGTAAGTTTCTTGCAGAACAAGCAGAAGCTCTAGGCTGTGAAATATACCCTGGATTTGCGGCAGCAGAAA
TTCTCTATAATGATAAAAATCAAGTCATAGGTGTAGCGACCGGGGACGTAGGAATTGATCGACAAGGAAAAAAAACTGAT
AATTATCAACCTGGCATGCATTTATTAGCCAAACAAACTTTATTTGCTGAGGGATGTCGCGGGCAATTAAGTCAAACATT
AATGAGTCGCTATCATTTAAGAGATCATTCGCAACCACAAACTTACGGTATAGGGATTAAAGAAATCTGGCAAGTTGATG
CATCCCGGCATGAACCTGGAAAAGTCATCCATACTGTTGGTTGGCCTCTTGATCATGCGACTTATGGAGGCTCCTTTTTG
TATCATCTTTCAGAGCAGAGAGTTGCTATAGGTTTTGTTGTAGGACTTGACTACAAGAACCCATGGTTAAATCCTTTTGG
AGAGTTTCAGAGATTTAAAACTCACCCCCTTATTAAATCTGTTCTAACAGGTGGTGAACGAATTGGTTATGGAGCCAGAG
CACTTAATGAGGGAGGATGGCAATCTCTCCCTAAACTTACCTTTCCTGGTGGCGCCTTGATTGGAGATGCTGCCGGTTTC
CTAAATGTGCCTAAAATCAAAGGAATTCACACCGCAATGCAATCTGGAATGCTTGCTGCACAAGCTTGCTTTGATGCGCT
AAGTGAGGAAAAGAATGGTCAATTTGAGCTAAGCGCTTACTCTGAAAAAATCAATCAATCCTGGCTAAAGCAAGAGCTAT
ATGCAGTGCGAAATATTCGACCGGGATTCAAATACGGTTTATTCCCCGGTCTAATTAATGCTGCCTTGGAAACTTATGTA
ACTCGAGGGTATTCTCCATGGACTTTAAAAAATCATGCGGACCATAAATCGTTAATTCCAGCAGAAAAAGCTAAAAAAAT
TAACTATCCCAAGCCCGATGGCGTGCTCACATTTGATAAACTCTCATCTGTATTTTTATCAAATACATTTCATGAAGAAA
ATCAACCCTGCCATCTCAAGTTAAAACAACCCAAACTGGCCATTGAAGTGAACTTAAACCAATACGCTTCCCCAGAAAGC
CGCTATTGCCCGGCAGCTGTTTATGAAATAATCGAGAATGTTGAAAAAGGGCCCCAATTACAAATTAATGCCCAGAACTG
TATTCATTGTAAAACGTGCGATATTAAAGATCCGCGTCAAAATATAGTTTGGCAAGCACCCGAAGGTGGGGGTGGACCGA
ATTACTCAGGAATGTAA

Upstream 100 bases:

>100_bases
CAAAAATTGAAAATATAAAATTTAATCTTGATCTTAAACCTTATAAAGGCGATCATTTTTTCATTTGTAAGTTAGAGGAG
TACGTGTGGAACACGAAACG

Downstream 100 bases:

>100_bases
CCAATCAATCTTAAATAATGTTTTTGGGTAGAGTCCTGTAATTATTAGCAGGGATGTTGATATAAAACATGAAAATAAGG
ATTATTGCATGTACCAGCCT

Product: electron transferring flavoprotein dehydrogenase

Products: NA

Alternate protein names: ETF-QO; ETF-ubiquinone oxidoreductase; Electron-transferring-flavoprotein dehydrogenase; ETF dehydrogenase [H]

Number of amino acids: Translated: 538; Mature: 538

Protein sequence:

>538_residues
MEFDVIIVGAGPSGLSAAIKLKQLALASQKEITICILEKGAQVGAHILSGAVLEPRSLKELLPENWQQAPLDTPVNKDLF
YFLTQNKSFKLPTPKPMHNEGNFIISLGELCKFLAEQAEALGCEIYPGFAAAEILYNDKNQVIGVATGDVGIDRQGKKTD
NYQPGMHLLAKQTLFAEGCRGQLSQTLMSRYHLRDHSQPQTYGIGIKEIWQVDASRHEPGKVIHTVGWPLDHATYGGSFL
YHLSEQRVAIGFVVGLDYKNPWLNPFGEFQRFKTHPLIKSVLTGGERIGYGARALNEGGWQSLPKLTFPGGALIGDAAGF
LNVPKIKGIHTAMQSGMLAAQACFDALSEEKNGQFELSAYSEKINQSWLKQELYAVRNIRPGFKYGLFPGLINAALETYV
TRGYSPWTLKNHADHKSLIPAEKAKKINYPKPDGVLTFDKLSSVFLSNTFHEENQPCHLKLKQPKLAIEVNLNQYASPES
RYCPAAVYEIIENVEKGPQLQINAQNCIHCKTCDIKDPRQNIVWQAPEGGGGPNYSGM

Sequences:

>Translated_538_residues
MEFDVIIVGAGPSGLSAAIKLKQLALASQKEITICILEKGAQVGAHILSGAVLEPRSLKELLPENWQQAPLDTPVNKDLF
YFLTQNKSFKLPTPKPMHNEGNFIISLGELCKFLAEQAEALGCEIYPGFAAAEILYNDKNQVIGVATGDVGIDRQGKKTD
NYQPGMHLLAKQTLFAEGCRGQLSQTLMSRYHLRDHSQPQTYGIGIKEIWQVDASRHEPGKVIHTVGWPLDHATYGGSFL
YHLSEQRVAIGFVVGLDYKNPWLNPFGEFQRFKTHPLIKSVLTGGERIGYGARALNEGGWQSLPKLTFPGGALIGDAAGF
LNVPKIKGIHTAMQSGMLAAQACFDALSEEKNGQFELSAYSEKINQSWLKQELYAVRNIRPGFKYGLFPGLINAALETYV
TRGYSPWTLKNHADHKSLIPAEKAKKINYPKPDGVLTFDKLSSVFLSNTFHEENQPCHLKLKQPKLAIEVNLNQYASPES
RYCPAAVYEIIENVEKGPQLQINAQNCIHCKTCDIKDPRQNIVWQAPEGGGGPNYSGM
>Mature_538_residues
MEFDVIIVGAGPSGLSAAIKLKQLALASQKEITICILEKGAQVGAHILSGAVLEPRSLKELLPENWQQAPLDTPVNKDLF
YFLTQNKSFKLPTPKPMHNEGNFIISLGELCKFLAEQAEALGCEIYPGFAAAEILYNDKNQVIGVATGDVGIDRQGKKTD
NYQPGMHLLAKQTLFAEGCRGQLSQTLMSRYHLRDHSQPQTYGIGIKEIWQVDASRHEPGKVIHTVGWPLDHATYGGSFL
YHLSEQRVAIGFVVGLDYKNPWLNPFGEFQRFKTHPLIKSVLTGGERIGYGARALNEGGWQSLPKLTFPGGALIGDAAGF
LNVPKIKGIHTAMQSGMLAAQACFDALSEEKNGQFELSAYSEKINQSWLKQELYAVRNIRPGFKYGLFPGLINAALETYV
TRGYSPWTLKNHADHKSLIPAEKAKKINYPKPDGVLTFDKLSSVFLSNTFHEENQPCHLKLKQPKLAIEVNLNQYASPES
RYCPAAVYEIIENVEKGPQLQINAQNCIHCKTCDIKDPRQNIVWQAPEGGGGPNYSGM

Specific function: Accepts electrons from ETF and reduces ubiquinone [H]

COG id: COG0644

COG function: function code C; Dehydrogenases (flavoproteins)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI119703746, Length=554, Percent_Identity=54.8736462093863, Blast_Score=610, Evalue=1e-175,
Organism=Escherichia coli, GI1787991, Length=394, Percent_Identity=26.3959390862944, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1786227, Length=384, Percent_Identity=25, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI87082155, Length=379, Percent_Identity=25.8575197889182, Blast_Score=89, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI25144720, Length=552, Percent_Identity=52.536231884058, Blast_Score=580, Evalue=1e-166,
Organism=Saccharomyces cerevisiae, GI6324932, Length=567, Percent_Identity=45.1499118165785, Blast_Score=506, Evalue=1e-144,
Organism=Drosophila melanogaster, GI24652256, Length=550, Percent_Identity=55.6363636363636, Blast_Score=619, Evalue=1e-177,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR007859
- InterPro:   IPR003042 [H]

Pfam domain/function: PF05187 ETF_QO [H]

EC number: =1.5.5.1 [H]

Molecular weight: Translated: 59448; Mature: 59448

Theoretical pI: Translated: 7.95; Mature: 7.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFDVIIVGAGPSGLSAAIKLKQLALASQKEITICILEKGAQVGAHILSGAVLEPRSLKE
CCEEEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHCCCCCCCHHHHH
LLPENWQQAPLDTPVNKDLFYFLTQNKSFKLPTPKPMHNEGNFIISLGELCKFLAEQAEA
HCCCCCCCCCCCCCCCCCEEEEEECCCEEECCCCCCCCCCCCEEEEHHHHHHHHHHHHHH
LGCEIYPGFAAAEILYNDKNQVIGVATGDVGIDRQGKKTDNYQPGMHLLAKQTLFAEGCR
CCCEECCCCEEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
GQLSQTLMSRYHLRDHSQPQTYGIGIKEIWQVDASRHEPGKVIHTVGWPLDHATYGGSFL
HHHHHHHHHHHHHCCCCCCCEECCCHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCEEE
YHLSEQRVAIGFVVGLDYKNPWLNPFGEFQRFKTHPLIKSVLTGGERIGYGARALNEGGW
EEECCCCEEEEEEEEECCCCCCCCCHHHHHHHHCCHHHHHHHCCCCCCCCCHHHCCCCCC
QSLPKLTFPGGALIGDAAGFLNVPKIKGIHTAMQSGMLAAQACFDALSEEKNGQFELSAY
CCCCCEECCCCCEEECCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEHHH
SEKINQSWLKQELYAVRNIRPGFKYGLFPGLINAALETYVTRGYSPWTLKNHADHKSLIP
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCC
AEKAKKINYPKPDGVLTFDKLSSVFLSNTFHEENQPCHLKLKQPKLAIEVNLNQYASPES
HHHHHCCCCCCCCCEEEHHHHHHHHHHCCCCCCCCCEEEEEECCEEEEEECCHHCCCCCC
RYCPAAVYEIIENVEKGPQLQINAQNCIHCKTCDIKDPRQNIVWQAPEGGGGPNYSGM
CCCHHHHHHHHHHHCCCCEEEEECCCCEEEEECCCCCCCCCCEEECCCCCCCCCCCCC
>Mature Secondary Structure
MEFDVIIVGAGPSGLSAAIKLKQLALASQKEITICILEKGAQVGAHILSGAVLEPRSLKE
CCEEEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHCCCCCCCHHHHH
LLPENWQQAPLDTPVNKDLFYFLTQNKSFKLPTPKPMHNEGNFIISLGELCKFLAEQAEA
HCCCCCCCCCCCCCCCCCEEEEEECCCEEECCCCCCCCCCCCEEEEHHHHHHHHHHHHHH
LGCEIYPGFAAAEILYNDKNQVIGVATGDVGIDRQGKKTDNYQPGMHLLAKQTLFAEGCR
CCCEECCCCEEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
GQLSQTLMSRYHLRDHSQPQTYGIGIKEIWQVDASRHEPGKVIHTVGWPLDHATYGGSFL
HHHHHHHHHHHHHCCCCCCCEECCCHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCEEE
YHLSEQRVAIGFVVGLDYKNPWLNPFGEFQRFKTHPLIKSVLTGGERIGYGARALNEGGW
EEECCCCEEEEEEEEECCCCCCCCCHHHHHHHHCCHHHHHHHCCCCCCCCCHHHCCCCCC
QSLPKLTFPGGALIGDAAGFLNVPKIKGIHTAMQSGMLAAQACFDALSEEKNGQFELSAY
CCCCCEECCCCCEEECCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHCCCCCCEEEHHH
SEKINQSWLKQELYAVRNIRPGFKYGLFPGLINAALETYVTRGYSPWTLKNHADHKSLIP
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCC
AEKAKKINYPKPDGVLTFDKLSSVFLSNTFHEENQPCHLKLKQPKLAIEVNLNQYASPES
HHHHHCCCCCCCCCEEEHHHHHHHHHHCCCCCCCCCEEEEEECCEEEEEECCHHCCCCCC
RYCPAAVYEIIENVEKGPQLQINAQNCIHCKTCDIKDPRQNIVWQAPEGGGGPNYSGM
CCCHHHHHHHHHHHCCCCEEEEECCCCEEEEECCCCCCCCCCEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]