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The map label for this gene is pqqL [C]

Identifier: 148358594

GI number: 148358594

Start: 3194649

End: 3195974

Strand: Direct

Name: pqqL [C]

Synonym: LPC_0467

Alternate gene names: 148358594

Gene position: 3194649-3195974 (Clockwise)

Preceding gene: 148358599

Following gene: 148358593

Centisome position: 89.32

GC content: 41.1

Gene sequence:

>1326_bases
GTGCACAAACCACTCATTTCTCTTATGATGCTACTCTCATTTCAGGCTTTTAGCCAAGTCCAGGAGTATACGTTAAACAA
TGGTTTAAAAGTACTGGTAAAAGAAGATCATCGAGCTCCAGTCGTAGTATCCATGATTTGGTATAACGTGGGTTCAGCAG
ATGAGCCTGTAGGCATCACTGGTGTTTCTCATGCCATAGAACACATGATGTTTAAAGGAACTTCCAAATACCCGGTAGGG
GTATTTTCCAAAACAATTGCTGCATTGGGAGGTCAGGAAAATGCTTTTACAAACAATGATTATACCGCCTATTATGAAAA
ATTAGATGCTGGTCATCTGGCTACAAGCTTCGAATTGGAAGCCGATCGCATGAATAATTTACTGCTTAATAGCGAGGAAT
TCGCTAAAGAAATTAAAGTCATTCAAGAGGAAAGACGTTTACGTACTGACAATAACCCGCAGGCACTTGCTTTCGAACGT
TTTCTGGCCACAGCGCATCTTACAGCGCCATACAATCACCCGGTGATAGGATGGATGAATGATTTGAAACAAATGAAAGT
AGAGGATTTAAAAAAATGGTACGAAAGTTATTACGCACCAAATAATGCCACCTTGGTAGTAGTAGGCGATGTGAATCCTG
AGAAAGTACATGCCTTGGCTGAACATTATTTCGGCTCAATAGCCAAACGTCCCATAGCGTCTCGTAAACCCCAGCAAGAA
CCCTCTGCGCTTGGGAAAAAAATGGTTTACATTAACGCGCCAGCGAAACTGCCATTACTGTTAATTGGCTATACTGTACC
TAGTGTAAAAACTGCTAAAAATAACTGGGAACCTTACGCCTTGGAAATTATCGCCGGGATACTTGATGCCGGGGAAAGTG
CGCGCTTTGCCAAACACCTGGTGCGAGGCAATCAAGTAGCCACTGGTGCAGAAGCCTATTATAACCTCTATTCAAGGTAC
CAAAGCCAATTTATTGTCTATGGGGCGCCTAGCCAAGATCATCAAATAAAAGATCTGGAAAAGGCATTAATTACGGAATT
GGAAGCCTTAAAAAAAGCGCCTGTTAGCAATCAGGAATTACAAAGAGTTAAAAATCAAATCATAGCACAAAAAACTTTTG
AAAAAGATTCTATTTTTGGTCAGGCCATGGAGCTGGGATTGTTAGAAACAATAGGCCTGGGTTGGAAAAATACGGAAACA
TACACCAAAGCCATCAATGAAATAACTCCCGAGCAAATTCAGCAAGTTGCGCAACGATATTTTCAAGAAAATAACATGAC
TGTTGCAGAATTAAAGCCAATCAGGCAAGAAGAGGTAAGACCATGA

Upstream 100 bases:

>100_bases
GGTTCGGAATTTTGATTTCGTTTAAACCATTTAATCATTTTAGTGTACAATTCCTTAAAAATATGAAATTCTATCATCTT
TTTAGCTTTGAGGTGACATT

Downstream 100 bases:

>100_bases
GTGTTTTAAGAGCTTTTATCATTTCGTTTAGTGTAATTTTTTCTCACAATCTATTCGCCAATTCATTCAAAACTGAAAAA
TGGCAGACTAAAAATGGGGT

Product: zinc protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 441

Protein sequence:

>441_residues
MHKPLISLMMLLSFQAFSQVQEYTLNNGLKVLVKEDHRAPVVVSMIWYNVGSADEPVGITGVSHAIEHMMFKGTSKYPVG
VFSKTIAALGGQENAFTNNDYTAYYEKLDAGHLATSFELEADRMNNLLLNSEEFAKEIKVIQEERRLRTDNNPQALAFER
FLATAHLTAPYNHPVIGWMNDLKQMKVEDLKKWYESYYAPNNATLVVVGDVNPEKVHALAEHYFGSIAKRPIASRKPQQE
PSALGKKMVYINAPAKLPLLLIGYTVPSVKTAKNNWEPYALEIIAGILDAGESARFAKHLVRGNQVATGAEAYYNLYSRY
QSQFIVYGAPSQDHQIKDLEKALITELEALKKAPVSNQELQRVKNQIIAQKTFEKDSIFGQAMELGLLETIGLGWKNTET
YTKAINEITPEQIQQVAQRYFQENNMTVAELKPIRQEEVRP

Sequences:

>Translated_441_residues
MHKPLISLMMLLSFQAFSQVQEYTLNNGLKVLVKEDHRAPVVVSMIWYNVGSADEPVGITGVSHAIEHMMFKGTSKYPVG
VFSKTIAALGGQENAFTNNDYTAYYEKLDAGHLATSFELEADRMNNLLLNSEEFAKEIKVIQEERRLRTDNNPQALAFER
FLATAHLTAPYNHPVIGWMNDLKQMKVEDLKKWYESYYAPNNATLVVVGDVNPEKVHALAEHYFGSIAKRPIASRKPQQE
PSALGKKMVYINAPAKLPLLLIGYTVPSVKTAKNNWEPYALEIIAGILDAGESARFAKHLVRGNQVATGAEAYYNLYSRY
QSQFIVYGAPSQDHQIKDLEKALITELEALKKAPVSNQELQRVKNQIIAQKTFEKDSIFGQAMELGLLETIGLGWKNTET
YTKAINEITPEQIQQVAQRYFQENNMTVAELKPIRQEEVRP
>Mature_441_residues
MHKPLISLMMLLSFQAFSQVQEYTLNNGLKVLVKEDHRAPVVVSMIWYNVGSADEPVGITGVSHAIEHMMFKGTSKYPVG
VFSKTIAALGGQENAFTNNDYTAYYEKLDAGHLATSFELEADRMNNLLLNSEEFAKEIKVIQEERRLRTDNNPQALAFER
FLATAHLTAPYNHPVIGWMNDLKQMKVEDLKKWYESYYAPNNATLVVVGDVNPEKVHALAEHYFGSIAKRPIASRKPQQE
PSALGKKMVYINAPAKLPLLLIGYTVPSVKTAKNNWEPYALEIIAGILDAGESARFAKHLVRGNQVATGAEAYYNLYSRY
QSQFIVYGAPSQDHQIKDLEKALITELEALKKAPVSNQELQRVKNQIIAQKTFEKDSIFGQAMELGLLETIGLGWKNTET
YTKAINEITPEQIQQVAQRYFQENNMTVAELKPIRQEEVRP

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI46593007, Length=215, Percent_Identity=27.906976744186, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI94538354, Length=222, Percent_Identity=28.8288288288288, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI155969707, Length=193, Percent_Identity=27.4611398963731, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1787770, Length=424, Percent_Identity=24.0566037735849, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI2367164, Length=224, Percent_Identity=26.3392857142857, Blast_Score=65, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17553678, Length=232, Percent_Identity=26.2931034482759, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71999683, Length=204, Percent_Identity=25.4901960784314, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI32566665, Length=249, Percent_Identity=25.3012048192771, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI25146563, Length=249, Percent_Identity=25.3012048192771, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI25146566, Length=249, Percent_Identity=25.3012048192771, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71994338, Length=249, Percent_Identity=25.3012048192771, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI72001443, Length=246, Percent_Identity=26.0162601626016, Blast_Score=67, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6323192, Length=358, Percent_Identity=23.1843575418994, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6323421, Length=302, Percent_Identity=22.5165562913907, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6325379, Length=222, Percent_Identity=27.9279279279279, Blast_Score=64, Evalue=5e-11,
Organism=Drosophila melanogaster, GI21357875, Length=435, Percent_Identity=24.5977011494253, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24646943, Length=435, Percent_Identity=24.5977011494253, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24667786, Length=222, Percent_Identity=27.4774774774775, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 49756; Mature: 49756

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKPLISLMMLLSFQAFSQVQEYTLNNGLKVLVKEDHRAPVVVSMIWYNVGSADEPVGIT
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEHCCCCCCCCCCCCC
GVSHAIEHMMFKGTSKYPVGVFSKTIAALGGQENAFTNNDYTAYYEKLDAGHLATSFELE
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCEEEEEEC
ADRMNNLLLNSEEFAKEIKVIQEERRLRTDNNPQALAFERFLATAHLTAPYNHPVIGWMN
HHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHH
DLKQMKVEDLKKWYESYYAPNNATLVVVGDVNPEKVHALAEHYFGSIAKRPIASRKPQQE
HHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCC
PSALGKKMVYINAPAKLPLLLIGYTVPSVKTAKNNWEPYALEIIAGILDAGESARFAKHL
HHHHCCEEEEEECCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHH
VRGNQVATGAEAYYNLYSRYQSQFIVYGAPSQDHQIKDLEKALITELEALKKAPVSNQEL
HCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHH
QRVKNQIIAQKTFEKDSIFGQAMELGLLETIGLGWKNTETYTKAINEITPEQIQQVAQRY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHH
FQENNMTVAELKPIRQEEVRP
HHHCCCCHHHHCCCHHHCCCC
>Mature Secondary Structure
MHKPLISLMMLLSFQAFSQVQEYTLNNGLKVLVKEDHRAPVVVSMIWYNVGSADEPVGIT
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEHCCCCCCCCCCCCC
GVSHAIEHMMFKGTSKYPVGVFSKTIAALGGQENAFTNNDYTAYYEKLDAGHLATSFELE
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCEEEEEEC
ADRMNNLLLNSEEFAKEIKVIQEERRLRTDNNPQALAFERFLATAHLTAPYNHPVIGWMN
HHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHH
DLKQMKVEDLKKWYESYYAPNNATLVVVGDVNPEKVHALAEHYFGSIAKRPIASRKPQQE
HHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCC
PSALGKKMVYINAPAKLPLLLIGYTVPSVKTAKNNWEPYALEIIAGILDAGESARFAKHL
HHHHCCEEEEEECCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHH
VRGNQVATGAEAYYNLYSRYQSQFIVYGAPSQDHQIKDLEKALITELEALKKAPVSNQEL
HCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHH
QRVKNQIIAQKTFEKDSIFGQAMELGLLETIGLGWKNTETYTKAINEITPEQIQQVAQRY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHH
FQENNMTVAELKPIRQEEVRP
HHHCCCCHHHHCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]