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The map label for this gene is surA [H]

Identifier: 148358511

GI number: 148358511

Start: 410163

End: 411452

Strand: Direct

Name: surA [H]

Synonym: LPC_0377

Alternate gene names: 148358511

Gene position: 410163-411452 (Clockwise)

Preceding gene: 148358510

Following gene: 148358512

Centisome position: 11.47

GC content: 38.91

Gene sequence:

>1290_bases
ATGTTTAAAAGAATAGCATTGGTATGCGCTTTGTTTTCAGGAATATGTTTCGCTGAAGGAAAGCAGCTGTTAGATAAAGT
GGTTGCTATAGTAAATGATAATGTCATTACTTCTAGCGAATTGAACGCTCAAGTCGAGCTATCTAAAAAGCAGATTATCG
CTCAAAATATGCAAATGCCAGATGAGTCTGTATTACGTAAGCAAGTATTGCAACATTTAATAGACGTAGATCTGGAAATG
CAAATGGCAAAACAAAATGGTATTACTATTGAAAACGCTGAAATTGATGAAGCGATAGAAAAAATAGCTGCTTCAAATCA
TCTAAATTTATCGCAAATGCGCGATGAAATTACAAAGCAAGGAATTAGCTGGCAAGAATACAGACAAAATATCCGTAAAG
AAATGCTGATTTCCAGGGTTCAGCAAAAGGCAGTAGGTAAAGATATCATTGTTACTAATGAGCAGGTGGAACAATACTTA
AAAACTGCAGGCCGCATAGAAAATTCTAACTTGACGTATCATTTAAAAAATATTGTTATCCCTTTAAGCGAAGAACCAAC
GACCAAACAGCTTCAAAGAGCTAAAATCGAGGCAGAAAACTTGTTAAATAAAATTAAAAAAGGTGAAGACTTTAGCCGTT
TGGCAATAGAAGAATCAAGTGGAGAGTTTGCACTGGAAGGTGGTGATTTGGGTGAGCGTCATTTGGCGGAGCTGCCTGAG
GTATTTGCCAAGGAAGTAGTACATATGAAAGTAGGTCAGGTGGCCGGCCCGATAAGAGCAGGAAATGGATTTCATTTGAT
CAAATTAGTAGCTGTTGGCGGCGAAAATCAGCGTCATGTGATCACTCAAACCCATGTCAGACATATACTGCTTAAGCCCG
ATGCCAGCATGGTGCCTTCTGAAGCAATTAAGCAAGTCAATAACATTTACCGGCAAATACAGTCAGGCAAAGATTTTGCT
CTTATGGCTAAACAATATTCACTCGATGCTGCCAGCGCAGTGAAAGGCGGTGATTTAGGATGGGTTAATCCTGGTGAATT
AGTTCCAGAGTTTGAAAAAACCATGAACAGTTTGCCATTACATAAAGTCAGTAAACCGGTAAAAACCCAGTACGGGTGGC
ATCTCATTGAAGTGATTGCACGCAGACAGAAGGATGATTCAGAAGCTTTTAAGAAGCAACAGGTCAGGCAATTTCTACAA
CAGCGTAAGTTTGTAGAGGCAGTGCAAAACTGGCAACAACATTTGCGTTCTCAAGCTTATATTAATATAGTTGATAAGGA
TTTAGCATGA

Upstream 100 bases:

>100_bases
ATCTTTTTTTTATGAGTTATGGTGTAAATTAAGCAAACTTGCTTGTATTTTGACAAAGAATAACATAAATTGCCCGAAAA
ATGTAAATGAGGATTATGGC

Downstream 100 bases:

>100_bases
ACCCACTGCTTATTAGTAGTGGAGAGCCTGCTGGAATTGGCCCAGACTTATGCCTGGCTTTGGCAGAAACCGATTTGCCC
GTAGTGATATTGGGAGATCT

Product: peptidyl-prolyl cis-trans isomerase SurA

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase surA; PPIase surA; Rotamase surA [H]

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MFKRIALVCALFSGICFAEGKQLLDKVVAIVNDNVITSSELNAQVELSKKQIIAQNMQMPDESVLRKQVLQHLIDVDLEM
QMAKQNGITIENAEIDEAIEKIAASNHLNLSQMRDEITKQGISWQEYRQNIRKEMLISRVQQKAVGKDIIVTNEQVEQYL
KTAGRIENSNLTYHLKNIVIPLSEEPTTKQLQRAKIEAENLLNKIKKGEDFSRLAIEESSGEFALEGGDLGERHLAELPE
VFAKEVVHMKVGQVAGPIRAGNGFHLIKLVAVGGENQRHVITQTHVRHILLKPDASMVPSEAIKQVNNIYRQIQSGKDFA
LMAKQYSLDAASAVKGGDLGWVNPGELVPEFEKTMNSLPLHKVSKPVKTQYGWHLIEVIARRQKDDSEAFKKQQVRQFLQ
QRKFVEAVQNWQQHLRSQAYINIVDKDLA

Sequences:

>Translated_429_residues
MFKRIALVCALFSGICFAEGKQLLDKVVAIVNDNVITSSELNAQVELSKKQIIAQNMQMPDESVLRKQVLQHLIDVDLEM
QMAKQNGITIENAEIDEAIEKIAASNHLNLSQMRDEITKQGISWQEYRQNIRKEMLISRVQQKAVGKDIIVTNEQVEQYL
KTAGRIENSNLTYHLKNIVIPLSEEPTTKQLQRAKIEAENLLNKIKKGEDFSRLAIEESSGEFALEGGDLGERHLAELPE
VFAKEVVHMKVGQVAGPIRAGNGFHLIKLVAVGGENQRHVITQTHVRHILLKPDASMVPSEAIKQVNNIYRQIQSGKDFA
LMAKQYSLDAASAVKGGDLGWVNPGELVPEFEKTMNSLPLHKVSKPVKTQYGWHLIEVIARRQKDDSEAFKKQQVRQFLQ
QRKFVEAVQNWQQHLRSQAYINIVDKDLA
>Mature_429_residues
MFKRIALVCALFSGICFAEGKQLLDKVVAIVNDNVITSSELNAQVELSKKQIIAQNMQMPDESVLRKQVLQHLIDVDLEM
QMAKQNGITIENAEIDEAIEKIAASNHLNLSQMRDEITKQGISWQEYRQNIRKEMLISRVQQKAVGKDIIVTNEQVEQYL
KTAGRIENSNLTYHLKNIVIPLSEEPTTKQLQRAKIEAENLLNKIKKGEDFSRLAIEESSGEFALEGGDLGERHLAELPE
VFAKEVVHMKVGQVAGPIRAGNGFHLIKLVAVGGENQRHVITQTHVRHILLKPDASMVPSEAIKQVNNIYRQIQSGKDFA
LMAKQYSLDAASAVKGGDLGWVNPGELVPEFEKTMNSLPLHKVSKPVKTQYGWHLIEVIARRQKDDSEAFKKQQVRQFLQ
QRKFVEAVQNWQQHLRSQAYINIVDKDLA

Specific function: Chaperone involved in the correct folding and assembly of outer membrane proteins. It recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Periplasm. Note=Is capable of associating with the outer membrane (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PpiC domains [H]

Homologues:

Organism=Escherichia coli, GI1786238, Length=424, Percent_Identity=35.8490566037736, Blast_Score=281, Evalue=8e-77,
Organism=Escherichia coli, GI1790211, Length=94, Percent_Identity=36.1702127659575, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023034
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 48491; Mature: 48491

Theoretical pI: Translated: 8.24; Mature: 8.24

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKRIALVCALFSGICFAEGKQLLDKVVAIVNDNVITSSELNAQVELSKKQIIAQNMQMP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHCCCC
DESVLRKQVLQHLIDVDLEMQMAKQNGITIENAEIDEAIEKIAASNHLNLSQMRDEITKQ
HHHHHHHHHHHHHHCCCHHHHHHHHCCCEEECCHHHHHHHHHHHCCCCCHHHHHHHHHHC
GISWQEYRQNIRKEMLISRVQQKAVGKDIIVTNEQVEQYLKTAGRIENSNLTYHLKNIVI
CCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHCCCCCCCCEEEEEEEEE
PLSEEPTTKQLQRAKIEAENLLNKIKKGEDFSRLAIEESSGEFALEGGDLGERHLAELPE
ECCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHEEECCCCCEEECCCCCCHHHHHHHHH
VFAKEVVHMKVGQVAGPIRAGNGFHLIKLVAVGGENQRHVITQTHVRHILLKPDASMVPS
HHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCCCEEHHHHHHHHEEECCCCCCCCH
EAIKQVNNIYRQIQSGKDFALMAKQYSLDAASAVKGGDLGWVNPGELVPEFEKTMNSLPL
HHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHCCCCCCCCCCCHHHCHHHHHHHHCCCH
HKVSKPVKTQYGWHLIEVIARRQKDDSEAFKKQQVRQFLQQRKFVEAVQNWQQHLRSQAY
HHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
INIVDKDLA
EEHHCCCCC
>Mature Secondary Structure
MFKRIALVCALFSGICFAEGKQLLDKVVAIVNDNVITSSELNAQVELSKKQIIAQNMQMP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHHHHHHCCCC
DESVLRKQVLQHLIDVDLEMQMAKQNGITIENAEIDEAIEKIAASNHLNLSQMRDEITKQ
HHHHHHHHHHHHHHCCCHHHHHHHHCCCEEECCHHHHHHHHHHHCCCCCHHHHHHHHHHC
GISWQEYRQNIRKEMLISRVQQKAVGKDIIVTNEQVEQYLKTAGRIENSNLTYHLKNIVI
CCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHCCCCCCCCEEEEEEEEE
PLSEEPTTKQLQRAKIEAENLLNKIKKGEDFSRLAIEESSGEFALEGGDLGERHLAELPE
ECCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHEEECCCCCEEECCCCCCHHHHHHHHH
VFAKEVVHMKVGQVAGPIRAGNGFHLIKLVAVGGENQRHVITQTHVRHILLKPDASMVPS
HHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCCCEEHHHHHHHHEEECCCCCCCCH
EAIKQVNNIYRQIQSGKDFALMAKQYSLDAASAVKGGDLGWVNPGELVPEFEKTMNSLPL
HHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHCCCCCCCCCCCHHHCHHHHHHHHCCCH
HKVSKPVKTQYGWHLIEVIARRQKDDSEAFKKQQVRQFLQQRKFVEAVQNWQQHLRSQAY
HHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
INIVDKDLA
EEHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA