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The map label for this gene is resA [H]

Identifier: 148358151

GI number: 148358151

Start: 14688

End: 15158

Strand: Reverse

Name: resA [H]

Synonym: LPC_0012

Alternate gene names: 148358151

Gene position: 15158-14688 (Counterclockwise)

Preceding gene: 148358152

Following gene: 148358148

Centisome position: 0.42

GC content: 37.37

Gene sequence:

>471_bases
ATGAAGCGCTTAATACCTACTTTCATATACCTGCTGGCTTTAGCAATTACTCCCTTCTCTACTCATGCAGAAGCGCTTTT
GAAAGACACCTTTGGCCACAATATTCCTTTTTCATCACTTAAAGGAAAATGGGTTTTTATCAACTATTGGGCAAGCTGGT
GTGAAACCTGTGTCGATGAAATCCCTGAGTTTAATCGCTTTTACAAAAACCATAAAAATGAGGCAGTAGCCCTATACGCA
GTCAATTACGATGCTCTTCCCTTACCAGAGCAAAAATTACTAATTAAAAAATTTAATATTAACTACCCTAATTTGTTAAA
GGATCCGGCCCAGGATTTACAATTAGGAGACATCACAGGAGTGCCTGTAACTTTTGTATTTAACCCAAAGGGGCAATTAA
TTAAAAAATTATACGGGGGACAAACGGCAAAAACATTAGAAAAAGTCATTGCAGAGAACAGAACCTCCTAA

Upstream 100 bases:

>100_bases
AAGTTAGTAAATTGGACATAAGCAAGTACATGCATTTTCTTATGTCCAATTTGGCTAACAATAATAACCGTAGACAATTT
TGACTATTCAAGAGGTGATC

Downstream 100 bases:

>100_bases
GAGAATAAATAAAAATTATATTTTTGGTCAATCAGTTAAAAATTTTATTGTGAATTTATCAAGTCCGGAATCGATTCTAT
CGCCCCGCAGCCTGACTTGA

Product: thiol-disulfide oxidoreductase ResA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 156; Mature: 156

Protein sequence:

>156_residues
MKRLIPTFIYLLALAITPFSTHAEALLKDTFGHNIPFSSLKGKWVFINYWASWCETCVDEIPEFNRFYKNHKNEAVALYA
VNYDALPLPEQKLLIKKFNINYPNLLKDPAQDLQLGDITGVPVTFVFNPKGQLIKKLYGGQTAKTLEKVIAENRTS

Sequences:

>Translated_156_residues
MKRLIPTFIYLLALAITPFSTHAEALLKDTFGHNIPFSSLKGKWVFINYWASWCETCVDEIPEFNRFYKNHKNEAVALYA
VNYDALPLPEQKLLIKKFNINYPNLLKDPAQDLQLGDITGVPVTFVFNPKGQLIKKLYGGQTAKTLEKVIAENRTS
>Mature_156_residues
MKRLIPTFIYLLALAITPFSTHAEALLKDTFGHNIPFSSLKGKWVFINYWASWCETCVDEIPEFNRFYKNHKNEAVALYA
VNYDALPLPEQKLLIKKFNINYPNLLKDPAQDLQLGDITGVPVTFVFNPKGQLIKKLYGGQTAKTLEKVIAENRTS

Specific function: Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c; following this reduction heme can be covalent

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein. Note=The thioredoxin-like motif is exposed on the outside of the membrane [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00578 AhpC-TSA [H]

EC number: NA

Molecular weight: Translated: 17808; Mature: 17808

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRLIPTFIYLLALAITPFSTHAEALLKDTFGHNIPFSSLKGKWVFINYWASWCETCVDE
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEHHHHHHHHHHHHH
IPEFNRFYKNHKNEAVALYAVNYDALPLPEQKLLIKKFNINYPNLLKDPAQDLQLGDITG
CHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHCCCCCCHHHCCCHHHCCCCCCCC
VPVTFVFNPKGQLIKKLYGGQTAKTLEKVIAENRTS
CCEEEEECCHHHHHHHHHCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKRLIPTFIYLLALAITPFSTHAEALLKDTFGHNIPFSSLKGKWVFINYWASWCETCVDE
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEHHHHHHHHHHHHH
IPEFNRFYKNHKNEAVALYAVNYDALPLPEQKLLIKKFNINYPNLLKDPAQDLQLGDITG
CHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHHCCCCCCHHHCCCHHHCCCCCCCC
VPVTFVFNPKGQLIKKLYGGQTAKTLEKVIAENRTS
CCEEEEECCHHHHHHHHHCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715; 12637552 [H]