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The map label for this gene is hflC [C]

Identifier: 148284989

GI number: 148284989

Start: 1752932

End: 1753882

Strand: Direct

Name: hflC [C]

Synonym: OTBS_1818

Alternate gene names: 148284989

Gene position: 1752932-1753882 (Clockwise)

Preceding gene: 148284986

Following gene: 148284995

Centisome position: 82.41

GC content: 34.7

Gene sequence:

>951_bases
ATGATATTAAGTATCAACATATTCGTGTTAGTTGCACTAGTTATTATACTATTTAATGTATTTAAAATTGTACCTCAGCA
ACAGGCTTGGATAATAGAAAGATTAGGTAAGCTACATAAAGTTTTGCCTGCAGGGTTAAATTTTATAATCCCAATGATAG
ATAGAGTAGCATACAAGCATACCTTAAAGGAACAAGCAATTGATGTAACTGCGCAAACAGCTATTTCTAACGATAATGTT
AGCTTATCTATTGATGGAGTACTATATGTTAAAATTATAGATCCAGTAGCAGCTTCTTATGGAGTTAGTGATCCATATTA
TGCGATTACTCAATTAGCTCAAACTACTATGCGATCAGAGATAGGAAAGATTCCACTAGATAAAACTTTTGAGGAACGTG
AAAATTTAAATATAGCTATTGTAACATCTATTAATCATGCAGCTGCAAACTGGGGAATTCAGTGTATGAGATATGAGATT
AAGGATATTTACCCTCCACAATCTGTATTACGAGCTATGGAGCTTCAGGTAGCAGCAGAAAGACAAAAACGTGCTCAAAT
ACTTGAATCAGAGGGAAAGAGGCAGTCGCAAATCAACCTAGCAGAAGCAGGAAAAGCAGAAGTGGTTTTAAATTCTGAAG
CTGCAAAAACCGATCAAGTTAATAGAGCTGTAGGTGAAGCTGAAGCTATATTACTAGTTGCAAAAGCTACAGCTGAAGGA
ATAGAGCGACTTGCGCAAGCAATAAATAATACAGGAGGAAGTGATGCTGTCTCGCTACGTATTGCAGAACAGTATATCGA
TGCTTTATCCAAAATAGCTAAAGAAACTAATACAGTAATTATACCATCAAACATTAATGACAGTAGTTCAGTAGTTACTC
AGGCTTTATCAATTTTTGATGCAATAAAACTTTCAAAGTCTAAAAAATCTACAAACTCAGAGAATGCATAG

Upstream 100 bases:

>100_bases
TATGCAATAACTATATGATATGGGACTGTATATCCTTGACAATATATCATAATTTATTAGAGTATAATAGCAAATTAATT
AATTCTGGGAAATAAAAATT

Downstream 100 bases:

>100_bases
CATAAGTACAATATGCAAAAAGTTTATTGATAGAACAGAAGTAAGCTATGGTAAGACTGCAACTAATCTAGTAATAATTA
GACTAAGAGGTATTATAGTT

Product: putative membrane protease, stomatin/prohibitin-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MILSINIFVLVALVIILFNVFKIVPQQQAWIIERLGKLHKVLPAGLNFIIPMIDRVAYKHTLKEQAIDVTAQTAISNDNV
SLSIDGVLYVKIIDPVAASYGVSDPYYAITQLAQTTMRSEIGKIPLDKTFEERENLNIAIVTSINHAAANWGIQCMRYEI
KDIYPPQSVLRAMELQVAAERQKRAQILESEGKRQSQINLAEAGKAEVVLNSEAAKTDQVNRAVGEAEAILLVAKATAEG
IERLAQAINNTGGSDAVSLRIAEQYIDALSKIAKETNTVIIPSNINDSSSVVTQALSIFDAIKLSKSKKSTNSENA

Sequences:

>Translated_316_residues
MILSINIFVLVALVIILFNVFKIVPQQQAWIIERLGKLHKVLPAGLNFIIPMIDRVAYKHTLKEQAIDVTAQTAISNDNV
SLSIDGVLYVKIIDPVAASYGVSDPYYAITQLAQTTMRSEIGKIPLDKTFEERENLNIAIVTSINHAAANWGIQCMRYEI
KDIYPPQSVLRAMELQVAAERQKRAQILESEGKRQSQINLAEAGKAEVVLNSEAAKTDQVNRAVGEAEAILLVAKATAEG
IERLAQAINNTGGSDAVSLRIAEQYIDALSKIAKETNTVIIPSNINDSSSVVTQALSIFDAIKLSKSKKSTNSENA
>Mature_316_residues
MILSINIFVLVALVIILFNVFKIVPQQQAWIIERLGKLHKVLPAGLNFIIPMIDRVAYKHTLKEQAIDVTAQTAISNDNV
SLSIDGVLYVKIIDPVAASYGVSDPYYAITQLAQTTMRSEIGKIPLDKTFEERENLNIAIVTSINHAAANWGIQCMRYEI
KDIYPPQSVLRAMELQVAAERQKRAQILESEGKRQSQINLAEAGKAEVVLNSEAAKTDQVNRAVGEAEAILLVAKATAEG
IERLAQAINNTGGSDAVSLRIAEQYIDALSKIAKETNTVIIPSNINDSSSVVTQALSIFDAIKLSKSKKSTNSENA

Specific function: Unknown

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family [H]

Homologues:

Organism=Homo sapiens, GI7305503, Length=288, Percent_Identity=54.8611111111111, Blast_Score=319, Evalue=2e-87,
Organism=Homo sapiens, GI21686995, Length=199, Percent_Identity=31.1557788944724, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI221316744, Length=199, Percent_Identity=31.1557788944724, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI38016911, Length=211, Percent_Identity=29.8578199052133, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI1786697, Length=310, Percent_Identity=34.8387096774194, Blast_Score=187, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI32564147, Length=293, Percent_Identity=52.901023890785, Blast_Score=326, Evalue=1e-89,
Organism=Caenorhabditis elegans, GI17569493, Length=188, Percent_Identity=31.9148936170213, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI193209764, Length=188, Percent_Identity=31.9148936170213, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17569497, Length=200, Percent_Identity=28.5, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17570161, Length=200, Percent_Identity=32, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI193210507, Length=200, Percent_Identity=32, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71989955, Length=160, Percent_Identity=32.5, Blast_Score=88, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI71989948, Length=159, Percent_Identity=32.7044025157233, Blast_Score=88, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17569499, Length=209, Percent_Identity=31.5789473684211, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71987612, Length=221, Percent_Identity=29.8642533936652, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI25153583, Length=221, Percent_Identity=29.8642533936652, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI32566490, Length=211, Percent_Identity=29.8578199052133, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI71987621, Length=221, Percent_Identity=29.8642533936652, Blast_Score=81, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17570459, Length=219, Percent_Identity=28.310502283105, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71989963, Length=120, Percent_Identity=34.1666666666667, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI45550506, Length=291, Percent_Identity=53.2646048109966, Blast_Score=315, Evalue=4e-86,
Organism=Drosophila melanogaster, GI28573263, Length=206, Percent_Identity=31.0679611650485, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI62484448, Length=216, Percent_Identity=33.3333333333333, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI62484274, Length=216, Percent_Identity=33.3333333333333, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI281365664, Length=216, Percent_Identity=33.3333333333333, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24657857, Length=216, Percent_Identity=33.3333333333333, Blast_Score=95, Evalue=5e-20,
Organism=Drosophila melanogaster, GI18860517, Length=203, Percent_Identity=33.9901477832512, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI45556022, Length=216, Percent_Identity=31.9444444444444, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI281361633, Length=198, Percent_Identity=28.2828282828283, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI281361631, Length=198, Percent_Identity=28.2828282828283, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI21356845, Length=198, Percent_Identity=26.7676767676768, Blast_Score=87, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR018080
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: NA

Molecular weight: Translated: 34527; Mature: 34527

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILSINIFVLVALVIILFNVFKIVPQQQAWIIERLGKLHKVLPAGLNFIIPMIDRVAYKH
CEEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLKEQAIDVTAQTAISNDNVSLSIDGVLYVKIIDPVAASYGVSDPYYAITQLAQTTMRSE
HHHHHHHHHHHHHHCCCCCEEEEECCEEEEEEECHHHHHCCCCCHHHHHHHHHHHHHHHH
IGKIPLDKTFEERENLNIAIVTSINHAAANWGIQCMRYEIKDIYPPQSVLRAMELQVAAE
HCCCCCCCCHHHHCCCCEEEEEECCHHHHHCCHHHHEEHHHHCCCHHHHHHHHHHHHHHH
RQKRAQILESEGKRQSQINLAEAGKAEVVLNSEAAKTDQVNRAVGEAEAILLVAKATAEG
HHHHHHHHHHCCCHHHHCCHHHCCCEEEEECCCCHHHHHHHHHHCCHHEEEEEEHHHHHH
IERLAQAINNTGGSDAVSLRIAEQYIDALSKIAKETNTVIIPSNINDSSSVVTQALSIFD
HHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHH
AIKLSKSKKSTNSENA
HHHHHCCCCCCCCCCC
>Mature Secondary Structure
MILSINIFVLVALVIILFNVFKIVPQQQAWIIERLGKLHKVLPAGLNFIIPMIDRVAYKH
CEEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLKEQAIDVTAQTAISNDNVSLSIDGVLYVKIIDPVAASYGVSDPYYAITQLAQTTMRSE
HHHHHHHHHHHHHHCCCCCEEEEECCEEEEEEECHHHHHCCCCCHHHHHHHHHHHHHHHH
IGKIPLDKTFEERENLNIAIVTSINHAAANWGIQCMRYEIKDIYPPQSVLRAMELQVAAE
HCCCCCCCCHHHHCCCCEEEEEECCHHHHHCCHHHHEEHHHHCCCHHHHHHHHHHHHHHH
RQKRAQILESEGKRQSQINLAEAGKAEVVLNSEAAKTDQVNRAVGEAEAILLVAKATAEG
HHHHHHHHHHCCCHHHHCCHHHCCCEEEEECCCCHHHHHHHHHHCCHHEEEEEEHHHHHH
IERLAQAINNTGGSDAVSLRIAEQYIDALSKIAKETNTVIIPSNINDSSSVVTQALSIFD
HHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHH
AIKLSKSKKSTNSENA
HHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]