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The map label for this gene is trpS [H]

Identifier: 148284435

GI number: 148284435

Start: 739629

End: 740636

Strand: Direct

Name: trpS [H]

Synonym: OTBS_0762

Alternate gene names: 148284435

Gene position: 739629-740636 (Clockwise)

Preceding gene: 148284433

Following gene: 148284436

Centisome position: 34.77

GC content: 29.76

Gene sequence:

>1008_bases
ATGTCCAAACGTATATTATCTGGTATACAGGTTACAGGAAAGCAGCATCTTGGCAATTATTTAGGATCTATACAGAAATG
GGTTCAAATGCAATCAAAATTTCAGTCCATATTTTTTCTTGCTAATCTACATTCAATTACTACTTCACAAGAATCATTGA
AACTAAGTGAGTCGATATTTAGTTCAGCTTGCATGCTTCTAGCATGCGGAATAAATCCCAAACAATCAATAATTTTTCTT
CAATCTGATGTTAAAGAACATTCAGAGCTTGCATGGATACTAAATTGCGTTACTCCACTTGGACAATTAAAACGAATGAC
TCAATTTAAAGATAAAACTATCAAATGCAGCTCAAATAATATCAACTTAGGATTGCTAGCATATCCTGTACTGATGGCTG
CAGATGTTCTGTTATATCAAGCAGATTTAGTACCAGTTGGGGCTGATCAAAAGCAACATTTAGAACTAGTAAGAGATATA
GTTAAAATAATCCATCATAAGTTTAATGATGATACCATTTTCAAGTTACCGGAACTATTTATAGATCATACAGCAGGAAA
AATCATGAGTCTAAAAGATGGCAGAAAAAAAATGAGTAAGTCAGATATCTCTGATTTTAGTAGAATTAATCTAACTGATT
CACAAGACGTTATTTTTAGAAAGTTGCAAAAAGCAAAAACTGATTGCTATACTCAAATCACATATGACCCTACAAGCAGA
CCAGAGATTTCTAATCTAATTAATATATTTGCTGCACTATCTAATAAAACCACTAATGATATAGTAAAAGAATATGAATA
TGCAGAATTAACTAAATTTAAAAAAGACTTAGCAATGTTAATTATTGATTGTCTTAACCCTATTTTGAAAGAATATAATA
ATTATATGAATAATTTAGATTATGTTAATCAAGTATTGATTACAGGGGCTAATCAGGCTAAAATAATAGCTGAAAAAACC
ATAACAAAAGTAAAACAAAAATTTGGACTACAAATTTTGTCAACATAA

Upstream 100 bases:

>100_bases
TTAATACTTCAAAATTAGAATTTAAAAAATTATTAATGCTAAAAACTTCAAATATGTTTATAATAAACACCATTTAAAAC
ATTTAAAGTCAGGTATATTA

Downstream 100 bases:

>100_bases
ATATGATATCTAAATCTAAAACTAAATATGCTTTACATCGAGCTATTAAAGAGGCGATATTGAAAAAGTACAGCAAGAAT
AGCACACTTTGTAAATTCAA

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MSKRILSGIQVTGKQHLGNYLGSIQKWVQMQSKFQSIFFLANLHSITTSQESLKLSESIFSSACMLLACGINPKQSIIFL
QSDVKEHSELAWILNCVTPLGQLKRMTQFKDKTIKCSSNNINLGLLAYPVLMAADVLLYQADLVPVGADQKQHLELVRDI
VKIIHHKFNDDTIFKLPELFIDHTAGKIMSLKDGRKKMSKSDISDFSRINLTDSQDVIFRKLQKAKTDCYTQITYDPTSR
PEISNLINIFAALSNKTTNDIVKEYEYAELTKFKKDLAMLIIDCLNPILKEYNNYMNNLDYVNQVLITGANQAKIIAEKT
ITKVKQKFGLQILST

Sequences:

>Translated_335_residues
MSKRILSGIQVTGKQHLGNYLGSIQKWVQMQSKFQSIFFLANLHSITTSQESLKLSESIFSSACMLLACGINPKQSIIFL
QSDVKEHSELAWILNCVTPLGQLKRMTQFKDKTIKCSSNNINLGLLAYPVLMAADVLLYQADLVPVGADQKQHLELVRDI
VKIIHHKFNDDTIFKLPELFIDHTAGKIMSLKDGRKKMSKSDISDFSRINLTDSQDVIFRKLQKAKTDCYTQITYDPTSR
PEISNLINIFAALSNKTTNDIVKEYEYAELTKFKKDLAMLIIDCLNPILKEYNNYMNNLDYVNQVLITGANQAKIIAEKT
ITKVKQKFGLQILST
>Mature_334_residues
SKRILSGIQVTGKQHLGNYLGSIQKWVQMQSKFQSIFFLANLHSITTSQESLKLSESIFSSACMLLACGINPKQSIIFLQ
SDVKEHSELAWILNCVTPLGQLKRMTQFKDKTIKCSSNNINLGLLAYPVLMAADVLLYQADLVPVGADQKQHLELVRDIV
KIIHHKFNDDTIFKLPELFIDHTAGKIMSLKDGRKKMSKSDISDFSRINLTDSQDVIFRKLQKAKTDCYTQITYDPTSRP
EISNLINIFAALSNKTTNDIVKEYEYAELTKFKKDLAMLIIDCLNPILKEYNNYMNNLDYVNQVLITGANQAKIIAEKTI
TKVKQKFGLQILST

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=329, Percent_Identity=39.8176291793313, Blast_Score=257, Evalue=1e-68,
Organism=Homo sapiens, GI41352700, Length=177, Percent_Identity=48.5875706214689, Blast_Score=178, Evalue=7e-45,
Organism=Escherichia coli, GI1789786, Length=328, Percent_Identity=39.0243902439024, Blast_Score=258, Evalue=5e-70,
Organism=Caenorhabditis elegans, GI71982800, Length=330, Percent_Identity=32.7272727272727, Blast_Score=201, Evalue=4e-52,
Organism=Caenorhabditis elegans, GI71982793, Length=330, Percent_Identity=32.7272727272727, Blast_Score=199, Evalue=1e-51,
Organism=Saccharomyces cerevisiae, GI6320474, Length=348, Percent_Identity=36.2068965517241, Blast_Score=201, Evalue=2e-52,
Organism=Drosophila melanogaster, GI24666151, Length=329, Percent_Identity=39.209726443769, Blast_Score=253, Evalue=1e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 37980; Mature: 37849

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKRILSGIQVTGKQHLGNYLGSIQKWVQMQSKFQSIFFLANLHSITTSQESLKLSESIF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
SSACMLLACGINPKQSIIFLQSDVKEHSELAWILNCVTPLGQLKRMTQFKDKTIKCSSNN
HHHHHHHHCCCCCCHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCC
INLGLLAYPVLMAADVLLYQADLVPVGADQKQHLELVRDIVKIIHHKFNDDTIFKLPELF
CCCHHHHHHHHHHHHHHHHHHCCEECCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
IDHTAGKIMSLKDGRKKMSKSDISDFSRINLTDSQDVIFRKLQKAKTDCYTQITYDPTSR
HHHCCCHHEECHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHEEEEEECCCCC
PEISNLINIFAALSNKTTNDIVKEYEYAELTKFKKDLAMLIIDCLNPILKEYNNYMNNLD
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YVNQVLITGANQAKIIAEKTITKVKQKFGLQILST
HHHHHHHCCCCCHHHHHHHHHHHHHHHHCCEECCC
>Mature Secondary Structure 
SKRILSGIQVTGKQHLGNYLGSIQKWVQMQSKFQSIFFLANLHSITTSQESLKLSESIF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
SSACMLLACGINPKQSIIFLQSDVKEHSELAWILNCVTPLGQLKRMTQFKDKTIKCSSNN
HHHHHHHHCCCCCCHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCC
INLGLLAYPVLMAADVLLYQADLVPVGADQKQHLELVRDIVKIIHHKFNDDTIFKLPELF
CCCHHHHHHHHHHHHHHHHHHCCEECCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
IDHTAGKIMSLKDGRKKMSKSDISDFSRINLTDSQDVIFRKLQKAKTDCYTQITYDPTSR
HHHCCCHHEECHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHEEEEEECCCCC
PEISNLINIFAALSNKTTNDIVKEYEYAELTKFKKDLAMLIIDCLNPILKEYNNYMNNLD
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YVNQVLITGANQAKIIAEKTITKVKQKFGLQILST
HHHHHHHCCCCCHHHHHHHHHHHHHHHHCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]