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The map label for this gene is dtpD [H]

Identifier: 148284382

GI number: 148284382

Start: 641055

End: 642533

Strand: Direct

Name: dtpD [H]

Synonym: OTBS_0662

Alternate gene names: 148284382

Gene position: 641055-642533 (Clockwise)

Preceding gene: 148284380

Following gene: 148284385

Centisome position: 30.14

GC content: 31.24

Gene sequence:

>1479_bases
ATGAATAAATCAATCAGTGTATTAAATACAACAACCACAGTTAGAAAATTTCCGCAATTTTTATTGTTATTATTCTTTGT
TGAGATGTGGGAACGCTTTAGTTATTATGGAATGAGGTCACTTTTAGTGCTTTTTCTAACTTCTCAGTTAGGCTTTACTG
ATATAAAAGCTTATACTACATACTCTTTATTTGCTGTAGTATGTTATGCTGGACCAGTGATCGGAGGCATTTTAGCGGAT
AAATTAATGGGATTCCGCAGCATGGTACTAATAGGAGGAATTGTTATGGTAGCTGGACATATGAGCATGCTGCTAGTAGG
ATTTAATTCAGACCTAATATATTTTAGTCTATCTTTAATAGCTGTAGGCACTGGAATGTTTAAAGGTAATATCTTGAACT
TACTTGGAGCTTGTTATAGGACAGATGATTCTGAACGTAGCAGAGGGTTTACTTTGTTTTATGTAGGAATTAATTTAGGT
GCAACATTAGCAGCTATTTCTTGTGGGTATATAGCTCATTTATATGGTTGGCACTATGGATTTGGTCTAGCAGGCATTGG
CATGACTATTGGTCTTATTACTTTTATAATATTTCAAAACATATTAGGAGATAAAGGTCTTTCTGCCTATCCTATGCTTA
TGAATAAAAGAATGCTAGGAATAAATATTTTTGGAATAGTATTAGCTGGTTGCTTCTTGCTGGCATTAATGGTATCTAAA
ATGCTTATATTTAGCGAACTCTTTACTTCTGCGCTTACATTTAGTGGAATAATAGTTCTAGGAGTATTTATTAGTATAAT
ATTCAAAACATCAGTTGAGCAAAGACCAAAGTTAGTAGTATTAGCAATTCTTATGATATTCCAGATGTTATTTTTTGCAC
TAGAAATGCAACTTGGTTCTTTAATTAACTTGTTTACTGAAAGAAATGTTGCTAACAATATCTTAGGTATAACAATTCCA
GCTTCAGTATCTCAAGCAATCAATCCTATATCAATTACAATACTTGGATCTCTCTTTGGAATGTTTTCAAAGTTCAGAAA
AAAAGATGCTGCTGCTATCTTTGCTTTTGGTCTTTTTACAATTTCTATATGTTTTTTTATTTTATATACAGGATGTTTGA
ATGCTAATGATGGAAAAGTAAACTATTTATATCTAATAGCTGCTATTTCTATTATGGGACTAGGAGAGCTTTGTGTTGCA
CCATTAGTACAAGAACAAGCAACTTTATTATCTCCTAAAAATGCAAAAGGAGCATTAATGGGTATGATGATATTATCATT
AGCATTTTCTAACCTAATTGGTATGGTGGTATCAAACTGTATGTTAGTACCTTCTGTAAATGGCGAAGTAAATCGTTTTG
AATCTTTAGCAATATATCAAGAGGGATTTTTAAATGTAACAATATCTGCTGCAATATTAAGTATTATATTTTTACTTTTC
TTTAAAATGATACATAAAGTTATTGCTATGCAAGAATAA

Upstream 100 bases:

>100_bases
TTTTGATTGTTAATCTTTTTTTTACTGAAGCTATAAGTATAGAGTCATAATTTACTTAAAATTACTTTAAAATTAACTAA
TTAGTGTAATGGAATAGTTT

Downstream 100 bases:

>100_bases
TTACAATCCAAATAGGATTTTAACTATTTAAAAACACAAGAGTTCGATATAATTGAGAACAACAGAAAGTAGGAAAAATG
TGATGTAATCTTTATATCGA

Product: putative amino acid/peptide transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 492; Mature: 492

Protein sequence:

>492_residues
MNKSISVLNTTTTVRKFPQFLLLLFFVEMWERFSYYGMRSLLVLFLTSQLGFTDIKAYTTYSLFAVVCYAGPVIGGILAD
KLMGFRSMVLIGGIVMVAGHMSMLLVGFNSDLIYFSLSLIAVGTGMFKGNILNLLGACYRTDDSERSRGFTLFYVGINLG
ATLAAISCGYIAHLYGWHYGFGLAGIGMTIGLITFIIFQNILGDKGLSAYPMLMNKRMLGINIFGIVLAGCFLLALMVSK
MLIFSELFTSALTFSGIIVLGVFISIIFKTSVEQRPKLVVLAILMIFQMLFFALEMQLGSLINLFTERNVANNILGITIP
ASVSQAINPISITILGSLFGMFSKFRKKDAAAIFAFGLFTISICFFILYTGCLNANDGKVNYLYLIAAISIMGLGELCVA
PLVQEQATLLSPKNAKGALMGMMILSLAFSNLIGMVVSNCMLVPSVNGEVNRFESLAIYQEGFLNVTISAAILSIIFLLF
FKMIHKVIAMQE

Sequences:

>Translated_492_residues
MNKSISVLNTTTTVRKFPQFLLLLFFVEMWERFSYYGMRSLLVLFLTSQLGFTDIKAYTTYSLFAVVCYAGPVIGGILAD
KLMGFRSMVLIGGIVMVAGHMSMLLVGFNSDLIYFSLSLIAVGTGMFKGNILNLLGACYRTDDSERSRGFTLFYVGINLG
ATLAAISCGYIAHLYGWHYGFGLAGIGMTIGLITFIIFQNILGDKGLSAYPMLMNKRMLGINIFGIVLAGCFLLALMVSK
MLIFSELFTSALTFSGIIVLGVFISIIFKTSVEQRPKLVVLAILMIFQMLFFALEMQLGSLINLFTERNVANNILGITIP
ASVSQAINPISITILGSLFGMFSKFRKKDAAAIFAFGLFTISICFFILYTGCLNANDGKVNYLYLIAAISIMGLGELCVA
PLVQEQATLLSPKNAKGALMGMMILSLAFSNLIGMVVSNCMLVPSVNGEVNRFESLAIYQEGFLNVTISAAILSIIFLLF
FKMIHKVIAMQE
>Mature_492_residues
MNKSISVLNTTTTVRKFPQFLLLLFFVEMWERFSYYGMRSLLVLFLTSQLGFTDIKAYTTYSLFAVVCYAGPVIGGILAD
KLMGFRSMVLIGGIVMVAGHMSMLLVGFNSDLIYFSLSLIAVGTGMFKGNILNLLGACYRTDDSERSRGFTLFYVGINLG
ATLAAISCGYIAHLYGWHYGFGLAGIGMTIGLITFIIFQNILGDKGLSAYPMLMNKRMLGINIFGIVLAGCFLLALMVSK
MLIFSELFTSALTFSGIIVLGVFISIIFKTSVEQRPKLVVLAILMIFQMLFFALEMQLGSLINLFTERNVANNILGITIP
ASVSQAINPISITILGSLFGMFSKFRKKDAAAIFAFGLFTISICFFILYTGCLNANDGKVNYLYLIAAISIMGLGELCVA
PLVQEQATLLSPKNAKGALMGMMILSLAFSNLIGMVVSNCMLVPSVNGEVNRFESLAIYQEGFLNVTISAAILSIIFLLF
FKMIHKVIAMQE

Specific function: Probable proton-dependent permease that transports dipeptides [H]

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family. DtpD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4827008, Length=207, Percent_Identity=28.5024154589372, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI226371746, Length=186, Percent_Identity=29.5698924731183, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI226371748, Length=179, Percent_Identity=29.608938547486, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1786927, Length=467, Percent_Identity=32.762312633833, Blast_Score=222, Evalue=5e-59,
Organism=Escherichia coli, GI1787922, Length=478, Percent_Identity=30.9623430962343, Blast_Score=222, Evalue=5e-59,
Organism=Escherichia coli, GI1790572, Length=479, Percent_Identity=32.1503131524008, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI1789911, Length=496, Percent_Identity=28.8306451612903, Blast_Score=191, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI71987453, Length=161, Percent_Identity=32.9192546583851, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17569141, Length=161, Percent_Identity=31.6770186335404, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24639585, Length=332, Percent_Identity=26.8072289156627, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24639583, Length=339, Percent_Identity=26.5486725663717, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24639581, Length=332, Percent_Identity=26.8072289156627, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI28571102, Length=216, Percent_Identity=25.9259259259259, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI28571100, Length=216, Percent_Identity=25.9259259259259, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI28571098, Length=216, Percent_Identity=25.9259259259259, Blast_Score=66, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 53838; Mature: 53838

Theoretical pI: Translated: 9.11; Mature: 9.11

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKSISVLNTTTTVRKFPQFLLLLFFVEMWERFSYYGMRSLLVLFLTSQLGFTDIKAYTT
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
YSLFAVVCYAGPVIGGILADKLMGFRSMVLIGGIVMVAGHMSMLLVGFNSDLIYFSLSLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHH
AVGTGMFKGNILNLLGACYRTDDSERSRGFTLFYVGINLGATLAAISCGYIAHLYGWHYG
HHHCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHH
FGLAGIGMTIGLITFIIFQNILGDKGLSAYPMLMNKRMLGINIFGIVLAGCFLLALMVSK
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
MLIFSELFTSALTFSGIIVLGVFISIIFKTSVEQRPKLVVLAILMIFQMLFFALEMQLGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
LINLFTERNVANNILGITIPASVSQAINPISITILGSLFGMFSKFRKKDAAAIFAFGLFT
HHHHHHHCCHHCCEEEEEECHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISICFFILYTGCLNANDGKVNYLYLIAAISIMGLGELCVAPLVQEQATLLSPKNAKGALM
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHH
GMMILSLAFSNLIGMVVSNCMLVPSVNGEVNRFESLAIYQEGFLNVTISAAILSIIFLLF
HHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
FKMIHKVIAMQE
HHHHHHHHHCCC
>Mature Secondary Structure
MNKSISVLNTTTTVRKFPQFLLLLFFVEMWERFSYYGMRSLLVLFLTSQLGFTDIKAYTT
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
YSLFAVVCYAGPVIGGILADKLMGFRSMVLIGGIVMVAGHMSMLLVGFNSDLIYFSLSLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHH
AVGTGMFKGNILNLLGACYRTDDSERSRGFTLFYVGINLGATLAAISCGYIAHLYGWHYG
HHHCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHH
FGLAGIGMTIGLITFIIFQNILGDKGLSAYPMLMNKRMLGINIFGIVLAGCFLLALMVSK
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
MLIFSELFTSALTFSGIIVLGVFISIIFKTSVEQRPKLVVLAILMIFQMLFFALEMQLGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
LINLFTERNVANNILGITIPASVSQAINPISITILGSLFGMFSKFRKKDAAAIFAFGLFT
HHHHHHHCCHHCCEEEEEECHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISICFFILYTGCLNANDGKVNYLYLIAAISIMGLGELCVAPLVQEQATLLSPKNAKGALM
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHH
GMMILSLAFSNLIGMVVSNCMLVPSVNGEVNRFESLAIYQEGFLNVTISAAILSIIFLLF
HHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
FKMIHKVIAMQE
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]