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The map label for this gene is qor [H]

Identifier: 148284297

GI number: 148284297

Start: 477577

End: 478740

Strand: Direct

Name: qor [H]

Synonym: OTBS_0501

Alternate gene names: 148284297

Gene position: 477577-478740 (Clockwise)

Preceding gene: 148284292

Following gene: 148284300

Centisome position: 22.45

GC content: 30.07

Gene sequence:

>1164_bases
ATGCATAAACAAAAATTATATCGTATAACTTATGGTAATAGTAATCCAAGGTTTGAATTAGTTGAAGCAGATATTCCTAC
TCCAAAAGATGACGAAATACTAATTAAACACACTGCTATCGGAATTAATTTTCAAGATTATGAACATTATAAAAAAACTC
TAGTTTCTATATCTAAACCAGTTATAACAAATAATGAGAAGTCGTTTGGAGTATACAGCAACATCAAGCAAGCAATTAAG
TCTTTTTTACATAATCCTTCTAATCAAGCTACTCAGGCTACTCAGGCTACTCAGGCTACTCAAGTAAGCAGTGATAATAA
TATTGCATCAAATAATACATTTAGTAATATTGTTACAATCACACCTGGCATAGAAGCAGTTGGTATAGTGCATAAAATAG
GAAAATTAGTTAAAGATTTTCAAGTAGGACAACGAGTTGGCTATTGTACCGTTACAGATGGAGCATATAGCCAATATAGA
ACAATAAATTCTAACTATGTTTTTAAAATTCAAGATTCTATATCTGATGAAGCAGCAGCAGCAAATTTAGTTAAAGGAAT
GACTGCTCATTATTTGATGAGAAGAACTTTTTATGTACAGCCAAATATGACTATACTAATTCATGCTGCTAGTAGCGCTG
TTGGCCAAACAATGCTTAGACTTGTAAAAGAATATAAAGCTACAGCAATAGCTACTATAGGCAATGATGACCAAGAAAAG
AAATCTATTCTTCAAAATCTTGAATGTGAATATATATTAAATTATAATAATCCAGATTGGGTAAATCAAGTAAAAGAAAT
TACTAATAATAAAGGAGTTAATGTAGTTTATGATTGTTTAGGACGGCAAACTGTTTTAGAATCTATTGACTGCTTAATGC
CGTTTGGATTAATGGTTCTTTTGGGTCAAATTACCGGTAGCGTTAATACAATTGATCCGCAATTACTAACTCAAAAATCT
TTATTTTTTACAATGCCACAATTACAGTATTATAAACAAGATAATATAGAGCTTTTGCTTAGTGCTCTGGAAGTATTTGC
TCTAATAGAAAAAGGAGTATTACCTAAAAAAGCAAATCAAATTTACAAATTTGATAACGTAGTACAAGCAATGCATGATA
TAGAAAATCATAGAAATTTAGGCACTAAAATTGTACTGTTATAA

Upstream 100 bases:

>100_bases
AAATGGTAATTATCGAAAGCAATAATTTTAAGCACACTATTCTCTAAAATTAAAAATATTTAATTACAAAAAGCAAATTA
ATAAATTAAATTTTAATATT

Downstream 100 bases:

>100_bases
AATAAATTATTAATCGTTAAAATTATTTTATTAATTGCATATTTTATTCGCTAATACTTTTTTGGTAATTATTATATAAT
CCTATCTTCTAATATAGCTA

Product: NADP-dependent quinone oxidoreductase

Products: NA

Alternate protein names: NADPH:quinone reductase 1; Zeta-crystallin homolog protein [H]

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MHKQKLYRITYGNSNPRFELVEADIPTPKDDEILIKHTAIGINFQDYEHYKKTLVSISKPVITNNEKSFGVYSNIKQAIK
SFLHNPSNQATQATQATQATQVSSDNNIASNNTFSNIVTITPGIEAVGIVHKIGKLVKDFQVGQRVGYCTVTDGAYSQYR
TINSNYVFKIQDSISDEAAAANLVKGMTAHYLMRRTFYVQPNMTILIHAASSAVGQTMLRLVKEYKATAIATIGNDDQEK
KSILQNLECEYILNYNNPDWVNQVKEITNNKGVNVVYDCLGRQTVLESIDCLMPFGLMVLLGQITGSVNTIDPQLLTQKS
LFFTMPQLQYYKQDNIELLLSALEVFALIEKGVLPKKANQIYKFDNVVQAMHDIENHRNLGTKIVLL

Sequences:

>Translated_387_residues
MHKQKLYRITYGNSNPRFELVEADIPTPKDDEILIKHTAIGINFQDYEHYKKTLVSISKPVITNNEKSFGVYSNIKQAIK
SFLHNPSNQATQATQATQATQVSSDNNIASNNTFSNIVTITPGIEAVGIVHKIGKLVKDFQVGQRVGYCTVTDGAYSQYR
TINSNYVFKIQDSISDEAAAANLVKGMTAHYLMRRTFYVQPNMTILIHAASSAVGQTMLRLVKEYKATAIATIGNDDQEK
KSILQNLECEYILNYNNPDWVNQVKEITNNKGVNVVYDCLGRQTVLESIDCLMPFGLMVLLGQITGSVNTIDPQLLTQKS
LFFTMPQLQYYKQDNIELLLSALEVFALIEKGVLPKKANQIYKFDNVVQAMHDIENHRNLGTKIVLL
>Mature_387_residues
MHKQKLYRITYGNSNPRFELVEADIPTPKDDEILIKHTAIGINFQDYEHYKKTLVSISKPVITNNEKSFGVYSNIKQAIK
SFLHNPSNQATQATQATQATQVSSDNNIASNNTFSNIVTITPGIEAVGIVHKIGKLVKDFQVGQRVGYCTVTDGAYSQYR
TINSNYVFKIQDSISDEAAAANLVKGMTAHYLMRRTFYVQPNMTILIHAASSAVGQTMLRLVKEYKATAIATIGNDDQEK
KSILQNLECEYILNYNNPDWVNQVKEITNNKGVNVVYDCLGRQTVLESIDCLMPFGLMVLLGQITGSVNTIDPQLLTQKS
LFFTMPQLQYYKQDNIELLLSALEVFALIEKGVLPKKANQIYKFDNVVQAMHDIENHRNLGTKIVLL

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI18379349, Length=289, Percent_Identity=24.9134948096886, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI24308257, Length=289, Percent_Identity=24.9134948096886, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI194239674, Length=279, Percent_Identity=21.8637992831541, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI13236495, Length=279, Percent_Identity=21.8637992831541, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI22538446, Length=194, Percent_Identity=27.8350515463918, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI22538444, Length=194, Percent_Identity=27.8350515463918, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI28557745, Length=185, Percent_Identity=27.5675675675676, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1790485, Length=267, Percent_Identity=36.7041198501873, Blast_Score=160, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI17507255, Length=265, Percent_Identity=20.377358490566, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319520, Length=268, Percent_Identity=31.3432835820896, Blast_Score=108, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 43455; Mature: 43455

Theoretical pI: Translated: 8.27; Mature: 8.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKQKLYRITYGNSNPRFELVEADIPTPKDDEILIKHTAIGINFQDYEHYKKTLVSISKP
CCCCEEEEEEECCCCCCEEEEECCCCCCCCCCEEEEEEEEECCHHHHHHHHHHHHHHCCC
VITNNEKSFGVYSNIKQAIKSFLHNPSNQATQATQATQATQVSSDNNIASNNTFSNIVTI
EEECCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEE
TPGIEAVGIVHKIGKLVKDFQVGQRVGYCTVTDGAYSQYRTINSNYVFKIQDSISDEAAA
CCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHEEECCCEEEEECCCCCHHHHH
ANLVKGMTAHYLMRRTFYVQPNMTILIHAASSAVGQTMLRLVKEYKATAIATIGNDDQEK
HHHHHHHHHHHHHHHEEEECCCCEEEEEECHHHHHHHHHHHHHHHHHHEEEECCCCCHHH
KSILQNLECEYILNYNNPDWVNQVKEITNNKGVNVVYDCLGRQTVLESIDCLMPFGLMVL
HHHHHCCCEEEEEECCCCHHHHHHHHHHCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHH
LGQITGSVNTIDPQLLTQKSLFFTMPQLQYYKQDNIELLLSALEVFALIEKGVLPKKANQ
HHHHCCCCCCCCHHHHHHHHHHEECCHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHH
IYKFDNVVQAMHDIENHRNLGTKIVLL
HHHHHHHHHHHHHHHHHHCCCCEEEEC
>Mature Secondary Structure
MHKQKLYRITYGNSNPRFELVEADIPTPKDDEILIKHTAIGINFQDYEHYKKTLVSISKP
CCCCEEEEEEECCCCCCEEEEECCCCCCCCCCEEEEEEEEECCHHHHHHHHHHHHHHCCC
VITNNEKSFGVYSNIKQAIKSFLHNPSNQATQATQATQATQVSSDNNIASNNTFSNIVTI
EEECCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEE
TPGIEAVGIVHKIGKLVKDFQVGQRVGYCTVTDGAYSQYRTINSNYVFKIQDSISDEAAA
CCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHEEECCCEEEEECCCCCHHHHH
ANLVKGMTAHYLMRRTFYVQPNMTILIHAASSAVGQTMLRLVKEYKATAIATIGNDDQEK
HHHHHHHHHHHHHHHEEEECCCCEEEEEECHHHHHHHHHHHHHHHHHHEEEECCCCCHHH
KSILQNLECEYILNYNNPDWVNQVKEITNNKGVNVVYDCLGRQTVLESIDCLMPFGLMVL
HHHHHCCCEEEEEECCCCHHHHHHHHHHCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHH
LGQITGSVNTIDPQLLTQKSLFFTMPQLQYYKQDNIELLLSALEVFALIEKGVLPKKANQ
HHHHCCCCCCCCHHHHHHHHHHEECCHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHHH
IYKFDNVVQAMHDIENHRNLGTKIVLL
HHHHHHHHHHHHHHHHHHCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 7602590 [H]