Click here to switch to the map view.

The map label for this gene is fabZ [H]

Identifier: 148284238

GI number: 148284238

Start: 384314

End: 384817

Strand: Direct

Name: fabZ [H]

Synonym: OTBS_0404

Alternate gene names: 148284238

Gene position: 384314-384817 (Clockwise)

Preceding gene: 148284236

Following gene: 148284239

Centisome position: 18.07

GC content: 29.76

Gene sequence:

>504_bases
ATGTCTCAACAAAAACAACTATCAGAAAATAACTGTGTATTGAGCACACAAGACATCATTAGGATTATACCACATAGATA
TCCTTTCTTAATGATAGATAAAGTTATAAAACTAGAACCTGGTCAAAAAATCATAGGAATTAAGAATGTTACAGCTAATG
AGCCGCAGTTCACAGGTCATTTTCCTAACAATCCAGTTATGCCAGGAGTTCTAACCATTGAATCAATGGCTCAGTTATCT
GCTATTTTAGTAGCAAAAACTATTATGTTCGATACTAACAGCAAAATTTTCTACTTAATAAATATTGAAAACGTAAAATT
CAGGAAAATAATTACTAGTGGAGATACCATGGTTATTACATCTAAAATTTCTCAAGCTTATAATAAGAGTATATGGAAAT
TTAATGCAGAAGTTAAAATTGAAGGTACAAATAACCTAGCTGCTGAAGGAACATTTACCGGAGGTATAAAAGATTTATTA
AAACCTAATTCTAAAATAAATTAG

Upstream 100 bases:

>100_bases
CATATTATTATTATAAAGACTCAAATTATTAAAGCCATTACTATTCTAGTAATATAGTTATTAAACAATCTTAAAAAAAT
AATGTAGCAAAGATAAGATA

Downstream 100 bases:

>100_bases
CTTATGATTCAAATAATTTCGGGAAAATTTAAAGGACAAAAAATTCCAGTTATTAAAAATAATAATTATCGCCCATCCAC
TGCTAAATTAAAAGAATCTA

Product: (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase [H]

Number of amino acids: Translated: 167; Mature: 166

Protein sequence:

>167_residues
MSQQKQLSENNCVLSTQDIIRIIPHRYPFLMIDKVIKLEPGQKIIGIKNVTANEPQFTGHFPNNPVMPGVLTIESMAQLS
AILVAKTIMFDTNSKIFYLINIENVKFRKIITSGDTMVITSKISQAYNKSIWKFNAEVKIEGTNNLAAEGTFTGGIKDLL
KPNSKIN

Sequences:

>Translated_167_residues
MSQQKQLSENNCVLSTQDIIRIIPHRYPFLMIDKVIKLEPGQKIIGIKNVTANEPQFTGHFPNNPVMPGVLTIESMAQLS
AILVAKTIMFDTNSKIFYLINIENVKFRKIITSGDTMVITSKISQAYNKSIWKFNAEVKIEGTNNLAAEGTFTGGIKDLL
KPNSKIN
>Mature_166_residues
SQQKQLSENNCVLSTQDIIRIIPHRYPFLMIDKVIKLEPGQKIIGIKNVTANEPQFTGHFPNNPVMPGVLTIESMAQLSA
ILVAKTIMFDTNSKIFYLINIENVKFRKIITSGDTMVITSKISQAYNKSIWKFNAEVKIEGTNNLAAEGTFTGGIKDLLK
PNSKIN

Specific function: Involved in saturated fatty acids biosynthesis [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786377, Length=136, Percent_Identity=32.3529411764706, Blast_Score=110, Evalue=6e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013114
- InterPro:   IPR010084 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: 4.2.1.-

Molecular weight: Translated: 18670; Mature: 18539

Theoretical pI: Translated: 10.08; Mature: 10.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQQKQLSENNCVLSTQDIIRIIPHRYPFLMIDKVIKLEPGQKIIGIKNVTANEPQFTGH
CCCCCCCCCCCCEEEHHHHHHHCCCCCCCEEECCEEEECCCCEEEEEECCCCCCCEEECC
FPNNPVMPGVLTIESMAQLSAILVAKTIMFDTNSKIFYLINIENVKFRKIITSGDTMVIT
CCCCCCCCCEEEHHHHHHHHHHHHHHEEEEECCCCEEEEEEECCEEEEEEEECCCEEEEE
SKISQAYNKSIWKFNAEVKIEGTNNLAAEGTFTGGIKDLLKPNSKIN
HHHHHHHCCCEEEECCEEEEECCCCEEECCEECCCHHHHHCCCCCCC
>Mature Secondary Structure 
SQQKQLSENNCVLSTQDIIRIIPHRYPFLMIDKVIKLEPGQKIIGIKNVTANEPQFTGH
CCCCCCCCCCCEEEHHHHHHHCCCCCCCEEECCEEEECCCCEEEEEECCCCCCCEEECC
FPNNPVMPGVLTIESMAQLSAILVAKTIMFDTNSKIFYLINIENVKFRKIITSGDTMVIT
CCCCCCCCCEEEHHHHHHHHHHHHHHEEEEECCCCEEEEEEECCEEEEEEEECCCEEEEE
SKISQAYNKSIWKFNAEVKIEGTNNLAAEGTFTGGIKDLLKPNSKIN
HHHHHHHCCCEEEECCEEEEECCCCEEECCEECCCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA