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The map label for this gene is hisC [H]

Identifier: 148269110

GI number: 148269110

Start: 2872524

End: 2873537

Strand: Reverse

Name: hisC [H]

Synonym: SaurJH9_2701

Alternate gene names: 148269110

Gene position: 2873537-2872524 (Counterclockwise)

Preceding gene: 148269111

Following gene: 148269109

Centisome position: 98.86

GC content: 34.71

Gene sequence:

>1014_bases
ATGATTTATATTGATAAAAATGAAAGTCCAGTTACGCCGTTGGATGAAAAAACAATGACGTCTATTATTAGTGCAACGCC
ATATAATTTATATCCTGATGCAGCATATGAACAATTCAAGGAAGCTTATGCTAAGTTTTACGGATTATCGCCTGAACAAA
TTATTGCAGGAAATGGATCTGATGAATTGATTCAAAAGTTAATGCTGATCATGCCAGAAGGTCCGGCATTAACGCTAAAT
CCTGATTTTTTTATGTATCAAGCATATGCGGCACAAGTAAATCGTGAAATTGCATTTGTAGATGCAGGATCAGATTTAAC
GTTTGATTTGGAAACCATTTTAACGAAAATCGATGAAGTACAACCATCATTTTTTATTATGAGTAATCCACATAACCCTT
CAGGCAAGCAATTTGATACGGCATTTTTAACAGCTATTGCAGATAAGATGAAAGCATTAAACGGATACTTTGTCATTGAT
GAAGCATATTTAGATTATGGTACGGCATATGACGTGGAACTGGCACCACACATCTTAAGAATGCGTACATTATCAAAGGC
GTTTGGAATTGCCGGCTTAAGATTAGGTGTCTTAATTAGTACTGCTGGAACGATAAAGCATATTCAAAAAATAGAACATC
CATATCCATTAAATGTATTTACGCTAAATATTGCGACTTATATTTTTAGACATAGAGAAGAGACAAGAGTATTTTTAACG
ATGCAACGACAGTTAGCTGAGCAGTTAAAACAAATATTTGATACACATGTTGCAGATAAAATGTCAGTATTCCCATCAAA
TGCCAATTTTGTACTTACTAAAGGTTCAGCAGCGCACCAATTAGGACAATACGTATATGAACAAGGATTTAAACCTCGCT
TTTATGATGAGCCGGTGATGAAGGGCTATGTAAGATACTCAATTGCAACAGCATCGCAGTTAAAGCAATTAGAAGAAATT
GTTAAAGAATGGAGCGCAAAATATGATTTATCAAAAACAACGAAACACAGCTGA

Upstream 100 bases:

>100_bases
ACAAATTGCTGATTCAGCACAACATATTGCTCATGTTGAAGCATTATACAATCACCAGCAGTCTATTTTAATACGTCAGT
CTTAGGGGAGTGTAATTGAA

Downstream 100 bases:

>100_bases
AACACAACTAAATATTTCAATATCAGATGACCAGTCACCATCGCATATTAATACAGGTGTGGGCTTTTTAAATCATATGT
TAACATTGTTTACATTTCAT

Product: aminotransferase, class I and II

Products: NA

Alternate protein names: Imidazole acetol-phosphate transaminase [H]

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MIYIDKNESPVTPLDEKTMTSIISATPYNLYPDAAYEQFKEAYAKFYGLSPEQIIAGNGSDELIQKLMLIMPEGPALTLN
PDFFMYQAYAAQVNREIAFVDAGSDLTFDLETILTKIDEVQPSFFIMSNPHNPSGKQFDTAFLTAIADKMKALNGYFVID
EAYLDYGTAYDVELAPHILRMRTLSKAFGIAGLRLGVLISTAGTIKHIQKIEHPYPLNVFTLNIATYIFRHREETRVFLT
MQRQLAEQLKQIFDTHVADKMSVFPSNANFVLTKGSAAHQLGQYVYEQGFKPRFYDEPVMKGYVRYSIATASQLKQLEEI
VKEWSAKYDLSKTTKHS

Sequences:

>Translated_337_residues
MIYIDKNESPVTPLDEKTMTSIISATPYNLYPDAAYEQFKEAYAKFYGLSPEQIIAGNGSDELIQKLMLIMPEGPALTLN
PDFFMYQAYAAQVNREIAFVDAGSDLTFDLETILTKIDEVQPSFFIMSNPHNPSGKQFDTAFLTAIADKMKALNGYFVID
EAYLDYGTAYDVELAPHILRMRTLSKAFGIAGLRLGVLISTAGTIKHIQKIEHPYPLNVFTLNIATYIFRHREETRVFLT
MQRQLAEQLKQIFDTHVADKMSVFPSNANFVLTKGSAAHQLGQYVYEQGFKPRFYDEPVMKGYVRYSIATASQLKQLEEI
VKEWSAKYDLSKTTKHS
>Mature_337_residues
MIYIDKNESPVTPLDEKTMTSIISATPYNLYPDAAYEQFKEAYAKFYGLSPEQIIAGNGSDELIQKLMLIMPEGPALTLN
PDFFMYQAYAAQVNREIAFVDAGSDLTFDLETILTKIDEVQPSFFIMSNPHNPSGKQFDTAFLTAIADKMKALNGYFVID
EAYLDYGTAYDVELAPHILRMRTLSKAFGIAGLRLGVLISTAGTIKHIQKIEHPYPLNVFTLNIATYIFRHREETRVFLT
MQRQLAEQLKQIFDTHVADKMSVFPSNANFVLTKGSAAHQLGQYVYEQGFKPRFYDEPVMKGYVRYSIATASQLKQLEEI
VKEWSAKYDLSKTTKHS

Specific function: Histidine biosynthesis; seventh step. [C]

COG id: COG0079

COG function: function code E; Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788332, Length=330, Percent_Identity=26.0606060606061, Blast_Score=109, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6322075, Length=358, Percent_Identity=27.6536312849162, Blast_Score=86, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR005861
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.9 [H]

Molecular weight: Translated: 38221; Mature: 38221

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: PS00599 AA_TRANSFER_CLASS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYIDKNESPVTPLDEKTMTSIISATPYNLYPDAAYEQFKEAYAKFYGLSPEQIIAGNGS
CEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHEEECCCH
DELIQKLMLIMPEGPALTLNPDFFMYQAYAAQVNREIAFVDAGSDLTFDLETILTKIDEV
HHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHCCEEEEEECCCCCEEEHHHHHHHHHHC
QPSFFIMSNPHNPSGKQFDTAFLTAIADKMKALNGYFVIDEAYLDYGTAYDVELAPHILR
CCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEHHHHCCCCEEECHHHHHHHH
MRTLSKAFGIAGLRLGVLISTAGTIKHIQKIEHPYPLNVFTLNIATYIFRHREETRVFLT
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCEEEEHHHHHHHHHCCCCHHHHHH
MQRQLAEQLKQIFDTHVADKMSVFPSNANFVLTKGSAAHQLGQYVYEQGFKPRFYDEPVM
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHCCCCCCCCCCHHH
KGYVRYSIATASQLKQLEEIVKEWSAKYDLSKTTKHS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MIYIDKNESPVTPLDEKTMTSIISATPYNLYPDAAYEQFKEAYAKFYGLSPEQIIAGNGS
CEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHEEECCCH
DELIQKLMLIMPEGPALTLNPDFFMYQAYAAQVNREIAFVDAGSDLTFDLETILTKIDEV
HHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHCCEEEEEECCCCCEEEHHHHHHHHHHC
QPSFFIMSNPHNPSGKQFDTAFLTAIADKMKALNGYFVIDEAYLDYGTAYDVELAPHILR
CCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEHHHHCCCCEEECHHHHHHHH
MRTLSKAFGIAGLRLGVLISTAGTIKHIQKIEHPYPLNVFTLNIATYIFRHREETRVFLT
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCEEEEHHHHHHHHHCCCCHHHHHH
MQRQLAEQLKQIFDTHVADKMSVFPSNANFVLTKGSAAHQLGQYVYEQGFKPRFYDEPVM
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHCCCCCCCCCCHHH
KGYVRYSIATASQLKQLEEIVKEWSAKYDLSKTTKHS
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA