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The map label for this gene is sirC [H]

Identifier: 148269051

GI number: 148269051

Start: 2797242

End: 2797847

Strand: Reverse

Name: sirC [H]

Synonym: SaurJH9_2642

Alternate gene names: 148269051

Gene position: 2797847-2797242 (Counterclockwise)

Preceding gene: 148269052

Following gene: 148269050

Centisome position: 96.26

GC content: 37.29

Gene sequence:

>606_bases
ATGAATATGCCATTAATGATAGATTTAACAAATAAAAATGTCGTCATAGTTGGTGGAGGCGTCGTTGCAAGTCGTCGGGC
ACAAACATTAAATCAATACGTTGAACATATGACGGTCATCAGTCCGACAATCACTGAAAAACTTCAAAATATGGTAGATA
ACGGTGTCGTCATATGGAAAGAAAAAGAATTTGAACCAAGCGATATTGTAGACGCGTATCTAGTTATTGCAGCAACCAAT
GAGCCACGTGTCAATGAAGCGGTAAAACAAGCCTTACCTGAGCATGCCCTTTTTAATAATGTTGGAGATGCATCAAATGG
CAATGTTGTATTTCCAAGTGCACTACACCGCGACAAGCTAACTATCAGTGTATCAACTGATGGTGCGAGTCCTAAGTTGA
CAAAATCAATTATGGCAGAGCTTGAGGCGTTATATCCACCATCATACAGTTCGTATATCGACTTTTTATATACTTGCCGA
CAGAAAATAAAAGTACTTGATATAACATATAACGAAAAGCAACAGTTACTGTCACAAATTGTGTCACAAGAATATTTAAA
TCATGACAAACAAGCTCAATTTTTAGCGTGGTTGGATGTAAGATAA

Upstream 100 bases:

>100_bases
TGAAACAACAACAACGCTATCAACGTGATGTTTATTAGCGATTGGTGTTAAATATTTTAAGGTGTAATGATGTAAAAAGA
TATAAAGGATGTTGCTCAAC

Downstream 100 bases:

>100_bases
TAATAGCGGACCGTCTAACCGTCTAAGGTAAGTCTTCTTATTTTAACTTTAACGCTTAATCATTGAAATTAAGACATGGG
TGGCTTTGTGAATAGTCTAA

Product: precorrin-2 dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MNMPLMIDLTNKNVVIVGGGVVASRRAQTLNQYVEHMTVISPTITEKLQNMVDNGVVIWKEKEFEPSDIVDAYLVIAATN
EPRVNEAVKQALPEHALFNNVGDASNGNVVFPSALHRDKLTISVSTDGASPKLTKSIMAELEALYPPSYSSYIDFLYTCR
QKIKVLDITYNEKQQLLSQIVSQEYLNHDKQAQFLAWLDVR

Sequences:

>Translated_201_residues
MNMPLMIDLTNKNVVIVGGGVVASRRAQTLNQYVEHMTVISPTITEKLQNMVDNGVVIWKEKEFEPSDIVDAYLVIAATN
EPRVNEAVKQALPEHALFNNVGDASNGNVVFPSALHRDKLTISVSTDGASPKLTKSIMAELEALYPPSYSSYIDFLYTCR
QKIKVLDITYNEKQQLLSQIVSQEYLNHDKQAQFLAWLDVR
>Mature_201_residues
MNMPLMIDLTNKNVVIVGGGVVASRRAQTLNQYVEHMTVISPTITEKLQNMVDNGVVIWKEKEFEPSDIVDAYLVIAATN
EPRVNEAVKQALPEHALFNNVGDASNGNVVFPSALHRDKLTISVSTDGASPKLTKSIMAELEALYPPSYSSYIDFLYTCR
QKIKVLDITYNEKQQLLSQIVSQEYLNHDKQAQFLAWLDVR

Specific function: Catalyzes the dehydrogenation of precorrin-2 to form sirohydrochlorin used as precursor in both siroheme biosynthesis and in the anaerobic branch of adenosylcobalamin biosynthesis [H]

COG id: COG1648

COG function: function code H; Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789768, Length=197, Percent_Identity=27.4111675126904, Blast_Score=88, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR006367 [H]

Pfam domain/function: NA

EC number: =1.3.1.76 [H]

Molecular weight: Translated: 22542; Mature: 22542

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNMPLMIDLTNKNVVIVGGGVVASRRAQTLNQYVEHMTVISPTITEKLQNMVDNGVVIWK
CCCCEEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCEEEEE
EKEFEPSDIVDAYLVIAATNEPRVNEAVKQALPEHALFNNVGDASNGNVVFPSALHRDKL
CCCCCCHHHHEEEEEEEECCCCHHHHHHHHHCCHHHHHCCCCCCCCCCEEECCCCCCCEE
TISVSTDGASPKLTKSIMAELEALYPPSYSSYIDFLYTCRQKIKVLDITYNEKQQLLSQI
EEEEECCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCEEEEEEECHHHHHHHHH
VSQEYLNHDKQAQFLAWLDVR
HHHHHHCCCCHHEEEEEEECC
>Mature Secondary Structure
MNMPLMIDLTNKNVVIVGGGVVASRRAQTLNQYVEHMTVISPTITEKLQNMVDNGVVIWK
CCCCEEEEECCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCEEEEE
EKEFEPSDIVDAYLVIAATNEPRVNEAVKQALPEHALFNNVGDASNGNVVFPSALHRDKL
CCCCCCHHHHEEEEEEEECCCCHHHHHHHHHCCHHHHHCCCCCCCCCCEEECCCCCCCEE
TISVSTDGASPKLTKSIMAELEALYPPSYSSYIDFLYTCRQKIKVLDITYNEKQQLLSQI
EEEEECCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCEEEEEEECHHHHHHHHH
VSQEYLNHDKQAQFLAWLDVR
HHHHHHCCCCHHEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA