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The map label for this gene is betA

Identifier: 148269043

GI number: 148269043

Start: 2786218

End: 2787927

Strand: Reverse

Name: betA

Synonym: SaurJH9_2634

Alternate gene names: 148269043

Gene position: 2787927-2786218 (Counterclockwise)

Preceding gene: 148269044

Following gene: 148269042

Centisome position: 95.91

GC content: 38.77

Gene sequence:

>1710_bases
ATGAGTAACAAAAATAAATCATATGATTATGTCATCATTGGAGGAGGCAGTGCAGGTTCTGTACTAGGTAATCGTCTGAG
TGAAGATAAAGATAAAGAAGTCTTAGTATTAGAAGCGGGTCGCAGTGATTATTTTTGGGATTTATTTATCCAAATGCCTG
CTGCGTTAATGTTCCCTTCAGGCAATAAATTTTACGATTGGATTTATTCAACAGATGAAGAACCACATATGGGCGGTCGT
AAAGTAGCACATGCCCGAGGTAAAGTTTTAGGTGGATCAAGTTCGATTAATGGCATGATTTATCAACGTGGTAATCCAAT
GGACTATGAAGGCTGGGCAGAACCAGAAGGTATGGAAACTTGGGATTTTGCGCACTGTTTACCGTATTTTAAAAAATTAG
AAAAAACATACGGTGCAGCGCCTTATGATAAATTTAGAGGCCATGATGGACCAATTAAGTTAAAACGAGGGCCAGCAACG
AATCCTTTATTCCAGTCATTCTTTGATGCAGGTGTTGAAGCAGGTTATCATAAAACACCTGATGTGAATGGATTTAGACA
AGAAGGTTTTGGACCGTTCGATAGTCAAGTACATCGTGGTCGCCGAATGTCAGCTTCAAGAGCATATTTACATCCAGCGA
TGAAGCGTAAAAACTTAACCGTTGAAACACGTGCCTTTGTAACTGAAATTCATTATGAAGGTAGAAGAGCAACTGGTGTT
ACGTATAAGAAAAATGGCAAACTACATACCATCGATGCTAATGAAGTCATTTTGTCTGGTGGGGCATTCAATACGCCACA
ATTACTACAATTATCTGGTATCGGTGATTCAGAGTTCCTAAAATCAAAAGGCATTGAGCCACGTGTTCATTTACCAGGTG
TGGGTGAAAACTTTGAAGATCACTTAGAGGTATACATTCAACATAAATGTAAGGAACCTGTATCATTACAGCCAAGCTTA
GATATCAAGCGCATGCCATTTATTGGTTTACAATGGATTTTCACACGTACAGGTGCAGCAGCATCTAACCATTTTGAAGG
TGGCGGATTTGTACGTTCAAATAACGAAGTTGATTATCCTAACTTAATGTTCCATTTCTTACCAATAGCTGTAAGATATG
ATGGTCAAAAGGCAGCGGTCGCACATGGTTATCAAGTTCACGTAGGACCAATGTATTCAAACTCTCGTGGTAGCTTGAAA
ATCAAATCTAAAGATCCATTCGAAAAACCAAGTATCCGCTTTAATTATTTATCAACAGAAGAAGATAAAAAAGAATGGGT
AGAAGCAATTCGTGTAGCAAGAAATATCTTATCTCAAAAAGCAATGGATCCATTCAATGGTGGAGAAATTTCACCAGGAC
CAGAAGTGCAAACAGACGAAGAAATTCTTGATTGGGTTCGTAGAGATGGTGAAACAGCATTACACCCATCTTGTAGTGCT
AAAATGGGTCCTGCTTCAGATCCAATGGCAGTAGTTGACCCGTTAACAATGAAAGTCCACGGTATGGAAAATTTACGTGT
AGTTGATGCATCCGCTATGCCACGTACGACAAATGGCAATATACACGCACCTGTTTTAATGTTAGCTGAAAAAGCAGCAG
ACATTATACGTGGCAGAAAGCCTTTAGAGCCACAATATATTGATTATTATAAGCATGGTGTTCATGATGAAAATGAAGGT
GCAATCGAAGTAAAACCATACGCTAAATAA

Upstream 100 bases:

>100_bases
GTTAGCCAAGTTTAGCAATTCAACGATAACCAATCAGCCACTAACAAATATTTCATGCAATACTCACTTTGAAATACAAC
AAACTTTGGAGGTCATAACG

Downstream 100 bases:

>100_bases
ATTTATATAGTAGACTCTTAGTCTGGCATCTATTGTATTGGTGCCAGACTTTTTTGCGTTTTATCTAAATGAGAAGTTAA
TGTGTTGTTTAAAAACGGTG

Product: choline dehydrogenase

Products: NA

Alternate protein names: CDH; CHD

Number of amino acids: Translated: 569; Mature: 568

Protein sequence:

>569_residues
MSNKNKSYDYVIIGGGSAGSVLGNRLSEDKDKEVLVLEAGRSDYFWDLFIQMPAALMFPSGNKFYDWIYSTDEEPHMGGR
KVAHARGKVLGGSSSINGMIYQRGNPMDYEGWAEPEGMETWDFAHCLPYFKKLEKTYGAAPYDKFRGHDGPIKLKRGPAT
NPLFQSFFDAGVEAGYHKTPDVNGFRQEGFGPFDSQVHRGRRMSASRAYLHPAMKRKNLTVETRAFVTEIHYEGRRATGV
TYKKNGKLHTIDANEVILSGGAFNTPQLLQLSGIGDSEFLKSKGIEPRVHLPGVGENFEDHLEVYIQHKCKEPVSLQPSL
DIKRMPFIGLQWIFTRTGAAASNHFEGGGFVRSNNEVDYPNLMFHFLPIAVRYDGQKAAVAHGYQVHVGPMYSNSRGSLK
IKSKDPFEKPSIRFNYLSTEEDKKEWVEAIRVARNILSQKAMDPFNGGEISPGPEVQTDEEILDWVRRDGETALHPSCSA
KMGPASDPMAVVDPLTMKVHGMENLRVVDASAMPRTTNGNIHAPVLMLAEKAADIIRGRKPLEPQYIDYYKHGVHDENEG
AIEVKPYAK

Sequences:

>Translated_569_residues
MSNKNKSYDYVIIGGGSAGSVLGNRLSEDKDKEVLVLEAGRSDYFWDLFIQMPAALMFPSGNKFYDWIYSTDEEPHMGGR
KVAHARGKVLGGSSSINGMIYQRGNPMDYEGWAEPEGMETWDFAHCLPYFKKLEKTYGAAPYDKFRGHDGPIKLKRGPAT
NPLFQSFFDAGVEAGYHKTPDVNGFRQEGFGPFDSQVHRGRRMSASRAYLHPAMKRKNLTVETRAFVTEIHYEGRRATGV
TYKKNGKLHTIDANEVILSGGAFNTPQLLQLSGIGDSEFLKSKGIEPRVHLPGVGENFEDHLEVYIQHKCKEPVSLQPSL
DIKRMPFIGLQWIFTRTGAAASNHFEGGGFVRSNNEVDYPNLMFHFLPIAVRYDGQKAAVAHGYQVHVGPMYSNSRGSLK
IKSKDPFEKPSIRFNYLSTEEDKKEWVEAIRVARNILSQKAMDPFNGGEISPGPEVQTDEEILDWVRRDGETALHPSCSA
KMGPASDPMAVVDPLTMKVHGMENLRVVDASAMPRTTNGNIHAPVLMLAEKAADIIRGRKPLEPQYIDYYKHGVHDENEG
AIEVKPYAK
>Mature_568_residues
SNKNKSYDYVIIGGGSAGSVLGNRLSEDKDKEVLVLEAGRSDYFWDLFIQMPAALMFPSGNKFYDWIYSTDEEPHMGGRK
VAHARGKVLGGSSSINGMIYQRGNPMDYEGWAEPEGMETWDFAHCLPYFKKLEKTYGAAPYDKFRGHDGPIKLKRGPATN
PLFQSFFDAGVEAGYHKTPDVNGFRQEGFGPFDSQVHRGRRMSASRAYLHPAMKRKNLTVETRAFVTEIHYEGRRATGVT
YKKNGKLHTIDANEVILSGGAFNTPQLLQLSGIGDSEFLKSKGIEPRVHLPGVGENFEDHLEVYIQHKCKEPVSLQPSLD
IKRMPFIGLQWIFTRTGAAASNHFEGGGFVRSNNEVDYPNLMFHFLPIAVRYDGQKAAVAHGYQVHVGPMYSNSRGSLKI
KSKDPFEKPSIRFNYLSTEEDKKEWVEAIRVARNILSQKAMDPFNGGEISPGPEVQTDEEILDWVRRDGETALHPSCSAK
MGPASDPMAVVDPLTMKVHGMENLRVVDASAMPRTTNGNIHAPVLMLAEKAADIIRGRKPLEPQYIDYYKHGVHDENEGA
IEVKPYAK

Specific function: Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine

COG id: COG2303

COG function: function code E; Choline dehydrogenase and related flavoproteins

Gene ontology:

Cell location: Membrane-Bound [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GMC oxidoreductase family

Homologues:

Organism=Homo sapiens, GI217272839, Length=559, Percent_Identity=47.7638640429338, Blast_Score=519, Evalue=1e-147,
Organism=Escherichia coli, GI1786503, Length=550, Percent_Identity=49.4545454545455, Blast_Score=534, Evalue=1e-153,
Organism=Caenorhabditis elegans, GI17532301, Length=552, Percent_Identity=44.9275362318841, Blast_Score=493, Evalue=1e-139,
Organism=Drosophila melanogaster, GI24642048, Length=574, Percent_Identity=37.2822299651568, Blast_Score=301, Evalue=7e-82,
Organism=Drosophila melanogaster, GI24642042, Length=581, Percent_Identity=35.2839931153184, Blast_Score=293, Evalue=3e-79,
Organism=Drosophila melanogaster, GI45551458, Length=574, Percent_Identity=33.2752613240418, Blast_Score=273, Evalue=2e-73,
Organism=Drosophila melanogaster, GI45549471, Length=574, Percent_Identity=33.2752613240418, Blast_Score=273, Evalue=3e-73,
Organism=Drosophila melanogaster, GI24642059, Length=573, Percent_Identity=35.2530541012216, Blast_Score=270, Evalue=1e-72,
Organism=Drosophila melanogaster, GI24642055, Length=591, Percent_Identity=33.8409475465313, Blast_Score=261, Evalue=1e-69,
Organism=Drosophila melanogaster, GI24650267, Length=587, Percent_Identity=32.5383304940375, Blast_Score=241, Evalue=1e-63,
Organism=Drosophila melanogaster, GI18859995, Length=566, Percent_Identity=33.3922261484099, Blast_Score=241, Evalue=1e-63,
Organism=Drosophila melanogaster, GI24642039, Length=572, Percent_Identity=32.6923076923077, Blast_Score=239, Evalue=3e-63,
Organism=Drosophila melanogaster, GI17137792, Length=564, Percent_Identity=30.6737588652482, Blast_Score=231, Evalue=2e-60,
Organism=Drosophila melanogaster, GI24642051, Length=581, Percent_Identity=32.5301204819277, Blast_Score=226, Evalue=3e-59,
Organism=Drosophila melanogaster, GI18859993, Length=572, Percent_Identity=31.1188811188811, Blast_Score=214, Evalue=9e-56,
Organism=Drosophila melanogaster, GI24642037, Length=587, Percent_Identity=30.8347529812606, Blast_Score=207, Evalue=1e-53,
Organism=Drosophila melanogaster, GI24642035, Length=570, Percent_Identity=30.3508771929825, Blast_Score=206, Evalue=3e-53,
Organism=Drosophila melanogaster, GI24645930, Length=584, Percent_Identity=25.6849315068493, Blast_Score=122, Evalue=6e-28,
Organism=Drosophila melanogaster, GI24642057, Length=596, Percent_Identity=26.1744966442953, Blast_Score=114, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): BETA_STAA1 (A7X6Z3)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001443186.1
- ProteinModelPortal:   A7X6Z3
- SMR:   A7X6Z3
- STRING:   A7X6Z3
- EnsemblBacteria:   EBSTAT00000004006
- GeneID:   5561524
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_2596
- eggNOG:   COG2303
- GeneTree:   EBGT00050000024944
- HOGENOM:   HBG734713
- OMA:   RAAIRIT
- ProtClustDB:   PRK02106
- BioCyc:   SAUR418127:SAHV_2596-MONOMER
- HAMAP:   MF_00750
- InterPro:   IPR011533
- InterPro:   IPR012132
- InterPro:   IPR000172
- InterPro:   IPR007867
- PIRSF:   PIRSF000137
- TIGRFAMs:   TIGR01810

Pfam domain/function: PF05199 GMC_oxred_C; PF00732 GMC_oxred_N

EC number: =1.1.99.1

Molecular weight: Translated: 63611; Mature: 63480

Theoretical pI: Translated: 7.41; Mature: 7.41

Prosite motif: PS00623 GMC_OXRED_1; PS00624 GMC_OXRED_2

Important sites: ACT_SITE 475-475

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNKNKSYDYVIIGGGSAGSVLGNRLSEDKDKEVLVLEAGRSDYFWDLFIQMPAALMFPS
CCCCCCCCCEEEEECCCCHHHHHHHCCCCCCCEEEEEECCCCCCEEHHHHHCCCEEECCC
GNKFYDWIYSTDEEPHMGGRKVAHARGKVLGGSSSINGMIYQRGNPMDYEGWAEPEGMET
CCCEEEEEECCCCCCCCCCCHHHHHCCCEECCCCCCCEEEEECCCCCCCCCCCCCCCCCC
WDFAHCLPYFKKLEKTYGAAPYDKFRGHDGPIKLKRGPATNPLFQSFFDAGVEAGYHKTP
HHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCCC
DVNGFRQEGFGPFDSQVHRGRRMSASRAYLHPAMKRKNLTVETRAFVTEIHYEGRRATGV
CCCCHHHCCCCCCHHHHHCCCCCCCHHHHHHHHHHHCCCEEEHHHEEEEHEECCCEECCC
TYKKNGKLHTIDANEVILSGGAFNTPQLLQLSGIGDSEFLKSKGIEPRVHLPGVGENFED
EEECCCCEEEEECCEEEEECCCCCCCCEEEEECCCCHHHHHHCCCCCEEECCCCCCCHHH
HLEVYIQHKCKEPVSLQPSLDIKRMPFIGLQWIFTRTGAAASNHFEGGGFVRSNNEVDYP
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCEEECCCCCCCH
NLMFHFLPIAVRYDGQKAAVAHGYQVHVGPMYSNSRGSLKIKSKDPFEKPSIRFNYLSTE
HHHHEEEEEEEEECCCEEEEECCEEEEECCEEECCCCCEEECCCCCCCCCCEEEEEECCC
EDKKEWVEAIRVARNILSQKAMDPFNGGEISPGPEVQTDEEILDWVRRDGETALHPSCSA
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEECCCCCC
KMGPASDPMAVVDPLTMKVHGMENLRVVDASAMPRTTNGNIHAPVLMLAEKAADIIRGRK
CCCCCCCCCEEECCEEEEEECCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCC
PLEPQYIDYYKHGVHDENEGAIEVKPYAK
CCCCHHHHHHHCCCCCCCCCEEEECCCCC
>Mature Secondary Structure 
SNKNKSYDYVIIGGGSAGSVLGNRLSEDKDKEVLVLEAGRSDYFWDLFIQMPAALMFPS
CCCCCCCCEEEEECCCCHHHHHHHCCCCCCCEEEEEECCCCCCEEHHHHHCCCEEECCC
GNKFYDWIYSTDEEPHMGGRKVAHARGKVLGGSSSINGMIYQRGNPMDYEGWAEPEGMET
CCCEEEEEECCCCCCCCCCCHHHHHCCCEECCCCCCCEEEEECCCCCCCCCCCCCCCCCC
WDFAHCLPYFKKLEKTYGAAPYDKFRGHDGPIKLKRGPATNPLFQSFFDAGVEAGYHKTP
HHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCCC
DVNGFRQEGFGPFDSQVHRGRRMSASRAYLHPAMKRKNLTVETRAFVTEIHYEGRRATGV
CCCCHHHCCCCCCHHHHHCCCCCCCHHHHHHHHHHHCCCEEEHHHEEEEHEECCCEECCC
TYKKNGKLHTIDANEVILSGGAFNTPQLLQLSGIGDSEFLKSKGIEPRVHLPGVGENFED
EEECCCCEEEEECCEEEEECCCCCCCCEEEEECCCCHHHHHHCCCCCEEECCCCCCCHHH
HLEVYIQHKCKEPVSLQPSLDIKRMPFIGLQWIFTRTGAAASNHFEGGGFVRSNNEVDYP
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCEEECCCCCCCH
NLMFHFLPIAVRYDGQKAAVAHGYQVHVGPMYSNSRGSLKIKSKDPFEKPSIRFNYLSTE
HHHHEEEEEEEEECCCEEEEECCEEEEECCEEECCCCCEEECCCCCCCCCCEEEEEECCC
EDKKEWVEAIRVARNILSQKAMDPFNGGEISPGPEVQTDEEILDWVRRDGETALHPSCSA
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEECCCCCC
KMGPASDPMAVVDPLTMKVHGMENLRVVDASAMPRTTNGNIHAPVLMLAEKAADIIRGRK
CCCCCCCCCEEECCEEEEEECCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCC
PLEPQYIDYYKHGVHDENEGAIEVKPYAK
CCCCHHHHHHHCCCCCCCCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA