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The map label for this gene is panC

Identifier: 148269029

GI number: 148269029

Start: 2770977

End: 2771828

Strand: Reverse

Name: panC

Synonym: SaurJH9_2620

Alternate gene names: 148269029

Gene position: 2771828-2770977 (Counterclockwise)

Preceding gene: 148269030

Following gene: 148269028

Centisome position: 95.36

GC content: 36.27

Gene sequence:

>852_bases
ATGACTAAGCTGATTACTACGGTAAAAGAGATGCAACACATTGTTAAAGCAGCCAAACGCTCAGGAACAACGATTGGTTT
TATCCCAACAATGGGTGCCTTACATGATGGACATTTAACGATGGTACGCGAATCAGTTAGTACAAATGATATTACAGTTG
TGAGTGTATTTGTTAATCCATTACAATTTGGTCCAAACGAAGATTTCGATGCTTATCCGAGACAAATTGATAAAGATTTA
GAATTAGTATCAGAAGTAGGGGCGGACATTGTTTTTCATCCTGCAGTAGAAGATATATATCCAGGTGAATTAGGTATTGA
TGTCAAAGTAGGTCCATTAGCTGATGTGTTAGAAGGAGCGAAGCGTCCAGGGCATTTTGATGGGGTGGTAACAGTAGTTA
ATAAGCTATTTAATATTGTTATGCCGGATTATGCTTATTTTGGTAAAAAAGATGCCCAGCAATTGGCTATTGTCGAGCAA
ATGGTAAAAGACTTCAATCATGCCGTTGAAATTATTGGTATTGATATCGTTCGAGAAGCAGATGGTTTGGCGAAAAGTTC
AAGAAATGTTTATTTAACGGAGCAAGAACGACAAGAAGCGGTACATTTAAGTAAAAGTTTGCTATTAGCACAAGCGTTGT
ATCAAGACGGTGAACGTCAAAGTAAAGTAATTATAGACAGGGTTACTGAATATCTTGAATCACATATAAGTGGACGCATT
GAAGAAGTTGCTGTTTATAGTTATCCTCAATTAGTAGAACAACACGAAATAACTGGACGCATATTTATCTCGTTAGCTGT
CAAATTTTCAAAAGCGCGTTTAATAGATAATATAATAATTGGAGCTGAATAA

Upstream 100 bases:

>100_bases
GTGGATGGTTTAAAACAATACGATCAAGAAGTTAAATCTGGTGCATTTCCATCAGAAGAATATACGTATAAAAAGAAAAT
TATGAATGAGGTTAATAACA

Downstream 100 bases:

>100_bases
AGTGATAAGAACAATGATGAATGCTAAAATTCATAGAGCAAGAGTGACTGAGTCAAATTTAAATTATGTAGGTAGTATTA
CGATTGATTCAGATATTTTG

Product: pantoate--beta-alanine ligase

Products: NA

Alternate protein names: PS; Pantoate--beta-alanine ligase; Pantoate-activating enzyme

Number of amino acids: Translated: 283; Mature: 282

Protein sequence:

>283_residues
MTKLITTVKEMQHIVKAAKRSGTTIGFIPTMGALHDGHLTMVRESVSTNDITVVSVFVNPLQFGPNEDFDAYPRQIDKDL
ELVSEVGADIVFHPAVEDIYPGELGIDVKVGPLADVLEGAKRPGHFDGVVTVVNKLFNIVMPDYAYFGKKDAQQLAIVEQ
MVKDFNHAVEIIGIDIVREADGLAKSSRNVYLTEQERQEAVHLSKSLLLAQALYQDGERQSKVIIDRVTEYLESHISGRI
EEVAVYSYPQLVEQHEITGRIFISLAVKFSKARLIDNIIIGAE

Sequences:

>Translated_283_residues
MTKLITTVKEMQHIVKAAKRSGTTIGFIPTMGALHDGHLTMVRESVSTNDITVVSVFVNPLQFGPNEDFDAYPRQIDKDL
ELVSEVGADIVFHPAVEDIYPGELGIDVKVGPLADVLEGAKRPGHFDGVVTVVNKLFNIVMPDYAYFGKKDAQQLAIVEQ
MVKDFNHAVEIIGIDIVREADGLAKSSRNVYLTEQERQEAVHLSKSLLLAQALYQDGERQSKVIIDRVTEYLESHISGRI
EEVAVYSYPQLVEQHEITGRIFISLAVKFSKARLIDNIIIGAE
>Mature_282_residues
TKLITTVKEMQHIVKAAKRSGTTIGFIPTMGALHDGHLTMVRESVSTNDITVVSVFVNPLQFGPNEDFDAYPRQIDKDLE
LVSEVGADIVFHPAVEDIYPGELGIDVKVGPLADVLEGAKRPGHFDGVVTVVNKLFNIVMPDYAYFGKKDAQQLAIVEQM
VKDFNHAVEIIGIDIVREADGLAKSSRNVYLTEQERQEAVHLSKSLLLAQALYQDGERQSKVIIDRVTEYLESHISGRIE
EVAVYSYPQLVEQHEITGRIFISLAVKFSKARLIDNIIIGAE

Specific function: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate

COG id: COG0414

COG function: function code H; Panthothenate synthetase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pantothenate synthetase family

Homologues:

Organism=Escherichia coli, GI1786325, Length=279, Percent_Identity=41.5770609318996, Blast_Score=211, Evalue=6e-56,
Organism=Saccharomyces cerevisiae, GI6322046, Length=289, Percent_Identity=39.4463667820069, Blast_Score=183, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PANC_STAA1 (A7X6X6)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001443172.1
- ProteinModelPortal:   A7X6X6
- SMR:   A7X6X6
- STRING:   A7X6X6
- EnsemblBacteria:   EBSTAT00000005001
- GeneID:   5560872
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_2582
- eggNOG:   COG0414
- GeneTree:   EBGT00050000024787
- HOGENOM:   HBG428839
- OMA:   RLIDNFT
- ProtClustDB:   PRK00380
- BioCyc:   SAUR418127:SAHV_2582-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00158
- InterPro:   IPR003721
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR21299:SF1
- TIGRFAMs:   TIGR00018

Pfam domain/function: PF02569 Pantoate_ligase

EC number: =6.3.2.1

Molecular weight: Translated: 31430; Mature: 31299

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: ACT_SITE 38-38 BINDING 62-62 BINDING 62-62 BINDING 154-154 BINDING 177-177

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKLITTVKEMQHIVKAAKRSGTTIGFIPTMGALHDGHLTMVRESVSTNDITVVSVFVNP
CCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHCCCCCEEEEEEEECH
LQFGPNEDFDAYPRQIDKDLELVSEVGADIVFHPAVEDIYPGELGIDVKVGPLADVLEGA
HHCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCHHHCCCCCCCCEEEECCHHHHHHCC
KRPGHFDGVVTVVNKLFNIVMPDYAYFGKKDAQQLAIVEQMVKDFNHAVEIIGIDIVREA
CCCCCCHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DGLAKSSRNVYLTEQERQEAVHLSKSLLLAQALYQDGERQSKVIIDRVTEYLESHISGRI
HHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCH
EEVAVYSYPQLVEQHEITGRIFISLAVKFSKARLIDNIIIGAE
HHHHHHCCHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHEECCC
>Mature Secondary Structure 
TKLITTVKEMQHIVKAAKRSGTTIGFIPTMGALHDGHLTMVRESVSTNDITVVSVFVNP
CHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHCCCCCEEEEEEEECH
LQFGPNEDFDAYPRQIDKDLELVSEVGADIVFHPAVEDIYPGELGIDVKVGPLADVLEGA
HHCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCHHHCCCCCCCCEEEECCHHHHHHCC
KRPGHFDGVVTVVNKLFNIVMPDYAYFGKKDAQQLAIVEQMVKDFNHAVEIIGIDIVREA
CCCCCCHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DGLAKSSRNVYLTEQERQEAVHLSKSLLLAQALYQDGERQSKVIIDRVTEYLESHISGRI
HHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCH
EEVAVYSYPQLVEQHEITGRIFISLAVKFSKARLIDNIIIGAE
HHHHHHCCHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA