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The map label for this gene is yeiR [C]

Identifier: 148269013

GI number: 148269013

Start: 2756596

End: 2757486

Strand: Reverse

Name: yeiR [C]

Synonym: SaurJH9_2604

Alternate gene names: 148269013

Gene position: 2757486-2756596 (Counterclockwise)

Preceding gene: 148269014

Following gene: 148269008

Centisome position: 94.87

GC content: 35.35

Gene sequence:

>891_bases
ATGAAAATAGTTATTATAGGTGGGTTTTTAGGTGGCGGTAAAACGACTGTCTTAAATCATTTGCTCGCTGAATCATTAAA
GGAATCGCTGAAACCAGCAGTCATCATGAATGAATTTGGGAAAATGAGTGTTGATGGTGCCTTAGTATCTGAAGACATAC
CTTTAAGTGAACTGACAGAGGGGTGTATCTGTTGCGCAATGAAAGCAGATGTATCAGAACAGTTACATCAATTATATTTA
AAAGAGCAACCAGACATTGTATTTATTGAATGTAGTGGGATTGCAGAACCAGTCTCTGTCTTAGATGCTTGTTTAACGCC
TATTTTAGCTCCGTTTACAACAATTACACATATGATTGGTGTAATAGACGCAAGCATGTATAAACACATTAAATCATTCC
CTAAAGACATCCAAGGCTTATTTTATGAGCAATTAGCATATTGTTCTGTCTTATTTGTTAATAAAATAGATTCAGCAGAT
GTTGAAACAACGAGCAAACTATTGAAAGATTTAGAAGTTATTAACCCAGAGGCCGATATACAAGTCGGTATGCATGGCAG
CGTCACTTTGCCAATATCAGTTAGACAAATGACAGCAACTTCTGACAATAAACATGAATCATTACACAAAACAATAAATC
ATCAATTTGTGCAATCACCAGTCACATGTACTAAAGCAGAGTTTATAAAACGTTTAGCATGCCTTCCGTCTCATATTTAT
AGGTTGAAAGGGTTTATGACATTTGAAGACACCACACATACGTATCTCATTCAATTTACACAAGGCCAATATGAATTAAC
ACCTGTAGCATTTTCAAAAAAAGTGCCAGAATATTTGGTGCTTATCGGAAAGGGTATTTCAAAAGAAGACTATCAATGTT
TGGAACAGTAG

Upstream 100 bases:

>100_bases
TTAAAAAAATGAACTATAACTGAATATAGAGTCATGTCAGTCAATAGGAGATCTATCTTGGAATATGCTATTCATATGAA
GTATAAGAGGAGAGTCGCAG

Downstream 100 bases:

>100_bases
TGTTTTCAGTGGAAGAGAATGGTTAACATGCCTTCATGTATAATAACGAGTTGATTTGAACGTTTAAACGTAAACAAAAA
TAAGCTTGGTCAGCCATCAA

Product: cobalamin synthesis protein, P47K

Products: NA

Alternate protein names: P47K [H]

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MKIVIIGGFLGGGKTTVLNHLLAESLKESLKPAVIMNEFGKMSVDGALVSEDIPLSELTEGCICCAMKADVSEQLHQLYL
KEQPDIVFIECSGIAEPVSVLDACLTPILAPFTTITHMIGVIDASMYKHIKSFPKDIQGLFYEQLAYCSVLFVNKIDSAD
VETTSKLLKDLEVINPEADIQVGMHGSVTLPISVRQMTATSDNKHESLHKTINHQFVQSPVTCTKAEFIKRLACLPSHIY
RLKGFMTFEDTTHTYLIQFTQGQYELTPVAFSKKVPEYLVLIGKGISKEDYQCLEQ

Sequences:

>Translated_296_residues
MKIVIIGGFLGGGKTTVLNHLLAESLKESLKPAVIMNEFGKMSVDGALVSEDIPLSELTEGCICCAMKADVSEQLHQLYL
KEQPDIVFIECSGIAEPVSVLDACLTPILAPFTTITHMIGVIDASMYKHIKSFPKDIQGLFYEQLAYCSVLFVNKIDSAD
VETTSKLLKDLEVINPEADIQVGMHGSVTLPISVRQMTATSDNKHESLHKTINHQFVQSPVTCTKAEFIKRLACLPSHIY
RLKGFMTFEDTTHTYLIQFTQGQYELTPVAFSKKVPEYLVLIGKGISKEDYQCLEQ
>Mature_296_residues
MKIVIIGGFLGGGKTTVLNHLLAESLKESLKPAVIMNEFGKMSVDGALVSEDIPLSELTEGCICCAMKADVSEQLHQLYL
KEQPDIVFIECSGIAEPVSVLDACLTPILAPFTTITHMIGVIDASMYKHIKSFPKDIQGLFYEQLAYCSVLFVNKIDSAD
VETTSKLLKDLEVINPEADIQVGMHGSVTLPISVRQMTATSDNKHESLHKTINHQFVQSPVTCTKAEFIKRLACLPSHIY
RLKGFMTFEDTTHTYLIQFTQGQYELTPVAFSKKVPEYLVLIGKGISKEDYQCLEQ

Specific function: The presence of P47K is critical for the expression of the nitrile hydratase genes. May stabilize or activate the nitrile hydratase proteins [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI33469141, Length=334, Percent_Identity=29.0419161676647, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI126722884, Length=334, Percent_Identity=29.0419161676647, Blast_Score=88, Evalue=9e-18,
Organism=Homo sapiens, GI148727351, Length=334, Percent_Identity=29.0419161676647, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI146231952, Length=337, Percent_Identity=29.3768545994065, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI223941779, Length=322, Percent_Identity=27.9503105590062, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI223941776, Length=326, Percent_Identity=28.5276073619632, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI119120938, Length=303, Percent_Identity=27.0627062706271, Blast_Score=74, Evalue=1e-13,
Organism=Escherichia coli, GI1788499, Length=188, Percent_Identity=30.3191489361702, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI87082430, Length=198, Percent_Identity=30.3030303030303, Blast_Score=76, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 32810; Mature: 32810

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIVIIGGFLGGGKTTVLNHLLAESLKESLKPAVIMNEFGKMSVDGALVSEDIPLSELTE
CEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCEEECCCCCHHHHHH
GCICCAMKADVSEQLHQLYLKEQPDIVFIECSGIAEPVSVLDACLTPILAPFTTITHMIG
HHEEHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VIDASMYKHIKSFPKDIQGLFYEQLAYCSVLFVNKIDSADVETTSKLLKDLEVINPEADI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCE
QVGMHGSVTLPISVRQMTATSDNKHESLHKTINHQFVQSPVTCTKAEFIKRLACLPSHIY
EECCCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
RLKGFMTFEDTTHTYLIQFTQGQYELTPVAFSKKVPEYLVLIGKGISKEDYQCLEQ
HHHCCEEECCCCEEEEEEEECCCEEEEHHHHHHCCCHHHEEECCCCCHHHHHHHCC
>Mature Secondary Structure
MKIVIIGGFLGGGKTTVLNHLLAESLKESLKPAVIMNEFGKMSVDGALVSEDIPLSELTE
CEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCEEECCCCCHHHHHH
GCICCAMKADVSEQLHQLYLKEQPDIVFIECSGIAEPVSVLDACLTPILAPFTTITHMIG
HHEEHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VIDASMYKHIKSFPKDIQGLFYEQLAYCSVLFVNKIDSADVETTSKLLKDLEVINPEADI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCE
QVGMHGSVTLPISVRQMTATSDNKHESLHKTINHQFVQSPVTCTKAEFIKRLACLPSHIY
EECCCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
RLKGFMTFEDTTHTYLIQFTQGQYELTPVAFSKKVPEYLVLIGKGISKEDYQCLEQ
HHHCCEEECCCCEEEEEEEECCCEEEEHHHHHHCCCHHHEEECCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2013568 [H]