Click here to switch to the map view.

The map label for this gene is isaA

Identifier: 148269000

GI number: 148269000

Start: 2746779

End: 2747480

Strand: Reverse

Name: isaA

Synonym: SaurJH9_2591

Alternate gene names: 148269000

Gene position: 2747480-2746779 (Counterclockwise)

Preceding gene: 148269001

Following gene: 148268999

Centisome position: 94.52

GC content: 41.74

Gene sequence:

>702_bases
ATGAAAAAGACAATTATGGCATCATCATTAGCAGTGGCATTAGGTGTAACAGGTTACGCAGCAGGTACAGGACATCAAGC
ACACGCTGCTGAAGTAAACGTTGATCAAGCACACTTAGTTGACTTAGCGCATAATCACCAAGATCAATTAAATGCAGCTC
CAATCAAAGATGGTGCATATGACATCCACTTTGTAAAAGATGGTTTCCAATATAACTTTACTTCAAATGGTACTACATGG
TCATGGAGCTATGAAGCAGCTAATGGTCAAACTGCTGGTTTCTCAAACGTTGCAGGTGCAGACTACACTACTTCATACAA
CCAAGGTTCAGATGTACAATCAGTAAGCTACAATGCACAATCAAGTAACTCAAACGTTGAAGCTGTTTCAGCTCCAACTT
ACCATAACTACAGCACTTCAACTACTTCAAGTTCAGTGAGATTAAGCAATGGTAATACTGCAGGTGCTACTGGTTCATCA
GCAGCTCAAATCATGGCTCAACGTACTGGTGTTTCAGCTTCTACATGGGCTGCAATCATCGCTCGTGAATCAAATGGTCA
AGTAAATGCTTACAACCCATCAGGTGCTTCAGGTTTATTCCAAACTATGCCAGGTTGGGGTCCGACAAACACTGTTGACC
AACAAATCAACGCAGCTGTTAAAGCATACAAAGCACAAGGTTTAGGTGCTTGGGGATTCTAA

Upstream 100 bases:

>100_bases
AAGAAATAAAAGACAATTTAAACTTGCACTACGACATTCAAATTCAAAATATAATTACTAAAAACATAAACTTACAATTA
TTACTGGAGGATTTTTTACT

Downstream 100 bases:

>100_bases
TTCCTTCATAATAAATAAAAGTAATGTTTAGACATTAAATATATAGCTCTTCCCATAGAAATTGGGGAGAGTTTTTTTAT
TAATTAAAAATACATTTCTT

Product: transglycosylase domain-containing protein

Products: NA

Alternate protein names: Immunodominant staphylococcal antigen A

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MKKTIMASSLAVALGVTGYAAGTGHQAHAAEVNVDQAHLVDLAHNHQDQLNAAPIKDGAYDIHFVKDGFQYNFTSNGTTW
SWSYEAANGQTAGFSNVAGADYTTSYNQGSDVQSVSYNAQSSNSNVEAVSAPTYHNYSTSTTSSSVRLSNGNTAGATGSS
AAQIMAQRTGVSASTWAAIIARESNGQVNAYNPSGASGLFQTMPGWGPTNTVDQQINAAVKAYKAQGLGAWGF

Sequences:

>Translated_233_residues
MKKTIMASSLAVALGVTGYAAGTGHQAHAAEVNVDQAHLVDLAHNHQDQLNAAPIKDGAYDIHFVKDGFQYNFTSNGTTW
SWSYEAANGQTAGFSNVAGADYTTSYNQGSDVQSVSYNAQSSNSNVEAVSAPTYHNYSTSTTSSSVRLSNGNTAGATGSS
AAQIMAQRTGVSASTWAAIIARESNGQVNAYNPSGASGLFQTMPGWGPTNTVDQQINAAVKAYKAQGLGAWGF
>Mature_233_residues
MKKTIMASSLAVALGVTGYAAGTGHQAHAAEVNVDQAHLVDLAHNHQDQLNAAPIKDGAYDIHFVKDGFQYNFTSNGTTW
SWSYEAANGQTAGFSNVAGADYTTSYNQGSDVQSVSYNAQSSNSNVEAVSAPTYHNYSTSTTSSSVRLSNGNTAGATGSS
AAQIMAQRTGVSASTWAAIIARESNGQVNAYNPSGASGLFQTMPGWGPTNTVDQQINAAVKAYKAQGLGAWGF

Specific function: Is able to cleave peptidoglycan

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transglycosylase family. IsaA subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ISAA_STAA1 (A7X6T9)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001443143.1
- ProteinModelPortal:   A7X6T9
- SMR:   A7X6T9
- EnsemblBacteria:   EBSTAT00000004997
- GeneID:   5559739
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_2553
- eggNOG:   NOG13032
- GeneTree:   EBGT00050000023704
- HOGENOM:   HBG693910
- OMA:   INYANSR
- ProtClustDB:   CLSK886077
- BioCyc:   SAUR418127:SAHV_2553-MONOMER
- InterPro:   IPR010618

Pfam domain/function: PF06737 Transglycosylas

EC number: NA

Molecular weight: Translated: 24204; Mature: 24204

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTIMASSLAVALGVTGYAAGTGHQAHAAEVNVDQAHLVDLAHNHQDQLNAAPIKDGAY
CCCCHHHHHHEEEHCCCEEECCCCCCCEEEECCCCHHHHHHHHHCCCHHCCCCCCCCCCE
DIHFVKDGFQYNFTSNGTTWSWSYEAANGQTAGFSNVAGADYTTSYNQGSDVQSVSYNAQ
EEEEEECCEEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCEECCCCCCCCCEEEEECCC
SSNSNVEAVSAPTYHNYSTSTTSSSVRLSNGNTAGATGSSAAQIMAQRTGVSASTWAAII
CCCCCEEEEECCCCCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHCCCCHHHEEEEE
ARESNGQVNAYNPSGASGLFQTMPGWGPTNTVDQQINAAVKAYKAQGLGAWGF
EECCCCEEEEECCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKKTIMASSLAVALGVTGYAAGTGHQAHAAEVNVDQAHLVDLAHNHQDQLNAAPIKDGAY
CCCCHHHHHHEEEHCCCEEECCCCCCCEEEECCCCHHHHHHHHHCCCHHCCCCCCCCCCE
DIHFVKDGFQYNFTSNGTTWSWSYEAANGQTAGFSNVAGADYTTSYNQGSDVQSVSYNAQ
EEEEEECCEEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCEECCCCCCCCCEEEEECCC
SSNSNVEAVSAPTYHNYSTSTTSSSVRLSNGNTAGATGSSAAQIMAQRTGVSASTWAAII
CCCCCEEEEECCCCCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHCCCCHHHEEEEE
ARESNGQVNAYNPSGASGLFQTMPGWGPTNTVDQQINAAVKAYKAQGLGAWGF
EECCCCEEEEECCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA