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The map label for this gene is cidB

Identifier: 148268973

GI number: 148268973

Start: 2712490

End: 2713179

Strand: Reverse

Name: cidB

Synonym: SaurJH9_2563

Alternate gene names: 148268973

Gene position: 2713179-2712490 (Counterclockwise)

Preceding gene: 148268974

Following gene: 148268972

Centisome position: 93.34

GC content: 34.06

Gene sequence:

>690_bases
ATGAATGATTACGTGCAAGCCTTATTAATGATTTTGTTGACTGTCGTTTTATATTATTTCGCTAAAAGGTTACAACAAAA
ATATCCGAACCCATTTTTGAATCCAGCATTAATTGCATCTTTAGGAATTATTTTTGTCTTACTTATCTTTGGAATTAGTT
ATAACGGGTATATGAAAGGTGGCAGTTGGATCAACCATATTTTAAACGCAACGGTCGTATGTTTAGCGTACCCACTTTAT
AAAAATAGAGAGAAAATTAAAGACAATGTCTCTATCATTTTTGCAAGTGTATTAACTGGCGTCATGCTGAATTTCATGTT
AGTGTTCTTAACACTTAAAGCATTTGGCTATTCTAAAGACGTCATTGTAACGTTATTGCCCCGATCTATAACAGCCGCAG
TAGGTATCGAAGTGTCACATGAACTAGGTGGTACAGATACGATGACCGTACTTTTTATTATCACAACGGGTTTAATCGGT
AGTATTTTAGGTTCGATGTTATTAAGATTTGGAAGATTTGAATCTTCTATCGCCAAAGGTTTAACGTATGGGAATGCGTC
ACATGCATTTGGCACAGCTAAAGCACTAGAAATGGATATTGAATCCGGTGCATTTAGTTCAATTGGGATGATTTTAACTG
CAGTTATTAGTTCAGTGTTAATACCTGTTCTAATTTTATTATTCTATTAA

Upstream 100 bases:

>100_bases
GCAGTCATTATTATAGGAACATGTATCGTTGCATTATCTTCAGGTTATATTGCTGAAAAAATGTCTGTTAAACATAAACA
TCGTAAAGGTGTAGACGCTT

Downstream 100 bases:

>100_bases
TTTAGATATTTAAAATGATAGACACTAAGAAAGGGAGGCTATTAGTAATAATGGCAAAAATAAAAGCAAATGAAGCATTA
GTTAAAGCATTACAAGCATG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MNDYVQALLMILLTVVLYYFAKRLQQKYPNPFLNPALIASLGIIFVLLIFGISYNGYMKGGSWINHILNATVVCLAYPLY
KNREKIKDNVSIIFASVLTGVMLNFMLVFLTLKAFGYSKDVIVTLLPRSITAAVGIEVSHELGGTDTMTVLFIITTGLIG
SILGSMLLRFGRFESSIAKGLTYGNASHAFGTAKALEMDIESGAFSSIGMILTAVISSVLIPVLILLFY

Sequences:

>Translated_229_residues
MNDYVQALLMILLTVVLYYFAKRLQQKYPNPFLNPALIASLGIIFVLLIFGISYNGYMKGGSWINHILNATVVCLAYPLY
KNREKIKDNVSIIFASVLTGVMLNFMLVFLTLKAFGYSKDVIVTLLPRSITAAVGIEVSHELGGTDTMTVLFIITTGLIG
SILGSMLLRFGRFESSIAKGLTYGNASHAFGTAKALEMDIESGAFSSIGMILTAVISSVLIPVLILLFY
>Mature_229_residues
MNDYVQALLMILLTVVLYYFAKRLQQKYPNPFLNPALIASLGIIFVLLIFGISYNGYMKGGSWINHILNATVVCLAYPLY
KNREKIKDNVSIIFASVLTGVMLNFMLVFLTLKAFGYSKDVIVTLLPRSITAAVGIEVSHELGGTDTMTVLFIITTGLIG
SILGSMLLRFGRFESSIAKGLTYGNASHAFGTAKALEMDIESGAFSSIGMILTAVISSVLIPVLILLFY

Specific function: Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidAB proteins.

COG id: COG1346

COG function: function code M; Putative effector of murein hydrolase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CidB/LrgB family. CidB subfamily

Homologues:

Organism=Escherichia coli, GI1788464, Length=220, Percent_Identity=34.5454545454545, Blast_Score=145, Evalue=3e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CIDB_STAA8 (P60639)

Other databases:

- EMBL:   CP000253
- RefSeq:   YP_501307.1
- STRING:   P60639
- EnsemblBacteria:   EBSTAT00000029213
- GeneID:   3921523
- GenomeReviews:   CP000253_GR
- KEGG:   sao:SAOUHSC_02850
- eggNOG:   COG1346
- GeneTree:   EBGT00050000024994
- HOGENOM:   HBG363009
- OMA:   PYKTYFD
- ProtClustDB:   CLSK886054
- BioCyc:   SAUR93061:SAOUHSC_02850-MONOMER
- GO:   GO:0019835
- InterPro:   IPR007300

Pfam domain/function: PF04172 LrgB

EC number: NA

Molecular weight: Translated: 25012; Mature: 25012

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x10cfacf4)-; HASH(0xc26f5b8)-; HASH(0x116b059c)-; HASH(0x119b9de0)-; HASH(0x115b580c)-; HASH(0x10e54ce0)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDYVQALLMILLTVVLYYFAKRLQQKYPNPFLNPALIASLGIIFVLLIFGISYNGYMKG
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
GSWINHILNATVVCLAYPLYKNREKIKDNVSIIFASVLTGVMLNFMLVFLTLKAFGYSKD
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
VIVTLLPRSITAAVGIEVSHELGGTDTMTVLFIITTGLIGSILGSMLLRFGRFESSIAKG
HHHHEHHHHHHHHHCCEEHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LTYGNASHAFGTAKALEMDIESGAFSSIGMILTAVISSVLIPVLILLFY
CCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
>Mature Secondary Structure
MNDYVQALLMILLTVVLYYFAKRLQQKYPNPFLNPALIASLGIIFVLLIFGISYNGYMKG
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
GSWINHILNATVVCLAYPLYKNREKIKDNVSIIFASVLTGVMLNFMLVFLTLKAFGYSKD
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
VIVTLLPRSITAAVGIEVSHELGGTDTMTVLFIITTGLIGSILGSMLLRFGRFESSIAKG
HHHHEHHHHHHHHHCCEEHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LTYGNASHAFGTAKALEMDIESGAFSSIGMILTAVISSVLIPVLILLFY
CCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA