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The map label for this gene is kdpD [H]

Identifier: 148266503

GI number: 148266503

Start: 67853

End: 70522

Strand: Reverse

Name: kdpD [H]

Synonym: SaurJH9_0058

Alternate gene names: 148266503

Gene position: 70522-67853 (Counterclockwise)

Preceding gene: 148266507

Following gene: 148266502

Centisome position: 2.43

GC content: 36.63

Gene sequence:

>2670_bases
ATGGAAAGTACATATAAAAAAAGAGGGAAACTTACCATTTATTTAGGCTATAGCCCAGGGGTAGGTAAAACGTATGAAAT
GTTATCAAATGGTATTGATCAGTATCAAGAAGGTGCAGATATTAAAATTGGTTATATCGAACCCCATCAACGCCCTGAAA
CCAATGCACTGGTTCAACAATTGCCTGAAATTTCGACCTCCAGCCGTAAATTTGGCAGCCACACCTTTCACTATATAGAT
GTCTCTAAAATCATAGAAGCTAATCCAGATGTGGTCTTAATTGATGAACTAGCACATACAAACATTTCAAAAGAGCGCCA
TTTAAAACGTTATAAGGATATAGAAGAAATTCTATCGCATGGTATCGATGTCTGGACAACACTCAACATCCAACATATCG
AGAGTCTAAGCGGACAAATTGCGTTAATGACAGGTATTCAAGTTACAGAACGTGTGCCCGACCAATTCATTACGTCAGCA
GATGCCTTTGAAGTTGTGGATATTTCACCAAATATGTTGATTCAGCGCCTTAAAGCAGGAAAAGTATATAAAAAAGAACG
CTTAGAAACAGCCTTTTCTAATTTCTTTACGTATGAAAATCTGACAGAGCTGCGTGAACTTACACTCAGAACTGTCGCAG
ATATTATGAGTCAAAAAGGACAACAATATAAAACTAAACATACCGACATTACACCGCATATTGCGGTAGCTATCAGCGGC
AGTATTTATAACGAACGGGTCATACGAGAAGCAAGACGTGCTGCCTATAAAGAACATGCTAAATTCACAGCTGTGTATAT
TGATGTCTTTGAGACACCGTCAGAAAGCAGAAAACAAGATCATTATGTCCATAAAAATCTAATGCTCGCCAAAGCGTTAG
GTGCAGAAATCAAAGTGTTGTATGCACAAGATATTGCGAAAGCGTTAACCGATTGGTGTGATCTCGCTTTTGTGACGAAG
CTAGTCCTTGGACAGTCAGAACAGCCACGTTGGAAAGATTACTTTAAACAGTCACTCATTGAACAAATTAATCACGTACC
ACACCATTTCAAGTTAGAAATTGTACCGATTCATTATATTCATTCAGACAAACCTACAAATACACCTAAGCAAGCTCAAA
AATCCTCTCGTTTAACTGTAGAGATTATGAAGATGCTTGTAATTCAAACGATCTGTGTCTTGCTCGGTATATGGGTTTAC
AACTTAGATAAAAGCGAATCCAGTGCCATTATCTTGCTGATGTTCTTTATCGGTATTATCGTGCTTTCTATTTGGACCCA
ATCCTATTTAATCGGATTCTTTGCGTCTATCTTAAATGTGTTTGTTTTTAATTATTTCTTTACGGTGCCAAGATTCACTT
TAGAAATGTATCGCTTTGAATATCCGATTACGTTTGCGACCAGTATTTTTGCTAGTATCTTTACGAGTGCCATCTTAAAG
AATTTAAAACATCAGCATTCCTTAACAGAACGGCAGTTATATCGGACCAATATTATGCTGCAATTTAACCAGTCCATTAA
AGAATCTTATTCAATTGAACGCTTATTAAATATTGCTGGTGATCAGATTCATCAGCTACTCAATCAGGATGTCACGGTAT
TCTTAATTCAAAGTAAGAAAGTCGCTGCTTCCAACTCATTTGGAAACAGAAGCATTTCAAGCTCAGATAAGACACATGAT
GCTGAGACATTGAGCTGGGTCATTGAAAATGAAAGCCGTGCCGGTAAATTAACCGATACCTTTCCTGGCAGTAAATTTTT
GTGTATTCCCATTGGCACAAATCCAGTCAAAGGTGTGATTTCTATCCGCTTCACCGACGAAACTTACATCGACACCTATG
ACAATTCAATATTAGACTCTATGTTGAACGATATTACCCTGGCAATAGAGAATGTGGATCTATTAAAACAAACCAGACAA
TCCATATTGAAAGCTGAACGAGAAGCCACACGTTCAAACTTCTTGCATTCAATTTCACATGATATTAGAACACCACTGAC
TTCCATTATGGGCAACTTAGATATGCTGAAATACCATAACGAGCATTTAAACGATCAACAACAAGCAGAACTCTTAACTG
CTTCTTATGGCGAAGCACAATATCTGCATACCTTAGTCACAAATATTTTATCTTTGACTAAGTTAGAAAGCTCTGACATT
CAAATACAACGCACCCCTTATTTAGTAGAAGAACTTCTAGAAGAATTTGAAGAAGGCCTCATACGCAGACACCAAGCAAA
TCATGTCATTATTGAAAATGAGGATGACGCTTCACTCATTAATATCGACAGTAAATTAATACTGCAAGTGCTATTCAACC
TTATCGATAATGCTTTAAAGCATGCAGAATCACATTCTGAAATAAAACTGCACGTTCAACATGAAACAAACAAAATAAAA
TTCGAAATGATAGATTGCGGAAAAGGTATTCCAGAAGAAGAACGTCAATTGATTTTTAATCCCTATTATTCAGGAGACAA
CTTTAAAGACAATAAAAAAGATAGTTTGGGATTAGGGCTCTATTTAGTACAACTCATCTTGAAACAACACAACAGTGAAT
TAGAATATCAACCGAATACACCACAAGGCAGTATTTTTTATTTTTATTTGACTGTTAATCCAATTGAAATGGAGGGAGCC
ATGGATGAAAACAACATTATTGGTCGTTGA

Upstream 100 bases:

>100_bases
GGAAAGTTATAAAGAAACTATAAAGATGATTAACAAAACAGAAAGATAAATGGATAATATGTTGTATATTAATTATGATG
TGATTAAGAGGGGGTGCCTC

Downstream 100 bases:

>100_bases
AGATGATGAAGCGATTTTACATTTAATCGATGTTGCGCTAACTATGAATTATTATAAAGTGGTTACGGCGAAGACGGGGA
AAGAAGCGGACTTTCGCCTA

Product: osmosensitive K+ channel signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 889; Mature: 889

Protein sequence:

>889_residues
MESTYKKRGKLTIYLGYSPGVGKTYEMLSNGIDQYQEGADIKIGYIEPHQRPETNALVQQLPEISTSSRKFGSHTFHYID
VSKIIEANPDVVLIDELAHTNISKERHLKRYKDIEEILSHGIDVWTTLNIQHIESLSGQIALMTGIQVTERVPDQFITSA
DAFEVVDISPNMLIQRLKAGKVYKKERLETAFSNFFTYENLTELRELTLRTVADIMSQKGQQYKTKHTDITPHIAVAISG
SIYNERVIREARRAAYKEHAKFTAVYIDVFETPSESRKQDHYVHKNLMLAKALGAEIKVLYAQDIAKALTDWCDLAFVTK
LVLGQSEQPRWKDYFKQSLIEQINHVPHHFKLEIVPIHYIHSDKPTNTPKQAQKSSRLTVEIMKMLVIQTICVLLGIWVY
NLDKSESSAIILLMFFIGIIVLSIWTQSYLIGFFASILNVFVFNYFFTVPRFTLEMYRFEYPITFATSIFASIFTSAILK
NLKHQHSLTERQLYRTNIMLQFNQSIKESYSIERLLNIAGDQIHQLLNQDVTVFLIQSKKVAASNSFGNRSISSSDKTHD
AETLSWVIENESRAGKLTDTFPGSKFLCIPIGTNPVKGVISIRFTDETYIDTYDNSILDSMLNDITLAIENVDLLKQTRQ
SILKAEREATRSNFLHSISHDIRTPLTSIMGNLDMLKYHNEHLNDQQQAELLTASYGEAQYLHTLVTNILSLTKLESSDI
QIQRTPYLVEELLEEFEEGLIRRHQANHVIIENEDDASLINIDSKLILQVLFNLIDNALKHAESHSEIKLHVQHETNKIK
FEMIDCGKGIPEEERQLIFNPYYSGDNFKDNKKDSLGLGLYLVQLILKQHNSELEYQPNTPQGSIFYFYLTVNPIEMEGA
MDENNIIGR

Sequences:

>Translated_889_residues
MESTYKKRGKLTIYLGYSPGVGKTYEMLSNGIDQYQEGADIKIGYIEPHQRPETNALVQQLPEISTSSRKFGSHTFHYID
VSKIIEANPDVVLIDELAHTNISKERHLKRYKDIEEILSHGIDVWTTLNIQHIESLSGQIALMTGIQVTERVPDQFITSA
DAFEVVDISPNMLIQRLKAGKVYKKERLETAFSNFFTYENLTELRELTLRTVADIMSQKGQQYKTKHTDITPHIAVAISG
SIYNERVIREARRAAYKEHAKFTAVYIDVFETPSESRKQDHYVHKNLMLAKALGAEIKVLYAQDIAKALTDWCDLAFVTK
LVLGQSEQPRWKDYFKQSLIEQINHVPHHFKLEIVPIHYIHSDKPTNTPKQAQKSSRLTVEIMKMLVIQTICVLLGIWVY
NLDKSESSAIILLMFFIGIIVLSIWTQSYLIGFFASILNVFVFNYFFTVPRFTLEMYRFEYPITFATSIFASIFTSAILK
NLKHQHSLTERQLYRTNIMLQFNQSIKESYSIERLLNIAGDQIHQLLNQDVTVFLIQSKKVAASNSFGNRSISSSDKTHD
AETLSWVIENESRAGKLTDTFPGSKFLCIPIGTNPVKGVISIRFTDETYIDTYDNSILDSMLNDITLAIENVDLLKQTRQ
SILKAEREATRSNFLHSISHDIRTPLTSIMGNLDMLKYHNEHLNDQQQAELLTASYGEAQYLHTLVTNILSLTKLESSDI
QIQRTPYLVEELLEEFEEGLIRRHQANHVIIENEDDASLINIDSKLILQVLFNLIDNALKHAESHSEIKLHVQHETNKIK
FEMIDCGKGIPEEERQLIFNPYYSGDNFKDNKKDSLGLGLYLVQLILKQHNSELEYQPNTPQGSIFYFYLTVNPIEMEGA
MDENNIIGR
>Mature_889_residues
MESTYKKRGKLTIYLGYSPGVGKTYEMLSNGIDQYQEGADIKIGYIEPHQRPETNALVQQLPEISTSSRKFGSHTFHYID
VSKIIEANPDVVLIDELAHTNISKERHLKRYKDIEEILSHGIDVWTTLNIQHIESLSGQIALMTGIQVTERVPDQFITSA
DAFEVVDISPNMLIQRLKAGKVYKKERLETAFSNFFTYENLTELRELTLRTVADIMSQKGQQYKTKHTDITPHIAVAISG
SIYNERVIREARRAAYKEHAKFTAVYIDVFETPSESRKQDHYVHKNLMLAKALGAEIKVLYAQDIAKALTDWCDLAFVTK
LVLGQSEQPRWKDYFKQSLIEQINHVPHHFKLEIVPIHYIHSDKPTNTPKQAQKSSRLTVEIMKMLVIQTICVLLGIWVY
NLDKSESSAIILLMFFIGIIVLSIWTQSYLIGFFASILNVFVFNYFFTVPRFTLEMYRFEYPITFATSIFASIFTSAILK
NLKHQHSLTERQLYRTNIMLQFNQSIKESYSIERLLNIAGDQIHQLLNQDVTVFLIQSKKVAASNSFGNRSISSSDKTHD
AETLSWVIENESRAGKLTDTFPGSKFLCIPIGTNPVKGVISIRFTDETYIDTYDNSILDSMLNDITLAIENVDLLKQTRQ
SILKAEREATRSNFLHSISHDIRTPLTSIMGNLDMLKYHNEHLNDQQQAELLTASYGEAQYLHTLVTNILSLTKLESSDI
QIQRTPYLVEELLEEFEEGLIRRHQANHVIIENEDDASLINIDSKLILQVLFNLIDNALKHAESHSEIKLHVQHETNKIK
FEMIDCGKGIPEEERQLIFNPYYSGDNFKDNKKDSLGLGLYLVQLILKQHNSELEYQPNTPQGSIFYFYLTVNPIEMEGA
MDENNIIGR

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon. KdpD may function as a membrane-associated protein kinase that phosphorylates kdpE in response to environmental signals [H]

COG id: COG2205

COG function: function code T; Osmosensitive K+ channel histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786912, Length=886, Percent_Identity=26.5237020316027, Blast_Score=342, Evalue=9e-95,
Organism=Escherichia coli, GI1788713, Length=269, Percent_Identity=28.2527881040892, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI145693157, Length=239, Percent_Identity=26.3598326359833, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1788549, Length=240, Percent_Identity=26.25, Blast_Score=87, Evalue=6e-18,
Organism=Escherichia coli, GI1790436, Length=238, Percent_Identity=28.5714285714286, Blast_Score=81, Evalue=3e-16,
Organism=Escherichia coli, GI1786600, Length=223, Percent_Identity=24.2152466367713, Blast_Score=76, Evalue=9e-15,
Organism=Escherichia coli, GI1789149, Length=273, Percent_Identity=24.9084249084249, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI48994928, Length=258, Percent_Identity=25.1937984496124, Blast_Score=73, Evalue=6e-14,
Organism=Escherichia coli, GI1790346, Length=217, Percent_Identity=22.5806451612903, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI87081816, Length=244, Percent_Identity=26.6393442622951, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1788393, Length=216, Percent_Identity=21.2962962962963, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI87082128, Length=226, Percent_Identity=23.8938053097345, Blast_Score=68, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR014729
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR003852
- InterPro:   IPR006016 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF02702 KdpD; PF00582 Usp [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 102018; Mature: 102018

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESTYKKRGKLTIYLGYSPGVGKTYEMLSNGIDQYQEGADIKIGYIEPHQRPETNALVQQ
CCCCHHHCCCEEEEEECCCCCCHHHHHHHCCHHHHHCCCCEEEEEECCCCCCCHHHHHHH
LPEISTSSRKFGSHTFHYIDVSKIIEANPDVVLIDELAHTNISKERHLKRYKDIEEILSH
CCCCCCCCCCCCCCEEEEEEHHHHHCCCCCEEEEECHHCCCCCHHHHHHHHHHHHHHHHC
GIDVWTTLNIQHIESLSGQIALMTGIQVTERVPDQFITSADAFEVVDISPNMLIQRLKAG
CCCEEEECCHHHHHHCCCCEEEEECCHHHHHCCHHHHCCCCCEEEEECCHHHHHHHHHHC
KVYKKERLETAFSNFFTYENLTELRELTLRTVADIMSQKGQQYKTKHTDITPHIAVAISG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCEEEEEEEC
SIYNERVIREARRAAYKEHAKFTAVYIDVFETPSESRKQDHYVHKNLMLAKALGAEIKVL
CHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCEEEE
YAQDIAKALTDWCDLAFVTKLVLGQSEQPRWKDYFKQSLIEQINHVPHHFKLEIVPIHYI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEE
HSDKPTNTPKQAQKSSRLTVEIMKMLVIQTICVLLGIWVYNLDKSESSAIILLMFFIGII
ECCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
VLSIWTQSYLIGFFASILNVFVFNYFFTVPRFTLEMYRFEYPITFATSIFASIFTSAILK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
NLKHQHSLTERQLYRTNIMLQFNQSIKESYSIERLLNIAGDQIHQLLNQDVTVFLIQSKK
HHHHHHHHHHHHHHHHHEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCC
VAASNSFGNRSISSSDKTHDAETLSWVIENESRAGKLTDTFPGSKFLCIPIGTNPVKGVI
EECCCCCCCCCCCCCCCCCCHHHHHEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCEEE
SIRFTDETYIDTYDNSILDSMLNDITLAIENVDLLKQTRQSILKAEREATRSNFLHSISH
EEEECCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DIRTPLTSIMGNLDMLKYHNEHLNDQQQAELLTASYGEAQYLHTLVTNILSLTKLESSDI
HHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCE
QIQRTPYLVEELLEEFEEGLIRRHQANHVIIENEDDASLINIDSKLILQVLFNLIDNALK
EEECCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEECCHHHHHHHHHHHHHHHHH
HAESHSEIKLHVQHETNKIKFEMIDCGKGIPEEERQLIFNPYYSGDNFKDNKKDSLGLGL
HCCCCCEEEEEEEECCCEEEEEEEECCCCCCCHHHHEEECCCCCCCCCCCCCCCCCHHHH
YLVQLILKQHNSELEYQPNTPQGSIFYFYLTVNPIEMEGAMDENNIIGR
HHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECEEEECCCCCCCCCCCC
>Mature Secondary Structure
MESTYKKRGKLTIYLGYSPGVGKTYEMLSNGIDQYQEGADIKIGYIEPHQRPETNALVQQ
CCCCHHHCCCEEEEEECCCCCCHHHHHHHCCHHHHHCCCCEEEEEECCCCCCCHHHHHHH
LPEISTSSRKFGSHTFHYIDVSKIIEANPDVVLIDELAHTNISKERHLKRYKDIEEILSH
CCCCCCCCCCCCCCEEEEEEHHHHHCCCCCEEEEECHHCCCCCHHHHHHHHHHHHHHHHC
GIDVWTTLNIQHIESLSGQIALMTGIQVTERVPDQFITSADAFEVVDISPNMLIQRLKAG
CCCEEEECCHHHHHHCCCCEEEEECCHHHHHCCHHHHCCCCCEEEEECCHHHHHHHHHHC
KVYKKERLETAFSNFFTYENLTELRELTLRTVADIMSQKGQQYKTKHTDITPHIAVAISG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCEEEEEEEC
SIYNERVIREARRAAYKEHAKFTAVYIDVFETPSESRKQDHYVHKNLMLAKALGAEIKVL
CHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCEEEE
YAQDIAKALTDWCDLAFVTKLVLGQSEQPRWKDYFKQSLIEQINHVPHHFKLEIVPIHYI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEE
HSDKPTNTPKQAQKSSRLTVEIMKMLVIQTICVLLGIWVYNLDKSESSAIILLMFFIGII
ECCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
VLSIWTQSYLIGFFASILNVFVFNYFFTVPRFTLEMYRFEYPITFATSIFASIFTSAILK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
NLKHQHSLTERQLYRTNIMLQFNQSIKESYSIERLLNIAGDQIHQLLNQDVTVFLIQSKK
HHHHHHHHHHHHHHHHHEEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCC
VAASNSFGNRSISSSDKTHDAETLSWVIENESRAGKLTDTFPGSKFLCIPIGTNPVKGVI
EECCCCCCCCCCCCCCCCCCHHHHHEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCEEE
SIRFTDETYIDTYDNSILDSMLNDITLAIENVDLLKQTRQSILKAEREATRSNFLHSISH
EEEECCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DIRTPLTSIMGNLDMLKYHNEHLNDQQQAELLTASYGEAQYLHTLVTNILSLTKLESSDI
HHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCE
QIQRTPYLVEELLEEFEEGLIRRHQANHVIIENEDDASLINIDSKLILQVLFNLIDNALK
EEECCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEECCHHHHHHHHHHHHHHHHH
HAESHSEIKLHVQHETNKIKFEMIDCGKGIPEEERQLIFNPYYSGDNFKDNKKDSLGLGL
HCCCCCEEEEEEEECCCEEEEEEEECCCCCCCHHHHEEECCCCCCCCCCCCCCCCCHHHH
YLVQLILKQHNSELEYQPNTPQGSIFYFYLTVNPIEMEGAMDENNIIGR
HHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9226259; 11466286 [H]