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The map label for this gene is rpoC

Identifier: 148260944

GI number: 148260944

Start: 2135587

End: 2139753

Strand: Reverse

Name: rpoC

Synonym: Acry_1951

Alternate gene names: 148260944

Gene position: 2139753-2135587 (Counterclockwise)

Preceding gene: 148260945

Following gene: 148260943

Centisome position: 63.13

GC content: 66.28

Gene sequence:

>4167_bases
ATGAACGATTTGATGAAGATTCTCGGCCAGACCGGTCAGGCCGCCACGTTCGACCAGATCCGTATCCAGATCGCCTCGCC
GGAGCAGATCCGCTCCTGGTCGTATGGCGAGATCAAGAAGCCCGAGACCATCAACTACCGCACCTTCAAGCCCGAGCGCG
ACGGCCTGTTCTGTGCGCGCATCTTCGGGCCGATCAAGGACTACGAGTGCCTCTGCGGCAAGTACAAGCGGATGAAGTTC
CGCGGCATCATCTGCGAGAAATGCGGCGTCGAGGTCACGCTGGCCAAGGTGCGCCGCGAGCGCATGGGCCATATCGAGCT
CGCCTCGCCGGTCGCGCATATCTGGTTCCTGAAGTCGCTGCCGAGCCGCATCGCGACGATGGTCGAGATGACGCTGAAGG
ATCTCGAGAAGGTTCTCTATTTCGAGAACTACATCGTGCTCGACCCCTACACGACCGACCTCAAGCGCTACCAGCTCCTC
TCCGAGGACGATCTCTACGCGAAGCAGGACGAGTTCGGCGAGGACGGGTTCAAGGCCGGCATCGGCGCCGAGGCGGTCAA
ATCGATCCTTGCCGGCATCGATCTCGAGGCCGAGCGGGCGATCATGCGTGCCGACCTGAAGGAGGCGACCTCCGAGGCAA
AGCGCAAGAAGCTGGTCAAGCGCCTAAAGCTGGTCGAGGCCTTCATCGAATCCGGCACCCGTCCGGAATGGATGATCATG
GATGTCGTCCCGGTCATTCCGCCCGAACTGCGCCCGCTCGTCCCGCTCGATGGCGGTCGTTTCGCGACGTCGGACCTGAA
CGATCTCTATCGCCGCGTCATCAACCGCAACAACCGCCTCAAGCGCCTGATCGAGCTGCGCGCGCCGGACATCATCGTGC
GCAACGAGAAGCGCATGCTCCAGGAATCGGTCGACGCGCTGTTCGATAACGGCCGCCGCGGCCGCGCGATCACCGGCACC
AACAAGCGCCCCCTCAAGTCGCTGTCGGACATGCTGAAGGGCAAGCAGGGCCGCTTCCGCCAGAACCTGCTCGGCAAGCG
CGTCGACTATTCGGGCCGTTCGGTCATCGTCGTCGGGCCGGAGCTGAAGCTGCACCAGTGCGGCCTGCCGAAGAAGATGG
CGCTGGAGCTGTTCAAGCCCTTCATCTACGCCAAGCTCGAGAAATACGGCCTCGCCACCACGATCAAGGCGGCGAAGCGC
ATGGTCGAGAAGGAACGTCCCGAGGTGTGGGACATTCTCGAGGAGGTGATCCGCGAGCATCCGGTGCTGCTCAACCGCGC
GCCGACGCTGCACCGTCTCGGCATCCAGGCCTTCGAGCCGATCCTGATCGAGGGCAAGGCGATCCAGCTGCACCCGCTGG
TCTGCACCGCCTTCAACGCCGACTTCGACGGCGACCAGATGGCGGTCCACGTGCCGCTCTCGATCGAGGCGCAGCTCGAG
GCCCGCGTGCTGATGATGAGCACGAACAACATCCTCAACCCGGCCAACGGCAAGCCGATCATCGTGCCGAGCCAGGACAT
CGTGCTCGGCCTCTATTACCTCTCGCTCGAAACTCCGGCCTTCACCGGTGTCGAGGACAAGGAAGCGCCGCTCTTCGGCA
CGATGGGCGAGATCGAGCACGCGCTCGATTCCGGCTATCTGAAGCTGCACGACAAGATCCGCGCCCGCGTCGTCCGCACC
CATCCGGACGGCAGCCGCACCACCGAAGTGGTCCCGACCACGCCGGGCCGCATGATGATCGGCCAGCTTCTGCCCAAGCA
TCACGACGTGCCGTTCGCCCTGGTCAACCAGCTGCTGACCAAGAAGAAGGTGTCGGACGTGATCGACGCCGTCTACCGTC
ATTGCGGCCAGAAGGAGTCGGTGATCTTCTGCGACCGGCTGATGGGCCTCGGCTTCCGCCAGGCGGCCAAGGCCGGCATT
TCCTTCGGCAAGGACGACATGGTCATCCCGGCCGAGAAATACGGCCTGCTGGAAAAGACCCAGGCCGAGGTCAAGGAATA
CGAGGCGCAGTATCACGACGGTCTCATCACCGCCGGCGAGCGCTACAACAAGGTGATCGACGCCTGGTCGCGCTGTAACG
ACGAGGTCGCGGCCGCGATGATGCGCGAGATCTCGCGCCAGGATCCCGGCAAGCCGACCAACTCGGTCTGGATGATGAGC
CATTCCGGCGCCCGCGGGTCGCCGACCCAGATGCGCCAGCTCGCCGGCATGCGCGGCCTGATGGCCAAGCCGTCGGGCGA
GATCATCGAGCAGCCGATCCTGTCGAACTTCAAGGAAGGCCTGACCGTCGCCGAATACTTCAACTCGACCCACGGCGCCC
GCAAGGGCCTCGCGGACACCGCGCTGAAGACGGCGAACTCCGGCTACCTCACCCGCCGCCTGGTCGACGTGGCGCAGGAC
TGCATCATCGTCACCGCCGATTGCGGCACCGAGCGCGGCCTGACCATGCGCGCGGTGATGGATGGCGGCGAGGTGGTCTC
CTCGCTCTCCGAGCGCATCCTCGGCCGCACCGCGGCGGAAGACGTGCTCGACCCGGCCGACGGTTCGGTGATCGTCAAGG
CGAACGAGCTGATCGGCGAGATCGACTCGATGCATATCGAGAAGCTCGGGGTCGAGAGCGTGAAGATCCGCTCGGTGCTG
ACCTGCGAGGCCAAGGTCGGCGTCTGCGCCAAGTGCTACGGGCGCGACCTCGCGCGCGGCACGCCGGTCAATATCGGCGA
GGCCGTGGGCGTCATCGCCGCGCAGTCGATCGGCGAGCCGGGCACCCAGCTGACCATGCGCACCTTCCATATCGGCGGTG
CCGCGCAGCGTGGCGCCGAGCAGTCGAGCGTCGAGGCCAGCCATGACGGCACGGTGACCATCCGCAACCGCAACGTGGTG
TCGAACTCGGCCGGCGCGCCGATCGTCATGAGCCGCAACTGCGAGATCGCGCTGAACGACGCCTCCGGCCGCGAGCGCGC
CCGCTTCCGCGTTCCCTACGGCGCCCGCCTGCTGGTGGACGAGGACCAGACGGTCACGCGCGGCCAGAAGCTCGCGGAGT
GGGATCCCTACACCCTGCCGATCATCACCGAGCGCGCCGGCCTCGTGGAATACGCCGACCTGCTGGAAGGCGTGACCCTG
GTCGAGCGGGTCGACGAGGTGACCGGCCTGACCTCCAAGGTGGTGGTGGACTACAAGCAGTCGGCCAAGGGGGCGGATCT
GCGTCCGCGCCTGATCCTGAAGGACGAACGCGGCGAGGTGCTGCGCCTCGCCAACGGCGCCGAGGCCCGCTACTTCCTCA
GCCCCGACTCGATCCTCTCGGTCGAGAACGGTGCCAGCGTGCATGCCGGCGACGTGCTCGCCCGCATCCCGCGTGAGGGC
AGCAAGACGCGCGACATCACCGGCGGTCTGCCGCGCGTGGCCGAACTGTTCGAGGCCCGCCGTCCGAAGGATCACGCGAT
CATCGCGGAAACCGACGGCCGCGTGGAATTCGGCAAGGACTACAAGGCGAAGCGCCGCATCATCGTGAAGAACGACGAGA
CCGGCGAGGAAACCGAGTATCTGGTGCCGAAGGGCAAGCACGTCTCGGTGCAGGAGGGCGACTACGTCCACCGCGGCGAC
CCGCTGGTCGACGGCCCGCGCGTCCCGCACGACATCCTGCGCGTGCTCGGCGTCGAGGCGCTGTCCGAATATCTCATCAA
CGAGATCCAGGACGTCTACCGGCTCCAGGGCGTGAAGATCAACGACAAGCACATCGAGGTGGTCGTCCGCCAGATGCTGC
AGAAGATCGAGATCACCGAGCCCGGCGACACCACCTACCTGGTCGGCGAGCTGGTCGACCGGATCGAGTTCGACGAGGAG
AACGAGCGCCGGCTGCGCGCGGGCGAACGCCCGGCGGGTGGCCTGCCGGTGCTGCAGGGCATCACCAAGGCGAGCCTGCA
GACGCTCAGCTTCATCTCGGCGGCCTCCTTCCAGGAGACCACCCGCGTCCTCACCGAGGCGGCGACGGCCGGCAAGACCG
ACCAGCTGCTCGGCCTCAAGGAGAACGTGATCGTCGGCCGCCTGATCCCGGCCGGCACCGGCAGCGTGATGAGCCGTCTG
CGCTCCATCGCCGCCGGCCGCGACCGCTCGACCCTCGCGGCGACTCGCCCGGCCCTGCCGGCGCGCGACGAGGTCTCGGC
GGACTAA

Upstream 100 bases:

>100_bases
AACGTCGATCTCAACCTGTCCGTGGACTGACCAGGACCGTTCGGATTTGTCATGGCGCGGGGCGGCGACCCCGTCCCGCG
CTGATGAAAGGGACTATCGC

Downstream 100 bases:

>100_bases
TCTCCGCCCCGACCGGGCTTCGATCGGAACGGCTCCCGGGCAACCGGGAGCCGTTTTTTCGTTCTCGCCCGGCGGGAGCG
GGCTTTTCCTCCGCTCATGG

Product: DNA-directed RNA polymerase subunit beta'

Products: NA

Alternate protein names: RNAP subunit beta'; RNA polymerase subunit beta'; Transcriptase subunit beta'

Number of amino acids: Translated: 1388; Mature: 1388

Protein sequence:

>1388_residues
MNDLMKILGQTGQAATFDQIRIQIASPEQIRSWSYGEIKKPETINYRTFKPERDGLFCARIFGPIKDYECLCGKYKRMKF
RGIICEKCGVEVTLAKVRRERMGHIELASPVAHIWFLKSLPSRIATMVEMTLKDLEKVLYFENYIVLDPYTTDLKRYQLL
SEDDLYAKQDEFGEDGFKAGIGAEAVKSILAGIDLEAERAIMRADLKEATSEAKRKKLVKRLKLVEAFIESGTRPEWMIM
DVVPVIPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLIELRAPDIIVRNEKRMLQESVDALFDNGRRGRAITGT
NKRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPELKLHQCGLPKKMALELFKPFIYAKLEKYGLATTIKAAKR
MVEKERPEVWDILEEVIREHPVLLNRAPTLHRLGIQAFEPILIEGKAIQLHPLVCTAFNADFDGDQMAVHVPLSIEAQLE
ARVLMMSTNNILNPANGKPIIVPSQDIVLGLYYLSLETPAFTGVEDKEAPLFGTMGEIEHALDSGYLKLHDKIRARVVRT
HPDGSRTTEVVPTTPGRMMIGQLLPKHHDVPFALVNQLLTKKKVSDVIDAVYRHCGQKESVIFCDRLMGLGFRQAAKAGI
SFGKDDMVIPAEKYGLLEKTQAEVKEYEAQYHDGLITAGERYNKVIDAWSRCNDEVAAAMMREISRQDPGKPTNSVWMMS
HSGARGSPTQMRQLAGMRGLMAKPSGEIIEQPILSNFKEGLTVAEYFNSTHGARKGLADTALKTANSGYLTRRLVDVAQD
CIIVTADCGTERGLTMRAVMDGGEVVSSLSERILGRTAAEDVLDPADGSVIVKANELIGEIDSMHIEKLGVESVKIRSVL
TCEAKVGVCAKCYGRDLARGTPVNIGEAVGVIAAQSIGEPGTQLTMRTFHIGGAAQRGAEQSSVEASHDGTVTIRNRNVV
SNSAGAPIVMSRNCEIALNDASGRERARFRVPYGARLLVDEDQTVTRGQKLAEWDPYTLPIITERAGLVEYADLLEGVTL
VERVDEVTGLTSKVVVDYKQSAKGADLRPRLILKDERGEVLRLANGAEARYFLSPDSILSVENGASVHAGDVLARIPREG
SKTRDITGGLPRVAELFEARRPKDHAIIAETDGRVEFGKDYKAKRRIIVKNDETGEETEYLVPKGKHVSVQEGDYVHRGD
PLVDGPRVPHDILRVLGVEALSEYLINEIQDVYRLQGVKINDKHIEVVVRQMLQKIEITEPGDTTYLVGELVDRIEFDEE
NERRLRAGERPAGGLPVLQGITKASLQTLSFISAASFQETTRVLTEAATAGKTDQLLGLKENVIVGRLIPAGTGSVMSRL
RSIAAGRDRSTLAATRPALPARDEVSAD

Sequences:

>Translated_1388_residues
MNDLMKILGQTGQAATFDQIRIQIASPEQIRSWSYGEIKKPETINYRTFKPERDGLFCARIFGPIKDYECLCGKYKRMKF
RGIICEKCGVEVTLAKVRRERMGHIELASPVAHIWFLKSLPSRIATMVEMTLKDLEKVLYFENYIVLDPYTTDLKRYQLL
SEDDLYAKQDEFGEDGFKAGIGAEAVKSILAGIDLEAERAIMRADLKEATSEAKRKKLVKRLKLVEAFIESGTRPEWMIM
DVVPVIPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLIELRAPDIIVRNEKRMLQESVDALFDNGRRGRAITGT
NKRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPELKLHQCGLPKKMALELFKPFIYAKLEKYGLATTIKAAKR
MVEKERPEVWDILEEVIREHPVLLNRAPTLHRLGIQAFEPILIEGKAIQLHPLVCTAFNADFDGDQMAVHVPLSIEAQLE
ARVLMMSTNNILNPANGKPIIVPSQDIVLGLYYLSLETPAFTGVEDKEAPLFGTMGEIEHALDSGYLKLHDKIRARVVRT
HPDGSRTTEVVPTTPGRMMIGQLLPKHHDVPFALVNQLLTKKKVSDVIDAVYRHCGQKESVIFCDRLMGLGFRQAAKAGI
SFGKDDMVIPAEKYGLLEKTQAEVKEYEAQYHDGLITAGERYNKVIDAWSRCNDEVAAAMMREISRQDPGKPTNSVWMMS
HSGARGSPTQMRQLAGMRGLMAKPSGEIIEQPILSNFKEGLTVAEYFNSTHGARKGLADTALKTANSGYLTRRLVDVAQD
CIIVTADCGTERGLTMRAVMDGGEVVSSLSERILGRTAAEDVLDPADGSVIVKANELIGEIDSMHIEKLGVESVKIRSVL
TCEAKVGVCAKCYGRDLARGTPVNIGEAVGVIAAQSIGEPGTQLTMRTFHIGGAAQRGAEQSSVEASHDGTVTIRNRNVV
SNSAGAPIVMSRNCEIALNDASGRERARFRVPYGARLLVDEDQTVTRGQKLAEWDPYTLPIITERAGLVEYADLLEGVTL
VERVDEVTGLTSKVVVDYKQSAKGADLRPRLILKDERGEVLRLANGAEARYFLSPDSILSVENGASVHAGDVLARIPREG
SKTRDITGGLPRVAELFEARRPKDHAIIAETDGRVEFGKDYKAKRRIIVKNDETGEETEYLVPKGKHVSVQEGDYVHRGD
PLVDGPRVPHDILRVLGVEALSEYLINEIQDVYRLQGVKINDKHIEVVVRQMLQKIEITEPGDTTYLVGELVDRIEFDEE
NERRLRAGERPAGGLPVLQGITKASLQTLSFISAASFQETTRVLTEAATAGKTDQLLGLKENVIVGRLIPAGTGSVMSRL
RSIAAGRDRSTLAATRPALPARDEVSAD
>Mature_1388_residues
MNDLMKILGQTGQAATFDQIRIQIASPEQIRSWSYGEIKKPETINYRTFKPERDGLFCARIFGPIKDYECLCGKYKRMKF
RGIICEKCGVEVTLAKVRRERMGHIELASPVAHIWFLKSLPSRIATMVEMTLKDLEKVLYFENYIVLDPYTTDLKRYQLL
SEDDLYAKQDEFGEDGFKAGIGAEAVKSILAGIDLEAERAIMRADLKEATSEAKRKKLVKRLKLVEAFIESGTRPEWMIM
DVVPVIPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLIELRAPDIIVRNEKRMLQESVDALFDNGRRGRAITGT
NKRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPELKLHQCGLPKKMALELFKPFIYAKLEKYGLATTIKAAKR
MVEKERPEVWDILEEVIREHPVLLNRAPTLHRLGIQAFEPILIEGKAIQLHPLVCTAFNADFDGDQMAVHVPLSIEAQLE
ARVLMMSTNNILNPANGKPIIVPSQDIVLGLYYLSLETPAFTGVEDKEAPLFGTMGEIEHALDSGYLKLHDKIRARVVRT
HPDGSRTTEVVPTTPGRMMIGQLLPKHHDVPFALVNQLLTKKKVSDVIDAVYRHCGQKESVIFCDRLMGLGFRQAAKAGI
SFGKDDMVIPAEKYGLLEKTQAEVKEYEAQYHDGLITAGERYNKVIDAWSRCNDEVAAAMMREISRQDPGKPTNSVWMMS
HSGARGSPTQMRQLAGMRGLMAKPSGEIIEQPILSNFKEGLTVAEYFNSTHGARKGLADTALKTANSGYLTRRLVDVAQD
CIIVTADCGTERGLTMRAVMDGGEVVSSLSERILGRTAAEDVLDPADGSVIVKANELIGEIDSMHIEKLGVESVKIRSVL
TCEAKVGVCAKCYGRDLARGTPVNIGEAVGVIAAQSIGEPGTQLTMRTFHIGGAAQRGAEQSSVEASHDGTVTIRNRNVV
SNSAGAPIVMSRNCEIALNDASGRERARFRVPYGARLLVDEDQTVTRGQKLAEWDPYTLPIITERAGLVEYADLLEGVTL
VERVDEVTGLTSKVVVDYKQSAKGADLRPRLILKDERGEVLRLANGAEARYFLSPDSILSVENGASVHAGDVLARIPREG
SKTRDITGGLPRVAELFEARRPKDHAIIAETDGRVEFGKDYKAKRRIIVKNDETGEETEYLVPKGKHVSVQEGDYVHRGD
PLVDGPRVPHDILRVLGVEALSEYLINEIQDVYRLQGVKINDKHIEVVVRQMLQKIEITEPGDTTYLVGELVDRIEFDEE
NERRLRAGERPAGGLPVLQGITKASLQTLSFISAASFQETTRVLTEAATAGKTDQLLGLKENVIVGRLIPAGTGSVMSRL
RSIAAGRDRSTLAATRPALPARDEVSAD

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates

COG id: COG0086

COG function: function code K; DNA-directed RNA polymerase, beta' subunit/160 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta' chain family

Homologues:

Organism=Homo sapiens, GI4505939, Length=942, Percent_Identity=24.5222929936306, Blast_Score=188, Evalue=4e-47,
Organism=Homo sapiens, GI39725938, Length=314, Percent_Identity=30.8917197452229, Blast_Score=126, Evalue=1e-28,
Organism=Homo sapiens, GI103471997, Length=337, Percent_Identity=27.893175074184, Blast_Score=92, Evalue=3e-18,
Organism=Escherichia coli, GI2367335, Length=1400, Percent_Identity=59.7857142857143, Blast_Score=1664, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71987878, Length=941, Percent_Identity=24.442082890542, Blast_Score=186, Evalue=9e-47,
Organism=Caenorhabditis elegans, GI25145495, Length=899, Percent_Identity=24.8053392658509, Blast_Score=177, Evalue=3e-44,
Organism=Saccharomyces cerevisiae, GI6320061, Length=915, Percent_Identity=25.6830601092896, Blast_Score=177, Evalue=1e-44,
Organism=Saccharomyces cerevisiae, GI6324690, Length=669, Percent_Identity=25.7100149476831, Blast_Score=165, Evalue=5e-41,
Organism=Drosophila melanogaster, GI281360912, Length=729, Percent_Identity=26.7489711934156, Blast_Score=168, Evalue=2e-41,
Organism=Drosophila melanogaster, GI17530899, Length=487, Percent_Identity=28.7474332648871, Blast_Score=163, Evalue=8e-40,
Organism=Drosophila melanogaster, GI17647875, Length=380, Percent_Identity=26.8421052631579, Blast_Score=107, Evalue=5e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RPOC_ACICJ (A5FZX0)

Other databases:

- EMBL:   CP000697
- RefSeq:   YP_001235071.1
- ProteinModelPortal:   A5FZX0
- STRING:   A5FZX0
- GeneID:   5160234
- GenomeReviews:   CP000697_GR
- KEGG:   acr:Acry_1951
- eggNOG:   COG0086
- HOGENOM:   HBG621785
- OMA:   FEARVPK
- ProtClustDB:   PRK00566
- BioCyc:   ACRY349163:ACRY_1951-MONOMER
- HAMAP:   MF_01322
- InterPro:   IPR000722
- InterPro:   IPR006592
- InterPro:   IPR007080
- InterPro:   IPR007066
- InterPro:   IPR007083
- InterPro:   IPR007081
- InterPro:   IPR012754
- SMART:   SM00663
- TIGRFAMs:   TIGR02386

Pfam domain/function: PF04997 RNA_pol_Rpb1_1; PF00623 RNA_pol_Rpb1_2; PF04983 RNA_pol_Rpb1_3; PF05000 RNA_pol_Rpb1_4; PF04998 RNA_pol_Rpb1_5

EC number: =2.7.7.6

Molecular weight: Translated: 153792; Mature: 153792

Theoretical pI: Translated: 7.93; Mature: 7.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDLMKILGQTGQAATFDQIRIQIASPEQIRSWSYGEIKKPETINYRTFKPERDGLFCAR
CCHHHHHHCCCCCCCEEEEEEEEECCCHHHCCCCCCCCCCCCCCCEEECCCCCCCEEEEH
IFGPIKDYECLCGKYKRMKFRGIICEKCGVEVTLAKVRRERMGHIELASPVAHIWFLKSL
HHCCCCHHHHHHHHHHHHHHHCCHHHHCCCEEHHHHHHHHHCCCEEHHHHHHHHHHHHHH
PSRIATMVEMTLKDLEKVLYFENYIVLDPYTTDLKRYQLLSEDDLYAKQDEFGEDGFKAG
HHHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHCCCCCCCCCCHHCCCCCHHCC
IGAEAVKSILAGIDLEAERAIMRADLKEATSEAKRKKLVKRLKLVEAFIESGTRPEWMIM
CCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
DVVPVIPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLIELRAPDIIVRNEKRML
EECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCEEEECHHHHH
QESVDALFDNGRRGRAITGTNKRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVVGP
HHHHHHHHCCCCCCCEECCCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEECC
ELKLHQCGLPKKMALELFKPFIYAKLEKYGLATTIKAAKRMVEKERPEVWDILEEVIREH
CCEEHHCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHC
PVLLNRAPTLHRLGIQAFEPILIEGKAIQLHPLVCTAFNADFDGDQMAVHVPLSIEAQLE
CEEECCCCCHHHHCHHHCCCEEEECCEEEEEEEEEEEECCCCCCCCEEEEECEEEEECCC
ARVLMMSTNNILNPANGKPIIVPSQDIVLGLYYLSLETPAFTGVEDKEAPLFGTMGEIEH
EEEEEEECCCCCCCCCCCEEEECCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHH
ALDSGYLKLHDKIRARVVRTHPDGSRTTEVVPTTPGRMMIGQLLPKHHDVPFALVNQLLT
HHCCCHHHHHHHHHHEEEEECCCCCCCCEEECCCCCHHHHHHHCCCCCCCCHHHHHHHHH
KKKVSDVIDAVYRHCGQKESVIFCDRLMGLGFRQAAKAGISFGKDDMVIPAEKYGLLEKT
HHHHHHHHHHHHHHCCCCCCEEHHHHHHCCCHHHHHHHCCCCCCCCEEECHHHHCCHHHH
QAEVKEYEAQYHDGLITAGERYNKVIDAWSRCNDEVAAAMMREISRQDPGKPTNSVWMMS
HHHHHHHHHHHHCCEEECCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCEEEEE
HSGARGSPTQMRQLAGMRGLMAKPSGEIIEQPILSNFKEGLTVAEYFNSTHGARKGLADT
CCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCHHHHHHCCCCHHHCCHHHH
ALKTANSGYLTRRLVDVAQDCIIVTADCGTERGLTMRAVMDGGEVVSSLSERILGRTAAE
HHHHCCCCHHHHHHHHHHCCCEEEEECCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHH
DVLDPADGSVIVKANELIGEIDSMHIEKLGVESVKIRSVLTCEAKVGVCAKCYGRDLARG
HHCCCCCCCEEEEEHHHHHHHHHHHHHHHCCCCEEEHHEEEECCCCCHHHHHHCCHHCCC
TPVNIGEAVGVIAAQSIGEPGTQLTMRTFHIGGAAQRGAEQSSVEASHDGTVTIRNRNVV
CCCCHHHHHHHHHHHHCCCCCCEEEEEEEECCCHHHCCCCHHCCCCCCCCEEEEECCCEE
SNSAGAPIVMSRNCEIALNDASGRERARFRVPYGARLLVDEDQTVTRGQKLAEWDPYTLP
CCCCCCCEEEECCCEEEEECCCCCCCCEEECCCCCEEEEECCCHHHCCCHHCCCCCCEEE
IITERAGLVEYADLLEGVTLVERVDEVTGLTSKVVVDYKQSAKGADLRPRLILKDERGEV
EEECCCCHHHHHHHHHHHHHHHHHHHHHCCHHHEEEEEHHCCCCCCCCCEEEEECCCCCE
LRLANGAEARYFLSPDSILSVENGASVHAGDVLARIPREGSKTRDITGGLPRVAELFEAR
EEECCCCCEEEEECCCCEEEECCCCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHC
RPKDHAIIAETDGRVEFGKDYKAKRRIIVKNDETGEETEYLVPKGKHVSVQEGDYVHRGD
CCCCCEEEEECCCCEECCCCCCCCCEEEEECCCCCCCCCEECCCCCEEEECCCCEEECCC
PLVDGPRVPHDILRVLGVEALSEYLINEIQDVYRLQGVKINDKHIEVVVRQMLQKIEITE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHHHCCCCC
PGDTTYLVGELVDRIEFDEENERRLRAGERPAGGLPVLQGITKASLQTLSFISAASFQET
CCCCEEEHHHHHHHHCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TRVLTEAATAGKTDQLLGLKENVIVGRLIPAGTGSVMSRLRSIAAGRDRSTLAATRPALP
HHHHHHHHHCCCCHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCHHHHCCCCCC
ARDEVSAD
CCCCCCCC
>Mature Secondary Structure
MNDLMKILGQTGQAATFDQIRIQIASPEQIRSWSYGEIKKPETINYRTFKPERDGLFCAR
CCHHHHHHCCCCCCCEEEEEEEEECCCHHHCCCCCCCCCCCCCCCEEECCCCCCCEEEEH
IFGPIKDYECLCGKYKRMKFRGIICEKCGVEVTLAKVRRERMGHIELASPVAHIWFLKSL
HHCCCCHHHHHHHHHHHHHHHCCHHHHCCCEEHHHHHHHHHCCCEEHHHHHHHHHHHHHH
PSRIATMVEMTLKDLEKVLYFENYIVLDPYTTDLKRYQLLSEDDLYAKQDEFGEDGFKAG
HHHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHCCCCCCCCCCHHCCCCCHHCC
IGAEAVKSILAGIDLEAERAIMRADLKEATSEAKRKKLVKRLKLVEAFIESGTRPEWMIM
CCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
DVVPVIPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLIELRAPDIIVRNEKRML
EECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCEEEECHHHHH
QESVDALFDNGRRGRAITGTNKRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVVGP
HHHHHHHHCCCCCCCEECCCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEECC
ELKLHQCGLPKKMALELFKPFIYAKLEKYGLATTIKAAKRMVEKERPEVWDILEEVIREH
CCEEHHCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHC
PVLLNRAPTLHRLGIQAFEPILIEGKAIQLHPLVCTAFNADFDGDQMAVHVPLSIEAQLE
CEEECCCCCHHHHCHHHCCCEEEECCEEEEEEEEEEEECCCCCCCCEEEEECEEEEECCC
ARVLMMSTNNILNPANGKPIIVPSQDIVLGLYYLSLETPAFTGVEDKEAPLFGTMGEIEH
EEEEEEECCCCCCCCCCCEEEECCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHH
ALDSGYLKLHDKIRARVVRTHPDGSRTTEVVPTTPGRMMIGQLLPKHHDVPFALVNQLLT
HHCCCHHHHHHHHHHEEEEECCCCCCCCEEECCCCCHHHHHHHCCCCCCCCHHHHHHHHH
KKKVSDVIDAVYRHCGQKESVIFCDRLMGLGFRQAAKAGISFGKDDMVIPAEKYGLLEKT
HHHHHHHHHHHHHHCCCCCCEEHHHHHHCCCHHHHHHHCCCCCCCCEEECHHHHCCHHHH
QAEVKEYEAQYHDGLITAGERYNKVIDAWSRCNDEVAAAMMREISRQDPGKPTNSVWMMS
HHHHHHHHHHHHCCEEECCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCEEEEE
HSGARGSPTQMRQLAGMRGLMAKPSGEIIEQPILSNFKEGLTVAEYFNSTHGARKGLADT
CCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCHHHHHHCCCCHHHCCHHHH
ALKTANSGYLTRRLVDVAQDCIIVTADCGTERGLTMRAVMDGGEVVSSLSERILGRTAAE
HHHHCCCCHHHHHHHHHHCCCEEEEECCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHH
DVLDPADGSVIVKANELIGEIDSMHIEKLGVESVKIRSVLTCEAKVGVCAKCYGRDLARG
HHCCCCCCCEEEEEHHHHHHHHHHHHHHHCCCCEEEHHEEEECCCCCHHHHHHCCHHCCC
TPVNIGEAVGVIAAQSIGEPGTQLTMRTFHIGGAAQRGAEQSSVEASHDGTVTIRNRNVV
CCCCHHHHHHHHHHHHCCCCCCEEEEEEEECCCHHHCCCCHHCCCCCCCCEEEEECCCEE
SNSAGAPIVMSRNCEIALNDASGRERARFRVPYGARLLVDEDQTVTRGQKLAEWDPYTLP
CCCCCCCEEEECCCEEEEECCCCCCCCEEECCCCCEEEEECCCHHHCCCHHCCCCCCEEE
IITERAGLVEYADLLEGVTLVERVDEVTGLTSKVVVDYKQSAKGADLRPRLILKDERGEV
EEECCCCHHHHHHHHHHHHHHHHHHHHHCCHHHEEEEEHHCCCCCCCCCEEEEECCCCCE
LRLANGAEARYFLSPDSILSVENGASVHAGDVLARIPREGSKTRDITGGLPRVAELFEAR
EEECCCCCEEEEECCCCEEEECCCCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHC
RPKDHAIIAETDGRVEFGKDYKAKRRIIVKNDETGEETEYLVPKGKHVSVQEGDYVHRGD
CCCCCEEEEECCCCEECCCCCCCCCEEEEECCCCCCCCCEECCCCCEEEECCCCEEECCC
PLVDGPRVPHDILRVLGVEALSEYLINEIQDVYRLQGVKINDKHIEVVVRQMLQKIEITE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHHHCCCCC
PGDTTYLVGELVDRIEFDEENERRLRAGERPAGGLPVLQGITKASLQTLSFISAASFQET
CCCCEEEHHHHHHHHCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TRVLTEAATAGKTDQLLGLKENVIVGRLIPAGTGSVMSRLRSIAAGRDRSTLAATRPALP
HHHHHHHHHCCCCHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCHHHHCCCCCC
ARDEVSAD
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA