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The map label for this gene is alsB [H]

Identifier: 148260847

GI number: 148260847

Start: 2044319

End: 2045338

Strand: Reverse

Name: alsB [H]

Synonym: Acry_1853

Alternate gene names: 148260847

Gene position: 2045338-2044319 (Counterclockwise)

Preceding gene: 148260848

Following gene: 148260846

Centisome position: 60.35

GC content: 65.69

Gene sequence:

>1020_bases
ATGAAACTACGCAAGACATTGCTCGGTGCCGCGGCGGTCGCGCTGCTCGGCGGCATGGCGGCGGCGCCGGCCATGGCGGC
CGCGCCCACCGTTCATTCGCTGCCGGTGCCGGCCAAGCCGGCGAAGCATTATCATTTCACGCTCATCACGAAATCCAACG
CCTCGCCCTACTGGCTCGCGGTGCGCGAGGGGGCGGACGCGGCGGCGAAGAAGTTCGGCGTTTCGGTCGCCTTCGAGGCG
CCGGCCAGCGGCACCGACCTCGCCGGGCAGATCGGCATGGTCAATAACGCGGTGACAGGAGGCACTGACGGCATCATCCT
CGCCGCGCAGAATCCGCAGGCGCTGCTCAAGCCGGTGAAGTCGGCACTCGCGCATCACATTCCGGTGGTGACGGTCGATT
CCGGCCTGTCGCCCAACATCTCGGACTGCTTCCTCGCCACCTCGAATGTCGGGGCCGCGGCGGCGCTCGCGAAATATACG
GCCGACCACCTGATGGGCGGCAAGGGACAGTATGCGATCGTCGACTTCAACCACACCGCCTCGACCGGAATCGCCCGGCC
GAAAGGCTTCATGCTCGGGATGAAGTCCTATCCGCACATCAAGAAGATGGGGCCGATCCAGTATTCCAACAACGACGTCA
GCGCCGGGCTGCGGATCGCGACCACGATGCTTACGCAATACCCGCATCTCAAGGTGATCTTCGGCGCGAACGACCGCGCG
GCGCTCGGCCCGGCCGAGGCGGTGCAGCGCGCGCACGCCAAGGTGAAGGTCGTCGGGTTCGATGCCGATCTTGGCGAGAT
CGCGCTGGTCAAGGCGGGGATCATCCAGGCCTCGATCCTGCAATCGCCCTACGACATGGGCTATTACGCGGTGGTCGCGC
TGCTCGACAAGCTCGACGGCAAGACGCTGCCGAAGCGGATCAACACGCCGTATTTCCTGCTGACGCCGAAGAATCTCGGC
TCCAGCCAGGCGACGGCGGCGATCCGCCAGTACGCGCCCAAGTATAACCCCGCGGGCTGA

Upstream 100 bases:

>100_bases
TGTTCGACGCGCGCTCGGCCGAGACGTCGCAGACCGAACTGATCCGCTACATGACCGGCTATGCGGATGCCGAAACCAAC
GAAGCCGAAAGGGAACATCC

Downstream 100 bases:

>100_bases
GGGAGACTGGCGGACGATGGACCAGCAGGCACGAACAGCCGCGCTCGACGTCGAGACCATTCCGCGCGGGCGCATGCTGT
GGCGCTTCGTCCGCCAGATC

Product: periplasmic binding protein/LacI transcriptional regulator

Products: ADP; phosphate; ribose [Cytoplasm]; D-allose [Cytoplasm] [C]

Alternate protein names: ALBP [H]

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MKLRKTLLGAAAVALLGGMAAAPAMAAAPTVHSLPVPAKPAKHYHFTLITKSNASPYWLAVREGADAAAKKFGVSVAFEA
PASGTDLAGQIGMVNNAVTGGTDGIILAAQNPQALLKPVKSALAHHIPVVTVDSGLSPNISDCFLATSNVGAAAALAKYT
ADHLMGGKGQYAIVDFNHTASTGIARPKGFMLGMKSYPHIKKMGPIQYSNNDVSAGLRIATTMLTQYPHLKVIFGANDRA
ALGPAEAVQRAHAKVKVVGFDADLGEIALVKAGIIQASILQSPYDMGYYAVVALLDKLDGKTLPKRINTPYFLLTPKNLG
SSQATAAIRQYAPKYNPAG

Sequences:

>Translated_339_residues
MKLRKTLLGAAAVALLGGMAAAPAMAAAPTVHSLPVPAKPAKHYHFTLITKSNASPYWLAVREGADAAAKKFGVSVAFEA
PASGTDLAGQIGMVNNAVTGGTDGIILAAQNPQALLKPVKSALAHHIPVVTVDSGLSPNISDCFLATSNVGAAAALAKYT
ADHLMGGKGQYAIVDFNHTASTGIARPKGFMLGMKSYPHIKKMGPIQYSNNDVSAGLRIATTMLTQYPHLKVIFGANDRA
ALGPAEAVQRAHAKVKVVGFDADLGEIALVKAGIIQASILQSPYDMGYYAVVALLDKLDGKTLPKRINTPYFLLTPKNLG
SSQATAAIRQYAPKYNPAG
>Mature_339_residues
MKLRKTLLGAAAVALLGGMAAAPAMAAAPTVHSLPVPAKPAKHYHFTLITKSNASPYWLAVREGADAAAKKFGVSVAFEA
PASGTDLAGQIGMVNNAVTGGTDGIILAAQNPQALLKPVKSALAHHIPVVTVDSGLSPNISDCFLATSNVGAAAALAKYT
ADHLMGGKGQYAIVDFNHTASTGIARPKGFMLGMKSYPHIKKMGPIQYSNNDVSAGLRIATTMLTQYPHLKVIFGANDRA
ALGPAEAVQRAHAKVKVVGFDADLGEIALVKAGIIQASILQSPYDMGYYAVVALLDKLDGKTLPKRINTPYFLLTPKNLG
SSQATAAIRQYAPKYNPAG

Specific function: Part of the binding-protein-dependent transport system AlsBAC for D-allose [H]

COG id: COG1879

COG function: function code G; ABC-type sugar transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 2 family [H]

Homologues:

Organism=Escherichia coli, GI1790526, Length=281, Percent_Identity=30.6049822064057, Blast_Score=101, Evalue=8e-23,
Organism=Escherichia coli, GI1790192, Length=262, Percent_Identity=26.7175572519084, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001761 [H]

Pfam domain/function: PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 35251; Mature: 35251

Theoretical pI: Translated: 10.20; Mature: 10.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLRKTLLGAAAVALLGGMAAAPAMAAAPTVHSLPVPAKPAKHYHFTLITKSNASPYWLA
CCHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCCCEEEE
VREGADAAAKKFGVSVAFEAPASGTDLAGQIGMVNNAVTGGTDGIILAAQNPQALLKPVK
EECCCCHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHH
SALAHHIPVVTVDSGLSPNISDCFLATSNVGAAAALAKYTADHLMGGKGQYAIVDFNHTA
HHHHHCCCEEEECCCCCCCCHHHEEEECCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCC
STGIARPKGFMLGMKSYPHIKKMGPIQYSNNDVSAGLRIATTMLTQYPHLKVIFGANDRA
CCCCCCCCCEEECCCCCCCHHHCCCEEECCCCHHCCHHHHHHHHHCCCCEEEEECCCCCC
ALGPAEAVQRAHAKVKVVGFDADLGEIALVKAGIIQASILQSPYDMGYYAVVALLDKLDG
CCCHHHHHHHHCCEEEEEEECCCCCCEEEHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCC
KTLPKRINTPYFLLTPKNLGSSQATAAIRQYAPKYNPAG
CCCCHHCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKLRKTLLGAAAVALLGGMAAAPAMAAAPTVHSLPVPAKPAKHYHFTLITKSNASPYWLA
CCHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCCCEEEE
VREGADAAAKKFGVSVAFEAPASGTDLAGQIGMVNNAVTGGTDGIILAAQNPQALLKPVK
EECCCCHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHH
SALAHHIPVVTVDSGLSPNISDCFLATSNVGAAAALAKYTADHLMGGKGQYAIVDFNHTA
HHHHHCCCEEEECCCCCCCCHHHEEEECCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCC
STGIARPKGFMLGMKSYPHIKKMGPIQYSNNDVSAGLRIATTMLTQYPHLKVIFGANDRA
CCCCCCCCCEEECCCCCCCHHHCCCEEECCCCHHCCHHHHHHHHHCCCCEEEEECCCCCC
ALGPAEAVQRAHAKVKVVGFDADLGEIALVKAGIIQASILQSPYDMGYYAVVALLDKLDG
CCCHHHHHHHHCCEEEEEEECCCCCCEEEHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCC
KTLPKRINTPYFLLTPKNLGSSQATAAIRQYAPKYNPAG
CCCCHHCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; ribose [Periplasm]; D-allose [Periplasm]; ATP [C]

Specific reaction: ATP + H2O + ribose [Periplasm] = ADP + phosphate + ribose [Cytoplasm] D-allose [Periplasm] + ATP + H2O = D-allose [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 8576032; 9401019; 10064713 [H]