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The map label for this gene is ucpA [C]

Identifier: 148260723

GI number: 148260723

Start: 1907384

End: 1908181

Strand: Reverse

Name: ucpA [C]

Synonym: Acry_1727

Alternate gene names: 148260723

Gene position: 1908181-1907384 (Counterclockwise)

Preceding gene: 148260724

Following gene: 148260719

Centisome position: 56.3

GC content: 72.06

Gene sequence:

>798_bases
ATGAAACCCGTCACCAGCGCCGACGGCATCGTCTGGATCACCGGCGCCTCCAGCGGCATCGGCCGCGCCCTGGCCGAGGC
GCATGTGGCGCAGGGCTGGCGCGTCGCCATCACCGCCCGGCGCGAGGCCGAGCTTCGCGCCCTCGCCGAAACCCATCCGA
GCCGCATCATCGTCGCGCCGGCCGACGTGACCGATCCCGACTCGGTGCGCGAGGCGGTGAACACCATCACCCGCGACGGC
CCGATCGCCCGCGCCATCCTCAACGCCGGCACCTATGAGCGCGACACCGCCGAAACCTTCACCGCCGATCGCCTGCGCCG
CCAGGTCGAGCTGAACCTGCTCGGCACCGCGCGCGGGCTCGAACTGGTGATGCCGGCGATGATCGCCCGCAAGCGCGGCC
AGATCGCGCTGATGTCCTCGCTCGCCGGCCTCGCCGGCCTGCCCGGCTCGGTCTCCTATTCGGCGACCAAGGCGGCGCTG
ATCGCCACCGCCGAAGCCCTGAAATTCGATCTCGACCGCCACGGCGTCGCGATCTCGGCGATCTGCCCCGGTTTCGTGAA
ATCGCCGCTCACCGCGAACAACCGCTTCCCGATGCCCTTCCTGATGGAAACCGACGCCGCCGCCCGCGCCATCCTGCGCG
GGCTCGATGCCGGGCGGTTCCTGATCGCCTTCCCCGAAGGCCTGGCCCGCCCGCTGCGCATCCTGCGCCTGCTGCCCCAT
GCCGCCTTCTTCCCGCTCGTCGCCCGCTTCACCGGGTCGCGCACGCCGGGCAGGGCGGAGCCGGACCCGGAGAGCTAG

Upstream 100 bases:

>100_bases
TGCCGGTGCGAACGTGGCACAAGATGGCGGAACCGAAGCGCCGCGCCCTGCGCGACCGCGCCGCCGAGCTGCGCCGCCGC
CTGCAACACGGAGACAGAAT

Downstream 100 bases:

>100_bases
TTCCCCATCGGGAAATCGAGCCCGGTGCTGCCGAACCCGCCCGCCTCGCGCGCGGTCCGGTCGAGATCGTCGGTCTCCTG
CCACACCAGCCGCGACACCG

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MKPVTSADGIVWITGASSGIGRALAEAHVAQGWRVAITARREAELRALAETHPSRIIVAPADVTDPDSVREAVNTITRDG
PIARAILNAGTYERDTAETFTADRLRRQVELNLLGTARGLELVMPAMIARKRGQIALMSSLAGLAGLPGSVSYSATKAAL
IATAEALKFDLDRHGVAISAICPGFVKSPLTANNRFPMPFLMETDAAARAILRGLDAGRFLIAFPEGLARPLRILRLLPH
AAFFPLVARFTGSRTPGRAEPDPES

Sequences:

>Translated_265_residues
MKPVTSADGIVWITGASSGIGRALAEAHVAQGWRVAITARREAELRALAETHPSRIIVAPADVTDPDSVREAVNTITRDG
PIARAILNAGTYERDTAETFTADRLRRQVELNLLGTARGLELVMPAMIARKRGQIALMSSLAGLAGLPGSVSYSATKAAL
IATAEALKFDLDRHGVAISAICPGFVKSPLTANNRFPMPFLMETDAAARAILRGLDAGRFLIAFPEGLARPLRILRLLPH
AAFFPLVARFTGSRTPGRAEPDPES
>Mature_265_residues
MKPVTSADGIVWITGASSGIGRALAEAHVAQGWRVAITARREAELRALAETHPSRIIVAPADVTDPDSVREAVNTITRDG
PIARAILNAGTYERDTAETFTADRLRRQVELNLLGTARGLELVMPAMIARKRGQIALMSSLAGLAGLPGSVSYSATKAAL
IATAEALKFDLDRHGVAISAICPGFVKSPLTANNRFPMPFLMETDAAARAILRGLDAGRFLIAFPEGLARPLRILRLLPH
AAFFPLVARFTGSRTPGRAEPDPES

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7706318, Length=197, Percent_Identity=35.5329949238579, Blast_Score=108, Evalue=6e-24,
Organism=Homo sapiens, GI210032110, Length=248, Percent_Identity=26.6129032258064, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI20149619, Length=196, Percent_Identity=27.5510204081633, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI40254992, Length=214, Percent_Identity=27.5700934579439, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI59889578, Length=166, Percent_Identity=35.5421686746988, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI210032112, Length=240, Percent_Identity=26.6666666666667, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI226371731, Length=191, Percent_Identity=24.6073298429319, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI40807363, Length=251, Percent_Identity=24.7011952191235, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI150247226, Length=199, Percent_Identity=31.1557788944724, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI4503817, Length=191, Percent_Identity=29.3193717277487, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI4758504, Length=199, Percent_Identity=30.1507537688442, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI157739938, Length=193, Percent_Identity=23.8341968911917, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI31542939, Length=189, Percent_Identity=29.6296296296296, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI223718074, Length=189, Percent_Identity=33.3333333333333, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI7657478, Length=181, Percent_Identity=30.939226519337, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI87082100, Length=183, Percent_Identity=32.2404371584699, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1787335, Length=183, Percent_Identity=30.0546448087432, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1786701, Length=185, Percent_Identity=29.1891891891892, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI2367175, Length=198, Percent_Identity=28.2828282828283, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790717, Length=187, Percent_Identity=29.4117647058824, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1787820, Length=189, Percent_Identity=27.5132275132275, Blast_Score=65, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17508895, Length=259, Percent_Identity=24.3243243243243, Blast_Score=81, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17567345, Length=192, Percent_Identity=26.5625, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17538486, Length=199, Percent_Identity=32.1608040201005, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17562904, Length=204, Percent_Identity=29.9019607843137, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17562990, Length=204, Percent_Identity=30.3921568627451, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17507613, Length=191, Percent_Identity=27.2251308900524, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI32563809, Length=191, Percent_Identity=27.2251308900524, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI72000259, Length=190, Percent_Identity=31.5789473684211, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI21358495, Length=195, Percent_Identity=28.7179487179487, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI116007236, Length=215, Percent_Identity=28.8372093023256, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI281364494, Length=201, Percent_Identity=31.8407960199005, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24580925, Length=200, Percent_Identity=29.5, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28571526, Length=194, Percent_Identity=29.3814432989691, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24640492, Length=254, Percent_Identity=25.9842519685039, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI23397609, Length=189, Percent_Identity=28.042328042328, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21356301, Length=229, Percent_Identity=29.2576419213974, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24640442, Length=188, Percent_Identity=26.063829787234, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI17737361, Length=200, Percent_Identity=27, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24581726, Length=195, Percent_Identity=25.1282051282051, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24649181, Length=252, Percent_Identity=24.6031746031746, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21357041, Length=192, Percent_Identity=27.0833333333333, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24644339, Length=194, Percent_Identity=26.8041237113402, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI116007238, Length=177, Percent_Identity=29.3785310734463, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 28236; Mature: 28236

Theoretical pI: Translated: 10.65; Mature: 10.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPVTSADGIVWITGASSGIGRALAEAHVAQGWRVAITARREAELRALAETHPSRIIVAP
CCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCEEEEEEECCHHHHHHHHHCCCCEEEEEC
ADVTDPDSVREAVNTITRDGPIARAILNAGTYERDTAETFTADRLRRQVELNLLGTARGL
CCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHEEEEECCCCH
ELVMPAMIARKRGQIALMSSLAGLAGLPGSVSYSATKAALIATAEALKFDLDRHGVAISA
HHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEH
ICPGFVKSPLTANNRFPMPFLMETDAAARAILRGLDAGRFLIAFPEGLARPLRILRLLPH
HCCHHHCCCCCCCCCCCCCEEECCHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHH
AAFFPLVARFTGSRTPGRAEPDPES
HHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKPVTSADGIVWITGASSGIGRALAEAHVAQGWRVAITARREAELRALAETHPSRIIVAP
CCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCEEEEEEECCHHHHHHHHHCCCCEEEEEC
ADVTDPDSVREAVNTITRDGPIARAILNAGTYERDTAETFTADRLRRQVELNLLGTARGL
CCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHEEEEECCCCH
ELVMPAMIARKRGQIALMSSLAGLAGLPGSVSYSATKAALIATAEALKFDLDRHGVAISA
HHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEH
ICPGFVKSPLTANNRFPMPFLMETDAAARAILRGLDAGRFLIAFPEGLARPLRILRLLPH
HCCHHHCCCCCCCCCCCCCEEECCHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHHHHH
AAFFPLVARFTGSRTPGRAEPDPES
HHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1730672 [H]