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The map label for this gene is lig [H]

Identifier: 148260610

GI number: 148260610

Start: 1778236

End: 1779300

Strand: Reverse

Name: lig [H]

Synonym: Acry_1612

Alternate gene names: 148260610

Gene position: 1779300-1778236 (Counterclockwise)

Preceding gene: 148260619

Following gene: 148260609

Centisome position: 52.5

GC content: 70.8

Gene sequence:

>1065_bases
ATGGCAGACTTGGCGAAACCTGCAATCCGCCCCCATCTTCCCGCCATGCCTCCGCATCCCGAAACCTGGCTGCACCCTCG
CCCCGAAGGGCTCCATTGCGTGCCGGGCGACTTCTTCATCGACCCCACCCGCGCCGTCGATCGCGCGGTGATCACCCATG
GCCATGCCGACCATGCCCGGCCGGGCCATCGCCATGTGCTGGCCAGCGCCGAGACGCTTGCGATCATGCGGGTGCGGATG
GGCGAGGCGCGGGCCGGCGCGGCGCAGCAGGCGGCCGCACCGGGCGAGATCGTCCGCATCAACGGCGTCGGCGTCTCCCT
CATCCCCGCCGGCCATGTCCTCGGCTCCTGCCAGGTGGTGCTGGACTATGAAGGCAGCCGCGCCGTGGTCTCGGGCGACT
ACAAGCGCCGGCGCGATCCCACCTGCGCGCCCTTCGTCCCGGTGAATTGCGACGTGTTCGTGACGGAGGCGACGTTCGGC
CTGCCGGTCTTCCGCCATCCGGACGCCGCGGCGGAAATCGCGAAACTGCTCCACTCCATGACGATCTTCCCCACCCGCGC
CCATCTCGTCGGCGCCTACGGTCTCGGCAAGGCGCAGCGGCTGATCGCCCTGCTGCGCGAAGCCGGATACGACGCTCCGA
TCTACCTCCACGGCGCCCTGCAAAAACTCTGCGACCTCTACGAAACCCTCGGCGTGCCCCTGGGCGATCTCCGCCCCGCC
ACGGTCGCCGACAAGGACGCGCTGAAAGGCGCCATCGTCCTCGCCCCGCCCTCCGCGGTGGCGGATCGCTGGGCGCGGCG
GCTGGATGATCCGGTGGTCGCCGTCGCCTCGGGCTGGATGCGGGTGCGCCAGCGCGCCAAGGCCTCCGGCGTCGAACTGC
CGCTCGTCATCTCCGACCATGCCGACTGGGGCGAACTGCTCGCCACGGTGGAGGATGTCGCCGCCCCGGAAATCTGGGTC
ACCCACGGCGCCGAGGCGGCCCTGCTGCGCCAGCTCTCGCTGATGGGCCGGCGCGGCCGCGCGCTCAGCCTGATCGGCTA
TGGCGACGAGGCGGAGCAGGAATGA

Upstream 100 bases:

>100_bases
GCGCCGCGTCCAGCACGGCGAGCTGGTGCGGCCGCGGCGTCCAGCCGCGCGCGGCGAACCAGTCGGCGAAACGGTGGGGC
AGGGCGGTCACGCGCCAGAC

Downstream 100 bases:

>100_bases
AACCCTTCGCCGATCTGCTGGAACGCCTGCTCTACACCACCGGGCGCAACGCCAAGATCGCGCTCCTCGCCGATTACTTC
GCCCACCGCCCCGATCCCGA

Product: RNA procession exonuclease-like protein

Products: NA

Alternate protein names: Polydeoxyribonucleotide synthase [ATP] [H]

Number of amino acids: Translated: 354; Mature: 353

Protein sequence:

>354_residues
MADLAKPAIRPHLPAMPPHPETWLHPRPEGLHCVPGDFFIDPTRAVDRAVITHGHADHARPGHRHVLASAETLAIMRVRM
GEARAGAAQQAAAPGEIVRINGVGVSLIPAGHVLGSCQVVLDYEGSRAVVSGDYKRRRDPTCAPFVPVNCDVFVTEATFG
LPVFRHPDAAAEIAKLLHSMTIFPTRAHLVGAYGLGKAQRLIALLREAGYDAPIYLHGALQKLCDLYETLGVPLGDLRPA
TVADKDALKGAIVLAPPSAVADRWARRLDDPVVAVASGWMRVRQRAKASGVELPLVISDHADWGELLATVEDVAAPEIWV
THGAEAALLRQLSLMGRRGRALSLIGYGDEAEQE

Sequences:

>Translated_354_residues
MADLAKPAIRPHLPAMPPHPETWLHPRPEGLHCVPGDFFIDPTRAVDRAVITHGHADHARPGHRHVLASAETLAIMRVRM
GEARAGAAQQAAAPGEIVRINGVGVSLIPAGHVLGSCQVVLDYEGSRAVVSGDYKRRRDPTCAPFVPVNCDVFVTEATFG
LPVFRHPDAAAEIAKLLHSMTIFPTRAHLVGAYGLGKAQRLIALLREAGYDAPIYLHGALQKLCDLYETLGVPLGDLRPA
TVADKDALKGAIVLAPPSAVADRWARRLDDPVVAVASGWMRVRQRAKASGVELPLVISDHADWGELLATVEDVAAPEIWV
THGAEAALLRQLSLMGRRGRALSLIGYGDEAEQE
>Mature_353_residues
ADLAKPAIRPHLPAMPPHPETWLHPRPEGLHCVPGDFFIDPTRAVDRAVITHGHADHARPGHRHVLASAETLAIMRVRMG
EARAGAAQQAAAPGEIVRINGVGVSLIPAGHVLGSCQVVLDYEGSRAVVSGDYKRRRDPTCAPFVPVNCDVFVTEATFGL
PVFRHPDAAAEIAKLLHSMTIFPTRAHLVGAYGLGKAQRLIALLREAGYDAPIYLHGALQKLCDLYETLGVPLGDLRPAT
VADKDALKGAIVLAPPSAVADRWARRLDDPVVAVASGWMRVRQRAKASGVELPLVISDHADWGELLATVEDVAAPEIWVT
HGAEAALLRQLSLMGRRGRALSLIGYGDEAEQE

Specific function: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair [H]

COG id: COG1236

COG function: function code J; Predicted exonuclease of the beta-lactamase fold involved in RNA processing

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the ATP- dependent DNA ligase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000977
- InterPro:   IPR012309
- InterPro:   IPR012310
- InterPro:   IPR016059
- InterPro:   IPR012308
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR011108 [H]

Pfam domain/function: PF04679 DNA_ligase_A_C; PF01068 DNA_ligase_A_M; PF04675 DNA_ligase_A_N; PF07521 RMMBL [H]

EC number: =6.5.1.1 [H]

Molecular weight: Translated: 38002; Mature: 37871

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADLAKPAIRPHLPAMPPHPETWLHPRPEGLHCVPGDFFIDPTRAVDRAVITHGHADHAR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCEECCHHHHHHHHHHCCCCCCCC
PGHRHVLASAETLAIMRVRMGEARAGAAQQAAAPGEIVRINGVGVSLIPAGHVLGSCQVV
CCCCEEHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCEEEEECCCEEEEECCCCCCCEEEE
LDYEGSRAVVSGDYKRRRDPTCAPFVPVNCDVFVTEATFGLPVFRHPDAAAEIAKLLHSM
EEECCCEEEEECCHHHCCCCCCCCEEECCCEEEEEEEECCCCCEECCCHHHHHHHHHHHH
TIFPTRAHLVGAYGLGKAQRLIALLREAGYDAPIYLHGALQKLCDLYETLGVPLGDLRPA
HCCCCHHHEEECCCCCHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHCCCCCCCCCC
TVADKDALKGAIVLAPPSAVADRWARRLDDPVVAVASGWMRVRQRAKASGVELPLVISDH
CCCCHHHHCCEEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECC
ADWGELLATVEDVAAPEIWVTHGAEAALLRQLSLMGRRGRALSLIGYGDEAEQE
CCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCC
>Mature Secondary Structure 
ADLAKPAIRPHLPAMPPHPETWLHPRPEGLHCVPGDFFIDPTRAVDRAVITHGHADHAR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCEECCHHHHHHHHHHCCCCCCCC
PGHRHVLASAETLAIMRVRMGEARAGAAQQAAAPGEIVRINGVGVSLIPAGHVLGSCQVV
CCCCEEHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCEEEEECCCEEEEECCCCCCCEEEE
LDYEGSRAVVSGDYKRRRDPTCAPFVPVNCDVFVTEATFGLPVFRHPDAAAEIAKLLHSM
EEECCCEEEEECCHHHCCCCCCCCEEECCCEEEEEEEECCCCCEECCCHHHHHHHHHHHH
TIFPTRAHLVGAYGLGKAQRLIALLREAGYDAPIYLHGALQKLCDLYETLGVPLGDLRPA
HCCCCHHHEEECCCCCHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHCCCCCCCCCC
TVADKDALKGAIVLAPPSAVADRWARRLDDPVVAVASGWMRVRQRAKASGVELPLVISDH
CCCCHHHHCCEEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECC
ADWGELLATVEDVAAPEIWVTHGAEAALLRQLSLMGRRGRALSLIGYGDEAEQE
CCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA