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The map label for this gene is csgA [H]

Identifier: 148260566

GI number: 148260566

Start: 1729087

End: 1729782

Strand: Reverse

Name: csgA [H]

Synonym: Acry_1568

Alternate gene names: 148260566

Gene position: 1729782-1729087 (Counterclockwise)

Preceding gene: 148260569

Following gene: 148260564

Centisome position: 51.04

GC content: 73.42

Gene sequence:

>696_bases
ATGGCATCGGAACCGTCCTGTCTCATCATCGGCGCCTCGCGCGGGCTCGGTCTCGCCATGGCGGAGGAGTATCTCGGGCG
CGGCTGGCGGGTGACGGCGACGGTGCGCGGCGCGGGGCCGACCGGCCTGCACGCGCTGGCGGCGCGGGCCGGCGGGCGGC
TCGCGATCGAGCGCCTCGACATCAACGACGCGGACCAGCTCGCCGCCCTGCGGGCGCGGCTGGAGGGGCAGGTGTTCGAC
CAGCTGTTCGTGAACGCGGGAATCGCCAGCGATCCGGCGGCGCCGATCGGCGCGGTGAGCACCGAGACCTTCGTCGAGCT
GATGGTGACCAACGCGCTCAGCCCGATGCGCGCGGTGGAGGCGCTGGGCGACCTGGTCGCGCCGGAGGGCGGGATCGGGC
TGATGTCTTCCGGGCTCGGCAGCGTGGCCAACAACACGACCGGCATGTTCGAGGCCTACCGGGCGAGCAAGGCGGCGCTG
AACACGCTGATGCGCAGCTATGCCGCGCGCCACAGGGACTCCGCGCGCAGCCTCGCCCTGGTGGCGCCCGGCTGGGTGCG
GACCGACATGGGCGGGCCGCAGGCGACGCTGTCGATCGGCGAGAGCATTCCCCGCGTGGTCGACCAGCTGATCGCCCGGC
GCGGCAGGCCGGGGCTGGCGTTCTTCGACTATACCGGCGCGGAGCTGCCGTGGTGA

Upstream 100 bases:

>100_bases
GACTGTTCCGCTTCGCCACGCCCGCGCCCCGCGGCGTCTGGCCGTGCGGGCGGGAATCGTCGTAGCCTCGGCGCGAAACC
GGGAATCGAGGAGAAGCGCC

Downstream 100 bases:

>100_bases
GGCGCTGAGGTGAGACGCTGACGCCGGTGTGGATACCTTTTCTCGGTATCTCGGCGTTCCGCAGACCGAACTATCTGCTG
ATGAAGCCCTTCAAGCGGCG

Product: short-chain dehydrogenase/reductase SDR

Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]

Alternate protein names: C signal [H]

Number of amino acids: Translated: 231; Mature: 230

Protein sequence:

>231_residues
MASEPSCLIIGASRGLGLAMAEEYLGRGWRVTATVRGAGPTGLHALAARAGGRLAIERLDINDADQLAALRARLEGQVFD
QLFVNAGIASDPAAPIGAVSTETFVELMVTNALSPMRAVEALGDLVAPEGGIGLMSSGLGSVANNTTGMFEAYRASKAAL
NTLMRSYAARHRDSARSLALVAPGWVRTDMGGPQATLSIGESIPRVVDQLIARRGRPGLAFFDYTGAELPW

Sequences:

>Translated_231_residues
MASEPSCLIIGASRGLGLAMAEEYLGRGWRVTATVRGAGPTGLHALAARAGGRLAIERLDINDADQLAALRARLEGQVFD
QLFVNAGIASDPAAPIGAVSTETFVELMVTNALSPMRAVEALGDLVAPEGGIGLMSSGLGSVANNTTGMFEAYRASKAAL
NTLMRSYAARHRDSARSLALVAPGWVRTDMGGPQATLSIGESIPRVVDQLIARRGRPGLAFFDYTGAELPW
>Mature_230_residues
ASEPSCLIIGASRGLGLAMAEEYLGRGWRVTATVRGAGPTGLHALAARAGGRLAIERLDINDADQLAALRARLEGQVFDQ
LFVNAGIASDPAAPIGAVSTETFVELMVTNALSPMRAVEALGDLVAPEGGIGLMSSGLGSVANNTTGMFEAYRASKAALN
TLMRSYAARHRDSARSLALVAPGWVRTDMGGPQATLSIGESIPRVVDQLIARRGRPGLAFFDYTGAELPW

Specific function: Cell-cell signaling protein required for fruiting body morphogenesis. Necessary for cellular aggregation, for spore differentiation, and for gene expression that is initiated after 6 hour of starvation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To yeast YKL071W [H]

Homologues:

Organism=Caenorhabditis elegans, GI17558990, Length=252, Percent_Identity=29.3650793650794, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI193207563, Length=225, Percent_Identity=29.3333333333333, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17559964, Length=235, Percent_Identity=31.063829787234, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24640547, Length=247, Percent_Identity=32.3886639676113, Blast_Score=92, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100 [C]

Molecular weight: Translated: 24108; Mature: 23977

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASEPSCLIIGASRGLGLAMAEEYLGRGWRVTATVRGAGPTGLHALAARAGGRLAIERLD
CCCCCCEEEEECCCCCCHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHCCCEEEEEEEC
INDADQLAALRARLEGQVFDQLFVNAGIASDPAAPIGAVSTETFVELMVTNALSPMRAVE
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHH
ALGDLVAPEGGIGLMSSGLGSVANNTTGMFEAYRASKAALNTLMRSYAARHRDSARSLAL
HHHHHHCCCCCCHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
VAPGWVRTDMGGPQATLSIGESIPRVVDQLIARRGRPGLAFFDYTGAELPW
ECCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCC
>Mature Secondary Structure 
ASEPSCLIIGASRGLGLAMAEEYLGRGWRVTATVRGAGPTGLHALAARAGGRLAIERLD
CCCCCEEEEECCCCCCHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHCCCEEEEEEEC
INDADQLAALRARLEGQVFDQLFVNAGIASDPAAPIGAVSTETFVELMVTNALSPMRAVE
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHH
ALGDLVAPEGGIGLMSSGLGSVANNTTGMFEAYRASKAALNTLMRSYAARHRDSARSLAL
HHHHHHCCCCCCHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
VAPGWVRTDMGGPQATLSIGESIPRVVDQLIARRGRPGLAFFDYTGAELPW
ECCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]

Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2152896; 2107980; 2118510; 1372277 [H]