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The map label for this gene is degP [H]

Identifier: 148260327

GI number: 148260327

Start: 1480764

End: 1482173

Strand: Reverse

Name: degP [H]

Synonym: Acry_1324

Alternate gene names: 148260327

Gene position: 1482173-1480764 (Counterclockwise)

Preceding gene: 148260328

Following gene: 148260324

Centisome position: 43.73

GC content: 70.57

Gene sequence:

>1410_bases
ATGATGCGTTTCGCGATTTTGGTTCCGACCGCCGGCGCGGCCCTCGCGCTCGGCCTGCTGCTGTCCTCGTCCCCGGCCCA
TGCCGTGCCGGCGCCGCCCGCGGTCGCGCAGGTGGCGCGCGCGGCGCTGCCCGCCGTGGTGGATATCGAGAGCATCGATC
CCTCCAAGGGAAAGGGCGACAAGTCCGGCGAGATGCCGCCGCCCGACCAGGGGGCGGCGGCGCCTTCGAAATCGGAGCCG
GCGGACACGAGCACGCTGATCGTGCCGCCGAAGGCCGAGCAGGCGCTCGGCACCGGGTTCTTCATCAGCCCGACCGGCTA
TATCGTCACCAATCATCACGTCATCGCCGGGGCGAGCGAGATCAAGGTGACGATGCATGACGGCTCGATCTTCACCGCGA
AGCTGGTCGGCTCGGACAAGAAGGCCGATCTCGCGGTGCTGAAGATCGACGCGCATCATCCGGTGCCCTTCCTGCATTTC
GGCGACAGCTCGCAGCTGGTGCTCGGCGACTGGGTGGTGGCGATCGGCAATCCGTTCGGCCTCGGCTTCAGCGTGTCGGC
GGGGGTGGTGAGCGCGCTGCACCGCGACATCGGCTCGGGACCGTATGACGATTTCATCCAGACCGACGCCGCCATCAACC
GCGGCAATTCGGGCGGGCCGCTGCTGGACGCGAAGGGGGAGGTCATCGGCGTCGATTCGGCGATCTACTCGCCTTCGGGC
GGGTCGGTCGGGATCGGGTTCGCGATTCCGTCGAGCATGGTGCGGCCGGTGGCGGCGGCGATCATCGCCGATGGCGCGAT
GAAGCGCGGCTGGGCGGGGCTGCGGATCGAGCATGTGTCGGAGGACATGAAGGCGGCCTGGCATCTGGCCTCGACCGATG
GGGTGGTGGTCGGCGGCGTGGTCGCGGACGGGCCTTCCGCCGGCAAGCTCGGCCCGGGCGACGTGGTGACGGCGGTGAAC
GGCCGGAAGGTGGCCACGGTGCATGATTTCAAGGTCGCGCTGGCGGAGATCCCGGTCGGGCACGAGGCGCGGATGACCTA
TGAACGCGGCGGCAGGACGGAGGAGGCGGCGATCACGATCGAGCCGGCGCCGGCCGCCAAGGGAAAGACCGGCAAGCCGG
CGGCGAAGCCGGCGCTGGTTCCGACGGAAATTCCGGCGCTCGGCATCGGTGTGGCCGCGCATCCGGGCGGGGCGGGCGTG
ATCGTGATCACGGTCGCCAAGGATGGCCCGGCGGCGCGGGCCGGGCTGCTCCCGGATACGCTGATCGAGGCCGTCGGGCC
GCATTTCGTCACGACCGCGGCGGCCTTGCAGGACGGCGTGAAGGCGAGCCGGAACGTCGTGCCGCTGCTGGTGGGCGGGC
CGGCGGGAACGAGCTGGATCGTCGTGCCGCTGGGCGACGGGGCCGGCTGA

Upstream 100 bases:

>100_bases
GCGGCGACGCTGCGCGATCTGCGGGACGCCGGGGCCACGCCCGCGCAAATCCGCGAGATGGTCTCTTGCCGGATCGGCGA
TCTCGCCTCACTCTGACAGG

Downstream 100 bases:

>100_bases
AAGCGTGCCCCGGCCGGGCGGCGTGCCCGGCCGGGGACGGCGGCTTGCGACCAGACGATTGAACGGCCTTCCGGCGCGCC
GGGCCGTCAGTTCGCGCGGG

Product: 2-alkenal reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 469; Mature: 469

Protein sequence:

>469_residues
MMRFAILVPTAGAALALGLLLSSSPAHAVPAPPAVAQVARAALPAVVDIESIDPSKGKGDKSGEMPPPDQGAAAPSKSEP
ADTSTLIVPPKAEQALGTGFFISPTGYIVTNHHVIAGASEIKVTMHDGSIFTAKLVGSDKKADLAVLKIDAHHPVPFLHF
GDSSQLVLGDWVVAIGNPFGLGFSVSAGVVSALHRDIGSGPYDDFIQTDAAINRGNSGGPLLDAKGEVIGVDSAIYSPSG
GSVGIGFAIPSSMVRPVAAAIIADGAMKRGWAGLRIEHVSEDMKAAWHLASTDGVVVGGVVADGPSAGKLGPGDVVTAVN
GRKVATVHDFKVALAEIPVGHEARMTYERGGRTEEAAITIEPAPAAKGKTGKPAAKPALVPTEIPALGIGVAAHPGGAGV
IVITVAKDGPAARAGLLPDTLIEAVGPHFVTTAAALQDGVKASRNVVPLLVGGPAGTSWIVVPLGDGAG

Sequences:

>Translated_469_residues
MMRFAILVPTAGAALALGLLLSSSPAHAVPAPPAVAQVARAALPAVVDIESIDPSKGKGDKSGEMPPPDQGAAAPSKSEP
ADTSTLIVPPKAEQALGTGFFISPTGYIVTNHHVIAGASEIKVTMHDGSIFTAKLVGSDKKADLAVLKIDAHHPVPFLHF
GDSSQLVLGDWVVAIGNPFGLGFSVSAGVVSALHRDIGSGPYDDFIQTDAAINRGNSGGPLLDAKGEVIGVDSAIYSPSG
GSVGIGFAIPSSMVRPVAAAIIADGAMKRGWAGLRIEHVSEDMKAAWHLASTDGVVVGGVVADGPSAGKLGPGDVVTAVN
GRKVATVHDFKVALAEIPVGHEARMTYERGGRTEEAAITIEPAPAAKGKTGKPAAKPALVPTEIPALGIGVAAHPGGAGV
IVITVAKDGPAARAGLLPDTLIEAVGPHFVTTAAALQDGVKASRNVVPLLVGGPAGTSWIVVPLGDGAG
>Mature_469_residues
MMRFAILVPTAGAALALGLLLSSSPAHAVPAPPAVAQVARAALPAVVDIESIDPSKGKGDKSGEMPPPDQGAAAPSKSEP
ADTSTLIVPPKAEQALGTGFFISPTGYIVTNHHVIAGASEIKVTMHDGSIFTAKLVGSDKKADLAVLKIDAHHPVPFLHF
GDSSQLVLGDWVVAIGNPFGLGFSVSAGVVSALHRDIGSGPYDDFIQTDAAINRGNSGGPLLDAKGEVIGVDSAIYSPSG
GSVGIGFAIPSSMVRPVAAAIIADGAMKRGWAGLRIEHVSEDMKAAWHLASTDGVVVGGVVADGPSAGKLGPGDVVTAVN
GRKVATVHDFKVALAEIPVGHEARMTYERGGRTEEAAITIEPAPAAKGKTGKPAAKPALVPTEIPALGIGVAAHPGGAGV
IVITVAKDGPAARAGLLPDTLIEAVGPHFVTTAAALQDGVKASRNVVPLLVGGPAGTSWIVVPLGDGAG

Specific function: Protease With A Shared Specificity With Degp. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=251, Percent_Identity=36.6533864541833, Blast_Score=148, Evalue=8e-36,
Organism=Homo sapiens, GI22129776, Length=270, Percent_Identity=34.8148148148148, Blast_Score=138, Evalue=1e-32,
Organism=Homo sapiens, GI24308541, Length=256, Percent_Identity=37.109375, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI7019477, Length=279, Percent_Identity=32.6164874551971, Blast_Score=115, Evalue=6e-26,
Organism=Escherichia coli, GI1789629, Length=450, Percent_Identity=34.2222222222222, Blast_Score=226, Evalue=2e-60,
Organism=Escherichia coli, GI1786356, Length=372, Percent_Identity=34.4086021505376, Blast_Score=214, Evalue=1e-56,
Organism=Escherichia coli, GI1789630, Length=280, Percent_Identity=35, Blast_Score=155, Evalue=7e-39,
Organism=Drosophila melanogaster, GI24646839, Length=266, Percent_Identity=34.9624060150376, Blast_Score=125, Evalue=5e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.-

Molecular weight: Translated: 46924; Mature: 46924

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMRFAILVPTAGAALALGLLLSSSPAHAVPAPPAVAQVARAALPAVVDIESIDPSKGKGD
CEEEEEEECCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCCCC
KSGEMPPPDQGAAAPSKSEPADTSTLIVPPKAEQALGTGFFISPTGYIVTNHHVIAGASE
CCCCCCCCCCCCCCCCCCCCCCCCEEEECCCHHHHHCCCEEECCCCEEEECCEEEECCCE
IKVTMHDGSIFTAKLVGSDKKADLAVLKIDAHHPVPFLHFGDSSQLVLGDWVVAIGNPFG
EEEEEECCCEEEEEEECCCCCCCEEEEEEECCCCCCEEEECCCCCEEEEEEEEEECCCCC
LGFSVSAGVVSALHRDIGSGPYDDFIQTDAAINRGNSGGPLLDAKGEVIGVDSAIYSPSG
CCEEHHHHHHHHHHHHHCCCCCHHHHHCCHHHCCCCCCCCEEECCCCEEEECCEEECCCC
GSVGIGFAIPSSMVRPVAAAIIADGAMKRGWAGLRIEHVSEDMKAAWHLASTDGVVVGGV
CCEEEEECCCHHHHHHHHHHHHHCCHHHCCCCCEEEHHHHHHHHHHEEEECCCCEEEEEE
VADGPSAGKLGPGDVVTAVNGRKVATVHDFKVALAEIPVGHEARMTYERGGRTEEAAITI
EECCCCCCCCCCCCEEEEECCCEEEEEEHEEEEEECCCCCCCCEEEHHHCCCCCCEEEEE
EPAPAAKGKTGKPAAKPALVPTEIPALGIGVAAHPGGAGVIVITVAKDGPAARAGLLPDT
ECCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCEEEEEEEECCCCCCCCCCCHHH
LIEAVGPHFVTTAAALQDGVKASRNVVPLLVGGPAGTSWIVVPLGDGAG
HHHHCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCEEEEEECCCCCC
>Mature Secondary Structure
MMRFAILVPTAGAALALGLLLSSSPAHAVPAPPAVAQVARAALPAVVDIESIDPSKGKGD
CEEEEEEECCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCCCC
KSGEMPPPDQGAAAPSKSEPADTSTLIVPPKAEQALGTGFFISPTGYIVTNHHVIAGASE
CCCCCCCCCCCCCCCCCCCCCCCCEEEECCCHHHHHCCCEEECCCCEEEECCEEEECCCE
IKVTMHDGSIFTAKLVGSDKKADLAVLKIDAHHPVPFLHFGDSSQLVLGDWVVAIGNPFG
EEEEEECCCEEEEEEECCCCCCCEEEEEEECCCCCCEEEECCCCCEEEEEEEEEECCCCC
LGFSVSAGVVSALHRDIGSGPYDDFIQTDAAINRGNSGGPLLDAKGEVIGVDSAIYSPSG
CCEEHHHHHHHHHHHHHCCCCCHHHHHCCHHHCCCCCCCCEEECCCCEEEECCEEECCCC
GSVGIGFAIPSSMVRPVAAAIIADGAMKRGWAGLRIEHVSEDMKAAWHLASTDGVVVGGV
CCEEEEECCCHHHHHHHHHHHHHCCHHHCCCCCEEEHHHHHHHHHHEEEECCCCEEEEEE
VADGPSAGKLGPGDVVTAVNGRKVATVHDFKVALAEIPVGHEARMTYERGGRTEEAAITI
EECCCCCCCCCCCCEEEEECCCEEEEEEHEEEEEECCCCCCCCEEEHHHCCCCCCEEEEE
EPAPAAKGKTGKPAAKPALVPTEIPALGIGVAAHPGGAGVIVITVAKDGPAARAGLLPDT
ECCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCEEEEEEEECCCCCCCCCCCHHH
LIEAVGPHFVTTAAALQDGVKASRNVVPLLVGGPAGTSWIVVPLGDGAG
HHHHCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7861951 [H]