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The map label for this gene is yqeC [H]

Identifier: 148260279

GI number: 148260279

Start: 1424312

End: 1425316

Strand: Reverse

Name: yqeC [H]

Synonym: Acry_1276

Alternate gene names: 148260279

Gene position: 1425316-1424312 (Counterclockwise)

Preceding gene: 148260280

Following gene: 148260278

Centisome position: 42.05

GC content: 65.67

Gene sequence:

>1005_bases
ATGAAGATTGGTGTGATCGGCCTTGGCCGGATGGGCGCCAACATTGTCCGCCGGCTGATGCGAGACGGCCACGACTGTGT
GGTTTTCGACAAATCGGCAGAATCCGTCGAAAAGCTCGAGAAGGAAGGGGCGACCGGCGTGCGCGATCTCGCAGGCCTCG
TGAAGGCTCTGGAGCCACCGCGTTCGGTCTGGGTGATGCTTCCGGCCGGGCAGGTGACGAGCGAGACCGTCGACGCGCTC
GGCGACCTTCTCGGGCAGGATGACGTGGTCATCGATGGCGGCAACAGCTTCTATCGCGACGATATCGCCCATGCCGCGCG
GTTGAAACGCAAGGGCATCCATTTCGTCGATGTCGGTACCTCGGGCGGAGTCTGGGGGCTCGAACGCGGCTACTGCATGA
TGATCGGGGGCGACGACGCCATCGTCTGGCGGCTCGACCCCGTGTTTCGAACCCTGGCGCCGGGGCGTGGGGAAATCGAA
CCGACGCCGGGGCGCGAGGGACGGGACGAGCGTGCCGAGCTTGGCTACATCCATGCCGGCCCGAACGGCGCCGGGCATTT
CGTGAAGATGGTGCACAACGGCATCGAATACGGGTTGATGCAGGCCTATGCGGAAGGCTTCGCGATCCTGCGCAACCGCT
GCGCCGATGCGTTGCCCGAAGCCGAACGCTACGACCTCGATGTCGCCGACATTGCCGAGGTGTGGCGGCGCGGCAGCGTG
ATCTCGTCCTGGCTGCTCGACCTGACCGCCGCGGCACTGGCGCGCGACGGGGCGCTTTCCGACTACAGCGGCTATGTCGA
GGATTCCGGCGAGGGACGCTGGACGATCAACGCCGCGATCGAGGAGGCGGTTCCGGCCGATGTGCTCACCGCCGCACTCT
ATGCGCGGTTCCGCTCCCGGCTCGATCATACGTTCGGCGAGAAGATCCTGTCTGCCATGCGACAGGGCTTCGGCGGTCAT
GTCGAGCAGGGACCGGCTGCTGCCAAGCAGGGAGGTGGCGCATGA

Upstream 100 bases:

>100_bases
CCGCGCCCGACCGGAGACCATTGACGAGCGTCATGCCCGGCGGCCCCGCGTCGTGGGACCGTCAGCGGCATGGCGCGGCA
ACAGGAACGGAGACAGAGCC

Downstream 100 bases:

>100_bases
ACCCGCTGGCAAAACACCCGCTCCGGTCAGAGGCCGGATCCTCCGGCGCCGCCTCGGCCTCCCCCGCGGGCCCCTGCAGC
GTCGTGATTTTCGGTGCCGC

Product: 6-phosphogluconate dehydrogenase-like protein

Products: D-ribulose 5-phosphate; CO2; NADPH

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MKIGVIGLGRMGANIVRRLMRDGHDCVVFDKSAESVEKLEKEGATGVRDLAGLVKALEPPRSVWVMLPAGQVTSETVDAL
GDLLGQDDVVIDGGNSFYRDDIAHAARLKRKGIHFVDVGTSGGVWGLERGYCMMIGGDDAIVWRLDPVFRTLAPGRGEIE
PTPGREGRDERAELGYIHAGPNGAGHFVKMVHNGIEYGLMQAYAEGFAILRNRCADALPEAERYDLDVADIAEVWRRGSV
ISSWLLDLTAAALARDGALSDYSGYVEDSGEGRWTINAAIEEAVPADVLTAALYARFRSRLDHTFGEKILSAMRQGFGGH
VEQGPAAAKQGGGA

Sequences:

>Translated_334_residues
MKIGVIGLGRMGANIVRRLMRDGHDCVVFDKSAESVEKLEKEGATGVRDLAGLVKALEPPRSVWVMLPAGQVTSETVDAL
GDLLGQDDVVIDGGNSFYRDDIAHAARLKRKGIHFVDVGTSGGVWGLERGYCMMIGGDDAIVWRLDPVFRTLAPGRGEIE
PTPGREGRDERAELGYIHAGPNGAGHFVKMVHNGIEYGLMQAYAEGFAILRNRCADALPEAERYDLDVADIAEVWRRGSV
ISSWLLDLTAAALARDGALSDYSGYVEDSGEGRWTINAAIEEAVPADVLTAALYARFRSRLDHTFGEKILSAMRQGFGGH
VEQGPAAAKQGGGA
>Mature_334_residues
MKIGVIGLGRMGANIVRRLMRDGHDCVVFDKSAESVEKLEKEGATGVRDLAGLVKALEPPRSVWVMLPAGQVTSETVDAL
GDLLGQDDVVIDGGNSFYRDDIAHAARLKRKGIHFVDVGTSGGVWGLERGYCMMIGGDDAIVWRLDPVFRTLAPGRGEIE
PTPGREGRDERAELGYIHAGPNGAGHFVKMVHNGIEYGLMQAYAEGFAILRNRCADALPEAERYDLDVADIAEVWRRGSV
ISSWLLDLTAAALARDGALSDYSGYVEDSGEGRWTINAAIEEAVPADVLTAALYARFRSRLDHTFGEKILSAMRQGFGGH
VEQGPAAAKQGGGA

Specific function: May act as NAD-dependent 6-P-gluconate dehydrogenase [H]

COG id: COG1023

COG function: function code G; Predicted 6-phosphogluconate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 6-phosphogluconate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI40068518, Length=309, Percent_Identity=32.6860841423948, Blast_Score=126, Evalue=2e-29,
Organism=Escherichia coli, GI1788341, Length=321, Percent_Identity=30.8411214953271, Blast_Score=145, Evalue=4e-36,
Organism=Caenorhabditis elegans, GI17542558, Length=309, Percent_Identity=32.0388349514563, Blast_Score=134, Evalue=8e-32,
Organism=Saccharomyces cerevisiae, GI6321695, Length=312, Percent_Identity=28.2051282051282, Blast_Score=119, Evalue=7e-28,
Organism=Saccharomyces cerevisiae, GI6321977, Length=314, Percent_Identity=28.9808917197452, Blast_Score=113, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24639279, Length=311, Percent_Identity=29.903536977492, Blast_Score=110, Evalue=9e-25,
Organism=Drosophila melanogaster, GI24655230, Length=143, Percent_Identity=32.8671328671329, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI19922568, Length=143, Percent_Identity=32.8671328671329, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR004849
- InterPro:   IPR006114
- InterPro:   IPR006115
- InterPro:   IPR006184
- InterPro:   IPR013328
- InterPro:   IPR016040
- InterPro:   IPR006183 [H]

Pfam domain/function: PF00393 6PGD; PF03446 NAD_binding_2 [H]

EC number: 1.1.1.44

Molecular weight: Translated: 35908; Mature: 35908

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIGVIGLGRMGANIVRRLMRDGHDCVVFDKSAESVEKLEKEGATGVRDLAGLVKALEPP
CEEEEEECCHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHCCCCCHHHHHHHHHHCCCC
RSVWVMLPAGQVTSETVDALGDLLGQDDVVIDGGNSFYRDDIAHAARLKRKGIHFVDVGT
CCEEEEECCCCHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHCCCEEEEECC
SGGVWGLERGYCMMIGGDDAIVWRLDPVFRTLAPGRGEIEPTPGREGRDERAELGYIHAG
CCCCCCCCCCEEEEEECCCEEEEEECHHHHHHCCCCCCCCCCCCCCCCCCHHHEEEEECC
PNGAGHFVKMVHNGIEYGLMQAYAEGFAILRNRCADALPEAERYDLDVADIAEVWRRGSV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCHHHHHHHHHCCHH
ISSWLLDLTAAALARDGALSDYSGYVEDSGEGRWTINAAIEEAVPADVLTAALYARFRSR
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEHHHHHHCCHHHHHHHHHHHHHHH
LDHTFGEKILSAMRQGFGGHVEQGPAAAKQGGGA
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCC
>Mature Secondary Structure
MKIGVIGLGRMGANIVRRLMRDGHDCVVFDKSAESVEKLEKEGATGVRDLAGLVKALEPP
CEEEEEECCHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHCCCCCHHHHHHHHHHCCCC
RSVWVMLPAGQVTSETVDALGDLLGQDDVVIDGGNSFYRDDIAHAARLKRKGIHFVDVGT
CCEEEEECCCCHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHCCCEEEEECC
SGGVWGLERGYCMMIGGDDAIVWRLDPVFRTLAPGRGEIEPTPGREGRDERAELGYIHAG
CCCCCCCCCCEEEEEECCCEEEEEECHHHHHHCCCCCCCCCCCCCCCCCCHHHEEEEECC
PNGAGHFVKMVHNGIEYGLMQAYAEGFAILRNRCADALPEAERYDLDVADIAEVWRRGSV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCHHHHHHHHHCCHH
ISSWLLDLTAAALARDGALSDYSGYVEDSGEGRWTINAAIEEAVPADVLTAALYARFRSR
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEHHHHHHCCHHHHHHHHHHHHHHH
LDHTFGEKILSAMRQGFGGHVEQGPAAAKQGGGA
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 0.05 {6-phosphogluconate}} 0.01 {6-phosphogluconate}} [C]

Substrates: 6-phospho-D-gluconate; NADP+

Specific reaction: 6-phospho-D-gluconate + NADP+ = D-ribulose 5-phosphate + CO2 + NADPH

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]