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The map label for this gene is hipO [H]

Identifier: 148260215

GI number: 148260215

Start: 1348720

End: 1349874

Strand: Reverse

Name: hipO [H]

Synonym: Acry_1211

Alternate gene names: 148260215

Gene position: 1349874-1348720 (Counterclockwise)

Preceding gene: 148260216

Following gene: 148260214

Centisome position: 39.83

GC content: 67.53

Gene sequence:

>1155_bases
ATGCCCGACACGCACGCCCAACGCATCGCGCCCACGCTCACCGAATGGCGCCGATACCTGCATCAGCACCCCGAACTCTC
GCTGCGCGAGGAAAAGACCGCCGCCTTCGTCTGCGAGAGGCTGAAGGAACTCGGCATCCCCTTCGAGTCGGGCATTGGCG
GGCATGGGGTCGTCGCCACCCTGCGGCGCGGCGGCAATCGCAGCGTCGGCCTGCGCGCGGATATGGACGCGCTGCCGATC
ACCGAGGCGACGGGGCTGCCTTACGCCTCGAAAACGCCGGGCGTGATGCATGCCTGCGGGCATGATGGCCACACCACCTC
GCTCCTCGGCGCGGCGATGTTGCTGCGAGACGATCCGGACTGGTCGGGTACGGTGCATTTCGTCTTCCAGCCGGCCGAGG
AGGGCTTCGGCGGCGCCCTGGCGATGATGGAAGACGGGCTCTTCCGCCGCTTCCCGATGGAGCGCATCTTCGGCTACCAC
AACTGGCCGGGGGTCGAGGCCGGCGCGATCATGATCCATGACGGGCCGATGATGGCCCAGGGCGAGCGCATCGGCATCAC
CATCCACGGCCATGCCGGCCACGCCGCGATGCCGAACCTAACCGCAGACCCGGTGGTTTGCGCCGCGCAGATCATCGTCG
CGCTGCAATCGGTGGTCTCGCGCAACATCAACCCGCTCGATGCCGCGGTGATTTCGATCTGCGTGCTGCGCGGTGCCGAG
GCCGACAACCAGATTCCGGACACGGTGACGCTGCGCGGCACGGTCCGCGCCCTGCTGCCGGAGGTATTCGACCATGTCAC
CGGCCGCATTCGCGAGATCGTCGCCCATACGGCCTCCGCGATGGGCTGCCGCGGCGAGGTGATATTCGAGCGCCGCCTCG
CCGCGACGATCAACCACAAGGACGAGGCCGCACTCGGCCGCCGCGTGGCGCGGGACCTTGGCATGCCCGTGCTGACCGAT
CTGCCGCCAACCATGGCAAGCGAGGATTTCGGGTGGTATCTGCGGGAAATTCCTGGCGCCTATGCCTGGATCGGCAACGG
GCCGGCCACCGAGGGAGCCTTCCTGCACAACCAGAACTACAATTTCAACGACGAGATCCTGCCCATCGCTGCCGGCTATC
TCGCATCGACGGCGAAGGCCGCCCTGGCGGGCTGA

Upstream 100 bases:

>100_bases
CAGGTCAGAGACATTCTTTTCAGGCCATTCGCGCGCCCCCTTGCCGCAGGGGCGCGGCGGCGCATACTCTGGACCGAGAG
CTCATACAGGTGATCGATCC

Downstream 100 bases:

>100_bases
CGCGTGCCTGCGCCGGACGATTTCCGCTCGCACACGTCCGCTCCGCTTCCGGCTGGAACCCGCCGCGACATCGCCCGCCG
GTTGGCCGGCGGTCCGACCG

Product: amidohydrolase

Products: NA

Alternate protein names: Benzoylglycine amidohydrolase; Hippuricase [H]

Number of amino acids: Translated: 384; Mature: 383

Protein sequence:

>384_residues
MPDTHAQRIAPTLTEWRRYLHQHPELSLREEKTAAFVCERLKELGIPFESGIGGHGVVATLRRGGNRSVGLRADMDALPI
TEATGLPYASKTPGVMHACGHDGHTTSLLGAAMLLRDDPDWSGTVHFVFQPAEEGFGGALAMMEDGLFRRFPMERIFGYH
NWPGVEAGAIMIHDGPMMAQGERIGITIHGHAGHAAMPNLTADPVVCAAQIIVALQSVVSRNINPLDAAVISICVLRGAE
ADNQIPDTVTLRGTVRALLPEVFDHVTGRIREIVAHTASAMGCRGEVIFERRLAATINHKDEAALGRRVARDLGMPVLTD
LPPTMASEDFGWYLREIPGAYAWIGNGPATEGAFLHNQNYNFNDEILPIAAGYLASTAKAALAG

Sequences:

>Translated_384_residues
MPDTHAQRIAPTLTEWRRYLHQHPELSLREEKTAAFVCERLKELGIPFESGIGGHGVVATLRRGGNRSVGLRADMDALPI
TEATGLPYASKTPGVMHACGHDGHTTSLLGAAMLLRDDPDWSGTVHFVFQPAEEGFGGALAMMEDGLFRRFPMERIFGYH
NWPGVEAGAIMIHDGPMMAQGERIGITIHGHAGHAAMPNLTADPVVCAAQIIVALQSVVSRNINPLDAAVISICVLRGAE
ADNQIPDTVTLRGTVRALLPEVFDHVTGRIREIVAHTASAMGCRGEVIFERRLAATINHKDEAALGRRVARDLGMPVLTD
LPPTMASEDFGWYLREIPGAYAWIGNGPATEGAFLHNQNYNFNDEILPIAAGYLASTAKAALAG
>Mature_383_residues
PDTHAQRIAPTLTEWRRYLHQHPELSLREEKTAAFVCERLKELGIPFESGIGGHGVVATLRRGGNRSVGLRADMDALPIT
EATGLPYASKTPGVMHACGHDGHTTSLLGAAMLLRDDPDWSGTVHFVFQPAEEGFGGALAMMEDGLFRRFPMERIFGYHN
WPGVEAGAIMIHDGPMMAQGERIGITIHGHAGHAAMPNLTADPVVCAAQIIVALQSVVSRNINPLDAAVISICVLRGAEA
DNQIPDTVTLRGTVRALLPEVFDHVTGRIREIVAHTASAMGCRGEVIFERRLAATINHKDEAALGRRVARDLGMPVLTDL
PPTMASEDFGWYLREIPGAYAWIGNGPATEGAFLHNQNYNFNDEILPIAAGYLASTAKAALAG

Specific function: Required But Not Essential For Aminobenzoyl-Glutamate Utilization. May Participate In Hydrolysis Of Aminobenzoyl- Glutamate To Aminobenzoate, Either Alone Or In Combination With Abgb. [C]

COG id: COG1473

COG function: function code R; Metal-dependent amidase/aminoacylase/carboxypeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20 family [H]

Homologues:

Organism=Escherichia coli, GI87081880, Length=432, Percent_Identity=28.0092592592593, Blast_Score=86, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017439
- InterPro:   IPR010168
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.32 [H]

Molecular weight: Translated: 41397; Mature: 41266

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDTHAQRIAPTLTEWRRYLHQHPELSLREEKTAAFVCERLKELGIPFESGIGGHGVVAT
CCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHCCCCCCHHHHH
LRRGGNRSVGLRADMDALPITEATGLPYASKTPGVMHACGHDGHTTSLLGAAMLLRDDPD
HHCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHCCCCC
WSGTVHFVFQPAEEGFGGALAMMEDGLFRRFPMERIFGYHNWPGVEAGAIMIHDGPMMAQ
CCCEEEEEEECCCCCCCCCHHHHHCCHHHHCCHHHHCCCCCCCCCCCCEEEEECCCCEEC
GERIGITIHGHAGHAAMPNLTADPVVCAAQIIVALQSVVSRNINPLDAAVISICVLRGAE
CCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCC
ADNQIPDTVTLRGTVRALLPEVFDHVTGRIREIVAHTASAMGCRGEVIFERRLAATINHK
CCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCC
DEAALGRRVARDLGMPVLTDLPPTMASEDFGWYLREIPGAYAWIGNGPATEGAFLHNQNY
HHHHHHHHHHHHCCCCHHHCCCCCCCCCHHHHHHHHCCCCEEEECCCCCCCCEEEECCCC
NFNDEILPIAAGYLASTAKAALAG
CCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PDTHAQRIAPTLTEWRRYLHQHPELSLREEKTAAFVCERLKELGIPFESGIGGHGVVAT
CCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCHHCCCCCCHHHHH
LRRGGNRSVGLRADMDALPITEATGLPYASKTPGVMHACGHDGHTTSLLGAAMLLRDDPD
HHCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHCCCCC
WSGTVHFVFQPAEEGFGGALAMMEDGLFRRFPMERIFGYHNWPGVEAGAIMIHDGPMMAQ
CCCEEEEEEECCCCCCCCCHHHHHCCHHHHCCHHHHCCCCCCCCCCCCEEEEECCCCEEC
GERIGITIHGHAGHAAMPNLTADPVVCAAQIIVALQSVVSRNINPLDAAVISICVLRGAE
CCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCC
ADNQIPDTVTLRGTVRALLPEVFDHVTGRIREIVAHTASAMGCRGEVIFERRLAATINHK
CCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCC
DEAALGRRVARDLGMPVLTDLPPTMASEDFGWYLREIPGAYAWIGNGPATEGAFLHNQNY
HHHHHHHHHHHHCCCCHHHCCCCCCCCCHHHHHHHHCCCCEEEECCCCCCCCEEEECCCC
NFNDEILPIAAGYLASTAKAALAG
CCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7730270; 10688204 [H]