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The map label for this gene is agaR [H]

Identifier: 148260148

GI number: 148260148

Start: 1274605

End: 1275438

Strand: Reverse

Name: agaR [H]

Synonym: Acry_1144

Alternate gene names: 148260148

Gene position: 1275438-1274605 (Counterclockwise)

Preceding gene: 148260149

Following gene: 148260147

Centisome position: 37.63

GC content: 70.74

Gene sequence:

>834_bases
ATGAGGCGACGATCGGCATCTACCCGCGAGGGGCGGCAAGACCTCCTGCCCGTGCAGCGCCAGGCGCTGATTCTCGACCA
TGTCCGCCAGCACGGCGCGGCATCGATCCATGATCTGGCGGCGGCGATCGGCTCCTCGGTCTCGACGATCCGGCGCGATC
TCGACCGGCTGGAGAAGCGGCGGGCCCTGGCGCGCGCGCATGGCGGCGCGGCCCTGCCGGCCGAACCCGCCGCGACGTTC
GAACCCGCCCCGGAACTCGCAGAACAACTCGCGCGCGCGGAAAAGCGCCTGATCGGTGCCGCCGCCGCGGACATGCTCGC
ACCGGGCGAGAGCGTCATCTTCGACAGCGGCAGCACCGTGCGGTGGGCGGCCCAGGCCGCCATGGCGCGGGCGATCCCGC
TCACCGCGGTCACCAACGATCTCGGCATTGCCCAGGTTCTCGCGCAATCCGAGACGATCAGGGTCATCGTCTCCGGCGGC
ACGGTTCGCCACGGCTCGCTCAGCCTGACCGGCGATCCGGGACGCGACTTCCTGGCCGGGCTCCATGCCGATACGCTGCT
GCTCGGCACGCACACGATCAGCGGCACGGCGATCACCGACACCTCGGTGGAGATCGCGGCGATGAAGCGGGCGATGATCC
GCGCGGCGCGACGGGTCATTCTCCTCGCGGACTCGACGAAGTTCCGCCTGCCGGCCTTCTGCACGATCTGCGATCTCGAC
GAGATCGACGCGCTGGTGACCGATGACGGCGTTGATCCGGGCGATCTCGATGCGGCGCGCGCGCGGGGCGTGACGGTCTC
GCTCGTCTCGGCGCCGCGCGAAACGCCCCGATGA

Upstream 100 bases:

>100_bases
GGGGGTAACGCCGGCGGCCTACCGCCGGCACTTTGGCGGAAGGGCGTAACGCGCGGCGCCGGCATTTGGCAAACGCAACC
GGCTGTGAGACATTTTTGCG

Downstream 100 bases:

>100_bases
CGACCTCGGTCCGCCTTGTTGCCGATGATCTGACCGGCGCGCTCGATGCGGCCGTCCAGTTCACGGGGCGAAATCCGGGC
CTTCCGGTGCTTCTTCGCGC

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 277; Mature: 277

Protein sequence:

>277_residues
MRRRSASTREGRQDLLPVQRQALILDHVRQHGAASIHDLAAAIGSSVSTIRRDLDRLEKRRALARAHGGAALPAEPAATF
EPAPELAEQLARAEKRLIGAAAADMLAPGESVIFDSGSTVRWAAQAAMARAIPLTAVTNDLGIAQVLAQSETIRVIVSGG
TVRHGSLSLTGDPGRDFLAGLHADTLLLGTHTISGTAITDTSVEIAAMKRAMIRAARRVILLADSTKFRLPAFCTICDLD
EIDALVTDDGVDPGDLDAARARGVTVSLVSAPRETPR

Sequences:

>Translated_277_residues
MRRRSASTREGRQDLLPVQRQALILDHVRQHGAASIHDLAAAIGSSVSTIRRDLDRLEKRRALARAHGGAALPAEPAATF
EPAPELAEQLARAEKRLIGAAAADMLAPGESVIFDSGSTVRWAAQAAMARAIPLTAVTNDLGIAQVLAQSETIRVIVSGG
TVRHGSLSLTGDPGRDFLAGLHADTLLLGTHTISGTAITDTSVEIAAMKRAMIRAARRVILLADSTKFRLPAFCTICDLD
EIDALVTDDGVDPGDLDAARARGVTVSLVSAPRETPR
>Mature_277_residues
MRRRSASTREGRQDLLPVQRQALILDHVRQHGAASIHDLAAAIGSSVSTIRRDLDRLEKRRALARAHGGAALPAEPAATF
EPAPELAEQLARAEKRLIGAAAADMLAPGESVIFDSGSTVRWAAQAAMARAIPLTAVTNDLGIAQVLAQSETIRVIVSGG
TVRHGSLSLTGDPGRDFLAGLHADTLLLGTHTISGTAITDTSVEIAAMKRAMIRAARRVILLADSTKFRLPAFCTICDLD
EIDALVTDDGVDPGDLDAARARGVTVSLVSAPRETPR

Specific function: Probable repressor for the aga operon for N-acetyl galactosamine transport and metabolism [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789519, Length=252, Percent_Identity=33.7301587301587, Blast_Score=141, Evalue=5e-35,
Organism=Escherichia coli, GI1789059, Length=259, Percent_Identity=32.8185328185328, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI226510968, Length=237, Percent_Identity=32.4894514767932, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1789829, Length=231, Percent_Identity=31.1688311688312, Blast_Score=103, Evalue=9e-24,
Organism=Escherichia coli, GI87082344, Length=234, Percent_Identity=30.3418803418803, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI1788069, Length=241, Percent_Identity=31.1203319502075, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1790635, Length=249, Percent_Identity=25.3012048192771, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787540, Length=255, Percent_Identity=28.2352941176471, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1790753, Length=231, Percent_Identity=25.1082251082251, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1789170, Length=256, Percent_Identity=25.78125, Blast_Score=64, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 29222; Mature: 29222

Theoretical pI: Translated: 7.72; Mature: 7.72

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRRSASTREGRQDLLPVQRQALILDHVRQHGAASIHDLAAAIGSSVSTIRRDLDRLEKR
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHH
RALARAHGGAALPAEPAATFEPAPELAEQLARAEKRLIGAAAADMLAPGESVIFDSGSTV
HHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCH
RWAAQAAMARAIPLTAVTNDLGIAQVLAQSETIRVIVSGGTVRHGSLSLTGDPGRDFLAG
HHHHHHHHHHHCCHHHHHCCHHHHHHHHCCCEEEEEEECCEEECCEEEECCCCCHHHHHH
LHADTLLLGTHTISGTAITDTSVEIAAMKRAMIRAARRVILLADSTKFRLPAFCTICDLD
HCCCEEEEEEEEECCCEEECCCHHHHHHHHHHHHHHCEEEEEECCCCCCCCEEEEEECHH
EIDALVTDDGVDPGDLDAARARGVTVSLVSAPRETPR
HHHHEEECCCCCCCCCCHHHHCCCEEEEEECCCCCCC
>Mature Secondary Structure
MRRRSASTREGRQDLLPVQRQALILDHVRQHGAASIHDLAAAIGSSVSTIRRDLDRLEKR
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHH
RALARAHGGAALPAEPAATFEPAPELAEQLARAEKRLIGAAAADMLAPGESVIFDSGSTV
HHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCH
RWAAQAAMARAIPLTAVTNDLGIAQVLAQSETIRVIVSGGTVRHGSLSLTGDPGRDFLAG
HHHHHHHHHHHCCHHHHHCCHHHHHHHHCCCEEEEEEECCEEECCEEEECCCCCHHHHHH
LHADTLLLGTHTISGTAITDTSVEIAAMKRAMIRAARRVILLADSTKFRLPAFCTICDLD
HCCCEEEEEEEEECCCEEECCCHHHHHHHHHHHHHHCEEEEEECCCCCCCCEEEEEECHH
EIDALVTDDGVDPGDLDAARARGVTVSLVSAPRETPR
HHHHEEECCCCCCCCCCHHHHCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]