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The map label for this gene is pdxA1 [H]

Identifier: 148260146

GI number: 148260146

Start: 1272301

End: 1273350

Strand: Reverse

Name: pdxA1 [H]

Synonym: Acry_1142

Alternate gene names: 148260146

Gene position: 1273350-1272301 (Counterclockwise)

Preceding gene: 148260147

Following gene: 148260145

Centisome position: 37.57

GC content: 68.67

Gene sequence:

>1050_bases
GTGGCCATTCCGCGTATTGCCGTCACGATGGGGGATCCGGCCGGTGTCGGCCCGGAAATCATCGCGAAGGCTGCCCTGCG
CCTGAAGGACCGGATCGAGGCCGGCGAGCTCGCGCTGGTGGTGACGGGGTCCGGCCACCGCCTCGCCGCCGCTTGCGCCG
GGTTGGGCATTGCCCAGCCTTTCGCTGCCGTTTCCGCCGATACCCCGCGCGAGGCGCTGCCGCCTTGTGCGCTGGTCGAG
GTCGGGCCCGACGCCTCTGCCATCGAGCCGGGCAAGGTTTCGGCCGTCGCGGGCGAAAGCGCCTATCAGGCGATCGCCGC
CGGCGTGCGCATGGCGATGGGCGGCCTGGTCGATGCGATCTGCACGGCGCCGATCAACAAGGAGGCGCTCAATCTCGCCG
GCCATCATTACAGCGGCCATACCGAGCTGCTTGCCGATCTCACCGCCGCGCGGAATTCGGTGATGATGCTGGCCCATGGC
AACATGCGCGTGAGCCATGTCTGCACCCATGTCGCGCTGCGCGACGTGCCGAAGCGCCTCACGCCCGAGCGGCTGCGTCA
GGTGGTGGAACTGACAGCGGACGCGCTGAACCGGCTGGGCATCGCCCGCCCGCGGATCGGCATCGCCGCGCTCAATCCGC
ATGCCGGCGAGAACGGCCTGTTCGGCCGCGAGGATATCGACATCACCGCCCCCACCGTCGAGGATCTGCGTCGCGCCGGC
CACGACGTGACCGGTCCGGTTCCGGGCGACACGATCTTCGTGAAACTGCGGGCCGGCCAGTTCGACGCGGTCGTCGCGAT
GTATCACGATCAGGGCCATATTCCGGTGAAGCTGCTGGGCTTTTCGGTCGATCCCACGACCGGCGAATGGCAGGCGCTCA
GCGGCGTCAACGTCACGCTCGGCCTGCCGATCATCCGCACGTCGGTCGACCACGGCACGGCGTTCGACATTGCCGGCAAG
GGCATCGCCAGCGAGCAGAGCCTGCTGGAAGCCATCGACTACGCGGTGCAACTCGCGCAAGGATCGGACCGGACCGCGCC
CTCACCGTAA

Upstream 100 bases:

>100_bases
GAACCGAGGCGTTTCAAAATCAATCATAAAACATGATCGTTATTGACACAGAGGCGGCCGCGGCTCATGTTCGCGCCGTC
ACGAGACCGGAGGTGCATTG

Downstream 100 bases:

>100_bases
CGCAACGACCCGCCACGGCGCGCCGGTCAGGGCGTGCCGATCGATGACAAACGGCCGGACGCGGGCTCTGCCCGGGCGGT
CACAAAGGGAGGATAATATT

Product: 4-hydroxythreonine-4-phosphate dehydrogenase

Products: NA

Alternate protein names: 4-(phosphohydroxy)-L-threonine dehydrogenase 1 [H]

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MAIPRIAVTMGDPAGVGPEIIAKAALRLKDRIEAGELALVVTGSGHRLAAACAGLGIAQPFAAVSADTPREALPPCALVE
VGPDASAIEPGKVSAVAGESAYQAIAAGVRMAMGGLVDAICTAPINKEALNLAGHHYSGHTELLADLTAARNSVMMLAHG
NMRVSHVCTHVALRDVPKRLTPERLRQVVELTADALNRLGIARPRIGIAALNPHAGENGLFGREDIDITAPTVEDLRRAG
HDVTGPVPGDTIFVKLRAGQFDAVVAMYHDQGHIPVKLLGFSVDPTTGEWQALSGVNVTLGLPIIRTSVDHGTAFDIAGK
GIASEQSLLEAIDYAVQLAQGSDRTAPSP

Sequences:

>Translated_349_residues
MAIPRIAVTMGDPAGVGPEIIAKAALRLKDRIEAGELALVVTGSGHRLAAACAGLGIAQPFAAVSADTPREALPPCALVE
VGPDASAIEPGKVSAVAGESAYQAIAAGVRMAMGGLVDAICTAPINKEALNLAGHHYSGHTELLADLTAARNSVMMLAHG
NMRVSHVCTHVALRDVPKRLTPERLRQVVELTADALNRLGIARPRIGIAALNPHAGENGLFGREDIDITAPTVEDLRRAG
HDVTGPVPGDTIFVKLRAGQFDAVVAMYHDQGHIPVKLLGFSVDPTTGEWQALSGVNVTLGLPIIRTSVDHGTAFDIAGK
GIASEQSLLEAIDYAVQLAQGSDRTAPSP
>Mature_348_residues
AIPRIAVTMGDPAGVGPEIIAKAALRLKDRIEAGELALVVTGSGHRLAAACAGLGIAQPFAAVSADTPREALPPCALVEV
GPDASAIEPGKVSAVAGESAYQAIAAGVRMAMGGLVDAICTAPINKEALNLAGHHYSGHTELLADLTAARNSVMMLAHGN
MRVSHVCTHVALRDVPKRLTPERLRQVVELTADALNRLGIARPRIGIAALNPHAGENGLFGREDIDITAPTVEDLRRAGH
DVTGPVPGDTIFVKLRAGQFDAVVAMYHDQGHIPVKLLGFSVDPTTGEWQALSGVNVTLGLPIIRTSVDHGTAFDIAGKG
IASEQSLLEAIDYAVQLAQGSDRTAPSP

Specific function: Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) [H]

COG id: COG1995

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxA family [H]

Homologues:

Organism=Escherichia coli, GI1786237, Length=342, Percent_Identity=36.5497076023392, Blast_Score=200, Evalue=1e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005255 [H]

Pfam domain/function: PF04166 PdxA [H]

EC number: =1.1.1.262 [H]

Molecular weight: Translated: 36184; Mature: 36053

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIPRIAVTMGDPAGVGPEIIAKAALRLKDRIEAGELALVVTGSGHRLAAACAGLGIAQP
CCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHCCCCCCC
FAAVSADTPREALPPCALVEVGPDASAIEPGKVSAVAGESAYQAIAAGVRMAMGGLVDAI
HHHHCCCCCHHHCCCEEEEEECCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHH
CTAPINKEALNLAGHHYSGHTELLADLTAARNSVMMLAHGNMRVSHVCTHVALRDVPKRL
HCCCCCHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHCC
TPERLRQVVELTADALNRLGIARPRIGIAALNPHAGENGLFGREDIDITAPTVEDLRRAG
CHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCEECCCHHHHHHCC
HDVTGPVPGDTIFVKLRAGQFDAVVAMYHDQGHIPVKLLGFSVDPTTGEWQALSGVNVTL
CCCCCCCCCCEEEEEEECCCCEEEEEEEECCCCCEEEEEEEEECCCCCCCEEECCCEEEE
GLPIIRTSVDHGTAFDIAGKGIASEQSLLEAIDYAVQLAQGSDRTAPSP
CCCEEEECCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
AIPRIAVTMGDPAGVGPEIIAKAALRLKDRIEAGELALVVTGSGHRLAAACAGLGIAQP
CCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHCCCCCCC
FAAVSADTPREALPPCALVEVGPDASAIEPGKVSAVAGESAYQAIAAGVRMAMGGLVDAI
HHHHCCCCCHHHCCCEEEEEECCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHH
CTAPINKEALNLAGHHYSGHTELLADLTAARNSVMMLAHGNMRVSHVCTHVALRDVPKRL
HCCCCCHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHCC
TPERLRQVVELTADALNRLGIARPRIGIAALNPHAGENGLFGREDIDITAPTVEDLRRAG
CHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCEECCCHHHHHHCC
HDVTGPVPGDTIFVKLRAGQFDAVVAMYHDQGHIPVKLLGFSVDPTTGEWQALSGVNVTL
CCCCCCCCCCEEEEEEECCCCEEEEEEEECCCCCEEEEEEEEECCCCCCCEEECCCEEEE
GLPIIRTSVDHGTAFDIAGKGIASEQSLLEAIDYAVQLAQGSDRTAPSP
CCCEEEECCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]