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The map label for this gene is putA [H]

Identifier: 148260047

GI number: 148260047

Start: 1153735

End: 1157547

Strand: Reverse

Name: putA [H]

Synonym: Acry_1039

Alternate gene names: 148260047

Gene position: 1157547-1153735 (Counterclockwise)

Preceding gene: 148260055

Following gene: 148260045

Centisome position: 34.15

GC content: 71.52

Gene sequence:

>3813_bases
ATGGCTGTCAGCACGATGGGGGTCAAGCTCGACGATCAGGTCCGCGCCCGGCTCCGCGCCCTGGCCGAGCGCGAGGGACG
GACGACGCATCACCTCGCCAAGCAGCTCATTCTCGCCGGGCTGGAGCGGCTCGAACGCGGCGAGGCGCTCGACGCCGCCG
TCACCGCCGAGGACGATGCGCCCGCTGCCGTGCCCTTCCTCGAATTCGTCCAGGACGTGCAGCCGCAGACGGTGCTGCGC
GCCGCGATCACCGCCGCCTACCGGATCCCGGAAACCGACGCCGTCGCCGGGCTGATCGAGGGCGCGACCCTGCCCGCCGC
CGCCGCGAAACAGGCGCGGGCGACCGCGACCAATCTCGTCACCGCGCTGCGCGCCCGCCGCAATGCCGGCCTGGTCGAGA
CGCTGCTGCAGGAATACGCGCTGTCGAGCCACGAGGGCATCGCGCTGATGTGCCTCGCCGAGGCGCTGCTCCGCATCCCC
GACGCCGCCACGCGCGACGCGCTGATCCGCGACAAGATCGGCGCCGGCGACTGGCAGAGCCATCTCGGCGGCAACAAGTC
GGTCTTCATCAACGCCGCCACCTGGGGGCTGCTGCTCACCGGCAGGCTGAACGCCACCGCGAGCGAGGCCGGCCTGTCCT
CGGCGCTGACCCGGCTGCTCGCCCGCGGCGGCGAGCCGGTGGTCCGCCGCGGCGTGAACATCGCGATGCGGCTGATGGGC
GAGCAGTTCGTCATGGGCCGGACCATCGGCGAGGCGTTGGCCAATGCCCGCAAGCGCGAGGCGAAGGGCTTCGCCTATTC
CTACGACATGCTGGGCGAGGCGGCACTCACCGCCGCCGATGCCGCGCGCTACTACCGCGACTACGAACAGGCGATCCACG
CGATCGGCGCCGCCGCGGGCGGCAAGGGGATCTATCGCGGCCCCGGCATTTCGGTGAAGCTCTCGGCGCTGCATCCGCGT
TACTGCCGCGCCCAGCGCGCGCGGGTGATGGAGGAGCTGGCGCCGCGGCTCAAGGCGCTGGCCCTGCTCGCCCGCCGCTA
CGATATCGGCATCAATATCGACGCCGAGGAAGCCGACCGGCTCGACCTCTCGCTCGACCTGCTGGAAGGCCTCTGCTTCG
AGCCGGGCCTCGCCGGCTGGAACGGCATCGGCTTCGTGGTGCAGGCCTACCAGAAGCGCGCGCGATCGGTGATCGAGTTC
CTGATCGACCTCGCCCGCCGCAGCCGCCACCGGCTGATGGTCCGGCTGGTCAAGGGCGCGTATTGGGACAGCGAGATCAA
GCGCGCCCAGCTCGACGGGCTGGAAGGTTTCCCGGTCTTCACCCGCAAGATCCACACCGACCTGTCCTATCTCGCCTGCG
CGCGGGCGATGCTGGCGGCGCGCACCGAGATCTTCCCGCAATTCGCGACGCATAACGCGCTGACGCTGGCGAGCATCCAC
GCCCTGGCCGGACCCGCCTTCGAGGTGGGGGACTACGAGTTCCAGTGCCTGCACGGCATGGGCGAGCCGCTCTACGAGGA
AGTCGTCGGCCCGCAGAAGCTCGACCGGCCCTGCCGGATCTACGCGCCGGTCGGCACCCATGAGACGCTGCTCGCCTATC
TCGTCCGCCGGTTGCTGGAGAACGGCGCCAACACCTCCTTCGTCAACCGCCTCGCCGATCGCCGCGTGCCGGTCGAAGCC
CTGATCGAGGACCCGGTCGCCGCCGCGAGAAAGATCGAGCCGCTCGGCGCGCCGCATCCGAAGATCGCGCTGCCGGGCGC
GATTCTGGGCACGCGGCGCAATTCCGCCGGATTTGATCTCACCAGCGAGCAGCGCCTCGCCTCGCTCGGCTCGGCCCTGC
TGGCAAGCCTCGAACAGGACTGGCGCGCCGCCCCGCCGGATGCCGATCCGGCCGCGCCGGGGCGGACCGTGGTCAACCCG
GCGAATATCGCCGACCGCGTCGGCACCGTCATCGAGCCGGATGCGGGCGCGGTCGGCGCCGCGCTCGCCCGCGCCGCCGC
CATGGCGCCGATCTGGCAGGCGACGCCTGCCGCCGAGCGCGCCGCGATCCTGCTTCGCGCCGCCGACCTGCTCGAACACC
GGATGACGGCGCTGGTCGGGCTGATCGTGCGCGAGGCCGGCAAGTCGCTCCCGGCGGCGATCGGCGAGGTGCGCGAGGCG
GTCGATTTCATGCGCTATTACGCGGGCCAGCTGCAGGATGGGTTCGACAACGAGACGCATCGCCCGCTCGGCGTGGTGGC
GGCGATCAGCCCGTGGAATTTCCCGCTCGCCATCTTCACCGGCCAGGTGGTCGCCGCACTCGCCGCCGGCAATGTGGTGC
TCGCCAAGCCGGCGGAGGAAACCCCGCTGATCGCCGCTCAGGGCGTGCGGATAATGCACGAGGCCGGCGTGCCGGCGGAT
GCGTTGCAGCTGCTGCCGGGCGATGGGCGGACGGGTGCCGCGCTGGTGGGGGATGCCAGGGTCGGCGGCGTGGTGTTCAC
CGGTTCGACCGCCGTCGCCCGGCTGATCCAGGCCACGCTCGCCCGGCGCCTCGATGCCGATGGGATGCCGGTGCCGCTGA
TCGCCGAGACCGGCGGGCAGAACGCGATGCTGGTCGATTCCTCGGCGCTGCTGGAACAGGCGGTGGGCGATATCGTGACC
TCGGCCTTCGATTCCGCGGGGCAGCGCTGCTCGGCCCTGCGCATCCTGCTGGTGCAGGACGACATTGCGGATCCGCTGCT
CGCCATGCTGCGCGGGGCGATGGAGGAACTCGCCGTGGGGGCGACCGACCGGTTGTCGAGCGATGTGGGCCCGGTGATCA
CGCGGGAGGCGCGGGACAATATCCGCGCCCATGTCGAGACGATGGAAGGGCGGGGGCATAAGGTATTCTCGGTGGCGCTG
CCGCCGGAGACCGAGGGCGGGTGGTTCGTGGCGCCGACGATGATCGAGATCGACCATCCCTCGGCACTGGAGCGCGAGGT
GTTCGGGCCGGTGCTGCACGTGGTGCGTTACCGGCGCGAGGAGCGGAATGCGATGGTCGCCGCGGTGAACGCGCTGGGCT
ATGCGCTCACCTTCGGCGTGCACAGCCGGATCGACGAGACGATCGCGCAGGCGGTGGGCAAGGCCGAGGCCGGCAACATC
TACGTCAACCGCAACATCGTCGGCGCCGTGGTCGGCGTGCAGCCCTTCGGCGGGCATGGGCTGTCGGGCACCGGGCCGAA
GGCGGGCGGGCCGTTCTACCTGCGCCGGCTGCTGGCACGGCGGCCGATGCCGCATGGCGAGGGCGAGCCGGCGCCGGCGT
TCACGAAGCTGGTCGGCTGGATGCGCGAGCAGGGGATCGAGACCGCGCCGGCGCTCCGCTATGCGGCGGCTTCGGCGTTC
CGCGACGCCGAGCTGCCGGGGCCGGTGGGCGAGCAGAATACCCTGCGGCTGAAGCCGAAGGGGCTTGTGCTCTGCCGGGC
CGCGAGCCCCGAGGGCATGTGGCGCCAGGTCGCCGCCTGCCTTGCCACCGGCAATGCGCCGCTGGTGCTCTGCGACGGCG
CCGAGGCGGAGATCGCCCGGATGCCGGCGGAGATCCGCCCGGCGATCGCGCCCGCCGATGCGGTGGCGCGGGCGGAATTC
AGCGCCGTGCTGTTCGAGGGCCATCGCGACGCGCTGATCGCGCTGCAGATGGCGCTGGCGGAGCGGGACGGGCCGATCGT
GCCGGTCCACGCCCTGCCGGCGGAGGACCATTCCGAGTGGGATTATCCGCTCGAATTCCTCCTCGAGGAGCAGTCGATCA
GCGTCAACACCGCGGCGGCCGGGGGTAATGCCAGCCTGATGTCGATCGGCTGA

Upstream 100 bases:

>100_bases
TCATAGGGTGCACCGCAGCAACGAATTGGGTTGCACCTTTTCTCACAAAAGGTGTAACCCGCTCTGCATCGCAGGTGCAA
CCGCAACAGGAGGAACGGCG

Downstream 100 bases:

>100_bases
TTTTTTGCTCCGCGGCCATTTAGGGCTTAATCAAAGCCCGTACGGCCGCCAGCGCTTCATCAGCTTTGCTCGCATCAGGA
CCGCCGGCTTGGGCCATGTC

Product: delta-1-pyrroline-5-carboxylate dehydrogenase

Products: NA

Alternate protein names: Proline dehydrogenase; Proline oxidase; Delta-1-pyrroline-5-carboxylate dehydrogenase; P5C dehydrogenase [H]

Number of amino acids: Translated: 1270; Mature: 1269

Protein sequence:

>1270_residues
MAVSTMGVKLDDQVRARLRALAEREGRTTHHLAKQLILAGLERLERGEALDAAVTAEDDAPAAVPFLEFVQDVQPQTVLR
AAITAAYRIPETDAVAGLIEGATLPAAAAKQARATATNLVTALRARRNAGLVETLLQEYALSSHEGIALMCLAEALLRIP
DAATRDALIRDKIGAGDWQSHLGGNKSVFINAATWGLLLTGRLNATASEAGLSSALTRLLARGGEPVVRRGVNIAMRLMG
EQFVMGRTIGEALANARKREAKGFAYSYDMLGEAALTAADAARYYRDYEQAIHAIGAAAGGKGIYRGPGISVKLSALHPR
YCRAQRARVMEELAPRLKALALLARRYDIGINIDAEEADRLDLSLDLLEGLCFEPGLAGWNGIGFVVQAYQKRARSVIEF
LIDLARRSRHRLMVRLVKGAYWDSEIKRAQLDGLEGFPVFTRKIHTDLSYLACARAMLAARTEIFPQFATHNALTLASIH
ALAGPAFEVGDYEFQCLHGMGEPLYEEVVGPQKLDRPCRIYAPVGTHETLLAYLVRRLLENGANTSFVNRLADRRVPVEA
LIEDPVAAARKIEPLGAPHPKIALPGAILGTRRNSAGFDLTSEQRLASLGSALLASLEQDWRAAPPDADPAAPGRTVVNP
ANIADRVGTVIEPDAGAVGAALARAAAMAPIWQATPAAERAAILLRAADLLEHRMTALVGLIVREAGKSLPAAIGEVREA
VDFMRYYAGQLQDGFDNETHRPLGVVAAISPWNFPLAIFTGQVVAALAAGNVVLAKPAEETPLIAAQGVRIMHEAGVPAD
ALQLLPGDGRTGAALVGDARVGGVVFTGSTAVARLIQATLARRLDADGMPVPLIAETGGQNAMLVDSSALLEQAVGDIVT
SAFDSAGQRCSALRILLVQDDIADPLLAMLRGAMEELAVGATDRLSSDVGPVITREARDNIRAHVETMEGRGHKVFSVAL
PPETEGGWFVAPTMIEIDHPSALEREVFGPVLHVVRYRREERNAMVAAVNALGYALTFGVHSRIDETIAQAVGKAEAGNI
YVNRNIVGAVVGVQPFGGHGLSGTGPKAGGPFYLRRLLARRPMPHGEGEPAPAFTKLVGWMREQGIETAPALRYAAASAF
RDAELPGPVGEQNTLRLKPKGLVLCRAASPEGMWRQVAACLATGNAPLVLCDGAEAEIARMPAEIRPAIAPADAVARAEF
SAVLFEGHRDALIALQMALAERDGPIVPVHALPAEDHSEWDYPLEFLLEEQSISVNTAAAGGNASLMSIG

Sequences:

>Translated_1270_residues
MAVSTMGVKLDDQVRARLRALAEREGRTTHHLAKQLILAGLERLERGEALDAAVTAEDDAPAAVPFLEFVQDVQPQTVLR
AAITAAYRIPETDAVAGLIEGATLPAAAAKQARATATNLVTALRARRNAGLVETLLQEYALSSHEGIALMCLAEALLRIP
DAATRDALIRDKIGAGDWQSHLGGNKSVFINAATWGLLLTGRLNATASEAGLSSALTRLLARGGEPVVRRGVNIAMRLMG
EQFVMGRTIGEALANARKREAKGFAYSYDMLGEAALTAADAARYYRDYEQAIHAIGAAAGGKGIYRGPGISVKLSALHPR
YCRAQRARVMEELAPRLKALALLARRYDIGINIDAEEADRLDLSLDLLEGLCFEPGLAGWNGIGFVVQAYQKRARSVIEF
LIDLARRSRHRLMVRLVKGAYWDSEIKRAQLDGLEGFPVFTRKIHTDLSYLACARAMLAARTEIFPQFATHNALTLASIH
ALAGPAFEVGDYEFQCLHGMGEPLYEEVVGPQKLDRPCRIYAPVGTHETLLAYLVRRLLENGANTSFVNRLADRRVPVEA
LIEDPVAAARKIEPLGAPHPKIALPGAILGTRRNSAGFDLTSEQRLASLGSALLASLEQDWRAAPPDADPAAPGRTVVNP
ANIADRVGTVIEPDAGAVGAALARAAAMAPIWQATPAAERAAILLRAADLLEHRMTALVGLIVREAGKSLPAAIGEVREA
VDFMRYYAGQLQDGFDNETHRPLGVVAAISPWNFPLAIFTGQVVAALAAGNVVLAKPAEETPLIAAQGVRIMHEAGVPAD
ALQLLPGDGRTGAALVGDARVGGVVFTGSTAVARLIQATLARRLDADGMPVPLIAETGGQNAMLVDSSALLEQAVGDIVT
SAFDSAGQRCSALRILLVQDDIADPLLAMLRGAMEELAVGATDRLSSDVGPVITREARDNIRAHVETMEGRGHKVFSVAL
PPETEGGWFVAPTMIEIDHPSALEREVFGPVLHVVRYRREERNAMVAAVNALGYALTFGVHSRIDETIAQAVGKAEAGNI
YVNRNIVGAVVGVQPFGGHGLSGTGPKAGGPFYLRRLLARRPMPHGEGEPAPAFTKLVGWMREQGIETAPALRYAAASAF
RDAELPGPVGEQNTLRLKPKGLVLCRAASPEGMWRQVAACLATGNAPLVLCDGAEAEIARMPAEIRPAIAPADAVARAEF
SAVLFEGHRDALIALQMALAERDGPIVPVHALPAEDHSEWDYPLEFLLEEQSISVNTAAAGGNASLMSIG
>Mature_1269_residues
AVSTMGVKLDDQVRARLRALAEREGRTTHHLAKQLILAGLERLERGEALDAAVTAEDDAPAAVPFLEFVQDVQPQTVLRA
AITAAYRIPETDAVAGLIEGATLPAAAAKQARATATNLVTALRARRNAGLVETLLQEYALSSHEGIALMCLAEALLRIPD
AATRDALIRDKIGAGDWQSHLGGNKSVFINAATWGLLLTGRLNATASEAGLSSALTRLLARGGEPVVRRGVNIAMRLMGE
QFVMGRTIGEALANARKREAKGFAYSYDMLGEAALTAADAARYYRDYEQAIHAIGAAAGGKGIYRGPGISVKLSALHPRY
CRAQRARVMEELAPRLKALALLARRYDIGINIDAEEADRLDLSLDLLEGLCFEPGLAGWNGIGFVVQAYQKRARSVIEFL
IDLARRSRHRLMVRLVKGAYWDSEIKRAQLDGLEGFPVFTRKIHTDLSYLACARAMLAARTEIFPQFATHNALTLASIHA
LAGPAFEVGDYEFQCLHGMGEPLYEEVVGPQKLDRPCRIYAPVGTHETLLAYLVRRLLENGANTSFVNRLADRRVPVEAL
IEDPVAAARKIEPLGAPHPKIALPGAILGTRRNSAGFDLTSEQRLASLGSALLASLEQDWRAAPPDADPAAPGRTVVNPA
NIADRVGTVIEPDAGAVGAALARAAAMAPIWQATPAAERAAILLRAADLLEHRMTALVGLIVREAGKSLPAAIGEVREAV
DFMRYYAGQLQDGFDNETHRPLGVVAAISPWNFPLAIFTGQVVAALAAGNVVLAKPAEETPLIAAQGVRIMHEAGVPADA
LQLLPGDGRTGAALVGDARVGGVVFTGSTAVARLIQATLARRLDADGMPVPLIAETGGQNAMLVDSSALLEQAVGDIVTS
AFDSAGQRCSALRILLVQDDIADPLLAMLRGAMEELAVGATDRLSSDVGPVITREARDNIRAHVETMEGRGHKVFSVALP
PETEGGWFVAPTMIEIDHPSALEREVFGPVLHVVRYRREERNAMVAAVNALGYALTFGVHSRIDETIAQAVGKAEAGNIY
VNRNIVGAVVGVQPFGGHGLSGTGPKAGGPFYLRRLLARRPMPHGEGEPAPAFTKLVGWMREQGIETAPALRYAAASAFR
DAELPGPVGEQNTLRLKPKGLVLCRAASPEGMWRQVAACLATGNAPLVLCDGAEAEIARMPAEIRPAIAPADAVARAEFS
AVLFEGHRDALIALQMALAERDGPIVPVHALPAEDHSEWDYPLEFLLEEQSISVNTAAAGGNASLMSIG

Specific function: Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon [H]

COG id: COG4230

COG function: function code C; Delta 1-pyrroline-5-carboxylate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI25777736, Length=460, Percent_Identity=31.0869565217391, Blast_Score=181, Evalue=5e-45,
Organism=Homo sapiens, GI25777734, Length=460, Percent_Identity=31.0869565217391, Blast_Score=181, Evalue=5e-45,
Organism=Homo sapiens, GI238859541, Length=463, Percent_Identity=30.8855291576674, Blast_Score=180, Evalue=6e-45,
Organism=Homo sapiens, GI21361176, Length=454, Percent_Identity=30.6167400881057, Blast_Score=164, Evalue=7e-40,
Organism=Homo sapiens, GI25777724, Length=464, Percent_Identity=29.9568965517241, Blast_Score=160, Evalue=7e-39,
Organism=Homo sapiens, GI25777732, Length=461, Percent_Identity=30.58568329718, Blast_Score=160, Evalue=1e-38,
Organism=Homo sapiens, GI153266822, Length=414, Percent_Identity=28.743961352657, Blast_Score=160, Evalue=1e-38,
Organism=Homo sapiens, GI12007648, Length=437, Percent_Identity=28.3752860411899, Blast_Score=157, Evalue=6e-38,
Organism=Homo sapiens, GI25777730, Length=453, Percent_Identity=30.6843267108168, Blast_Score=155, Evalue=2e-37,
Organism=Homo sapiens, GI115387104, Length=430, Percent_Identity=27.4418604651163, Blast_Score=150, Evalue=8e-36,
Organism=Homo sapiens, GI25777728, Length=415, Percent_Identity=29.8795180722892, Blast_Score=147, Evalue=7e-35,
Organism=Homo sapiens, GI4507229, Length=434, Percent_Identity=28.3410138248848, Blast_Score=147, Evalue=1e-34,
Organism=Homo sapiens, GI21614513, Length=424, Percent_Identity=29.4811320754717, Blast_Score=143, Evalue=1e-33,
Organism=Homo sapiens, GI25777721, Length=447, Percent_Identity=27.9642058165548, Blast_Score=139, Evalue=2e-32,
Organism=Homo sapiens, GI188035924, Length=429, Percent_Identity=27.7389277389277, Blast_Score=137, Evalue=5e-32,
Organism=Homo sapiens, GI310128103, Length=429, Percent_Identity=27.7389277389277, Blast_Score=137, Evalue=7e-32,
Organism=Homo sapiens, GI310128093, Length=419, Percent_Identity=27.6849642004773, Blast_Score=137, Evalue=7e-32,
Organism=Homo sapiens, GI238814322, Length=422, Percent_Identity=27.0142180094787, Blast_Score=134, Evalue=6e-31,
Organism=Homo sapiens, GI25952152, Length=431, Percent_Identity=27.1461716937355, Blast_Score=122, Evalue=3e-27,
Organism=Homo sapiens, GI11095441, Length=398, Percent_Identity=26.6331658291457, Blast_Score=119, Evalue=2e-26,
Organism=Homo sapiens, GI310128091, Length=385, Percent_Identity=27.5324675324675, Blast_Score=119, Evalue=2e-26,
Organism=Homo sapiens, GI25777726, Length=463, Percent_Identity=26.5658747300216, Blast_Score=119, Evalue=3e-26,
Organism=Homo sapiens, GI206597441, Length=369, Percent_Identity=27.9132791327913, Blast_Score=117, Evalue=6e-26,
Organism=Homo sapiens, GI206597439, Length=369, Percent_Identity=27.9132791327913, Blast_Score=117, Evalue=6e-26,
Organism=Homo sapiens, GI22907049, Length=369, Percent_Identity=27.9132791327913, Blast_Score=117, Evalue=6e-26,
Organism=Homo sapiens, GI310128087, Length=427, Percent_Identity=25.5269320843091, Blast_Score=103, Evalue=1e-21,
Organism=Homo sapiens, GI71773324, Length=404, Percent_Identity=25.4950495049505, Blast_Score=100, Evalue=7e-21,
Organism=Homo sapiens, GI4502043, Length=402, Percent_Identity=25.6218905472637, Blast_Score=100, Evalue=8e-21,
Organism=Homo sapiens, GI238814371, Length=402, Percent_Identity=25.6218905472637, Blast_Score=100, Evalue=8e-21,
Organism=Homo sapiens, GI4557303, Length=332, Percent_Identity=24.6987951807229, Blast_Score=97, Evalue=1e-19,
Organism=Homo sapiens, GI73466520, Length=332, Percent_Identity=24.3975903614458, Blast_Score=97, Evalue=1e-19,
Organism=Homo sapiens, GI73695881, Length=336, Percent_Identity=25.297619047619, Blast_Score=92, Evalue=4e-18,
Organism=Homo sapiens, GI73695879, Length=336, Percent_Identity=25.297619047619, Blast_Score=92, Evalue=4e-18,
Organism=Homo sapiens, GI310128089, Length=333, Percent_Identity=26.1261261261261, Blast_Score=89, Evalue=3e-17,
Organism=Homo sapiens, GI301500698, Length=426, Percent_Identity=23.4741784037559, Blast_Score=87, Evalue=1e-16,
Organism=Homo sapiens, GI310128095, Length=311, Percent_Identity=27.0096463022508, Blast_Score=82, Evalue=3e-15,
Organism=Homo sapiens, GI310128101, Length=191, Percent_Identity=29.8429319371728, Blast_Score=82, Evalue=3e-15,
Organism=Homo sapiens, GI310128099, Length=190, Percent_Identity=30, Blast_Score=81, Evalue=5e-15,
Organism=Homo sapiens, GI310128097, Length=259, Percent_Identity=26.6409266409266, Blast_Score=75, Evalue=5e-13,
Organism=Escherichia coli, GI1787250, Length=1323, Percent_Identity=59.4104308390023, Blast_Score=1450, Evalue=0.0,
Organism=Escherichia coli, GI1789015, Length=467, Percent_Identity=31.6916488222698, Blast_Score=166, Evalue=9e-42,
Organism=Escherichia coli, GI1788042, Length=428, Percent_Identity=32.2429906542056, Blast_Score=163, Evalue=7e-41,
Organism=Escherichia coli, GI87081896, Length=427, Percent_Identity=31.3817330210773, Blast_Score=160, Evalue=6e-40,
Organism=Escherichia coli, GI1787715, Length=410, Percent_Identity=30.7317073170732, Blast_Score=155, Evalue=1e-38,
Organism=Escherichia coli, GI1787684, Length=459, Percent_Identity=29.8474945533769, Blast_Score=145, Evalue=2e-35,
Organism=Escherichia coli, GI1786504, Length=459, Percent_Identity=28.5403050108932, Blast_Score=140, Evalue=5e-34,
Organism=Escherichia coli, GI1787558, Length=411, Percent_Identity=30.4136253041363, Blast_Score=138, Evalue=2e-33,
Organism=Escherichia coli, GI87082295, Length=430, Percent_Identity=28.6046511627907, Blast_Score=130, Evalue=6e-31,
Organism=Escherichia coli, GI87081926, Length=420, Percent_Identity=25.952380952381, Blast_Score=106, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI17534447, Length=430, Percent_Identity=31.8604651162791, Blast_Score=171, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI115534176, Length=443, Percent_Identity=30.0225733634311, Blast_Score=159, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI25144435, Length=460, Percent_Identity=29.5652173913043, Blast_Score=154, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17562198, Length=458, Percent_Identity=29.4759825327511, Blast_Score=154, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI25143874, Length=456, Percent_Identity=27.8508771929825, Blast_Score=147, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI115532534, Length=338, Percent_Identity=33.1360946745562, Blast_Score=146, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI25143876, Length=456, Percent_Identity=27.8508771929825, Blast_Score=146, Evalue=7e-35,
Organism=Caenorhabditis elegans, GI17534119, Length=455, Percent_Identity=28.5714285714286, Blast_Score=145, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI32564736, Length=408, Percent_Identity=29.4117647058824, Blast_Score=144, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI133930964, Length=418, Percent_Identity=28.2296650717703, Blast_Score=131, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI32564151, Length=381, Percent_Identity=29.6587926509186, Blast_Score=129, Evalue=9e-30,
Organism=Caenorhabditis elegans, GI17551164, Length=436, Percent_Identity=25.2293577981651, Blast_Score=124, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI71995606, Length=464, Percent_Identity=27.3706896551724, Blast_Score=122, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI71986308, Length=404, Percent_Identity=25.990099009901, Blast_Score=121, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI71995613, Length=421, Percent_Identity=27.3159144893112, Blast_Score=115, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI25146391, Length=326, Percent_Identity=24.8466257668712, Blast_Score=99, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI32566756, Length=326, Percent_Identity=24.8466257668712, Blast_Score=99, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI25146394, Length=326, Percent_Identity=24.8466257668712, Blast_Score=99, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71990744, Length=267, Percent_Identity=30.3370786516854, Blast_Score=96, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI17564084, Length=415, Percent_Identity=23.3734939759036, Blast_Score=94, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6321826, Length=477, Percent_Identity=30.188679245283, Blast_Score=184, Evalue=1e-46,
Organism=Saccharomyces cerevisiae, GI6320917, Length=453, Percent_Identity=30.242825607064, Blast_Score=169, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6325196, Length=418, Percent_Identity=29.9043062200957, Blast_Score=167, Evalue=7e-42,
Organism=Saccharomyces cerevisiae, GI6323822, Length=473, Percent_Identity=29.5983086680761, Blast_Score=157, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6323821, Length=471, Percent_Identity=29.5116772823779, Blast_Score=154, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6324950, Length=410, Percent_Identity=26.5853658536585, Blast_Score=150, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6319478, Length=446, Percent_Identity=26.9058295964126, Blast_Score=128, Evalue=6e-30,
Organism=Saccharomyces cerevisiae, GI6321828, Length=487, Percent_Identity=23.2032854209446, Blast_Score=102, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6323757, Length=327, Percent_Identity=24.7706422018349, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI281362580, Length=461, Percent_Identity=30.1518438177874, Blast_Score=174, Evalue=3e-43,
Organism=Drosophila melanogaster, GI62472918, Length=461, Percent_Identity=30.1518438177874, Blast_Score=174, Evalue=3e-43,
Organism=Drosophila melanogaster, GI62472926, Length=461, Percent_Identity=30.1518438177874, Blast_Score=174, Evalue=3e-43,
Organism=Drosophila melanogaster, GI62472936, Length=461, Percent_Identity=30.1518438177874, Blast_Score=174, Evalue=3e-43,
Organism=Drosophila melanogaster, GI21356737, Length=461, Percent_Identity=30.1518438177874, Blast_Score=174, Evalue=3e-43,
Organism=Drosophila melanogaster, GI20129399, Length=418, Percent_Identity=30.1435406698565, Blast_Score=174, Evalue=4e-43,
Organism=Drosophila melanogaster, GI24668425, Length=467, Percent_Identity=27.8372591006424, Blast_Score=167, Evalue=6e-41,
Organism=Drosophila melanogaster, GI24668417, Length=467, Percent_Identity=27.8372591006424, Blast_Score=167, Evalue=6e-41,
Organism=Drosophila melanogaster, GI24668413, Length=467, Percent_Identity=27.8372591006424, Blast_Score=167, Evalue=6e-41,
Organism=Drosophila melanogaster, GI24666674, Length=423, Percent_Identity=29.5508274231678, Blast_Score=148, Evalue=2e-35,
Organism=Drosophila melanogaster, GI28571806, Length=450, Percent_Identity=28.4444444444444, Blast_Score=138, Evalue=2e-32,
Organism=Drosophila melanogaster, GI28571802, Length=450, Percent_Identity=28.4444444444444, Blast_Score=138, Evalue=3e-32,
Organism=Drosophila melanogaster, GI28571800, Length=450, Percent_Identity=28.4444444444444, Blast_Score=138, Evalue=3e-32,
Organism=Drosophila melanogaster, GI28571798, Length=450, Percent_Identity=28.4444444444444, Blast_Score=138, Evalue=3e-32,
Organism=Drosophila melanogaster, GI28571796, Length=450, Percent_Identity=28.4444444444444, Blast_Score=138, Evalue=3e-32,
Organism=Drosophila melanogaster, GI28571794, Length=450, Percent_Identity=28.4444444444444, Blast_Score=138, Evalue=3e-32,
Organism=Drosophila melanogaster, GI24585660, Length=455, Percent_Identity=25.2747252747253, Blast_Score=137, Evalue=6e-32,
Organism=Drosophila melanogaster, GI28574525, Length=460, Percent_Identity=26.0869565217391, Blast_Score=137, Evalue=7e-32,
Organism=Drosophila melanogaster, GI24650465, Length=412, Percent_Identity=27.4271844660194, Blast_Score=136, Evalue=8e-32,
Organism=Drosophila melanogaster, GI24638878, Length=389, Percent_Identity=26.7352185089974, Blast_Score=102, Evalue=2e-21,
Organism=Drosophila melanogaster, GI281360299, Length=338, Percent_Identity=27.5147928994083, Blast_Score=102, Evalue=2e-21,
Organism=Drosophila melanogaster, GI281360297, Length=338, Percent_Identity=27.5147928994083, Blast_Score=102, Evalue=2e-21,
Organism=Drosophila melanogaster, GI281360295, Length=338, Percent_Identity=27.5147928994083, Blast_Score=102, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24586250, Length=338, Percent_Identity=27.5147928994083, Blast_Score=102, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24638876, Length=389, Percent_Identity=26.7352185089974, Blast_Score=102, Evalue=2e-21,
Organism=Drosophila melanogaster, GI281360301, Length=334, Percent_Identity=27.5449101796407, Blast_Score=102, Evalue=2e-21,
Organism=Drosophila melanogaster, GI45552499, Length=338, Percent_Identity=27.5147928994083, Blast_Score=101, Evalue=4e-21,
Organism=Drosophila melanogaster, GI281360303, Length=334, Percent_Identity=27.5449101796407, Blast_Score=101, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005933
- InterPro:   IPR002872 [H]

Pfam domain/function: PF00171 Aldedh; PF01619 Pro_dh [H]

EC number: =1.5.99.8; =1.5.1.12 [H]

Molecular weight: Translated: 135195; Mature: 135064

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVSTMGVKLDDQVRARLRALAEREGRTTHHLAKQLILAGLERLERGEALDAAVTAEDDA
CCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCC
PAAVPFLEFVQDVQPQTVLRAAITAAYRIPETDAVAGLIEGATLPAAAAKQARATATNLV
CCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
TALRARRNAGLVETLLQEYALSSHEGIALMCLAEALLRIPDAATRDALIRDKIGAGDWQS
HHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHH
HLGGNKSVFINAATWGLLLTGRLNATASEAGLSSALTRLLARGGEPVVRRGVNIAMRLMG
HCCCCCEEEEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
EQFVMGRTIGEALANARKREAKGFAYSYDMLGEAALTAADAARYYRDYEQAIHAIGAAAG
HHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GKGIYRGPGISVKLSALHPRYCRAQRARVMEELAPRLKALALLARRYDIGINIDAEEADR
CCCCEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCC
LDLSLDLLEGLCFEPGLAGWNGIGFVVQAYQKRARSVIEFLIDLARRSRHRLMVRLVKGA
CCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
YWDSEIKRAQLDGLEGFPVFTRKIHTDLSYLACARAMLAARTEIFPQFATHNALTLASIH
CCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
ALAGPAFEVGDYEFQCLHGMGEPLYEEVVGPQKLDRPCRIYAPVGTHETLLAYLVRRLLE
HHCCCCEECCCCHHHHHHCCCCHHHHHHCCHHHCCCCEEEEECCCCHHHHHHHHHHHHHH
NGANTSFVNRLADRRVPVEALIEDPVAAARKIEPLGAPHPKIALPGAILGTRRNSAGFDL
CCCCHHHHHHHHHCCCCHHHHHHCHHHHHHHCCCCCCCCCCEECCCHHEECCCCCCCCCC
TSEQRLASLGSALLASLEQDWRAAPPDADPAAPGRTVVNPANIADRVGTVIEPDAGAVGA
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECHHHHHHHCCCCCCCCCCHHHH
ALARAAAMAPIWQATPAAERAAILLRAADLLEHRMTALVGLIVREAGKSLPAAIGEVREA
HHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
VDFMRYYAGQLQDGFDNETHRPLGVVAAISPWNFPLAIFTGQVVAALAAGNVVLAKPAEE
HHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEECCCCC
TPLIAAQGVRIMHEAGVPADALQLLPGDGRTGAALVGDARVGGVVFTGSTAVARLIQATL
CCCCHHCCCHHHHHCCCCHHHHHHCCCCCCCCCEEEECCCCCCEEEECCHHHHHHHHHHH
ARRLDADGMPVPLIAETGGQNAMLVDSSALLEQAVGDIVTSAFDSAGQRCSALRILLVQD
HHHCCCCCCCCEEEECCCCCCEEEECHHHHHHHHHHHHHHHHHHHHCCHHHHEEEEEECC
DIADPLLAMLRGAMEELAVGATDRLSSDVGPVITREARDNIRAHVETMEGRGHKVFSVAL
CHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEC
PPETEGGWFVAPTMIEIDHPSALEREVFGPVLHVVRYRREERNAMVAAVNALGYALTFGV
CCCCCCCEEEECEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HSRIDETIAQAVGKAEAGNIYVNRNIVGAVVGVQPFGGHGLSGTGPKAGGPFYLRRLLAR
HHHHHHHHHHHHCCCCCCCEEEECCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHH
RPMPHGEGEPAPAFTKLVGWMREQGIETAPALRYAAASAFRDAELPGPVGEQNTLRLKPK
CCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCC
GLVLCRAASPEGMWRQVAACLATGNAPLVLCDGAEAEIARMPAEIRPAIAPADAVARAEF
CEEEEECCCCCHHHHHHHHHHHCCCCCEEEECCCCHHHHHCCHHHCCCCCCHHHHHHHHH
SAVLFEGHRDALIALQMALAERDGPIVPVHALPAEDHSEWDYPLEFLLEEQSISVNTAAA
HHHHHCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCHHHHCCCCCCEEEEECC
GGNASLMSIG
CCCCEEEECC
>Mature Secondary Structure 
AVSTMGVKLDDQVRARLRALAEREGRTTHHLAKQLILAGLERLERGEALDAAVTAEDDA
CCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCC
PAAVPFLEFVQDVQPQTVLRAAITAAYRIPETDAVAGLIEGATLPAAAAKQARATATNLV
CCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
TALRARRNAGLVETLLQEYALSSHEGIALMCLAEALLRIPDAATRDALIRDKIGAGDWQS
HHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHH
HLGGNKSVFINAATWGLLLTGRLNATASEAGLSSALTRLLARGGEPVVRRGVNIAMRLMG
HCCCCCEEEEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
EQFVMGRTIGEALANARKREAKGFAYSYDMLGEAALTAADAARYYRDYEQAIHAIGAAAG
HHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GKGIYRGPGISVKLSALHPRYCRAQRARVMEELAPRLKALALLARRYDIGINIDAEEADR
CCCCEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCC
LDLSLDLLEGLCFEPGLAGWNGIGFVVQAYQKRARSVIEFLIDLARRSRHRLMVRLVKGA
CCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
YWDSEIKRAQLDGLEGFPVFTRKIHTDLSYLACARAMLAARTEIFPQFATHNALTLASIH
CCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
ALAGPAFEVGDYEFQCLHGMGEPLYEEVVGPQKLDRPCRIYAPVGTHETLLAYLVRRLLE
HHCCCCEECCCCHHHHHHCCCCHHHHHHCCHHHCCCCEEEEECCCCHHHHHHHHHHHHHH
NGANTSFVNRLADRRVPVEALIEDPVAAARKIEPLGAPHPKIALPGAILGTRRNSAGFDL
CCCCHHHHHHHHHCCCCHHHHHHCHHHHHHHCCCCCCCCCCEECCCHHEECCCCCCCCCC
TSEQRLASLGSALLASLEQDWRAAPPDADPAAPGRTVVNPANIADRVGTVIEPDAGAVGA
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECHHHHHHHCCCCCCCCCCHHHH
ALARAAAMAPIWQATPAAERAAILLRAADLLEHRMTALVGLIVREAGKSLPAAIGEVREA
HHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
VDFMRYYAGQLQDGFDNETHRPLGVVAAISPWNFPLAIFTGQVVAALAAGNVVLAKPAEE
HHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEECCCCC
TPLIAAQGVRIMHEAGVPADALQLLPGDGRTGAALVGDARVGGVVFTGSTAVARLIQATL
CCCCHHCCCHHHHHCCCCHHHHHHCCCCCCCCCEEEECCCCCCEEEECCHHHHHHHHHHH
ARRLDADGMPVPLIAETGGQNAMLVDSSALLEQAVGDIVTSAFDSAGQRCSALRILLVQD
HHHCCCCCCCCEEEECCCCCCEEEECHHHHHHHHHHHHHHHHHHHHCCHHHHEEEEEECC
DIADPLLAMLRGAMEELAVGATDRLSSDVGPVITREARDNIRAHVETMEGRGHKVFSVAL
CHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEC
PPETEGGWFVAPTMIEIDHPSALEREVFGPVLHVVRYRREERNAMVAAVNALGYALTFGV
CCCCCCCEEEECEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HSRIDETIAQAVGKAEAGNIYVNRNIVGAVVGVQPFGGHGLSGTGPKAGGPFYLRRLLAR
HHHHHHHHHHHHCCCCCCCEEEECCEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHH
RPMPHGEGEPAPAFTKLVGWMREQGIETAPALRYAAASAFRDAELPGPVGEQNTLRLKPK
CCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCC
GLVLCRAASPEGMWRQVAACLATGNAPLVLCDGAEAEIARMPAEIRPAIAPADAVARAEF
CEEEEECCCCCHHHHHHHHHHHCCCCCEEEECCCCHHHHHCCHHHCCCCCCHHHHHHHHH
SAVLFEGHRDALIALQMALAERDGPIVPVHALPAEDHSEWDYPLEFLLEEQSISVNTAAA
HHHHHCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCHHHHCCCCCCEEEEECC
GGNASLMSIG
CCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7966312; 8905232; 9278503; 3325781; 12514740 [H]