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The map label for this gene is tdcB [H]

Identifier: 148259920

GI number: 148259920

Start: 1003139

End: 1004335

Strand: Reverse

Name: tdcB [H]

Synonym: Acry_0909

Alternate gene names: 148259920

Gene position: 1004335-1003139 (Counterclockwise)

Preceding gene: 148259921

Following gene: 148259916

Centisome position: 29.63

GC content: 72.35

Gene sequence:

>1197_bases
TTGGTCACCCTCGCCGATATCGAGGCGGCGGCCGGCCGGATCGCCGGCGCGGTGCTGCGCACGCCGCTGGTCCGCGCCGA
CGCGCTCTCGCGCGCGACCGGTGCTGACATCCATCTCAAGCTCGAGAACCTGCAGGCCACCGGCGCCTTCAAGGAACGGG
GGGCGGCAAACCGCATCGCCCTGCTGACGGAGGCCGAGCGCAAGTCCGGCGTGATCGCGATGTCGGCCGGCAATCACGCC
CAGGCGGTGGCGCGCCACGCCCAGCTCGCCGGCATCCGCGCCACCATCGTGATGCCGCGCTTCACCCCGACCACGAAGGT
CACCCGCACCCGGGCCTGGGGCGCGCAGGTGGTGCTGCACGGCGAAACCCTCGCCGAGGCCGCCGCCCACGCCCATGAAC
TCGCCGCCCGCGAAGGCCTGGTCTTCGTCCACCCCTACGACGACGCGGACGTGATCGCCGGCCAGGGCACGCTCGCCCTC
GAGGTGATCCATGACCTGCCGGATCTCGACGCGCTGGTGATCCCGACCGGCGGCGGCGGTTTCATCTCCGGCTGCGCGGT
GGCGGCGCGGGCGCTGCGCCCCCGCGTCGAGATCCTCGGCGTCGAGGTCGAAAGCTATGCCGGCTTTGCCCAGGCGCTCG
CGGGCCAGGAGGTCAAGGTCGGCGGCGCGACCATCGCCGAGGGCATCGCGGTGCGCGATATCGGCCAGCTGCCGCTCGCG
CTGCTGAAGGAACACGAGGTCGAGGTTCTGGTCGTGCCGGAAGCGGCGGTCGAGCAGGCGATCGCGATGCTGGCCGAGAG
CGGCAAGATCGTCGCCGAGGGCGCCGGCGCCGCCGCCCTCGCCGCGGTGCTGACCTTCCCGCAGCGCTTCGCCGGCCGCC
GGCTCGCCCTGCCGATCTGCGGCGGCAATATCGACACCCGCGTCCTCGCCAACACGCTACTGCGCAACCTGATGCGCGAC
GGGCGGATCGTGAAGGTGCTGATGGAAATCCCGGACCGCCCCGGCGTGCTGGCCGACATCGCCGCCCGCATCGGCGATCA
GGGCGGCAACATCATCGAGGTCGTGCACCAGCGCCAGTTCGCCTCGCCGACCGTGCAGGCCGCGCATCTCGAAGTGATGT
TCGAGGCGCGCGACGCCGCCCATGGCCGCTCCATCACCGAGGCGCTGGAAGCCGCCTACACCGTCCGCCGGCTCTGA

Upstream 100 bases:

>100_bases
AAGTCGCTGATCGGCAAGAAGCCGGGAGACACCGTTTCGGTGCCCGCCCCCGGCGGCGACCGCAGCTACGAGATCCTCGC
CGTCCGGTTCGGCTGAGGCC

Downstream 100 bases:

>100_bases
TCGCGCCAGCCGGCGCTCAGATCACGAAGGCGCCGCCGCGCATCACCGGCGTGATGGTGCCGTCGGCGTTCACGCCATCG
ACGTCCATCAGCGCCGAGCC

Product: threonine dehydratase

Products: NA

Alternate protein names: Threonine deaminase [H]

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MVTLADIEAAAGRIAGAVLRTPLVRADALSRATGADIHLKLENLQATGAFKERGAANRIALLTEAERKSGVIAMSAGNHA
QAVARHAQLAGIRATIVMPRFTPTTKVTRTRAWGAQVVLHGETLAEAAAHAHELAAREGLVFVHPYDDADVIAGQGTLAL
EVIHDLPDLDALVIPTGGGGFISGCAVAARALRPRVEILGVEVESYAGFAQALAGQEVKVGGATIAEGIAVRDIGQLPLA
LLKEHEVEVLVVPEAAVEQAIAMLAESGKIVAEGAGAAALAAVLTFPQRFAGRRLALPICGGNIDTRVLANTLLRNLMRD
GRIVKVLMEIPDRPGVLADIAARIGDQGGNIIEVVHQRQFASPTVQAAHLEVMFEARDAAHGRSITEALEAAYTVRRL

Sequences:

>Translated_398_residues
MVTLADIEAAAGRIAGAVLRTPLVRADALSRATGADIHLKLENLQATGAFKERGAANRIALLTEAERKSGVIAMSAGNHA
QAVARHAQLAGIRATIVMPRFTPTTKVTRTRAWGAQVVLHGETLAEAAAHAHELAAREGLVFVHPYDDADVIAGQGTLAL
EVIHDLPDLDALVIPTGGGGFISGCAVAARALRPRVEILGVEVESYAGFAQALAGQEVKVGGATIAEGIAVRDIGQLPLA
LLKEHEVEVLVVPEAAVEQAIAMLAESGKIVAEGAGAAALAAVLTFPQRFAGRRLALPICGGNIDTRVLANTLLRNLMRD
GRIVKVLMEIPDRPGVLADIAARIGDQGGNIIEVVHQRQFASPTVQAAHLEVMFEARDAAHGRSITEALEAAYTVRRL
>Mature_398_residues
MVTLADIEAAAGRIAGAVLRTPLVRADALSRATGADIHLKLENLQATGAFKERGAANRIALLTEAERKSGVIAMSAGNHA
QAVARHAQLAGIRATIVMPRFTPTTKVTRTRAWGAQVVLHGETLAEAAAHAHELAAREGLVFVHPYDDADVIAGQGTLAL
EVIHDLPDLDALVIPTGGGGFISGCAVAARALRPRVEILGVEVESYAGFAQALAGQEVKVGGATIAEGIAVRDIGQLPLA
LLKEHEVEVLVVPEAAVEQAIAMLAESGKIVAEGAGAAALAAVLTFPQRFAGRRLALPICGGNIDTRVLANTLLRNLMRD
GRIVKVLMEIPDRPGVLADIAARIGDQGGNIIEVVHQRQFASPTVQAAHLEVMFEARDAAHGRSITEALEAAYTVRRL

Specific function: Acts on both serine and threonine, and properly considered as a hydroxy amino acid deaminase [H]

COG id: COG1171

COG function: function code E; Threonine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serine/threonine dehydratase family [H]

Homologues:

Organism=Homo sapiens, GI11345492, Length=321, Percent_Identity=33.6448598130841, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI33469958, Length=304, Percent_Identity=29.2763157894737, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI19923959, Length=306, Percent_Identity=30.0653594771242, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI1789505, Length=308, Percent_Identity=38.3116883116883, Blast_Score=201, Evalue=6e-53,
Organism=Escherichia coli, GI1790207, Length=331, Percent_Identity=37.4622356495468, Blast_Score=160, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI71991565, Length=396, Percent_Identity=38.1313131313131, Blast_Score=239, Evalue=2e-63,
Organism=Caenorhabditis elegans, GI17537387, Length=396, Percent_Identity=32.8282828282828, Blast_Score=191, Evalue=6e-49,
Organism=Caenorhabditis elegans, GI17508781, Length=317, Percent_Identity=30.2839116719243, Blast_Score=137, Evalue=9e-33,
Organism=Saccharomyces cerevisiae, GI6322631, Length=313, Percent_Identity=37.3801916932907, Blast_Score=185, Evalue=1e-47,
Organism=Saccharomyces cerevisiae, GI6320930, Length=339, Percent_Identity=33.0383480825959, Blast_Score=146, Evalue=7e-36,
Organism=Saccharomyces cerevisiae, GI6319788, Length=283, Percent_Identity=27.5618374558304, Blast_Score=92, Evalue=1e-19,
Organism=Drosophila melanogaster, GI21355833, Length=399, Percent_Identity=37.0927318295739, Blast_Score=211, Evalue=8e-55,
Organism=Drosophila melanogaster, GI24645328, Length=303, Percent_Identity=35.6435643564356, Blast_Score=140, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR000634
- InterPro:   IPR005789 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.3.1.19 [H]

Molecular weight: Translated: 41648; Mature: 41648

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTLADIEAAAGRIAGAVLRTPLVRADALSRATGADIHLKLENLQATGAFKERGAANRIA
CEEEECHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEEEECCEECCCHHHCCCCCEEE
LLTEAERKSGVIAMSAGNHAQAVARHAQLAGIRATIVMPRFTPTTKVTRTRAWGAQVVLH
EEEECHHHCCEEEEECCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCEEEECCCEEEEEE
GETLAEAAAHAHELAAREGLVFVHPYDDADVIAGQGTLALEVIHDLPDLDALVIPTGGGG
CHHHHHHHHHHHHHHHHCCEEEEECCCCCCEEECCCCEEEHHHHCCCCCCEEEEECCCCC
FISGCAVAARALRPRVEILGVEVESYAGFAQALAGQEVKVGGATIAEGIAVRDIGQLPLA
HHHHHHHHHHHHCCCEEEEEEEHHHHHHHHHHHCCCEEEECCHHHHCCCCHHHHHHCHHH
LLKEHEVEVLVVPEAAVEQAIAMLAESGKIVAEGAGAAALAAVLTFPQRFAGRRLALPIC
HHCCCCEEEEEECHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHCCCEEEEEEE
GGNIDTRVLANTLLRNLMRDGRIVKVLMEIPDRPGVLADIAARIGDQGGNIIEVVHQRQF
CCCCHHHHHHHHHHHHHHHCCCEEEHEECCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHC
ASPTVQAAHLEVMFEARDAAHGRSITEALEAAYTVRRL
CCCCHHHEEEEEEEEHHHCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVTLADIEAAAGRIAGAVLRTPLVRADALSRATGADIHLKLENLQATGAFKERGAANRIA
CEEEECHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEEEECCEECCCHHHCCCCCEEE
LLTEAERKSGVIAMSAGNHAQAVARHAQLAGIRATIVMPRFTPTTKVTRTRAWGAQVVLH
EEEECHHHCCEEEEECCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCEEEECCCEEEEEE
GETLAEAAAHAHELAAREGLVFVHPYDDADVIAGQGTLALEVIHDLPDLDALVIPTGGGG
CHHHHHHHHHHHHHHHHCCEEEEECCCCCCEEECCCCEEEHHHHCCCCCCEEEEECCCCC
FISGCAVAARALRPRVEILGVEVESYAGFAQALAGQEVKVGGATIAEGIAVRDIGQLPLA
HHHHHHHHHHHHCCCEEEEEEEHHHHHHHHHHHCCCEEEECCHHHHCCCCHHHHHHCHHH
LLKEHEVEVLVVPEAAVEQAIAMLAESGKIVAEGAGAAALAAVLTFPQRFAGRRLALPIC
HHCCCCEEEEEECHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHCCCEEEEEEE
GGNIDTRVLANTLLRNLMRDGRIVKVLMEIPDRPGVLADIAARIGDQGGNIIEVVHQRQF
CCCCHHHHHHHHHHHHHHHCCCEEEHEECCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHC
ASPTVQAAHLEVMFEARDAAHGRSITEALEAAYTVRRL
CCCCHHHEEEEEEEEHHHCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA